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Dietary supplement

Gotu Kola Ingredients & Drug Interactions

by Herbal Hills

Gotu Kola label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gotu Kola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gotu Kola is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gotu Kola, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Gotu Kola by Herbal Hills

Ask about any prescription or over-the-counter medication and we check it for interactions with Gotu Kola by Herbal Hills — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Gotu Kola by Herbal Hills

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gotu kola powder. Gotu kola is a plant traditionally used in herbal medicine, and this is the single-ingredient formula — no fillers or other actives added.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Gotu Kola's overall clinical evidence instead.

Moderate

Some clinical evidence supports Gotu Kola for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Burns — rated "Possibly Effective" (Natural Medicines).
  • On file: Venous insufficiency — rated "Possibly Effective" (Natural Medicines).

The evidence on gotu kola is mixed. It's rated possibly effective for venous insufficiency (poor circulation in the legs) and possibly effective for burns.

For radiation dermatitis (skin damage from radiation therapy), cognitive function, and Alzheimer disease, either the evidence suggests it doesn't work or there simply isn't enough reliable research to know either way.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated over the short term, though the quality of safety evidence is limited. The most common side effects when taken by mouth are stomach irritation and nausea.

Applied to the skin, it can occasionally cause eczema or an allergic rash. Liver toxicity is rare but has been reported in a handful of cases — though it's unclear whether gotu kola itself or contaminants in those products were responsible.

In a clinical trial where liver function was carefully monitored, 120 mg daily for 6 months did not cause changes in liver tests. There isn't enough safety data in pregnancy, so it's traditionally been avoided during that time.

Safety during breastfeeding is unknown, and it's best avoided then too. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start gotu kola, double-check with your pharmacist or doctor if you take any hepatotoxic drugs (drugs that can stress the liver) or CNS depressants like sedatives, sleep aids, or strong pain medications. Both are Moderate-severity interactions that could amplify drug effects or liver risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu kola may be worth considering if you're looking into a herbal option for venous insufficiency or burns, though the evidence is moderate at best. If you take sedatives, pain medications, or any drug known to affect the liver, check your exact medications with your pharmacist or doctor before starting — the interactions at play are real and could affect how those drugs work or increase side effects.

Pregnant or breastfeeding? This one's best avoided until you've talked it over with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gotu Kola, straight from the product label.

Brand Herbal Hills
Barcode (UPC) 8904268846153
Net contents 16 Ounce(s); 454 Gram(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 296406
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gotu Kola by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
151
UPC/BARCODE
8904268846153
IngredientAmount% DV
Gotu Kola, Powder3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Herbal Hills Back to Nature

General Statements

High Quality Natural Products

Neutral code: MH/AYU/25D-MH/102334 28156-2569

Formula

Mandukparnee Centella asiatica

Halal India HIW25610218

Suggested/Recommended/Usage/Directions

Directions for use: Take 3 gms powder, 1 to 2 times a day

Precautions

Warning: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Keep out of reach of children.

Do not use if pouch is broken.

Please consult an expert before use.

Storage

Storage: Store in a cool dry place away from the direct sunlight.

Formulation

Being Natural product, colour may vary over time as well as from batch to batch however effectiveness remains same.

Country of Origin: India

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

QA ICS JAS-ANZ GMP Good Manufacturing Practice Halal India HIW25610218

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gotu Kola by Herbal Hills label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gotu Kola label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gotu Kola by Herbal Hills

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container151 Amounts shown are per serving.

Gotu Kola, Powder

Interacts with
579 drugs
3 Gram(s) per serving

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Gotu Kola, Powder monograph & interactions
Interaction report

Gotu Kola by Herbal Hills Drug Interactions

Want to check YOUR meds against Gotu Kola?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

Gotu Kola, Powder 579

Individual Drug Interactions

The ingredients in Gotu Kola interact with 579 drugs. Click any drug to see the details.

1 of the 1 ingredient in Gotu Kola interact with drugs. Each result below shows which ingredient is responsible. Gotu Kola, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Gotu Kola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gotu Kola, Powder2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
Gotu Kola, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gotu Kola, from the product label.

Herbal Hills

See all Herbal Hills products
Name
Stelcore Management Services LLC (Importer)
Street Address
8 Green Suite 5766
City
Dover
State
Delaware
ZipCode
19901
Pharmacist Counseling Corner

Gotu Kola by Herbal Hills: Common Questions

Does Gotu Kola by Herbal Hills interact with any medications?
Yes. Based on its ingredients, Gotu Kola has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gotu Kola contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take gotu kola if I'm pregnant?
There isn't enough safety data to know for sure. It's traditionally been avoided in pregnancy. Talk with your doctor or pharmacist about your specific situation before taking it.
What are the side effects?
Most commonly, stomach irritation and nausea when taken by mouth. If you apply it to skin, it may occasionally cause eczema or an allergic rash. Liver toxicity is rare but has been reported.
Does gotu kola really work for memory or brain health?
The evidence isn't strong enough to say it works. For Alzheimer disease and general cognitive function, we don't have reliable research showing it's effective.
Is it safe to take long-term?
It's generally well tolerated in the short term, but quality long-term safety data is limited. If you're thinking of taking it regularly, discuss that with your doctor or pharmacist, especially if you have liver concerns.
Will this help my circulation problems?
Gotu kola is rated possibly effective for venous insufficiency — that's the circulation issue in the legs. It's not a sure thing, but there's some evidence it may help.
Can I use gotu kola while breastfeeding?
Safety during breastfeeding isn't known, so it's best avoided. Talk with your doctor or pharmacist if you're considering it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gotu Kola is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gotu Kola label
Go deeper

The Full Monographs Behind Gotu Kola’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Sources

Sources & How We Checked

Gotu Kola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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