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Dietary supplement

GABA Ingredients & Drug Interactions

by LiveLong

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

GABA is a dietary supplement by LiveLong with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma Amino Butyric Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of GABA by LiveLong

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

LiveLong GABA powder contains one active ingredient: gamma-aminobutyric acid (GABA), a natural brain chemical involved in relaxation and sleep. There are no other inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Promote calm, relaxation and natural sleep.
  • We looked for evidence on: Anxiety, Insomnia, Stress, Tension relief.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Post-traumatic stress disorder (PTSD).

The evidence for GABA isn't established in our data. The product has been studied for anxiety, ADHD, athletic performance, cerebral palsy, and chronic bronchitis, but the research doesn't support a clear claim for any of these uses — we don't hold enough reliable evidence to rate it one way or the other.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, GABA is generally well tolerated over short periods, though long-term safety hasn't been well studied. Common side effects when taken by mouth include drowsiness, stomach upset, mild throat burning, muscle weakness, and nausea.

One case reported a temporary loss of menstrual periods in someone taking GABA with another supplement. The safety data is limited, so it's best not to take it during breastfeeding unless your doctor says otherwise.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any blood pressure medications (antihypertensives), double-check before starting — GABA can lower your pressure further. Also flag any sedating medications (sleep aids, anti-anxiety drugs, pain relievers with sedative effects) with your pharmacist, since GABA might add to that drowsy effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA may appeal to you if you're curious about relaxation supplements and don't take blood pressure drugs or sedating medications. If you're on either of those types, check with your pharmacist first — the interaction risk is real.

Long-term use hasn't been well studied, so this is best discussed with your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA, straight from the product label.

Brand LiveLong
Barcode (UPC) 609728346256
Net contents 100 g
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21742
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA by LiveLong, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 tsp
Maximum serving Sizes:
0.5 tsp
Servings per container
100
UPC/BARCODE
609728346256
IngredientAmount% DV
Gamma Amino Butyric Acid1 g--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

GABA is an abbreviation for Gamma Amino Butyric Acid, the neutotransmitter used to inhibit electrical impulses in nerves, leading to inner calm and relaxed muscle. GABA is often used toto facilitate sleep and has been scientifically demonstrated to show an increase in the amount of Growth Hormone produced by the brain. The beneficial effects of GABA are far reaching and profound. Users often report a subtle tingling sensation that may be uncomfortable so begin with a low dose and work up to the recommended dosage.

- Facilitates Natural Sleep - Increases Growth Hormone - Decreases TensIon

BULK POWDER

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1-2 servings daily. Always consult your physician before taking supplements.

Precautions

WARNING: KEEP OUT OF REACH OF CHILDREN.

Consult your physician before using this dietary supplement. Do not use this product if you are at risk or are being treated for high blood pressure, heart, kidney, thyroid, or psychiatric disease, difficulty in urinating, prostate enlargement, anxiety, depression, seizure disorder, or stroke.

Consult your healthcare professional before use if you are taking antidepressants, MAO Inhibitors, or any other prescription drugs.

Discontinue use and consult your healthcare professional if dizziness, sleeplessness, tremors, nervousness, headache or heart palpitations occur. Consult your healthcare practitioner before beginning any weight loss program.

See for yourself

GABA by LiveLong label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in GABA by LiveLong

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 tsp Dosage formPowder Servings per container100 Amounts shown are per serving.

Gamma Amino Butyric Acid

Interacts with
419 drugs
1 g per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma Amino Butyric Acid monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA by LiveLong Drug Interactions

Want to check YOUR meds against GABA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gamma Amino Butyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for GABA, from the product label.

LiveLong

See all LiveLong products
Name
LIVELONG NUTRITION(TM)
City
Piedmont
State
SC
ZipCode
29673
Web Address
www.LiveLongSupplements.com
Pharmacist Counseling Corner

GABA by LiveLong: Common Questions

Does GABA by LiveLong interact with any medications?
Yes. Based on its ingredients, GABA has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does GABA actually work for anxiety?
The research we have doesn't give us enough reliable evidence to say one way or the other. It's been studied for anxiety, but we can't make a solid claim about whether it works.
What are the most common side effects?
When taken by mouth, drowsiness, stomach upset, sore throat, muscle weakness, and nausea have been reported. Most people tolerate it okay in the short term, but long-term safety isn't well established.
Is it safe to take if I'm pregnant or breastfeeding?
There isn't enough safety information to know either way during pregnancy. During breastfeeding, the data advises against it unless your doctor says otherwise. Talk with your doctor or pharmacist about your specific situation.
How much GABA is in this powder?
That information isn't included in our product facts, so you'll want to check the label or contact the manufacturer for the serving size and amount per scoop.
Can I take this long-term?
Long-term safety hasn't been well studied, so we don't have solid data on that. It's worth discussing with your doctor if you're thinking about taking it regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA label
Sources

Sources & How We Checked

GABA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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