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Dietary supplement

Original Guava Leaf Extract 700 mg Ingredients & Drug Interactions

by Herbal Goodness

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Original Guava Leaf Extract 700 mg is a dietary supplement by Herbal Goodness with 1 active ingredient. Its ingredients are commonly taken for diarrhea and digestive upset, blood sugar support, cholesterol support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Guava Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Original Guava Leaf Extract 700 mg by Herbal Goodness

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: guava leaf extract at 700 mg per capsule. The other ingredients — pullulan and rice — are inactive fillers that help make and shape the capsule.

Guava leaf has been used traditionally for digestive and other health purposes, though the science supporting those uses isn't yet solid.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: promote healthy blood sugar and heart health.
  • We looked for evidence on: Blood sugar regulation, Cardiovascular health, Cholesterol management.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence on guava leaf extract is still thin. Our data shows insufficient reliable evidence to rate it for diarrhea, gingivitis, high blood pressure, or knee pain.

That doesn't mean it doesn't work — it means research hasn't yet nailed down whether it does, how well, or in what doses.

The evidence, ingredient by ingredient Guava

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Guava fruit eaten as food is generally well tolerated. Leaf extracts and supplements, though, are less studied, and caution is advised.

When taken by mouth, guava leaf extract may cause transient abdominal pain or nausea in some people. Applied to skin, it can cause contact dermatitis or, in people with atopic dermatitis (eczema), may worsen the condition — one case reported a teenager's eczema flaring after bathing with guava leaf tea.

For breastfeeding, guava leaf is likely safe based on the data we hold. There's no safety data on file for pregnancy.

Side effects, ingredient by ingredient Guava

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Guava.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug — such as glimepiride or others in that class — check with your doctor or pharmacist before adding this product. Guava leaf extract may lower blood sugar, and combined with your medication, that could drop it too far.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is a single-ingredient product and generally well tolerated by mouth, though nausea or mild stomach pain can happen. The main thing to watch: if you take any blood sugar–lowering medication, you need to talk with your doctor or pharmacist before starting it, because guava leaf may lower blood sugar further.

The evidence for what it's marketed for isn't yet solid enough to say whether it'll help you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Original Guava Leaf Extract 700 mg, straight from the product label.

Brand Herbal Goodness
Barcode (UPC) 798304441574
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 261281
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Original Guava Leaf Extract 700 mg by Herbal Goodness, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
798304441574
IngredientAmount% DV
Guava Leaf Extract700 mg--

Other ingredients: Pullulan, Rice

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Guava Leaf Extract is a gentle and natural way to promote healthy blood sugar, support a healthy heart and improve gastrointestinal functions.

Approved Keto Friendly

Certified Kosher by Orthodox Union

Original Guava Leaf Extract 700 mg/capsule

General Statements

100% women owned, 10% of profits & ethical trade Quality We Only Use the Best Made from the highest quality herbs, our products are tested to the highest standard by 3rd party certifiers. Impact We Do Right By Others We believe in business for social good and give 10% of profits to support the education of African girls. Sustainability We Respect Mother Earth We believe in the environment and support and fairtrade practices.

Instagram herbalgoodnessco Twitter herbal_goodness Visit herbalgoodnessco.com to learn more

Seals/Symbols

Packaged in the USA

OU (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Sleep Aid & Blood Sugar Support

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 capsule with meal or as directed by a qualified health care professional.

Storage

Warning: Store tightly closed in a cool, dry place.

Precautions

Do not use if inner seal or tamper evident seal is broken.

If pregnant or have a medical condition, consult your physician before using this herbal product.

See for yourself

Original Guava Leaf Extract 700 mg by Herbal Goodness label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Original Guava Leaf Extract 700 mg by Herbal Goodness

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Guava Leaf Extract

Interacts with
86 drugs
700 mg per serving Form: Psidium guajava L. Leaf Extract

Guava is a tropical fruit tree whose leaves and fruit have a long history of folk use for diarrhea, blood sugar, and general wellness. The fruit is a...

Guava Leaf Extract monograph & interactions

Other (inactive) ingredients: Pullulan, Rice. These complete the product’s ingredient list but are not active constituents.

Interaction report

Original Guava Leaf Extract 700 mg by Herbal Goodness Drug Interactions

Want to check YOUR meds against Original Guava Leaf Extract 700 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Original Guava Leaf Extract 700 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Guava Leaf Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, concomitant use with antidiabetes drugs might have additive effects and increase the risk of hypoglycemia. Animal research shows that guava leaf extract or guava fruit can have hypoglycemic effects. Monitor blood glucose levels closely. Medication dose adjustments may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, metformin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Original Guava Leaf Extract 700 mg, from the product label.

Herbal Goodness

See all Herbal Goodness products
Name
Herbal Goodness
Street Address
2150 S. Central Expressway, Suite 200
City
McKinney
State
TX
ZipCode
75070
Phone Number
800-820-4829
Web Address
herbalgoodnessco.com
Pharmacist Counseling Corner

Original Guava Leaf Extract 700 mg by Herbal Goodness: Common Questions

Does Original Guava Leaf Extract 700 mg by Herbal Goodness interact with any medications?
Yes. Based on its ingredients, Original Guava Leaf Extract 700 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Original Guava Leaf Extract 700 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will guava leaf extract help my blood sugar?
Animal research suggests guava leaf extract might lower blood sugar, which is why we caution against pairing it with antidiabetes drugs. But we don't have enough reliable evidence to say whether it'll actually help people manage their blood sugar or treat diabetes. This is something to discuss with your doctor.
Can I take this while breastfeeding?
Guava leaf is likely safe during breastfeeding based on our data. If you have other questions specific to your situation, talk with your doctor or pharmacist.
What side effects might I notice?
By mouth, you may experience transient abdominal pain or nausea. If you apply it to skin, it can cause contact dermatitis (skin irritation). If you have eczema or atopic dermatitis, be cautious — topical use has been reported to worsen those conditions.
Why does the label say guava leaf extract is 'less studied' than guava fruit?
Guava fruit as food has been eaten for a long time and is well tolerated. Concentrated leaf extracts and supplements are newer and haven't been tested as thoroughly in people, so we know less about their long-term safety.
Is there anything else in this capsule besides guava leaf?
The capsule also contains pullulan and rice, which are inactive fillers used to make the supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Original Guava Leaf Extract 700 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Original Guava Leaf Extract 700 mg label
Go deeper

The Full Monographs Behind Original Guava Leaf Extract 700 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Original Guava Leaf Extract 700 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Guava 7 references
  1. Lozoya, X., Reyes-Morales, H., Chavez-Soto, M. A., Martinez-Garcia, Mdel C., Soto-Gonzalez, Y., and Doubova, S. V. Intestinal anti-spasmodic effect of a phytodrug of Psidium guajava folia in the treatment of acute diarrheic disease. J Ethnopharmacol 2002 PubMed
  2. Obi M, Miyazaki Y, Yokozeki H, Nishioka K. Allergic contact dermatitis due to guava tea. Contact Dermatitis. 2001;44(2):116-7. PubMed
  3. Singh RB, Rastogi SS, Singh R, Ghosh S, Niaz MA. Effects of guava intake on serum total and high-density lipoprotein cholesterol levels and on systemic blood pressure. Am J Cardiol. 1992;70(15):1287-91. PubMed
  4. Nayak N, Varghese J, Shetty S, et al. Evaluation of a mouthrinse containing guava leaf extract as part of comprehensive oral care regimen- a randomized placebo-controlled clinical trial. BMC Complement Altern Med. 2019;19(1):327. PubMed
  5. Kakuo S, Fushimi T, Kawasaki K, Nakamura J, Ota N. Effects of Psidium guajava Linn. Leaf extract in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study. Aging Clin Exp Res. 2018;30(11):1391-1398. PubMed
  6. Gutiérrez RM, Mitchell S, Solis RV. Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2008;117(1):1-27. PubMed
  7. Doubova SV, Morales HR, Hernández SF, et al. Effect of a Psidii guajavae folium extract in the treatment of primary dysmenorrhea: a randomized clinical trial. J Ethnopharmacol. 2007;110(2):305-10. PubMed

See these in context on the Guava monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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