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Dietary supplement

Goat's Rue Ingredients & Drug Interactions

by Motherlove

Goat's Rue label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Goat's Rue against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Goat's Rue is a dietary supplement by Motherlove with 1 active ingredient. Its ingredients are commonly taken for boosting breast milk supply, blood sugar support, traditional digestive remedy.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Goat's Rue. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Goat's Rue by Motherlove

Ask about any prescription or over-the-counter medication and we check it for interactions with Goat's Rue by Motherlove — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Goat's Rue by Motherlove

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Motherlove Goat's Rue is a single-ingredient capsule: goat's rue, an herb traditionally used to support milk supply. The capsule also contains inactive ingredients—sunflower lecithin, modified cellulose, and medium chain triglycerides—which are fillers and binders that hold the supplement together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Goat's Rue's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support breast milk supply.
  • We looked for evidence on: Lactation.
  • The closest evidence on file: Goat's Rue is rated "Insufficient Reliable Evidence To Rate" for Lactation (Natural Medicines).

The evidence we hold on goat's rue for lactation shows insufficient reliable evidence to rate it. That means while it's been used traditionally to support milk supply, we don't have strong clinical data backing that use.

If you're thinking about using this for breastfeeding support, talk with your healthcare provider or lactation consultant about what the evidence actually shows and whether it's right for you.

The evidence, ingredient by ingredient Goat's Rue

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Goat's rue comes with a few cautions. The fresh plant can be toxic, and well-controlled human safety data on supplements are limited.

The safety data also advise against using it during pregnancy—there isn't enough data to know it's safe. Because quality and safety vary among supplements, use goat's rue only with professional guidance, especially if you're breastfeeding.

There are no adverse effects listed in our data, but that doesn't mean none have been reported.

Side effects, ingredient by ingredient Goat's Rue

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goat's Rue.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a blood thinner or antiplatelet drug—such as warfarin, aspirin, clopidogrel (Plavix), heparin, or enoxaparin (Lovenox)—check with your pharmacist or doctor before taking this product. Goat's rue may increase your bleeding risk with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Goat's Rue by Motherlove is traditionally used for milk supply, but the evidence isn't solid and safety data are sparse. If you take any blood thinner or antiplatelet drug, you'll need to clear it with your pharmacist or doctor first.

Pregnant people should avoid it. Talk to your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Goat's Rue, straight from the product label.

Brand Motherlove
Barcode (UPC) 759160543000
Net contents 60 Liquid Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334838
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Kosher, Adult Female (18 - 50 Years), Lactating, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Goat's Rue by Motherlove, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
759160543000
IngredientAmount% DV
Goat's Rue525 mg--

Other ingredients: Sunflower Lecithin, Modified Cellulose, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Take 1 capsule, 4 to 6 times throughout the day or as recommended by your healthcare practitioner.

Precautions

Discuss product use with a healthcare practitioner. Discontinue use if side effects appear. Sealed for your protection.

Any ingested food has the potential for an allergic reaction.

Keep out of reach of children.

Formulation

Vegan

Clean ingredients

Breastfeeding

Non GMO Project Verified Nongmoproject.org

Formulated for moms who: Want to support their milk supply Didn't increase in breast size during pregnancy Plan to relactate or adoptive feed

Made in the USA with imported ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Liquid capsules

Single-herb goat's rue supplement for breastfeeding moms

KOF-K (Kosher) Parve K-1604

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Non GMO Project Verified Nongmoproject.org Certified B Corporation

KOF-K (Kosher) Parve K-1604

Sustainable Forestry Initiative Certified Sourcing www.sfiprogram.org SFI-03531

General Statements

Mom-founded. Daughter-run. Founded over 30 years ago by an herbalist mom seeking to connect her own motherhood to Mother Earth, today Motherlove empowers all new moms with trusted remedies rooted in herbal wisdom. Scan to learn what makes our supplements superior. We're here for you from bump to birth, breastfeeding, and baby. Women Owned

Carton made with wind energy Printed with soy ink

Made with love Kathryn Higgins Founder. Mother. Herbalist Instagram @MotherLoveHerb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Goat's Rue by Motherlove label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Goat's Rue label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Goat's Rue by Motherlove

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Goat's Rue

Interacts with
122 drugs
525 mg per serving

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research....

