Happy Tummy Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Happy Tummy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Happy Tummy is a dietary supplement by Banyan Botanicals with 5 active ingredients. Its ingredients are commonly taken for digestive upset and bloating, infant colic, menstrual cramps.Based on those ingredients, 1,300 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ajowan, Fennel, Coriander. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Happy Tummy by Banyan Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Happy Tummy by Banyan Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Happy Tummy by Banyan Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Happy Tummy contains 5 active ingredients in a proprietary blend: fennel, coriander, sesame, ajowan (also called bishop's weed), and mineral salt. These are traditional digestive botanicals — fennel and coriander are carminatives meant to ease gas and bloating, sesame contributes nutritional compounds, ajowan adds digestive support, and mineral salt aids electrolyte balance.
The product contains no inactive fillers or other ingredients listed.
Does it work?
Moderate evidence
The evidence for this blend is thin. Fennel is possibly effective for painful periods (dysmenorrhea); beyond that, it has insufficient evidence for its other uses including bronchitis, anxiety, and bedwetting.
Coriander shows insufficient evidence for loss of appetite, anxiety, constipation, diabetes, diarrhea, and indigestion. Sesame is possibly effective for high blood pressure and possibly ineffective for cough; it's insufficient for fatty liver disease, HIV-related weight loss, Alzheimer's, and anemia.
Ajowan has no effectiveness ratings in our data. If digestive comfort is your goal, the evidence doesn't firmly establish that this blend will deliver it.
How safe is it?
Well-documented data
Fennel is well tolerated in food amounts but needs caution at medicinal doses. The most common side effects are stomach discomfort, sun sensitivity, and allergic reactions in sensitive people.
Rare but serious: seizures have been reported. Fennel is possibly unsafe in pregnancy and lactation due to its hormone-like effects and limited safety data.
Coriander is generally safe at food amounts but lacks safety data for medicinal doses; it's well tolerated but can cause contact skin irritation topically, and anaphylaxis (a severe allergic reaction) has been reported orally in rare cases. Pregnancy and lactation safety data are not on file.
Sesame is generally safe at food amounts but is a major allergen — up to 0.5% of the U.S. population reports sesame allergy — and one case of diarrhea appeared in clinical trials. Pregnancy and lactation safety are unknown.
Ajowan contains light-sensitizing compounds and is toxic; it causes nausea, vomiting, and headache orally, and can cause phototoxic skin damage topically. It is likely unsafe in pregnancy and safety is unknown in lactation.
Meds to double-check
Moderate interaction found
Before taking Happy Tummy, check with your doctor or pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs like warfarin, heparin, aspirin, or clopidogrel — fennel and ajowan may increase bleeding risk. Also clear it if you're on birth control pills, hormone replacement therapy, blood pressure medications, diabetes drugs, sedatives, photosensitizing drugs (certain antibiotics and antidepressants), tamoxifen, or drugs your liver breaks down via CYP3A4 or CYP2C9 pathways — this product may change how they work.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Happy Tummy is a traditional digestive blend, but the science behind it is sparse — most ingredients lack solid evidence for their intended uses. More importantly, it carries documented interactions with blood thinners, blood pressure drugs, diabetes medications, birth control, antibiotics, and several other medication types.
If you take any prescription medication, check your exact drugs with the search tool on this page before you start, and talk it over with your doctor or pharmacist. It's not suitable during pregnancy or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Happy Tummy, straight from the product label.
| Brand | Banyan Botanicals |
|---|---|
| Barcode (UPC) | 600000003775 |
| Net contents | 4 Ounce(s); 113 Gram(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2021 |
| DSLD ID | 247244 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Happy Tummy by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0 NP | -- |
| Fennel | 0 NP | -- |
| Coriander | 0 NP | -- |
| Sesame | 0 NP | -- |
| Ajowan | 0 NP | -- |
| Mineral Salt | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1/2 teaspoon to be chewed after each meal.
Storage
Needs no refrigeration.
Formulation
Traditional Ayurvedic rejuvenative. Kindles agni. Said to promote vitality, creativity, digestion and fresh breath.
(An ancient ayurvedic formula) Sidha Soma Supreme
Precautions
Warning: If consumer is under medical care, pregnant, lactating, or a child, seek advice of a healthcare professional before use.
Warning: If consumer is under medical care, pregnant, lactating, or a child, seek advice of a healthcare professional before use.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Happy Tummy by Banyan Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Happy Tummy by Banyan Botanicals
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1.3 Gram(s) Dosage formPowder Servings per container87 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Happy Tummy by Banyan Botanicals Drug Interactions
HelloPharmacist Interaction Report
Happy Tummy by Banyan Botanicals interacts with medications through its fennel, coriander, sesame, and ajowan content.
The most serious documented interaction is fennel's theoretical effect on blood thinners (anticoagulants) — it may increase bleeding risk when combined with drugs like warfarin, heparin, or aspirin, based on animal evidence that fennel has antiplatelet properties.
Read the full breakdown — every affected drug type, severity by severity
Fennel also affects contraceptive drugs and hormone replacement therapy (estrogens) by competing for estrogen receptors; it may reduce how well certain antibiotics like ciprofloxacin work by nearly 50%; and it theoretically raises levels of drugs your liver metabolizes through the CYP3A4 pathway. Coriander carries its own Moderate concerns: it may add to the drowsiness of sedatives (CNS depressants), lower blood pressure with antihypertensive drugs, increase photosensitivity risk with certain medications, and raise the risk of low blood sugar (hypoglycemia) when combined with diabetes medications.
Sesame can lower blood pressure and blood sugar further, potentially causing unwanted dips when you're already on blood pressure or diabetes drugs; it may also interfere with tamoxifen (a breast cancer medication) and theoretically affects how your body handles certain heart and blood-thinning drugs through the CYP2C9 pathway.
Ajowan (bishop's weed) carries Moderate interactions with photosensitizing drugs (including some antibiotics and antidepressants), drugs broken down by CYP3A4, and blood thinners — again, raising bleeding risk. We were unable to check mineral salt, as we hold no data for it.
Altogether, these interactions span 1,301 individual medications. Use the search tool below to check your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Happy Tummy?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Happy Tummy interact with 1,300 drugs. Click any drug to see the details.
4 of the 5 ingredients in Happy Tummy interact with drugs. Each result below shows which ingredient is responsible. Ajowan Fennel Coriander Sesame
Insulin Glargine RecombinantToujeo Solostar
How Insulin Glargine Recombinant interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Glargine Recombinant interactionSesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Glargine Recombinant interactionInsulin Glargine, LixisenatideSoliqua 100/33
How Insulin Glargine, Lixisenatide interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
SesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Glargine, Lixisenatide interactionCorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Glargine, Lixisenatide interactionInsulin Glulisine (rdna)Apidra
How Insulin Glulisine (rdna) interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Glulisine (rdna) interactionSesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Glulisine (rdna) interactionInsulin Human, Sodium ChlorideMyxredlin
How Insulin Human, Sodium Chloride interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
SesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Human, Sodium Chloride interactionCorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Human, Sodium Chloride interactionInsulin LisproAdmelog, Admelog Solostar
How Insulin Lispro interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Lispro interactionSesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Lispro interactionInsulin Lispro RecombinantHumalog Kwikpen
How Insulin Lispro Recombinant interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
SesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Lispro Recombinant interactionCorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Lispro Recombinant interactionInsulin Lispro-aabcLyumjev
How Insulin Lispro-aabc interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Lispro-aabc interactionSesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Lispro-aabc interactionInsulin DetermirLevemir
How Insulin Determir interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
SesameAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame + Insulin Determir interactionCorianderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Coriander + Insulin Determir interactionInterferon Alfa-2bIntron A, Rebetron, Viraferon
How Interferon Alfa-2b interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Alfa-2b interactionCorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Alfa-2b interactionInterferon Alfa-n3Alferon N
How Interferon Alfa-n3 interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Alfa-n3 interactionAjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Alfa-n3 interactionInterferon Alfacon-1Infergen
How Interferon Alfacon-1 interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Alfacon-1 interactionCorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Alfacon-1 interactionInterferon Beta-1aAvonex, Rebif
How Interferon Beta-1a interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Beta-1a interactionAjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Beta-1a interactionInterferon Beta-1bBetaferon, Betaseron, Extavia
How Interferon Beta-1b interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Beta-1b interactionCorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Beta-1b interactionInterferon Gamma-1bActimmune
How Interferon Gamma-1b interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Interferon Gamma-1b interactionAjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Interferon Gamma-1b interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
SesameCytochrome P450 2c9 (cyp2c9) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame + Irbesartan interactionCorianderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Coriander + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Happy Tummy — through 3 ingredients. Tap an ingredient for the detail:
CorianderAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Coriander + Irbesartan, Hydrochlorothiazide interactionAjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Irbesartan, Hydrochlorothiazide interactionSesameAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame + Irbesartan, Hydrochlorothiazide interactionIrinotecanCamptosar, Onivyde
How Irinotecan interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Irinotecan interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Irinotecan interactionIrinotecan Hydrochloride
How Irinotecan Hydrochloride interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Irinotecan Hydrochloride interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Irinotecan Hydrochloride interactionIsavuconazonium Sulfate
How Isavuconazonium Sulfate interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Isavuconazonium Sulfate interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Isavuconazonium Sulfate interactionIsavuconazonium Sulfate (iv)Cresemba
How Isavuconazonium Sulfate (iv) interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Isavuconazonium Sulfate (iv) interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Isavuconazonium Sulfate (iv) interactionIsavuconazonium Sulfate (oral)Cresemba
How Isavuconazonium Sulfate (oral) interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Isavuconazonium Sulfate (oral) interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Isavuconazonium Sulfate (oral) interactionIsoniazid, Pyrazinamide, RifampinRifater
How Isoniazid, Pyrazinamide, Rifampin interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Isoniazid, Pyrazinamide, Rifampin interactionCorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Isoniazid, Pyrazinamide, Rifampin interactionIsopropamide, ProchlorperazineCombid
How Isopropamide, Prochlorperazine interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Isopropamide, Prochlorperazine interactionAjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Isopropamide, Prochlorperazine interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
CorianderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Coriander + Isosorbide Dinitrate, Hydralazine interactionSesameAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame + Isosorbide Dinitrate, Hydralazine interactionIsotretinoinAbsorica, Accutane, Amnesteem, Claravis, Roaccutane, Sotret
How Isotretinoin interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajowan + Isotretinoin interactionCorianderPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Coriander + Isotretinoin interactionIsradipineDynacirc CR
How Isradipine interacts with Happy Tummy — through 4 ingredients. Tap an ingredient for the detail:
SesameAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame + Isradipine interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Isradipine interactionCorianderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Coriander + Isradipine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Isradipine interactionIstradefyllineNourianz
How Istradefylline interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Istradefylline interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Istradefylline interactionItraconazoleSporanox, Sporanox Injection, Tolsura
How Itraconazole interacts with Happy Tummy — through 3 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Itraconazole interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Itraconazole interactionSesameP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
Read the full Sesame + Itraconazole interactionIvabradineCoralan, Corlanor, Corlentor, Procoralan
How Ivabradine interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
AjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Ivabradine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Ivabradine interactionIvacaftorKalydeco
How Ivacaftor interacts with Happy Tummy — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Ivacaftor interactionAjowanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajowan + Ivacaftor interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Happy Tummy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Ajowan
Anticoagulant/Antiplatelet Drugs
Bergapten, a constituent of bishop's weed, has antiplatelet activity. Theoretically, bishop's weed might have additive effects with anticoagulant or antiplatelet drugs and possibly increase the risk of bleeding.
Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro. Theoretically, bishop's weed might inhibit elimination and increase blood levels of drugs metabolized by CYP3A4.
Some drugs metabolized by CYP3A4 include alprazolam (Xanax), amitriptyline (Elavil), amiodarone (Cordarone), buspirone (Buspar), cerivastatin (Baycol), citalopram (Celexa), felodipine (Plendil), fexofenadine (Allegra), itraconazole (Sporanox), ketoconazole (Nizoral), lansoprazole (Prevacid), losartan (Cozaar), lovastatin (Mevacor), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), sildenafil (Viagra), simvastatin (Zocor), verapamil (Calan, Covera-HS, Isoptin), and many others.
Photosensitizing Drugs
Bishop's weed constituents seem to cause photosensitivity. Theoretically, concomitant use of bishop's weed with photosensitizing drugs might result in increased photosensitivity.
Some drugs that cause photosensitivity include amitriptyline (Elavil), quinolones (Ciprofloxacin, others), sulfa drugs (Septra, Bactrim, others), and tetracycline.
