Shepherd's Purse - Acetaminophen, Butalbital, Caffeine, Codeine Interaction
Herbal: Shepherd's Purse
Also Known As: Capsella bursa-pastoris, Blind Weed, Bolsa del Pastor, Bolsa-de-Pastor, Bourse à Berger, Bourse-à-Pasteur, Bourse de Capucin, Boursette, Bursae Pastoris Herba, Capsella, Capselle, Capselle a Pasteur, Capselle Bourse-à-Pasteur, Caseweed, Cocowort, Corne de Lion, Erva-Do-B
Drug: Acetaminophen, Butalbital, Caffeine, Codeine
Brand names:
Esgic with Codeine, Fioricet w/ Codeine
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Acetaminophen, Butalbital, Caffeine, Codeine is classified as belonging to the following category: Cns Depressants
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Shepherd's Purse Overview
Shepherd's purse (Capsella bursa-pastoris) is a flowering plant belonging to the mustard family. It is native to Europe and Asia, but has become invasive in many other parts of the world. The leaves are oblong in shape and the seeds are contained in a small, triangular-shaped capsule that resembles a purse, thus the name "shepherd's purse."
Shepherd's purse has been used in traditional medicine for its astringent, diuretic, and tonic properties. It has to been used to treat a number of conditions, including bleeding disorders, digestive problems, and kidney problems. It is also sometimes used as a natural remedy for heavy menstrual periods.
Shepherd's Purse - More Interactions
Shepherd's Purse interacts with 263 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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