Garcinia Cambogia Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Garcinia Cambogia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Garcinia Cambogia is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 704 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Garcinia Cambogia by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Garcinia Cambogia by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Garcinia Cambogia by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Herbal Hills Garcinia Cambogia contains one active ingredient: a blend of Garcinia cambogia fruit extract and fruit powder. The extract form concentrates hydroxycitric acid (HCA), garcinia's main active compound, which the ingredient is standardized to deliver.
The capsules also contain inactive ingredients—silicon dioxide, maize starch, and the HPMC capsule shell itself—which are fillers and binders that help hold the product together.
Does it work?
Couldn't assess
The evidence for garcinia in our data is thin. We hold no reliable evidence to rate it for weight loss (obesity), athletic performance, high cholesterol (hyperlipidemia), or nonalcoholic fatty liver disease (NAFLD).
That doesn't mean it doesn't work—it means the studies we have access to aren't solid enough to say.
How safe is it?
Well-documented data
Garcinia is generally well tolerated in the short term, but caution is warranted. The most common side effects in studies have been diarrhea, stomach upset, headache, and nausea.
Rare but serious adverse effects include liver injury and failure, as well as isolated reports of mania (racing thoughts, decreased need for sleep, risky behavior) and, in one case, a severe heart inflammation that required emergency life support. Do not use this product during pregnancy or while breastfeeding—there isn't enough safety data to know either way.
Talk with your doctor or pharmacist before using garcinia if you're pregnant, nursing, or planning to become pregnant.
Meds to double-check
Moderate interaction found
Before taking Herbal Hills Garcinia Cambogia, double-check with your doctor or pharmacist if you're on any serotonergic drugs like antidepressants (Moderate risk of serotonin syndrome), blood thinners (Moderate risk of increased bleeding), diabetes medications (Moderate risk of low blood sugar), or drugs that can stress the liver. No interactions are documented in our data beyond these categories, but the interaction list is long—run your full medication list through the checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Garcinia Cambogia may be worth considering if you're curious about weight management and have no liver disease, heart condition, or psychiatric history—but the evidence for its effectiveness isn't solid. If you take any antidepressant, blood thinner, diabetes medication, or drug that affects your liver, you need to check with your doctor or pharmacist before starting.
Rare serious side effects and a long interaction list mean this one warrants a conversation with your own healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Garcinia Cambogia, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906068411531 |
| Net contents | 700 Vegi Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2017 |
| DSLD ID | 75050 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Garcinia Cambogia by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend | 400 mg | -- |
Other ingredients: Silicon Dioxide, Maize Starch, HPMC Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
General Statements
Mfg. Lic. No. : PD/AYU/002/10
(An ISO 22000:2005 Certified Company)
Back to nature
Slimming aid
~ Pure ~ Natural ~ Effective
It is considered to improve fat metabolism and help enhance development of lean muscle mass.
Contents based on standard raw material as per ayurvedic text
Brand IP Statement(s)
Product name: Garciniahills
Seals/Symbols
JAS-ANZ ICS ISO 22000:2005 Reg. No.: RH91/7301
GMP Good Manufacturing Practice
Halal India www.halalindia.com
Storage
Store in a cool dry place away from direct sunlight.
Precautions
Keep out of reach of children.
Do not use if inner seal is broken or missing.
Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.
Formula
Standardized extract / 28% HCA
Garcinia contains hydroxycitric acid which is said to aid weight management.
Suggested/Recommended/Usage/Directions
Directions For Use: As a dietary supplement take 1 capsule twice daily, preferably after meals. For better results it should be taken with warm water
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Garcinia Cambogia by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Garcinia Cambogia by Herbal Hills
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend monograph & interactionsOther (inactive) ingredients: Silicon Dioxide, Maize Starch, HPMC Capsule. These complete the product’s ingredient list but are not active constituents.
Garcinia Cambogia by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Herbal Hills Garcinia Cambogia has documented interactions with several medication types.
The most serious concern involves serotonergic drugs (antidepressants and related medications), where there's a Moderate risk of serotonin syndrome — increased agitation, confusion, rapid heartbeat, and other serious symptoms. One patient on escitalopram developed this syndrome after adding garcinia extract.
Read the full breakdown — every affected drug type, severity by severity
The ingredient also carries Moderate interactions with blood thinners (anticoagulant and antiplatelet drugs), where garcinia's active compound may increase bleeding risk; drugs that treat high cholesterol or liver disease; and diabetes medications, where garcinia might lower blood sugar further and raise the risk of dangerously low blood sugar (hypoglycemia). Additionally, garcinia has been linked to rare but serious liver injury, so combining it with other drugs that stress the liver adds theoretical risk.
Altogether, these interactions span 705 individual medications. Before you start this product, run your exact medications through the checker on this page, and let your doctor or pharmacist know you're considering it—especially if you take an antidepressant, blood thinner, diabetes drug, or anything for your liver or cholesterol.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Garcinia Cambogia?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Garcinia Cambogia interact with 704 drugs. Click any drug to see the details.
1 of the 1 ingredient in Garcinia Cambogia interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abciximab interactionAbiraterone
How Abiraterone interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Garcinia Cambogia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder BlendSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Extract & Garcinia Cambogia Fruit Powder Blend + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Garcinia Cambogia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia cambogia fruit extract & Garcinia cambogia fruit powder blend
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for Garcinia Cambogia, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd.
- Street Address
- 55-A/B, Lonavala Co-op. Indl. Est. Ltd.
- City
- Nangargaon, Lonavala, Taluka-Maval, Dist. Pune,
- State
- Maharashtra
- ZipCode
- 410401
- Web Address
- 0091 22 2868 6868
Garcinia Cambogia by Herbal Hills: Common Questions
Does Garcinia Cambogia by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help me lose weight?
What are the most common side effects?
Can I take this if I'm pregnant or nursing?
Is this safe to take with my antidepressant?
What is hydroxycitric acid, and why is it in garcinia?
Can I take this with my blood thinner?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Garcinia Cambogia is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Garcinia Cambogia’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Garcinia Cambogia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
- Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia Cambogia in obese women. Phytother Res 2014;28(6):887-91.
- Marquez F, Babio N, Bullo M, Salas-Salvado J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Crit Rev Food Sci Nutr 2012;52:585-94.
- Allen SF, Godley RW, Evron JM, et al. Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids. Can J Cardiol 2014;30(12):1732 e13-1732 e15. PubMed
- Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol. 2008 Dec 7;14(45):6999-7004. PubMed
- Sharma T, Wong L, Tsai N, Wong RD. Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J. 2010 Aug;69(8):188-90.
- Rashid NN, Grant J. Hydroxycut hepatotoxicity. Med J Aust. 2010 Feb 1;192(3):173-4. PubMed
- Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. 2007 Oct;39(10):953-5. PubMed
- Corey R, Werner KT, Singer A, Moss A, Smith M, Noelting J, Rakela J. Acute liver failure associated with Garcinia cambogia use. Ann Hepatol. 2016 Jan-Feb;15(1):123-6. PubMed
- Melendez-Rosado J, Snipelisky D, Matcha G, Stancampiano F. Acute hepatitis induced by pure Garcinia cambogia. J Clin Gastroenterol. 2015 May-Jun;49(5):449-50. PubMed
- García-Cortés M, Robles-Díaz M, Ortega-Alonso A, Medina-Caliz I, Andrade RJ. Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int J Mol Sci. 2016 Apr 9;17(4):537. PubMed
- Dehoney S, Wellein M. Rhabdomyolysis associated with the nutritional supplement Hydroxycut. Am J Health Syst Pharm. 2009;66(2):142-8. PubMed
- Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561-6. PubMed
- Hendrickson BP, Shaikh N, Occhiogrosso M, Penzner JB. Mania Induced by Garcinia cambogia: A Case Series. Prim Care Companion CNS Disord. 2016;18(2).
- Kaswala D, Shah S, Patel N, Raisoni S, Swaminathan S. Hydroxycut-induced Liver Toxicity. Ann Med Health Sci Res. 2014; 4(1):143-5. PubMed
- Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol. 2009;15(14):1786-7. PubMed
- Lunsford KE, Bodzin AS, Reino DC, Wang HL, Busuttil RW. Dangerous dietary supplements: Garcinia cambogia -associated hepatic failure requiring transplantation. World J Gastroenterol. 2016;22(45):10071-10076.
- Narasimha A, Shetty PH, Nanjundaswamy MH, Viswanath B, Bada Math S. Hydroxycut - Dietary supplements for weight loss: Can they induce mania? Aust N Z J Psychiatry. 2013;47(12):1205-6. PubMed
- Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. 2009;54(2):406-8. PubMed
- Stohs SJ, Preuss HG, Ohia SE, et al. No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol. 2009;15(32):4087-9. PubMed
- Gavril A, Ribnikar M, Smid L, Luzar B, Stabuc B. Fat burner-induced acute liver injury: case series of four patients. Nutrition. 2018;47:110-114. doi: 10.1016/j.nut.2017.10.002. PubMed
- Bystrak T, Cervera-Hernandez ME, Reddy N, King Z, Bratberg J. Garcinia cambogia, diabetic ketoacidosis, and pancreatitis. R I Med J (2013). 2017 Oct 2;100(10):48-50. NO DOI
- Smith RJ, Bertilone C, Robertson AG. Fulminant liver failure and transplantation after use of dietary supplements. Med J Aust. 2016;204(1):30-2. PubMed
- Nguyen DC, Timmer TK, Davison BC, McGrane IR. Possible Garcinia cambogia-induced mania with psychosis: a case report. J Pharm Pract 2019;32(1):99-102. doi: 10.1177/0897190017734728.
- Yousaf MN, Chaudhary FS, Hodanazari SM, Sittambalam CD. Hepatotoxicity associated with Garcinia cambogia: a case report. World J Hepatol 2019;11(11):735-42.
- Mas Ordeig A, Bordón García N. Hepatotoxicity caused by Garcinia cambogia. Gastroenterol Hepatol 2020;43(3):134-5. DOI
- Cho HK, Han YS, Park JM. Ocular complications of Garcinia cambogia extract diet pills: case report. Eur J Ophthalmol 2019:1120672119872364. PubMed
- Ferreira V, Mathieu A, Soucy G, Giard JM, Erard-Poinsot D. Acute severe liver injury related to long-term Garcinia cambogia intake. ACG Case Rep J. 2020;7(8):e00429. PubMed
- Iqbal U, Anwar H, Siddiqui HU, Mehmood A. Acute Pancreatitis Secondary to Use of Appetite Suppressant: Garcinia cambogia. Cureus. 2019;11(5):e4676. PubMed
- Grigos A, Benmoussa J, Sandhu J, Chaucer B, Clarke M, SH Patel. Acute pancreatitis secondary to Garcinia cambogia; the unknown cost of herbal supplements. JOP. J Pancreas (Online) 2016; 17(3):316-317.
- Sidhu RLS, Labana S, Khehra L. Garcinia cambogia: a link between the "miracle" weight loss pill and acute pancreatitis. Am J Gastroenterol. 2016. 111:S560-S561. DOI
- Vuppalanchi R, Bonkovsky HL, Ahmad J, et al. Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol 2021. PubMed
- Calaquian LL, Yau I. Garcinia cambogia-A Supplement-Related Liver Injury. Cureus 2022;14(2):e22225. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC