Garcinia Cambogia 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Garcinia Cambogia 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Garcinia Cambogia 500 mg is a dietary supplement by Dr. Rico Perez with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 704 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Garcinia Cambogia 500 mg by Dr. Rico Perez
Ask about any prescription or over-the-counter medication and we check it for interactions with Garcinia Cambogia 500 mg by Dr. Rico Perez — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Garcinia Cambogia 500 mg by Dr. Rico Perez
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: garcinia cambogia at 500 mg per capsule. Garcinia is a tropical fruit extract, and the form used here is standardized for hydroxycitric acid (HCA), its main compound.
The capsule itself is made from gelatin and filled with inactive ingredients including microcrystalline cellulose, starch, silicon dioxide, and magnesium stearate—these are standard binders and flow agents.
Does it work?
Not established
The evidence for garcinia cambogia's effectiveness isn't well established in the data we hold. For athletic performance, nonalcoholic fatty liver disease, hyperlipidemia (high cholesterol), and obesity, the rating is insufficient reliable evidence.
That means either the studies aren't strong enough or there aren't enough of them to say whether it actually works for these purposes.
How safe is it?
Well-documented data
Garcinia is generally well tolerated over the short term, and side effects in clinical research are usually mild—diarrhea, stomach discomfort, headache, and nausea show up occasionally. However, rare but serious adverse effects have been reported, including liver injury, liver failure, mania (especially in people with bipolar disorder), pancreatitis, and in one case, a severe heart inflammation that required emergency heart-lung support.
The safety data advises against use during pregnancy and while breastfeeding—there isn't enough evidence to know it's safe in those situations.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you're on blood thinners (like warfarin or aspirin), serotonergic antidepressants (like sertraline or escitalopram), drugs that can harm your liver, or diabetes medications. All carry Moderate interaction risk with garcinia.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you don't take blood thinners, antidepressants, blood sugar medication, or drugs that stress your liver, garcinia may be worth a trial. But because of the rare risk of liver injury and mania, and the moderate interaction risks with common medications, run your prescription list through the checker before starting.
Talk to your pharmacist or doctor if you have bipolar disorder, liver disease, or take anything regularly.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Garcinia Cambogia 500 mg, straight from the product label.
| Brand | Dr. Rico Perez |
|---|---|
| Barcode (UPC) | 879840000682 |
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 321012 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Garcinia Cambogia 500 mg by Dr. Rico Perez, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia cambogia | 500 mg | -- |
Other ingredients: Gelatin, Microcrystalline Cellulose, Starch, Silicon Dioxide, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one (1) capsule daily with any meal or as directed by your healthcare provider. Do not exceed recommended dosage. Individual results may vary.
Precautions
Do not exceed recommended dosage
Warning: Consult healthcare provider prior to use if: pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur. Do not use if product appears to be tampered with or seal is broken.
Keep out of reach of children.
Storage
Store at room temperature.
Formulation
Unconditionally guaranteed for purity, freshness and label potency. Manufactured in a cGMP certified facility. Freshness Assured
No added sugar, yeast, preservatives, artificial colors or flavors.
Seals/Symbols
Made in USA form domestic and foreign materials
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Garcinia Cambogia 500 mg by Dr. Rico Perez label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Garcinia Cambogia 500 mg by Dr. Rico Perez
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Garcinia cambogia
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia cambogia monograph & interactionsOther (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Starch, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Garcinia Cambogia 500 mg by Dr. Rico Perez Drug Interactions
HelloPharmacist Interaction Report
Garcinia Cambogia 500 mg by Dr.
Rico Perez does interact with several medication types, and the most serious concern is with blood thinners (anticoagulant and antiplatelet drugs). The active ingredient, hydroxycitric acid, may slow blood clotting in the lab, which could raise your bleeding risk if you're on warfarin, aspirin, or similar drugs.
Read the full breakdown — every affected drug type, severity by severity
Serotonergic drugs—mainly antidepressants like SSRIs—carry a Moderate risk of serotonin syndrome (agitation, confusion, rapid heart rate). One patient taking escitalopram reported serotonin syndrome after adding garcinia.
Drugs that stress your liver also pose a Moderate concern; garcinia itself has rare reports of liver injury, and combining it with other hepatotoxic medications could worsen that risk. Blood sugar medications (antidiabetes drugs) may have an additive effect, theoretically raising the risk of low blood sugar (hypoglycemia).
Additionally, no other ingredient interactions were identified because garcinia is the only active ingredient in this product. Altogether, these interactions span 687 individual medications.
Before you start, use the medication checker on this page to look up your exact prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Garcinia Cambogia 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Garcinia Cambogia 500 mg interact with 704 drugs. Click any drug to see the details.
1 of the 1 ingredient in Garcinia Cambogia 500 mg interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Abciximab interactionAbiraterone
How Abiraterone interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia Cambogia + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Garcinia Cambogia 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Garcinia Cambogia 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia cambogia
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for Garcinia Cambogia 500 mg, from the product label.
Dr. Rico Perez
See all Dr. Rico Perez products- Name
- Rico-Perez Products, Inc.
- Street Address
- 2295 Coral Way
- City
- Miami
- State
- FL
- ZipCode
- 33145
- Phone Number
- (800) 633-6799
- Web Address
- www.ricoperez.com
Garcinia Cambogia 500 mg by Dr. Rico Perez: Common Questions
Does Garcinia Cambogia 500 mg by Dr. Rico Perez interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does garcinia cambogia actually help with weight loss?
What are the most common side effects?
Can I take garcinia if I have bipolar disorder?
Is garcinia safe during pregnancy or breastfeeding?
Why does this product interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Garcinia Cambogia 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Garcinia Cambogia 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Garcinia Cambogia 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
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