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Dietary supplement

Goat's Rue Ingredients & Drug Interactions

by Mama's Select

Goat's Rue label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Goat's Rue against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Goat's Rue is a dietary supplement by Mama's Select with 1 active ingredient. Its ingredients are commonly taken for boosting breast milk supply, blood sugar support, traditional digestive remedy.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Goat's Rue. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Goat's Rue by Mama's Select

Ask about any prescription or over-the-counter medication and we check it for interactions with Goat's Rue by Mama's Select — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Goat's Rue by Mama's Select

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic Goat's Rue, a traditional herbal supplement. The capsule also includes inactive ingredients—rice flour, vegetable cellulose, stearic acid, magnesium stearate, and silicon dioxide—which are fillers and binders that help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Goat's Rue's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote natural milk production.
  • We looked for evidence on: Lactation, Breast milk supply, Galactagogue effect, Breastfeeding support.
  • The closest evidence on file: Goat's Rue is rated "Insufficient Reliable Evidence To Rate" for Lactation (Natural Medicines).

The evidence for Goat's Rue and lactation support is insufficient—we don't have reliable data to rate how well it works. It's traditionally used to support milk supply, but quality and safety vary considerably across products, so use only with professional guidance.

The evidence, ingredient by ingredient Goat's Rue

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The fresh plant can be toxic, and human safety data on Goat's Rue supplements are limited. The safety data advises against use during pregnancy.

If you're breastfeeding and considering this supplement, there isn't enough information on file to know either way—talk with your doctor or pharmacist for personalized advice on whether it's right for you.

Side effects, ingredient by ingredient Goat's Rue

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goat's Rue.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners and antiplatelet drugs—including aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, and ticlopidine—carry Moderate-severity interactions with Goat's Rue. Check your exact medications before taking this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Mama's Select Goat's Rue is marketed for lactation support, but the evidence for it isn't well established and the fresh plant carries toxicity concerns. If you take any blood thinner or antiplatelet medication, you'll need to clear it with your doctor or pharmacist first.

Discuss this supplement with your own healthcare provider before starting, especially if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Goat's Rue, straight from the product label.

Brand Mama's Select
Barcode (UPC) X000Q0OVQ9
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244110
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Female (18 - 50 Years), Lactating
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Goat's Rue by Mama's Select, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetable Capsule(s)
Maximum serving Sizes:
2 Vegetable Capsule(s)
Servings per container
60
UPC/BARCODE
X000Q0OVQ9
IngredientAmount% DV
organic Goat's Rue700 mg--

Other ingredients: Rice Flour, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Advanced formula "High potency" Designed to promote natural milk production

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the U.S.A.

GMP Good Manufacturing Practice Consistent Quality

Suggested/Recommended/Usage/Directions

Suggested Use: Adult women take 1-2 capsules, 4 times daily with a meal or as directed by a health care professional.

Precautions

Tamper Resistance: Please do not use if safety seal is broken or missing.

Warning: May interfere with diabetes treatment.

Caution: Not for use during pregnancy.

Do not use if you are under the age of 18.

Do not exceed recommended serving.

Consult your health care provider prior to using this or any other dietary supplement, especially if you are taking any medications, over the counter products, or other dietary supplements, or if you have or suspect you may have any medical condition.

Immediately discontinue use and call your health care provider if you experience any adverse reaction.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Please recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Goat's Rue by Mama's Select label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Goat's Rue label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Goat's Rue by Mama's Select

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Organic Goat's Rue

Interacts with
122 drugs
700 mg per serving

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research....

Organic Goat's Rue monograph & interactions

Other (inactive) ingredients: Rice Flour, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Goat's Rue by Mama's Select Drug Interactions

Want to check YOUR meds against Goat's Rue?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

organic Goat's Rue 122

Individual Drug Interactions

The ingredients in Goat's Rue interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Goat's Rue interact with drugs. Each result below shows which ingredient is responsible. organic Goat's Rue

Each ingredient & the kinds of drugs it affects

For each ingredient in Goat's Rue with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Goat's Rue1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Laboratory research suggests that goat's rue extract can inhibit platelet aggregation. Theoretically, goat's rue might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
organic Goat's Rue full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Goat's Rue, from the product label.

Mama's Select

See all Mama's Select products
Name
Mama's Select
Street Address
Suite 5731
City
Frisco
State
TX
ZipCode
75035
Web Address
www.MamasSelect.com
Pharmacist Counseling Corner

Goat's Rue by Mama's Select: Common Questions

Does Goat's Rue by Mama's Select interact with any medications?
Yes. Based on its ingredients, Goat's Rue has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Goat's Rue contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Goat's Rue safe during pregnancy?
No—the safety data advises against use during pregnancy. Talk with your doctor or pharmacist before taking it if you're pregnant or planning to become pregnant.
Can I take this while breastfeeding?
There isn't enough safety data on file to know either way. Although it's traditionally used to support milk supply, quality and safety vary. Discuss this with your doctor or pharmacist to decide what's right for you.
Does Goat's Rue actually work to increase milk supply?
The evidence is insufficient—we don't have reliable data to rate how well it works. It's traditionally used for lactation, but use only with professional guidance.
What is Goat's Rue used for?
It's traditionally used to support milk supply in nursing mothers, though the scientific evidence for its effectiveness is limited and quality varies across products.
Are there any side effects?
Our data don't list specific side effects, but note that the fresh plant can be toxic and human safety data on supplements are limited. Work with a healthcare provider if you have concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Goat's Rue is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Goat's Rue label
Go deeper

The Full Monographs Behind Goat's Rue’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Goat's Rue

Interacts with 122 drugs

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research. Solid human evidence for either use is...

Read the full Goat's Rue monograph →
Sources

Sources & How We Checked

Goat's Rue's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goat's Rue 6 references
  1. Atanasov AT. Effect of Galega officinalis L. extract on platelet aggregation in rats. J Herbs Spices Med Plants 1995;3:71-6.
  2. Atanasov, A. T. and Spasov, V. Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation. Folia Med.(Plovdiv.) 1999;41(1):46-50.
  3. Atanasov, A. T. and Spasov, V. Inhibiting and disaggregating effect of gel-filtered Galega officinalis L. herbal extract on platelet aggregation. J.Ethnopharmacol. 2000;69(3):235-240. PubMed
  4. Atanasov, A. T. and Tchorbanov, B. Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation. J.Med.Food 2002;5(4):229-234.
  5. Atanasov, A. T. and Tchorbanov, B. J. Antiplatelet aggregation activity of a fraction isolated from Galega officinalis L. J Herbs Spices Medicinal Plant 2002;10(2):63-71.
  6. Salatino S, Giacomelli L, Carnevali I, Giacomelli E. The role of natural galactagogues during breast feeding: focus on a Galega officinalis based food supplement. Minerva Pediatr. 2017 Dec;69(6):531-537. PubMed

See these in context on the Goat's Rue monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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