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Dietary supplement

Organic Guava Leaf Extract Ingredients & Drug Interactions

by Herbal Goodness

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Organic Guava Leaf Extract is a dietary supplement by Herbal Goodness with 1 active ingredient. Its ingredients are commonly taken for diarrhea and digestive upset, blood sugar support, cholesterol support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Guava Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Organic Guava Leaf Extract by Herbal Goodness

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This is a single-ingredient product: guava leaf extract in liquid form, with glycerin and purified water as inactive ingredients. Guava leaf extract comes from the leaves of the guava plant and has been used traditionally to support various health concerns, though the evidence for most of them isn't yet established in our data.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: gentle natural sleep aid and metabolism support.
  • We looked for evidence on: Sleep quality, Metabolic health, Blood pressure regulation, Antioxidant support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold does not establish effectiveness for any of the uses listed—diarrhea, gum inflammation (gingivitis), high blood pressure, or knee pain all carry a rating of insufficient reliable evidence. This means there's not yet enough solid data to say whether this extract works for these purposes.

If you're considering it for a specific health goal, talk with your pharmacist or doctor about what the current science supports.

The evidence, ingredient by ingredient Guava

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Guava fruit as a food is generally well tolerated, but concentrated leaf supplements like this one are less studied, so caution is warranted. Taken by mouth, guava leaf extract may cause temporary belly pain or nausea in some people.

Applied to skin, it can trigger contact dermatitis or, in people with eczema (atopic dermatitis), may make the condition worse—one case reported a teenager's eczema flared after bathing with guava leaf tea bags and improved once he stopped. The safety data we hold for concentrated leaf supplements is limited.

Side effects, ingredient by ingredient Guava

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Guava.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood sugar medications—especially antidiabetes drugs like glimepiride—before you take this product. Guava leaf extract can lower blood sugar, which may combine with your medication and cause low blood sugar.

Monitor your glucose and talk to your doctor about whether a medication adjustment is needed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best for someone aware of the diabetes medication interaction and willing to monitor their blood glucose carefully—or someone not taking antidiabetes drugs. If you take diabetes medication, check with your pharmacist before starting.

The evidence for its other claimed uses isn't yet established. The safety profile for concentrated leaf supplements is still being studied.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Guava Leaf Extract, straight from the product label.

Brand Herbal Goodness
Barcode (UPC) 850035852538
Net contents 12 Fluid Ounce(s); 354 mL
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 303506
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Guava Leaf Extract by Herbal Goodness, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
23
UPC/BARCODE
850035852538
IngredientAmount% DV
Guava Leaf Extract0 NP--

Other ingredients: Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Guava Leaf Extract is hailed as a super herb with many health benefits. A gentle and natural sleep aid, healthy metabolism and blood pressure support. Guava leaves are rich in Vitamin C, lycopene, flavonoids such as quercetin, antioxidants that are beneficial for healthy skin, provide anti-aging, and hair re-growth benefits.

Organic Guava Leaf 15x liquid extract

Certified Kosher by Earth Kosher

General Statements

100% women-owned, 10% of profits donated &, FairTrade Practices

Impact We do right by others We believe in business for social good and give 10% of profits to support the education of African girls. Sustainability We respect mother earth We believe in the environment and support our farmers through fairtrade practices.

100% satisfaction guaranteed Questions or comments? Instagram herbalgoodnessco Twitter herbal_goodness Visit herbalgoodnessco.com for a complete line of products

Formulation

Quality We only use the best Made from the best quality herbs, our products are tested to the highest standard by 3rd party certifiers.

Made with Non-GMO ingredients

Fairly traded

Concentrated 15x extra strength Healthy metabolism & sleep aid support

USDA Organic

Certified Organic by Oregon Tilth

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

USDA Organic

EarthKosher

Packaged in the USA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 tablespoon, 2 to 3 times a day with food. May be diluted with water or juice.

Storage

Warning: Store tightly closed in a cool dry place.

Precautions

Do not use if inner seal of tamper evident seal is broken.

If pregnant or have a medical condition, consult your physician before using this herbal product.

See for yourself

Organic Guava Leaf Extract by Herbal Goodness label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic Guava Leaf Extract by Herbal Goodness

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container23 Amounts shown are per serving.

