Full Spectrum Stinging Nettle 420 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Full Spectrum Stinging Nettle 420 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Full Spectrum Stinging Nettle 420 mg is a dietary supplement by Planetary Herbals with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,053 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Nettle leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Full Spectrum Stinging Nettle 420 mg by Planetary Herbals
Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum Stinging Nettle 420 mg by Planetary Herbals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Full Spectrum Stinging Nettle 420 mg by Planetary Herbals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients, both forms of stinging nettle: nettle leaf extract and nettle. Together they make up the 420 mg dose per tablet.
The product also includes inactive ingredients like microcrystalline cellulose, calcium phosphate, and silica — common tablet fillers and binders.
Does it work?
Not established
Stinging nettle is possibly effective for diabetes; clinical research suggests it may help lower blood sugar levels. For allergic rhinitis (hay fever), anemia, asthma, benign prostatic hyperplasia (enlarged prostate), and gingivitis, the evidence isn't established enough in our data to rate it.
How safe is it?
Well-documented data
Taken by mouth as directed, stinging nettle is generally well tolerated, though the quality and strength of products vary. The most common side effects are constipation and diarrhea.
Very rare case reports describe liver injury, though those involved combination herbal products with multiple ingredients — it's not clear stinging nettle alone was the cause. If you touch the raw plant, you may get localized itching, rash, or stinging.
Pregnancy: there isn't enough safety data, and traditional concerns about effects on the uterus mean it's best to avoid it. Breastfeeding: safety hasn't been established; talk with your doctor before use.
Meds to double-check
Moderate interaction found
Before you start, double-check if you take blood thinners like warfarin, diabetes medications (drugs that lower blood sugar), diuretics (water pills), or lithium. Altogether, these interactions span 163 individual medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood thinners, diabetes drugs, diuretics, or lithium, check with your pharmacist before starting this. For others interested in nettle for possible blood sugar support, it's generally well tolerated when taken as directed — but verify your exact medications first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Full Spectrum Stinging Nettle 420 mg, straight from the product label.
| Brand | Planetary Herbals |
|---|---|
| Barcode (UPC) | 021078104773 |
| Net contents | 120 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 322761 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Full Spectrum Stinging Nettle 420 mg by Planetary Herbals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 4% |
| Nettle leaf extract | 210 mg | -- |
| Nettle | 210 mg | -- |
Other ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Stearic Acid, Modified Cellulose Gum, Silica, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
For healthy sinus support
FDA Statement of Identity
Herbal Supplement
General Statements
Approved by Michael Tierra L.Ac, O.M.D Michael Tierra
Suggested/Recommended/Usage/Directions
Suggested use: 1 tablet twice daily between meals.
Formula
Stinging Nettle is one of the most important tonics of western herbal traditions and was traditionally used to support healthy sinuses. Modern research documents this use in biological assays demonstrating it reduces the biosynthesis of arachidonic acid and leukotrienes that play key roles in healthy immune responses and sinus health.
Storage
Store in a cool, dry place.
Precautions
Note: if you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Copyright Planetary Herbals, LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Full Spectrum Stinging Nettle 420 mg by Planetary Herbals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Full Spectrum Stinging Nettle 420 mg by Planetary Herbals
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsNettle leaf extract
Interacts with164 drugs
Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...
Nettle leaf extract monograph & interactionsNettle
Interacts with164 drugs
Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...
Nettle monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Stearic Acid, Modified Cellulose Gum, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Full Spectrum Stinging Nettle 420 mg by Planetary Herbals Drug Interactions
HelloPharmacist Interaction Report
Planetary Herbals' Full Spectrum Stinging Nettle can interact with several medication types.
The main concern is with blood thinners like warfarin (Coumadin): stinging nettle is high in vitamin K, which can reduce how well blood thinners work if you take large amounts of the supplement.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take diabetes medications (drugs that lower blood sugar) or diuretics (water pills). Stinging nettle may add to their effects — meaning your blood sugar could drop lower than intended, or the diuretic effect could be stronger.
If you take lithium for mood disorders, stinging nettle might reduce how your body clears it, potentially raising lithium levels in your blood.
Additionally, if none of those apply to you, no other major interaction categories are documented for the ingredients we could check. Run your exact medications through the search tool on this page to be sure.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Full Spectrum Stinging Nettle 420 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Full Spectrum Stinging Nettle 420 mg interact with 2,053 drugs. Click any drug to see the details.
2 of the 3 ingredients in Full Spectrum Stinging Nettle 420 mg interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Nettle leaf extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Acetaminophen, Caffeine, Pyrilamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Acetaminophen, Pamabrom, Pyrilamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Acetazolamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Acetohexamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Full Spectrum Stinging Nettle 420 mg — through 1 ingredient. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Alogliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Alogliptin, Metformin interactionNettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Alogliptin, Pioglitazone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Pioglitazone interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Amiloride, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Ammonium Chloride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ammonium Chloride interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Atenolol, Chlortalidone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Atenolol, Chlorthalidone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Azilsartan, Chlorthalidone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Benazepril, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bendroflumethiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bendroflumethiazide, Nadolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bendroflumethiazide, Potassium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bendroflumethiazide, Rauwolfia Serpentina interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Benzthiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benzthiazide interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bisoprolol, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bumetanide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Bumetanide, Potassium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Caffeine, Potassium Salicylate, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Caffeine, Potassium Salicylate, Salicylamide interactionCanagliflozinInvokana
How Canagliflozin interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Canagliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionNettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionNettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Nettle + Canagliflozin, Metformin Hydrochloride interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Candesartan Cilexetil, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Full Spectrum Stinging Nettle 420 mg — through 2 ingredients. Tap an ingredient for the detail:
NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Nettle + Captopril, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Captopril, Hydrochlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Full Spectrum Stinging Nettle 420 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Nettle leaf extract
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Brand information
Manufacturer and brand details for Full Spectrum Stinging Nettle 420 mg, from the product label.
Planetary Herbals
See all Planetary Herbals products- Name
- Planetary Herbals, LLC
- Street Address
- P.O. Box 1760
- City
- Soquel
- State
- CA
- ZipCode
- 95073
- Web Address
- www.planetaryherbals.com
Full Spectrum Stinging Nettle 420 mg by Planetary Herbals: Common Questions
Does Full Spectrum Stinging Nettle 420 mg by Planetary Herbals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while pregnant?
Is it safe while breastfeeding?
What side effects might I get?
Does stinging nettle actually work for anything?
Why is there vitamin K in this if I take a blood thinner?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Full Spectrum Stinging Nettle 420 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Full Spectrum Stinging Nettle 420 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph →Sources & How We Checked
Full Spectrum Stinging Nettle 420 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Stinging Nettle 23 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
- Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
- Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
- Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
- Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
- Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
- Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
- Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
- Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
- Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
- Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
- Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
- Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
- Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
- Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
- Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
- Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC