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Dietary supplement

Goji Berry Extract 600 mg Ingredients & Drug Interactions

by Doctor's Best

Capsule Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Goji Berry Extract 600 mg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for general antioxidant support, eye health, immune support.Based on those ingredients, 1,000 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Goji berry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Goji Berry Extract 600 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: goji berry extract at 600 mg per capsule. Goji berry is a dried fruit from a plant traditionally used in Chinese medicine, and the extract concentrates its compounds into supplement form.

The capsule also contains inactive ingredients — maltodextrin, hypromellose, brown rice powder, calcium silicate, and silicon dioxide — which are fillers, binders, and flow agents that help form and deliver the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Goji's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune system, eye health and skin complexion.
  • We looked for evidence on: Age-related macular degeneration (AMD), Dry eye, skin health, antioxidant support.
  • The closest evidence on file: Goji is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Goji is rated "Insufficient Reliable Evidence To Rate" for Dry eye.

The evidence we hold doesn't establish that goji berry extract works for any of the health claims sometimes made about it. The conditions listed — sunburn, cardiovascular disease, high blood pressure, obesity, and quality of life — all have insufficient reliable evidence to rate in our data.

That doesn't mean it doesn't work; it means the research available to us hasn't proven it does.

The evidence, ingredient by ingredient Goji

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Goji berries are generally well tolerated as a food, but concentrated supplements like this one have less safety testing behind them. A small number of people have reported allergic reactions — ranging from itching and facial swelling to, rarely, anaphylaxis — after consuming goji berries.

There are also isolated case reports of liver inflammation linked to goji consumption, though in some cases other ingredients in combination products may have played a role. If you're pregnant, avoid medicinal amounts of goji due to limited safety data and traditional reports suggesting it may affect the uterus.

If you're breastfeeding, there isn't enough reliable data on supplement use, so talk with your doctor or pharmacist before starting it.

Side effects, ingredient by ingredient Goji

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goji.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,001 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check the following medication types with your doctor or pharmacist: blood thinners like warfarin (Major risk of increased bleeding), heart rhythm medications, blood pressure drugs, diabetes medications, and any drug processed through your liver's cytochrome P450 enzymes — which is a large group including certain antidepressants, antihistamines, and many others. In vitro research shows goji may slow how your liver breaks these down.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Goji Berry Extract is marketed for several health purposes, but the evidence supporting those claims isn't established in our data. The main reason to be careful with this product is its interactions with medications — especially blood thinners, heart drugs, and diabetes medications.

If you take any prescription medications, check them against the interaction tool on this page, and talk with your doctor or pharmacist before starting this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Goji Berry Extract 600 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950001534
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302669
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Goji Berry Extract 600 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
753950001534
IngredientAmount% DV
Goji berry extract600 mg--

Other ingredients: Maltodextrin, Hypromellose, Brown Rice, Powder, Calcium Silicate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best Goji Berry Extract contains Goji berry extract from Goji berry (Lycium barbarum) fruit originated from Asia.

Formulation

For centuries, traditional herbalists have recognized the various health benefits of Goji berries in addition to its status as a highly nutritious food. Goji berries have long been revered as a universal tonic for their longevity-enhancing effect. Goji berries are renowned for it various health benefits that help support immune system, eye health, as well as provide beneficial effects on skin complexion. Helps support immune system Helps support eye health Helps support skin complexion

Helps support immune system, eye health and skin complexion

Vegan

Non-GMO Gluten free

Vegan

This product contains natural ingredients that may vary in color.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Doctor's Best Science-Based Nutrition

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Adult Use: take 1 capsule up to 4 times a day, with or without food, or as recommended by a nutritionally informed physician.

Precautions

Warning: Consult your physician before using any health supplement if you have a medical condition, or taking medications for diabetes, blood pressure or warfarin.

Storage

Store in a cool dry place.

See for yourself

Goji Berry Extract 600 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Goji Berry Extract 600 mg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Goji berry extract

Interacts with
1,000 drugs
600 mg per serving

Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they...

Goji berry extract monograph & interactions

Other (inactive) ingredients: Maltodextrin, Hypromellose, Brown Rice, Powder, Calcium Silicate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Goji Berry Extract 600 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against Goji Berry Extract 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,000Drugs
2 Major 930 Moderate 68 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Goji Berry Extract 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Goji berry extract8 drug types · 1,000 drugs

Warfarin (Coumadin)

Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
There are at least 5 case reports of increased international normalized ratio (INR) in patients stabilized on warfarin who began drinking goji juice, concentrated goji tea, or goji wine. Goji may inhibit the metabolism of warfarin by cytochrome P450 2C9 (CYP2C9).

Likelihood Probable Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Animal and in vitro research suggest that goji root bark has hypotensive effects. However, goji fruit juice does not appear to reduce systolic or diastolic blood pressure in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, goji berry might inhibit CYP2C19 and reduce metabolism of CYP2C19 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C19 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2C19 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C9 enzymes. Additionally, multiple case reports suggest that goji berry concentrated tea and juice inhibit the metabolism of warfarin, a CYP2C9 substrate. Concomitant use with goji may decrease metabolism and increase levels of CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
In vitro research shows that goji berry juice inhibits CYP2D6 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2D6 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
In vitro research shows that goji berry juice inhibits CYP3A4 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP3A4 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Flecainide (Tambocor)

Theoretically, goji berry might increase the levels and clinical effects of flecainide.
In one case report, a 75-year-old patient stable on flecainide and warfarin presented to the emergency room with fainting and pleomorphic arrhythmia caused by flecainide toxicity. Flecainide toxicity was attributed to drinking 1-2 glasses of concentrated goji tea daily for 2 weeks. Theoretically, goji may have inhibited the cytochrome P450 2D6 (CYP2D6) metabolism of flecainide.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Animal and in vitro research show that goji root bark and fruit polysaccharides might have hypoglycemic effects. However, clinical research has only shown that taking goji fruit polysaccharides with or without antidiabetes drugs modestly reduces postprandial glucose when compared with control, with no reports of hypoglycemia.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Goji Berry Extract 600 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
Tustin
State
California
ZipCode
92780
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Goji Berry Extract 600 mg by Doctor's Best: Common Questions

Does Goji Berry Extract 600 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Goji Berry Extract 600 mg has a known interaction with 1,000 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Goji Berry Extract 600 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is goji berry extract safe to take while pregnant?
No. The safety data is limited, and traditional medicine reports suggest goji may affect the uterus. Avoid medicinal amounts during pregnancy and talk with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
There isn't enough reliable data on goji supplements during breastfeeding to know whether it's safe. Talk with your doctor or pharmacist before starting it.
Can goji berry extract help with weight loss or high blood pressure?
The evidence in our data is insufficient to rate whether it works for obesity or high blood pressure. While some animal studies suggest goji root bark may lower blood pressure, human studies of goji fruit juice haven't shown that effect.
What side effects has goji berry caused?
Most people tolerate goji berries well, but allergic reactions have been reported — including itching, mouth and throat irritation, facial swelling, and rarely anaphylaxis. Isolated cases of liver inflammation have also been reported, though it's unclear whether goji or other ingredients were responsible.
Why does goji interact with so many medications?
Goji appears to slow down the liver enzymes (cytochrome P450 systems) that break down many drugs. When your liver processes a drug more slowly, that drug can build up to higher levels in your body, potentially causing side effects or overdose-like symptoms. Warfarin is the one case where this has actually been documented in people.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Goji Berry Extract 600 mg label
Go deeper

The Full Monographs Behind Goji Berry Extract 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Goji Berry Extract 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goji 14 references
  1. Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. Boca Raton, FL: CRC Press, LLC 1999.
  2. Lam AY, Elmer GW, Mohutsky MA. Possible interaction between warfarin and Lycium Barbarum. Ann Pharmacother 2001;35:1199-201.
  3. Leung H, Hung A, Hui AC, Chan TY. Warfarin overdose due to the possible effects of Lycium barbarum L. Food Chem Toxicol 2008;46:1860-2. PubMed
  4. Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. J Altern Complement Med 2008;14:403-12.
  5. Rivera, C. A., Ferro, C. L., Bursua, A. J., and Gerber, B. S. Probable interaction between Lycium barbarum (goji) and warfarin. Pharmacotherapy 2012;32(3):e50-e53.
  6. Monzon, Ballarin S., Lopez-Matas, M. A., Saenz, Abad D., Perez-Cinto, N., and Carnes, J. Anaphylaxis associated with the ingestion of Goji berries (Lycium barbarum). J.Investig.Allergol.Clin.Immunol. 2011;21(7):567-570.
  7. Franco, M., Monmany, J., Domingo, P., and Turbau, M. [Autoimmune hepatitis triggered by consumption of Goji berries]. Med.Clin.(Barc.) 9-22-2012;139(7):320-321.
  8. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
  9. Larramendi CH, García-Abujeta JL, Vicario S, García-Endrino A, López-Matas MA, García-Sedeño MD, et al. Goji berries (Lycium barbarum): Risk of allergic reactions in individuals with food allergy. J Investig Allergol Clin Immunol. 2012;22(5):345-50.
  10. Cai H, Liu F, Zuo P, Huang G, Song Z, Wang T, et al. Practical application of antidiabetic efficacy of Lycium barbarum polysaccharide in patients with type 2 diabetes. Med Chem. 2015;11(4):383-90.
  11. Potterat O. Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Med 2010;76(1):7-19.
  12. Guzmán CE, Guzmán-Moreno CG, Assad-Morell JL, Edgar Francisco Carrizales-Sepúlveda EF. Flecainide toxicity associated with the use of goji berries: a case report. Eur Heart J Case Rep. 2021;5(6):ytab204. PubMed
  13. Liu R, Tam TW, Mao J, et al. In vitro activity of Lycium barbarum (Goji) against major human phase I metabolism enzymes. Complement Integr Med. 2016;13(3):257-265.
  14. Zhang J, Tian L, Xie B. Bleeding due to a probable interaction between warfarin and Gouqizi (Lycium Barbarum L.). Toxicol Rep. 2015;2:1209-1212. PubMed

See these in context on the Goji monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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