Guava Leaf Extract

Interacts with
86 drugs
0 NP per serving

Guava is a tropical fruit tree whose leaves and fruit have a long history of folk use for diarrhea, blood sugar, and general wellness. The fruit is a...

Guava Leaf Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Guava Leaf Extract by Herbal Goodness Drug Interactions

Want to check YOUR meds against Organic Guava Leaf Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Guava Leaf Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Guava Leaf Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, concomitant use with antidiabetes drugs might have additive effects and increase the risk of hypoglycemia. Animal research shows that guava leaf extract or guava fruit can have hypoglycemic effects. Monitor blood glucose levels closely. Medication dose adjustments may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, metformin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Organic Guava Leaf Extract, from the product label.

Herbal Goodness

See all Herbal Goodness products
Name
Herbal Goodness
Street Address
2150 S. Central Expressway, Suite 200
City
McKinney
State
TX
ZipCode
75070
Phone Number
800-820-4829
Web Address
herbalgoodnessco.com
Pharmacist Counseling Corner

Organic Guava Leaf Extract by Herbal Goodness: Common Questions

Does Organic Guava Leaf Extract by Herbal Goodness interact with any medications?
Yes. Based on its ingredients, Organic Guava Leaf Extract has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Guava Leaf Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on diabetes medication?
Not without checking with your pharmacist first. Guava leaf extract can lower blood sugar, and mixing it with diabetes drugs raises the risk of low blood sugar. You may be able to take it, but your doctor or pharmacist will need to monitor your blood glucose closely and may adjust your medication dose.
What side effects might I experience?
Taken by mouth, some people report temporary belly pain or nausea. If you apply it to your skin, it can cause a rash or contact dermatitis. If you have eczema, applying guava leaf extract may make it worse.
Does this actually work for diarrhea, high blood pressure, or other conditions listed?
The evidence we have isn't strong enough to say. All the uses listed—diarrhea, gum inflammation, high blood pressure, and knee pain—are rated insufficient reliable evidence. Talk with your pharmacist or doctor about what the science currently supports for your specific need.
Is it safe if I'm not pregnant or breastfeeding?
Guava fruit as a food is generally well tolerated, but concentrated leaf supplements like this one are less studied. The main caution is the interaction with diabetes drugs and the possible side effects listed. Beyond that, safety data on leaf supplements is limited, so talk with your pharmacist about whether it's right for you.
What's in this besides the guava leaf extract?
Glycerin and purified water—those are the inactive ingredients that help deliver the extract. The only active ingredient is the guava leaf extract itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Guava Leaf Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Guava Leaf Extract label
Go deeper

The Full Monographs Behind Organic Guava Leaf Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Organic Guava Leaf Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Guava 7 references
  1. Lozoya, X., Reyes-Morales, H., Chavez-Soto, M. A., Martinez-Garcia, Mdel C., Soto-Gonzalez, Y., and Doubova, S. V. Intestinal anti-spasmodic effect of a phytodrug of Psidium guajava folia in the treatment of acute diarrheic disease. J Ethnopharmacol 2002 PubMed
  2. Obi M, Miyazaki Y, Yokozeki H, Nishioka K. Allergic contact dermatitis due to guava tea. Contact Dermatitis. 2001;44(2):116-7. PubMed
  3. Singh RB, Rastogi SS, Singh R, Ghosh S, Niaz MA. Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure. Am J Cardiol. 1992;70(15):1287-91. PubMed
  4. Nayak N, Varghese J, Shetty S, et al. Evaluation of a mouthrinse containing guava leaf extract as part of comprehensive oral care regimen- a randomized placebo-controlled clinical trial. BMC Complement Altern Med. 2019;19(1):327. PubMed
  5. Kakuo S, Fushimi T, Kawasaki K, Nakamura J, Ota N. Effects of Psidium guajava Linn. Leaf extract in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study. Aging Clin Exp Res. 2018;30(11):1391-1398. PubMed
  6. Gutiérrez RM, Mitchell S, Solis RV. Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2008;117(1):1-27. PubMed
  7. Doubova SV, Morales HR, Hernández SF, et al. Effect of a Psidii guajavae folium extract in the treatment of primary dysmenorrhea: a randomized clinical trial. J Ethnopharmacol. 2007;110(2):305-10. PubMed

See these in context on the Guava monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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