Garcinia Body-Fat Reduction Diet Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Garcinia Body-Fat Reduction Diet against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Garcinia Body-Fat Reduction Diet is a dietary supplement by Applied Nutrition with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 704 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia (Garcinia cambogia) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Garcinia Body-Fat Reduction Diet by Applied Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Garcinia Body-Fat Reduction Diet by Applied Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Garcinia Body-Fat Reduction Diet by Applied Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Garcinia Body-Fat Reduction Diet contains one active ingredient: garcinia (Garcinia cambogia) extract, a tropical fruit extract whose main component is hydroxycitric acid. The product also includes inactive ingredients—microcrystalline cellulose, calcium phosphate, croscarmellose sodium, silicon dioxide, magnesium stearate, stearic acid, sodium carboxymethylcellulose, dextrose, soy lecithin, sodium citrate, and dextrin—which serve as binders, fillers, and capsule materials.
Does it work?
Not established
The evidence supporting garcinia for weight loss and related uses isn't established in our data. We hold insufficient reliable evidence to rate it for athletic performance, nonalcoholic fatty liver disease, hyperlipidemia, or obesity.
If you're considering this supplement to support any of those goals, talk with your doctor or pharmacist about what the current research really shows and whether it's right for your situation.
How safe is it?
Well-documented data
Garcinia is generally well tolerated short-term, though common side effects include diarrhea, gastrointestinal discomfort, headache, and nausea. Serious adverse effects are rare but documented—they include liver injury, liver failure, mania (which may be triggered in people with bipolar disorder), pancreatitis, and one case of severe heart inflammation.
There isn't enough safety data to use garcinia during pregnancy or while breastfeeding; the safety notes advise against it in both situations.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your own doctor or pharmacist if you take serotonergic drugs like antidepressants or migraine medications (moderate risk of serotonin syndrome), blood thinners or antiplatelet drugs (moderate bleeding risk), diabetes medications (moderate risk of low blood sugar), or any drug known to stress the liver (moderate risk of liver damage).
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Garcinia Body-Fat Reduction Diet is a single-ingredient supplement with four moderate-severity interactions involving serotonergic drugs, blood thinners, diabetes medications, and drugs that can damage the liver. Because of these risks and the rare but serious adverse effects on file, you should check your medications and talk with your doctor or pharmacist before starting it—especially if you take antidepressants, blood thinners, or diabetes drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Garcinia Body-Fat Reduction Diet, straight from the product label.
| Brand | Applied Nutrition |
|---|---|
| Barcode (UPC) | 710363582340 |
| Net contents | 40 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Aug 24, 2016 |
| DSLD ID | 64149 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Garcinia Body-Fat Reduction Diet by Applied Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia (Garcinia cambogia) extract | 1200 mg | -- |
Other ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Croscarmellose Sodium, Silicon Dioxide, Magnesium Stearate, Stearic Acid, Sodium Carboxymethylcellulose, Dextrose, Soy Lecithin, Sodium Citrate, Dextrin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Usage Warnings: Do not use if safety seal is broken.
Contains: Soy
Do not exceed recommended daily intake.
Not intended for use by persons under 18. Keep out of reach of children.
Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.
Check with your doctor before using this product if you are using medication or have any medical conditions, including digestive disorders. Do not use if you may become pregnant, are pregnant or nursing.
Suggested/Recommended/Usage/Directions
Do not exceed recommended daily intake.
Directions: (Adult) Take two (2) tablets in the morning and two (2) tablets int eh afternoon with food and a full glass of water.
Formula
Contains: Soy
Storage
Store in a cool, dry place.
General Statements
Diet & Exercise Plan available online at: www.AppliedNutrition.com/deplan
HCA (hydroxycitric acid) is a compound that targets fat production in the body. Emerging research demonstrates that HCA inhibits a portion of the body's citrate lyase (an enzyme responsible for coverting carbohydrates into fat).
Standardized pure extract
Targets fat production and carb conversion in the body.
Why are people talking about this amazing fruit? Garcinia is a small pumpkin-shaped fruit native to Indonesia. It supplies a unique compound called hydroxycitric acid (HCA) that targets fat production in the body. Emerging research demonstrates that HCA inhibits a portion of the body's citrate lyase (an enzyme responsible for converting carbohydrates into fat).
Brand IP Statement(s)
How Does Garcinia Work? Garcinia Body-Fat Reduction Diet delivers a concentrated garcinia extract that is standardized to 50% HCA.
When used in conjunction with a sensible diet and exercise plan, garcinia body-fat reduction diet can help support healthy weight management.