Fennel
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
Coriander
Antidiabetes Drugs
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Antihypertensive Drugs
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.
Cns Depressants
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.
Photosensitizing Drugs
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.
Sesame
Antidiabetes Drugs
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical studies show that sesame oil can decrease plasma glucose and glycated hemoglobin (HbA1c) levels. Some clinical research in patients taking glibenclamide shows that using sesame oil or a blend of sesame oil and rice bran oil in place of other oil for cooking reduces plasma glucose more than glibenclamide alone. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Antihypertensive Drugs
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that replacing other cooking oil with sesame oil can lower systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with or without hypertension. There is also some evidence that sesame oil has additive effects in patients also taking atenolol, nifedipine, and/or hydrochlorothiazide. In patients using nifedipine, using a blend of sesame oil and rice bran oil for cooking reduces both SBP and DBP more than nifedipine alone.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
In vitro, sesame inhibits CYP2C9. However, this interaction has not been reported in humans.
Tamoxifen (Nolvadex)
Theoretically, sesame might interfere with tamoxifen.
In animal research, sesame seed reduces the tumor-inhibitory effect of tamoxifen by reducing apoptosis and increasing proliferation. This interaction has not been reported in humans.
P-Glycoprotein Substrates
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
In vitro research suggests that sesamin, a constituent of sesame, can inhibit the multi-drug transporter protein, P-glycoprotein. However, this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Happy Tummy, from the product label.
Banyan Botanicals
See all Banyan Botanicals products- Name
- Banyan Botanicals
- City
- Albuquerque
- State
- NM
- ZipCode
- 87113
- Web Address
- banyanbotanicals.com
Happy Tummy by Banyan Botanicals: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Happy Tummy’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fennel
Interacts with 742 drugsFennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...
Read the full Fennel monograph → Herb & supplement monographCoriander
Interacts with 717 drugsCoriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people,...
Read the full Coriander monograph → Herb & supplement monographSesame
Interacts with 529 drugsSesame is a nutritious seed and oil widely used in cooking and traditional medicine, and it provides healthy fats, fiber, and antioxidant compounds called lignans. Some early research sugges...
Read the full Sesame monograph → Herb & supplement monographBishop's Weed
Interacts with 956 drugsBishop's Weed (Ammi majus) is a flowering plant whose seeds contain natural light-sensitizing compounds called psoralens, which have been studied mainly for skin conditions like vitiligo and...
Read the full Bishop's Weed monograph →Sources & How We Checked
Happy Tummy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 90 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fennel 17 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
- Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
- Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
- Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Subehan, Zaidi, S. F., Kadota, S., and Tezuka, Y. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. J Agric.Food Chem. 12-12-2007;55(25):101 PubMed
- LEVY, S. B. Bronchial asthma due to ingestion of fennel and fennel seed. Ann.Allergy 1948;6(4):415.
- Ottolenghi, A., De Chiara, A., Arrigoni, S., Terracciano, L., and De Amici, M. [Diagnosis of food allergy caused by fruit and vegetables in children with atopic dermatitis]. Pediatr Med Chir 1995;17(6):525-530.
- Trabace L, Tucci P, Ciuffreda L, et al. "Natural" relief of pregnancy-related symptoms and neonatal outcomes: above all do no harm. J Ethnopharmacol. 2015;174:396-402. PubMed
- Denaxa D, Arkwright PD. Fennel as a cause of immediate hypersensitivity to toothpaste. Ann Allergy Asthma Immunol. 2020;125(1):99-100. PubMed
- Lee HW, Ang L, Lee MS, Alimoradi Z, Kim E. Fennel for reducing pain in primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. Nutrients 2020;12(11):3438. PubMed
- Mathew T, John SK, Javali M, Vasireddy M, Nadig R, Sarma GRK. Substance use related cluster headache: A case series. Headache 2022;62(7):908-910. PubMed
Coriander 12 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
- Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
- Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
- Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
- Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
- Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
- Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
- van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
- Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
- Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
- Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed
Sesame 53 references
- von Moltke LL, Weemhoff JL, Bedir E, et al. Inhibition of human cytochromes P450 by components of Ginkgo biloba. J Pharm Pharmacol 2004;56:1039-44.
