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Dietary supplement

Full Spectrum Spinach Leaf 400 mg Ingredients & Drug Interactions

by Swanson Premium Brand

Full Spectrum Spinach Leaf 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Full Spectrum Spinach Leaf 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Full Spectrum Spinach Leaf 400 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, eye health, heart health and blood pressure.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Spinach. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand

Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: spinach leaf, 400 mg per capsule. It's a whole-food extract — the leafy green vegetable you'd eat, concentrated into capsule form.

The capsules also hold hypromellose, an inactive ingredient that forms the capsule shell.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Spinach product and its label doesn't state a use — see Spinach's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence in our data to rate spinach leaf for nonalcoholic fatty liver disease, cognitive function, muscle strength, obesity, or polycystic ovary syndrome. The evidence available isn't strong enough to say whether it works for any of these uses.

The evidence, ingredient by ingredient Spinach

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Spinach is safe and well tolerated as a food for most people. It's considered safe during pregnancy and while breastfeeding.

The only serious rare adverse effect reported is methemoglobinemia in infants under 4 months old — so if you have a newborn, this is something to know. Allergic reactions are possible in people sensitive to spinach, and occupational asthma and lung inflammation have been reported from inhaling spinach powder, though that's not a concern with capsules.

Side effects, ingredient by ingredient Spinach

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Spinach.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on warfarin (or any blood thinner) — vitamin K in spinach interferes with how these drugs work and may require dose adjustment. Also flag it if you take diabetes medications, since spinach may lower blood sugar and increase hypoglycemia risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is straightforward spinach in a capsule — useful if you're not getting enough leafy greens in your diet, but only if you're not on warfarin or diabetes medications without talking to your doctor first. If you do take blood thinners or blood sugar drugs, check with your own pharmacist or doctor before starting this product, since consistent vitamin K intake matters for warfarin dosing and spinach can lower blood sugar.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Spinach Leaf 400 mg, straight from the product label.

Brand Swanson Premium Brand
Barcode (UPC) 087614114026
Net contents 90 Veggie Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2019
DSLD ID 206341
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614114026
IngredientAmount% DV
Spinach400 mg--

Other ingredients: Hypromellose, May contain one or more of the following

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bringing wellness to the world since 1969

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

V Vegetarian formula

Formulation

V Vegetarian formula

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule one to three times per day with water.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Full Spectrum Spinach Leaf 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Spinach

Interacts with
88 drugs
400 mg per serving

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...

Spinach monograph & interactions

Other (inactive) ingredients: Hypromellose, May contain one or more of the following. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand Drug Interactions

Want to check YOUR meds against Full Spectrum Spinach Leaf 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Moderate

Ingredients driving the most interactions

Spinach 88

Individual Drug Interactions

The ingredients in Full Spectrum Spinach Leaf 400 mg interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Full Spectrum Spinach Leaf 400 mg interact with drugs. Each result below shows which ingredient is responsible. Spinach

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Spinach Leaf 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Spinach2 drug types · 88 drugs

Antidiabetes Drugs

There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.

Likelihood Possible Evidence D
Spinach full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Full Spectrum Spinach Leaf 400 mg, from the product label.

Swanson Premium Brand

See all Swanson Premium Brand products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand: Common Questions

Does Full Spectrum Spinach Leaf 400 mg by Swanson Premium Brand interact with any medications?
Yes. Based on its ingredients, Full Spectrum Spinach Leaf 400 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Spinach Leaf 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is spinach safe to take while I'm pregnant or breastfeeding?
Yes — spinach as a food is considered safe during pregnancy and while breastfeeding, and it provides folate, which is helpful in pregnancy. This product delivers spinach in capsule form, so the same safety applies.
Can spinach help with weight loss or PCOS?
We don't have reliable evidence in our data to say whether spinach leaf works for weight loss or polycystic ovary syndrome. The research available isn't strong enough to rate it for either condition.
Are there any side effects I should expect?
Spinach is well tolerated when consumed as a food. Allergic reactions are possible in people sensitive to spinach. Serious side effects are very rare, except in infants under 4 months old, where a blood condition called methemoglobinemia has been reported.
What's in the capsule besides spinach?
The capsule shell is made from hypromellose, an inactive ingredient. There are no fillers or other active ingredients — just spinach.
I'm on warfarin. Can I take this?
Not without checking with your doctor first. Spinach contains vitamin K, which interferes with warfarin's blood-thinning effect, and taking it daily for a week can throw off your warfarin dose. Your doctor may need to adjust your medication or advise against consistent use of this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Spinach Leaf 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Spinach Leaf 400 mg label
Go deeper

The Full Monographs Behind Full Spectrum Spinach Leaf 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Spinach

Interacts with 88 drugs

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is very safe as a food, concentrated supple...

Read the full Spinach monograph →
Sources

Sources & How We Checked

Full Spectrum Spinach Leaf 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Spinach 6 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
  4. Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
  5. Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
  6. Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.

See these in context on the Spinach monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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