Applied Nutrition is committed to developing science-based products that exceed the highest standards for quality and purity. As a leader in innovation, we continuously strive to bring forward new ideas and groundbreaking formulas that enhance health and well-being. To view our entire line of products, please visit us online at:
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary supplement
General
7467-BOX-AN078234-V1-09/15
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Garcinia Body-Fat Reduction Diet by Applied Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Garcinia Body-Fat Reduction Diet by Applied Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container20 Amounts shown are per serving.
Garcinia (Garcinia cambogia) extract
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia (Garcinia cambogia) extract monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Dibasic Calcium Phosphate, Croscarmellose Sodium, Silicon Dioxide, Magnesium Stearate, Stearic Acid, Sodium Carboxymethylcellulose, Dextrose, Soy Lecithin, Sodium Citrate, Dextrin. These complete the product’s ingredient list but are not active constituents.
Garcinia Body-Fat Reduction Diet by Applied Nutrition Drug Interactions
HelloPharmacist Interaction Report
Garcinia Body-Fat Reduction Diet by Applied Nutrition, through its garcinia extract, interacts with several medication types.
The most serious concern is with serotonergic drugs (antidepressants, migraine medications, and others that affect serotonin)—combining them with garcinia carries a moderate risk of serotonin syndrome, a potentially dangerous condition marked by confusion, rapid heartbeat, muscle rigidity, and high fever. One documented case involved a patient on escitalopram who developed serotonin syndrome after taking garcinia extract.
Read the full breakdown — every affected drug type, severity by severity
Garcinia also poses moderate risks with blood thinners (anticoagulants and antiplatelet drugs), as its active ingredient may increase bleeding risk; with diabetes medications, where it might lower blood sugar further and raise the risk of low blood sugar (hypoglycemia); and with drugs that can harm the liver (hepatotoxic drugs), since garcinia itself has been linked to rare cases of liver injury and elevated liver enzymes.
Although garcinia is generally well tolerated short-term, the combination of these interaction risks means you should check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Garcinia Body-Fat Reduction Diet?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Garcinia Body-Fat Reduction Diet interact with 704 drugs. Click any drug to see the details.
1 of the 1 ingredient in Garcinia Body-Fat Reduction Diet interact with drugs. Each result below shows which ingredient is responsible. Garcinia (Garcinia cambogia) extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia (garcinia Cambogia) Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia (garcinia Cambogia) Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia (garcinia Cambogia) Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia (garcinia Cambogia) Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Garcinia Body-Fat Reduction Diet — through 1 ingredient. Tap an ingredient for the detail:
Garcinia (garcinia Cambogia) ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia (garcinia Cambogia) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Garcinia Body-Fat Reduction Diet with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia (Garcinia cambogia) extract
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for Garcinia Body-Fat Reduction Diet, from the product label.
Applied Nutrition
See all Applied Nutrition products- Name
- Applied Nutrition
- Street Address
- P.O. Box 66457
- City
- Los Angeles
- State
- CA
- ZipCode
- 90066
- Web Address
- www.AppliedNutrition.com
Garcinia Body-Fat Reduction Diet by Applied Nutrition: Common Questions
Does Garcinia Body-Fat Reduction Diet by Applied Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does garcinia extract actually do?
What are the most common side effects?
Can I take garcinia if I'm pregnant or breastfeeding?
Why is this interaction list so long?
Does garcinia work for weight loss?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Garcinia Body-Fat Reduction Diet is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Garcinia Body-Fat Reduction Diet’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Garcinia Body-Fat Reduction Diet's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
- Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia Cambogia in obese women. Phytother Res 2014;28(6):887-91.
- Marquez F, Babio N, Bullo M, Salas-Salvado J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Crit Rev Food Sci Nutr 2012;52:585-94.
- Allen SF, Godley RW, Evron JM, et al. Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids. Can J Cardiol 2014;30(12):1732 e13-1732 e15. PubMed
- Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol. 2008 Dec 7;14(45):6999-7004. PubMed
- Sharma T, Wong L, Tsai N, Wong RD. Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J. 2010 Aug;69(8):188-90.