- Sankar, D., Sambandam, G., Ramakrishna, Rao M., and Pugalendi, K. V. Modulation of blood pressure, lipid profiles and redox status in hypertensive patients taking different edible oils. Clin Chim Acta 2005;355(1-2):97-104. PubMed
- Sankar, D., Rao, M. R., Sambandam, G., and Pugalendi, K. V. A pilot study of open label sesame oil in hypertensive diabetics. J Med Food 2006;9(3):408-412. PubMed
- Sankar, D., Rao, M. R., Sambandam, G., and Pugalendi, K. V. Effect of sesame oil on diuretics or Beta-blockers in the modulation of blood pressure, anthropometry, lipid profile, and redox status. Yale J Biol.Med. 2006;79(1):19-26.
- Sacco, S. M., Chen, J., Power, K. A., Ward, W. E., and Thompson, L. U. Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors. Menop PubMed
- Sacco, S. M., Power, K. A., Chen, J., Ward, W. E., and Thompson, L. U. Interaction of sesame seed and tamoxifen on tumor growth and bone health in athymic mice. Exp Biol Med (Maywood) 2007;232(6):754-761.
- Hsiao, E. S., Lin, L. J., Li, F. Y., Wang, M. M., Liao, M. Y., and Tzen, J. T. Gene families encoding isoforms of two major sesame seed storage proteins, 11S globulin and 2S albumin. J Agric Food Chem 2006;54(25):9544-9550. PubMed
- Ramesh, B., Saravanan, R., and Pugalendi, K. V. Influence of sesame oil on blood glucose, lipid peroxidation, and antioxidant status in streptozotocin diabetic rats. J Med Food 2005;8(3):377-381. PubMed
- Panizzolo, C., Tura, M., and Barbato, A. Anaphylaxis to sesame paste. Eur Ann Allergy Clin Immunol 2005;37(1):34-35.
- Leduc, V., Moneret-Vautrin, D. A., Tzen, J. T., Morisset, M., Guerin, L., and Kanny, G. Identification of oleosins as major allergens in sesame seed allergic patients. Allergy 2006;61(3):349-356. PubMed
- Agne, P. S., Bidat, E., Agne, P. S., Rance, F., and Paty, E. Sesame seed allergy in children. Eur Ann Allergy Clin Immunol 2004;36(8):300-305.
- Dalal, I., Binson, I., Levine, A., Somekh, E., Ballin, A., and Reifen, R. The pattern of sesame sensitivity among infants and children. Pediatr Allergy Immunol 2003;14(4):312-316. PubMed
- Moneret-Vautrin, D. A., Kanny, G., and Lagrange, A. [Occupational asthma caused by organic substances]. Rev Med Interne 1994;15 Suppl 2:216s-225s.
- Keskinen, H., Ostman, P., Vaheri, E., Tarvainen, K., Grenquist-Norden, B., Karppinen, O., and Nordman, H. A case of occupational asthma, rhinitis and urticaria due to sesame seed. Clin Exp Allergy 1991;21(5):623-624. PubMed
- Alday, E., Curiel, G., Lopez-Gil, M. J., Carreno, D., and Moneo, I. Occupational hypersensitivity to sesame seeds. Allergy 1996;51(1):69-70. DOI
- Kubo, Y., Nonaka, S., and Yoshida, H. Contact sensitivity to unsaponifiable substances in sesame oil. Contact Dermatitis 1986;15(4):215-217. PubMed
- Steurich, F. [Allergy to sesame seeds]. Pneumologie 1989;43(12):710-714.
- Morisset, M., Moneret-Vautrin, D. A., Kanny, G., Guenard, L., Beaudouin, E., Flabbee, J., and Hatahet, R. Thresholds of clinical reactivity to milk, egg, peanut and sesame in immunoglobulin E-dependent allergies: evaluation by double-blind or single-blind
- Tsai, H. J., Kumar, R., Pongracic, J., Liu, X., Story, R., Yu, Y., Caruso, D., Costello, J., Schroeder, A., Fang, Y., Demirtas, H., Meyer, K. E., O'Gorman, M. R., and Wang, X. Familial aggregation of food allergy and sensitization to food allergens: a fam
- James, C., Williams-Akita, A., Rao, Y. A., Chiarmonte, L. T., and Scheider, A. T. Sesame seed anaphylaxis. N Y State J Med 1991;91(10):457-458.
- Chiu, J. T. and Haydik, I. B. Sesame seed oil anaphylaxis. J Allergy Clin Immunol 1991;88(3 Pt 1):414-415. PubMed
- Asero, R., Mistrello, G., Roncarolo, D., Antoniotti, P. L., and Falagiani, P. A case of sesame seed-induced anaphylaxis. Allergy 1999;54(5):526-527.
- Pajno, G. B., Passalacqua, G., Magazzu, G., Barberio, G., Vita, D., and Canonica, G. W. Anaphylaxis to sesame. Allergy 2000;55(2):199-201. PubMed
- Neering, H., Vitanyi, B. E., Malten, K. E., van Ketel, W. G., and van Dijk, E. Allergens in sesame oil contact dermatitis. Acta Derm Venereol 1975;55(1):31-34. DOI
- Caminiti, L., Vita, D., Passalacqua, G., Arrigo, T., Barberi, S., Lombardo, F., and Pajno, G. B. Tahini, a little known sesame-containing food, as an unexpected cause of severe allergic reaction. J Investig Allergol Clin Immunol 2006;16(5):308-310.
- Phan, T. G., Strasser, S. I., Koorey, D., McCaughan, G. W., Rimmer, J., Dunckley, H., Goddard, L., and Adelstein, S. Passive transfer of nut allergy after liver transplantation. Arch Intern Med 2003;163(2):237-239. PubMed
- Oiso, N., Yamadori, Y., Higashimori, N., Kawara, S., and Kawada, A. Allergic contact dermatitis caused by sesame oil in a topical Chinese medicine, shi-un-ko. Contact Dermatitis 2008;58(2):109.
- VAN Dijk, E., Dijk, E., Neering, H., and Vitanyi, B. E. Contact hypersensitivity to sesame oil in patients with leg ulcers and eczema. Acta Derm Venereol 1973;53(2):133-135. DOI
- Beyer, K., Bardina, L., Grishina, G., and Sampson, H. A. Identification of sesame seed allergens by 2-dimensional proteomics and Edman sequencing: seed storage proteins as common food allergens. J Allergy Clin Immunol 2002;110(1):154-159. PubMed
- Koopman, M., Richter, C., Parren, R. J., and Janssen, M. Bodybuilding, sesame oil and vasculitis. Rheumatology (Oxford) 2005;44(9):1135. PubMed
- Kagi, M. K. and Wuthrich, B. Falafel burger anaphylaxis due to sesame seed allergy. Ann Allergy 1993;71(2):127-129.
- Hayakawa, R., Matsunaga, K., Suzuki, M., Hosokawa, K., Arima, Y., Shin, C. S., and Yoshida, M. Is sesamol present in sesame oil? Contact Dermatitis 1987;17(3):133-135.
- Malish, D., Glovsky, M. M., Hoffman, D. R., Ghekiere, L., and Hawkins, J. M. Anaphylaxis after sesame seed ingestion. J Allergy Clin Immunol 1981;67(1):35-38. PubMed
- Fremont, S., Zitouni, N., Kanny, G., Veneri, V., Metche, M., Moneret-Vautrin, D. A., and Nicolas, J. P. Allergenicity of some isoforms of white sesame proteins. Clin Exp Allergy 2002;32(8):1211-1215. PubMed
- Pastorello, E. A., Varin, E., Farioli, L., Pravettoni, V., Ortolani, C., Trambaioli, C., Fortunato, D., Giuffrida, M. G., Rivolta, F., Robino, A., Calamari, A. M., Lacava, L., and Conti, A. The major allergen of sesame seeds (Sesamum indicum) is a 2S albu
- Wolff, N., Cogan, U., Admon, A., Dalal, I., Katz, Y., Hodos, N., Karin, N., and Yannai, S. Allergy to sesame in humans is associated primarily with IgE antibody to a 14 kDa 2S albumin precursor. Food Chem Toxicol 2003;41(8):1165-1174. PubMed
- Wolff, N., Yannai, S., Karin, N., Levy, Y., Reifen, R., Dalal, I., and Cogan, U. Identification and characterization of linear B-cell epitopes of beta-globulin, a major allergen of sesame seeds. J Allergy Clin Immunol 2004;114(5):1151-1158.
- Navuluri, L., Parvataneni, S., Hassan, H., Birmingham, N. P., Kelly, C., and Gangur, V. Allergic and anaphylactic response to sesame seeds in mice: identification of Ses i 3 and basic subunit of 11s globulins as allergens. Int Arch Allergy Immunol 2006;14 PubMed
- Beyer, K., Grishina, G., Bardina, L., and Sampson, H. A. Identification of 2 new sesame seed allergens: Ses i 6 and Ses i 7. J Allergy Clin Immunol 2007;119(6):1554-1556. PubMed
- Moreno, F. J., Rubio, L. A., Olano, A., and Clemente, A. Uptake of 2S albumin allergens, Ber e 1 and Ses i 1, across human intestinal epithelial Caco-2 cell monolayers. J Agric Food Chem 2006;54(22):8631-8639. PubMed
- Moreno, F. J., Maldonado, B. M., Wellner, N., and Mills, E. N. Thermostability and in vitro digestibility of a purified major allergen 2S albumin (Ses i 1) from white sesame seeds (Sesamum indicum L.). Biochim Biophys Acta 2005;1752(2):142-153. PubMed
- Okura, T., Ibe, M., Umegaki, K., Shinozuka, K., and Yamada, S. Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. Biol Pharm Bull 2010;33(2):255-259. PubMed
- Nabekura, T., Yamaki, T., Ueno, K., and Kitagawa, S. Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals. Cancer Chemother Pharmacol 2008;62(5):867-873. PubMed
- Devarajan S, Chatterjee B, Urata H, et al. A blend of sesame and rice bran oils lowers hyperglycemia and improves the lipids. Am J Med. 2016;129(7):731-9. PubMed
- Khosravi-Boroujeni H, Nikbakht E, Natanelov E, Khalesi S. Can sesame consumption improve blood pressure? A systematic review and meta-analysis of controlled trials. J Sci Food Agric. 2017;97(10):3087-3094. PubMed
- Devarajan S, Singh R, Chatterjee B, Zhang B, Ali A. A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients. J Clin Lipidol. 2016;10(2):339-49. PubMed
- Warren CM, Chadha AS, Sicherer SH. Prevalence and severity of sesame allergy in the United States. JAMA Netw Open. 2019;2(8):e199144. PubMed
- Sillcox C, Gabrielli S, Clarke AE, et al. Sesame-induced anaphylaxis in pediatric patients from the cross-Canada anaphylaxis registry. Ann Allergy Asthma Immunol 2022;129(3):342-346. PubMed
- Yargholi A, Najafi MH, Zareian MA, Hawkins J, Shirbeigi L, Ayati MH. The effects of sesame consumption on glycemic control in adults: A systematic review and meta-analysis of randomized clinical trial. Evid Based Complement Alternat Med 2021;2021:2873534. PubMed
- Sohouli MH, Haghshenas N, Hernández-Ruiz Á, Shidfar F. Consumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta-analysis of controlled clinical trials. Phytot PubMed
- Atefi M, Entezari MH, Vahedi H, Hassanzadeh A. The effects of sesame oil on metabolic biomarkers: a systematic review and meta-analysis of clinical trials. J Diabetes Metab Disord 2022;21(1):1065-1080. PubMed
- Khani B, Bidgoli SR, Moattar F, Hassani H. Effect of sesame on sperm quality of infertile men. J Res Med Sci. 2013;18(3):184-7.
- Huang H, Zhou G, Pu R, Cui Y, Liao D. Clinical evidence of dietary supplementation with sesame on cardiovascular risk factors: An updated meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2022;62(20):5592-5602. PubMed
Bishop's Weed 8 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Kiistala R, Makinen-Kiljunen S, Heikkinen K, et al. Occupational allergic rhinitis and contact urticaria caused by bishop's weed (Ammi majus). Allergy 1999;54:635-9.
- Ossenkoppele PM, van der Sluis WG, van Vloten WA. [Phototoxic dermatitis following the use of Ammi majus fruit for vitiligo]. Ned Tijdschr Geneeskd 1991;135:478-80.
- Malhotra S, Bailey DG, Paine MF, Watkins PB. Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther 2001;69:14-23. PubMed
- Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
- Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
- Dollahite, J. W., Younger, R. L., and Hoffman, G. O. Photosensitization in cattle and sheep caused by feeding Ammi majus (greater Ammi; Bishop's-Weed). Am J Vet.Res 1978;39(1):193-197. DOI
- Kavli, G. and Volden, G. Phytophotodermatitis. Photodermatol. 1984;1(2):65-75.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC