Forskolin Extract Ingredients & Drug Interactions
by Herbadiet
What is this page for?
First and foremost: checking Forskolin Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Forskolin Extract is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for weight management, asthma and breathing, high blood pressure.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Coleus forskohlii extract powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Forskolin Extract by Herbadiet
Ask about any prescription or over-the-counter medication and we check it for interactions with Forskolin Extract by Herbadiet — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Forskolin Extract by Herbadiet
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Herbadiet Forskolin Extract is a single-ingredient supplement: Coleus forskohlii extract powder. This plant extract contains forskolin, a compound that research has studied for several potential uses, though evidence remains limited.
There are no inactive or filler ingredients in this product.
Does it work?
Not established
The effectiveness data we hold for coleus shows insufficient reliable evidence to rate it for all the uses studied: angina, asthma, cancer, congestive heart failure, atopic dermatitis (eczema), and dry eye. That means the research is too thin or inconsistent right now to say whether it works for any of these.
If you're considering it for a specific health goal, talk it over with your doctor or pharmacist — they can help you weigh what limited evidence exists against other options.
How safe is it?
Well-documented data
Taken by mouth, coleus extract is generally well tolerated, but you should know about the side effects that have been reported. The most common are constipation, diarrhea, nausea, and vomiting — diarrhea appears most frequent, with loose stools reported in a small number of trial participants and about a 10% rate of gastrointestinal upset in retrospective reports.
Because coleus may lower blood pressure and isn't well studied long-term, use it only with professional guidance. The safety data advises against use during pregnancy and breastfeeding — not enough information exists to know it's safe for you or your baby.
Meds to double-check
Major interaction found
Before taking Herbadiet Forskolin Extract, double-check with your doctor or pharmacist if you take nitrates or calcium channel blockers for chest pain or high blood pressure (Major severity). Also confirm it's safe if you're on blood pressure medications, blood thinners or antiplatelet drugs like aspirin, or warfarin — all carry Moderate risk.
If you take other medications processed by your liver, those need checking too, since coleus may change how they work.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
This is a single-ingredient extract with limited evidence of effectiveness and several serious potential interactions with heart, blood pressure, and blood-thinning medications. If you take any prescription drugs — especially for your cardiovascular system or bleeding prevention — check with your doctor or pharmacist before starting.
Even if you don't take medications, the lack of long-term safety data and its blood-pressure-lowering effects mean you should talk it over with your own healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Forskolin Extract, straight from the product label.
| Brand | Herbadiet |
|---|---|
| Net contents | 0 Not Present |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 244348 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Forskolin Extract by Herbadiet, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coleus forskohlii extract powder | 10 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Weight management
Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast
V vegan
Ethically sourced Scientifically tested Premium grade ingredients
Formula
Standardized extract powder derived from Coleus forskohlii roots
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement take up to 20 mg, or as directed by your physician
Precautions
Keep out of reach of children.
Pregnant or lactating women should consult your physician before use.
Storage
Store in a dry, cool & dark.
FDA Disclaimer Statement
Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Batch No. ARK-P88
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Forskolin Extract by Herbadiet label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Forskolin Extract by Herbadiet
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size10 mg Dosage formPowder Amounts shown are per serving.
Coleus forskohlii extract powder
Interacts with915 drugs
Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. Whil...
Coleus forskohlii extract powder monograph & interactionsForskolin Extract by Herbadiet Drug Interactions
HelloPharmacist Interaction Report
Herbadiet Forskolin Extract, which contains Coleus forskohlii extract powder, interacts with several important medication types.
The most serious concerns are with nitrates and calcium channel blockers (heart and blood pressure medications), both rated Major — coleus can add to their blood-vessel-relaxing effects in ways we can't fully predict.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions affect blood pressure drugs generally, blood thinners (anticoagulants and antiplatelets like aspirin), and warfarin specifically. Coleus may lower your blood pressure further, raising the risk of dizziness or fainting, and may increase bleeding risk.
It also may interfere with how your body processes warfarin, making it harder or easier to work — which is dangerous either way.
Additionally, coleus may affect how your liver breaks down a broad range of other drugs through two enzyme pathways (CYP2C9 and CYP3A4 substrates), potentially increasing side effects or reducing how well those medications work. Altogether, these interactions span 916 individual medications.
Before you start this product, run your exact medications through the interaction checker below — especially anything for your heart, blood pressure, or blood clotting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Forskolin Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Forskolin Extract interact with 915 drugs. Click any drug to see the details.
1 of the 1 ingredient in Forskolin Extract interact with drugs. Each result below shows which ingredient is responsible. Coleus forskohlii extract powder
AvacopanTavneos
How Avacopan interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Avacopan interactionAvanafilStendra
How Avanafil interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Avanafil interactionAvapritinibAyvakit
How Avapritinib interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Avapritinib interactionAxitinibInlyta
How Axitinib interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Axitinib interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Read the full Coleus Forskohlii Extract Powder + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Azilsartan, Chlorthalidone interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Beclomethasone Dipropionate interactionBedaquilineSirturo
How Bedaquiline interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Bedaquiline interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Belumosudil Mesylate interactionBenazeprilLotensin
How Benazepril interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Benzhydrocodone, Acetaminophen interactionBenzthiazideExna
How Benzthiazide interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Coleus Forskohlii Extract Powder + Betaxolol interactionBetrixabanBevyxxa
How Betrixaban interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
Read the full Coleus Forskohlii Extract Powder + Betrixaban interactionBexaroteneTargretin
How Bexarotene interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with Forskolin Extract — through 1 ingredient. Tap an ingredient for the detail:
Coleus Forskohlii Extract PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Coleus Forskohlii Extract Powder + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Forskolin Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coleus forskohlii extract powder
Calcium Channel Blockers
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.
Nitrates
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.
Antihypertensive Drugs
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.
Warfarin (Coumadin)
Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.
Brand information
Manufacturer and brand details for Forskolin Extract, from the product label.
Herbadiet
See all Herbadiet products- Name
- Arkure Health Care
- Street Address
- 11, Sector - 14
- City
- Rohtak
- State
- Haryana
- ZipCode
- 124001
- Web Address
- www.herbadiet.in
Forskolin Extract by Herbadiet: Common Questions
Does Forskolin Extract by Herbadiet interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does this product actually do?
What side effects should I watch for?
Is this safe to use while pregnant or breastfeeding?
Can I take this with my blood pressure medication?
Does it have fillers or other ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Forskolin Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Forskolin Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Forskolin Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coleus 16 references
- Baumann G, Felix S, Sattelberger U, Klein G. Cardiovascular effects of forskolin (HL-362) in patients with idiopathic congestiv cardiomyopathy. A comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 1990;16:93-100.
- Kramer W, Thormann J, Kindler M, Schlepper M. Effects of forskolin on left ventricular function in dilated cardiomyopathy. Arzneimittelforschung 1987;37:364-7.
- Bauer K, Dietersdorfer F, Kaspar S, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;53:76-83. PubMed
- Christenson JT, Thulesius O, Nazzal MM. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Vasa 1995;24:56-61.
- Agarwal KC, Zielinski BA, Maitra RS. Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep. Thromb Haemost 1989;61:106-10. DOI
- Agarwal KC, Parks RE. Forskolin: a potential antimetastatic agent. Int J Cancer 1983;32:801-4. PubMed
- Almeida, F. C. and Lemonica, I. P. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1-2):53-60. PubMed
- Ding, X. and Staudinger, J. L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 2005;312(2):849-856. PubMed
- Staudinger, J. L., Ding, X., and Lichti, K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert.Opin Drug Metab Toxicol 2006;2(6):847-857. PubMed
- van Hecke, E., Hindryckx, P., Geuns, J. M., and Devriese, E. Airborne contact dermatitis from coleus in a housewife. Contact Dermatitis 1991;25(2):128-129. PubMed
- Schlepper, M., Thormann, J., and Mitrovic, V. Cardiovascular effects of forskolin and phosphodiesterase-III inhibitors. Basic Res Cardiol 1989;84 Suppl 1:197-212. PubMed
- Dooms-Goossens, A., Borghijs, A., Degreef, H., Devriese, E. G., and Geuns, J. M. Airborne contact dermatitis to Coleus. Contact Dermatitis 1987;17(2):109-110. PubMed
- Lindner, E., Dohadwalla, A. N., and Bhattacharya, B. K. Positive inotropic and blood pressure lowering activity of a diterpene derivative isolated from Coleus forskohli: Forskolin. Arzneimittelforschung 1978;28(2):284-289.
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