- Rashid NN, Grant J. Hydroxycut hepatotoxicity. Med J Aust. 2010 Feb 1;192(3):173-4. PubMed
- Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. 2007 Oct;39(10):953-5. PubMed
- Corey R, Werner KT, Singer A, Moss A, Smith M, Noelting J, Rakela J. Acute liver failure associated with Garcinia cambogia use. Ann Hepatol. 2016 Jan-Feb;15(1):123-6. PubMed
- Melendez-Rosado J, Snipelisky D, Matcha G, Stancampiano F. Acute hepatitis induced by pure Garcinia cambogia. J Clin Gastroenterol. 2015 May-Jun;49(5):449-50. PubMed
- García-Cortés M, Robles-Díaz M, Ortega-Alonso A, Medina-Caliz I, Andrade RJ. Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int J Mol Sci. 2016 Apr 9;17(4):537. PubMed
- Dehoney S, Wellein M. Rhabdomyolysis associated with the nutritional supplement Hydroxycut. Am J Health Syst Pharm. 2009;66(2):142-8. PubMed
- Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561-6. PubMed
- Hendrickson BP, Shaikh N, Occhiogrosso M, Penzner JB. Mania Induced by Garcinia cambogia: A Case Series. Prim Care Companion CNS Disord. 2016;18(2).
- Kaswala D, Shah S, Patel N, Raisoni S, Swaminathan S. Hydroxycut-induced Liver Toxicity. Ann Med Health Sci Res. 2014; 4(1):143-5. PubMed
- Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol. 2009;15(14):1786-7. PubMed
- Lunsford KE, Bodzin AS, Reino DC, Wang HL, Busuttil RW. Dangerous dietary supplements: Garcinia cambogia -associated hepatic failure requiring transplantation. World J Gastroenterol. 2016;22(45):10071-10076.
- Narasimha A, Shetty PH, Nanjundaswamy MH, Viswanath B, Bada Math S. Hydroxycut - Dietary supplements for weight loss: Can they induce mania? Aust N Z J Psychiatry. 2013;47(12):1205-6. PubMed
- Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. 2009;54(2):406-8. PubMed
- Stohs SJ, Preuss HG, Ohia SE, et al. No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol. 2009;15(32):4087-9. PubMed
- Gavril A, Ribnikar M, Smid L, Luzar B, Stabuc B. Fat burner-induced acute liver injury: case series of four patients. Nutrition. 2018;47:110-114. doi: 10.1016/j.nut.2017.10.002. PubMed
- Bystrak T, Cervera-Hernandez ME, Reddy N, King Z, Bratberg J. Garcinia cambogia, diabetic ketoacidosis, and pancreatitis. R I Med J (2013). 2017 Oct 2;100(10):48-50. NO DOI
- Smith RJ, Bertilone C, Robertson AG. Fulminant liver failure and transplantation after use of dietary supplements. Med J Aust. 2016;204(1):30-2. PubMed
- Nguyen DC, Timmer TK, Davison BC, McGrane IR. Possible Garcinia cambogia-induced mania with psychosis: a case report. J Pharm Pract 2019;32(1):99-102. doi: 10.1177/0897190017734728.
- Yousaf MN, Chaudhary FS, Hodanazari SM, Sittambalam CD. Hepatotoxicity associated with Garcinia cambogia: a case report. World J Hepatol 2019;11(11):735-42.
- Mas Ordeig A, Bordón García N. Hepatotoxicity caused by Garcinia cambogia. Gastroenterol Hepatol 2020;43(3):134-5. DOI
- Cho HK, Han YS, Park JM. Ocular complications of Garcinia cambogia extract diet pills: case report. Eur J Ophthalmol 2019:1120672119872364. PubMed
- Ferreira V, Mathieu A, Soucy G, Giard JM, Erard-Poinsot D. Acute severe liver injury related to long-term Garcinia cambogia intake. ACG Case Rep J. 2020;7(8):e00429. PubMed
- Iqbal U, Anwar H, Siddiqui HU, Mehmood A. Acute Pancreatitis Secondary to Use of Appetite Suppressant: Garcinia cambogia. Cureus. 2019;11(5):e4676. PubMed
- Grigos A, Benmoussa J, Sandhu J, Chaucer B, Clarke M, SH Patel. Acute pancreatitis secondary to Garcinia cambogia; the unknown cost of herbal supplements. JOP. J Pancreas (Online) 2016; 17(3):316-317.
- Sidhu RLS, Labana S, Khehra L. Garcinia cambogia: a link between the "miracle" weight loss pill and acute pancreatitis. Am J Gastroenterol. 2016. 111:S560-S561. DOI
- Vuppalanchi R, Bonkovsky HL, Ahmad J, et al. Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol 2021. PubMed
- Calaquian LL, Yau I. Garcinia cambogia-A Supplement-Related Liver Injury. Cureus 2022;14(2):e22225. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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