Goat's Rue monograph & interactions

Other (inactive) ingredients: Sunflower Lecithin, Modified Cellulose, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Goat's Rue by Motherlove Drug Interactions

Want to check YOUR meds against Goat's Rue?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Goat's Rue 122

Individual Drug Interactions

The ingredients in Goat's Rue interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Goat's Rue interact with drugs. Each result below shows which ingredient is responsible. Goat's Rue

Each ingredient & the kinds of drugs it affects

For each ingredient in Goat's Rue with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Goat's Rue1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Laboratory research suggests that goat's rue extract can inhibit platelet aggregation. Theoretically, goat's rue might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Goat's Rue full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Goat's Rue, from the product label.

Motherlove

See all Motherlove products
Name
Motherlove Herbal Company
City
Fort Collins
State
CO
ZipCode
80524
Phone Number
970-493-2892
Web Address
motherlove.com
Pharmacist Counseling Corner

Goat's Rue by Motherlove: Common Questions

Does Goat's Rue by Motherlove interact with any medications?
Yes. Based on its ingredients, Goat's Rue has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Goat's Rue contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Goat's Rue safe to take while pregnant?
No. The safety data advise against using goat's rue during pregnancy because there isn't enough data to know it's safe. If you're pregnant or planning to become pregnant, talk with your doctor before taking this supplement.
Can I use this to increase my milk supply while breastfeeding?
Goat's rue is traditionally used for that purpose, but the evidence we hold shows insufficient reliable evidence to rate its effectiveness. Quality and safety also vary among supplements, so use it only with guidance from your doctor, midwife, or lactation consultant.
What is goat's rue supposed to do?
Goat's rue is an herb traditionally used to support milk supply in breastfeeding people. However, strong clinical evidence backing this use isn't established in our data.
Does this product have any fillers?
Yes. The capsule contains inactive ingredients: sunflower lecithin, modified cellulose, and medium chain triglycerides. These are fillers and binders that hold the supplement together.
Why is the fresh plant toxic but the supplement isn't?
We don't have detailed information on file explaining that difference. The fresh plant can be toxic, but well-controlled human safety data on the supplement itself are limited. Talk with your pharmacist or doctor about your specific concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Goat's Rue is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Goat's Rue label
Go deeper

The Full Monographs Behind Goat's Rue’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Goat's Rue

Interacts with 122 drugs

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research. Solid human evidence for either use is...

Read the full Goat's Rue monograph →
Sources

Sources & How We Checked

Goat's Rue's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goat's Rue 6 references
  1. Atanasov AT. Effect of Galega officinalis L. extract on platelet aggregation in rats. J Herbs Spices Med Plants 1995;3:71-6.
  2. Atanasov, A. T. and Spasov, V. Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation. Folia Med.(Plovdiv.) 1999;41(1):46-50.
  3. Atanasov, A. T. and Spasov, V. Inhibiting and disaggregating effect of gel-filtered Galega officinalis L. herbal extract on platelet aggregation. J.Ethnopharmacol. 2000;69(3):235-240. PubMed
  4. Atanasov, A. T. and Tchorbanov, B. Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation. J.Med.Food 2002;5(4):229-234.
  5. Atanasov, A. T. and Tchorbanov, B. J. Antiplatelet aggregation activity of a fraction isolated from Galega officinalis L. J Herbs Spices Medicinal Plant 2002;10(2):63-71.
  6. Salatino S, Giacomelli L, Carnevali I, Giacomelli E. The role of natural galactagogues during breast feeding: focus on a Galega officinalis based food supplement. Minerva Pediatr. 2017 Dec;69(6):531-537. PubMed

See these in context on the Goat's Rue monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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