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Dietary supplement

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release Ingredients & Drug Interactions

by Nature's Plus

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Herbal Actives Acai 600 mg/20% Polyphenols Extended Release against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, weight loss, energy and vitality.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Acai. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: acai, a tropical fruit extract standardized to 20% polyphenols, in a 600 mg dose per tablet. Polyphenols are natural plant compounds with antioxidant properties.

The tablet also contains several inactive ingredients (microcrystalline cellulose, di-calcium phosphate, hydroxypropyl methylcellulose, stearic acid, magnesium stearate, silica, Activessence, and pharmaceutical glaze) that help form and preserve the tablet.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Acai product and its label doesn't state a use — see Acai's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence that acai supplements work for the uses this product markets — aging skin, athletic performance, erectile dysfunction, or high cholesterol. The evidence for each of these is rated as insufficient, which means the research so far hasn't been strong enough to say whether acai actually helps.

The evidence, ingredient by ingredient Acai

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Acai is generally well tolerated when eaten as a food, but the safety profile of concentrated supplements at higher doses hasn't been well studied. For pregnancy and breastfeeding, there isn't enough data on acai supplements to know whether they're safe, so caution is advised — talk it over with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding before starting this product.

No adverse effects were documented in the data we hold.

Side effects, ingredient by ingredient Acai

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Acai.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — insulin, metformin, or any other blood sugar medication — run them through the search tool on this page and talk to your doctor or pharmacist before starting this acai supplement. Acai may interfere with how well those medications control your glucose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a single-ingredient acai supplement with no proven effectiveness for the conditions it lists. If you take antidiabetes medications, you need to clear it with your own doctor or pharmacist first because acai can affect blood sugar levels.

For pregnancy, breastfeeding, or any other questions about whether it's right for you, check in with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Herbal Actives Acai 600 mg/20% Polyphenols Extended Release, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467073067
Net contents 30 Tablet(s)
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 19924
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
097467073067
IngredientAmount% DV
Acai600 mg--

Other ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Hydroxypropyl Methylcellulose, Stearic Acid, Magnesium Stearate, Silica, Activessence, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

HYPO-ALLERGENIC

Precautions

Note: If you are pregnant or nursing, consult your health care professional before using any herbal product.

Do not use if either seal is missing or broken.

KEEP OUT OF REACH OF CHILDREN.

General Statements

THIS IS NOT A PRESCRIPTION PRODUCT. It is a dietary supplement made with the highest possible quality standards.

Printed HerbaShield inner seal and full bottle seal.

PRESCRIPTION QUALITY

Nutritional Support for Free Radical Defense.* Each Herbal Actives extended-release formula provides rapid and sustained results. Supplying the greatest concentration of active botanical principles, Herbal Actives Acai maximizes the synergistic benefits of the whole fruit, which naturally contains numerous flavonoids, including isovitexin, proanthocyanidins and anthocyanins. Guaranteed Maximum Potency: Each Herbal Actives formula is scientifically standardized to the highest level of active principles. HerbaShield: An exclusive purity and safety system providing light-resistant bottle, airtight inner seal, moisture-absorbing packet, tamper-evident safety cap and tamper-proof full bottle seal.

Brand IP Statement(s)

The Energy Supplements(R)

Activessence(R) is a registered trademark of InterActive Enzymes, a division of Triarco Industries, Inc. U.S. Patent Nos. 6,099,844 and 6,132,727.

(C)NATURAL ORGANICS(R)

Seals/Symbols

MAXIMUM POTENCY GUARANTEED(R)

GLUTEN Free

HerbaShield(R)

FDA Statement of Identity

Standardized Botanical Supplement

Formulation

VEGETARIAN

Free from artificial colors and preservatives.

Free from the common allergens yeast, wheat, soy and milk.

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement offering the consistent benefits of exact potency, one tablet daily or as recommended by your health care professional.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PRODUCT NO. 7306 LBL. 1129023

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Acai

Interacts with
86 drugs
600 mg per serving Form: Polyphenols

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacki...

Acai monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Hydroxypropyl Methylcellulose, Stearic Acid, Magnesium Stearate, Silica, Activessence, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus Drug Interactions

Want to check YOUR meds against Herbal Actives Acai 600 mg/20% Polyphenols Extended Release?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Acai 86

Individual Drug Interactions

The ingredients in Herbal Actives Acai 600 mg/20% Polyphenols Extended Release interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Herbal Actives Acai 600 mg/20% Polyphenols Extended Release interact with drugs. Each result below shows which ingredient is responsible. Acai

Each ingredient & the kinds of drugs it affects

For each ingredient in Herbal Actives Acai 600 mg/20% Polyphenols Extended Release with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Acai1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Preliminary clinical research in healthy adults has shown that taking acai may increase or decrease levels of fasting blood glucose.

Likelihood Possible Evidence D
Acai full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Herbal Actives Acai 600 mg/20% Polyphenols Extended Release, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd.
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus: Common Questions

Does Herbal Actives Acai 600 mg/20% Polyphenols Extended Release by Nature's Plus interact with any medications?
Yes. Based on its ingredients, Herbal Actives Acai 600 mg/20% Polyphenols Extended Release has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Herbal Actives Acai 600 mg/20% Polyphenols Extended Release contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is acai safe to take while pregnant?
There isn't enough safety data on acai supplements during pregnancy to say either way. Since you're planning to carry a baby, talk with your doctor or pharmacist about whether this product is right for you — they can weigh the limited data and help you make the best choice for your situation.
Can I use this while breastfeeding?
There isn't enough information on acai supplements during breastfeeding to know if it's safe. Check with your doctor or pharmacist before you start — they can give you personalized advice based on what you're nursing.
Does acai actually help with weight loss or cholesterol?
The research we have isn't strong enough to say it does. For weight loss and high cholesterol, both are rated insufficient evidence — meaning the data so far doesn't support a clear benefit from acai supplements.
What are polyphenols?
Polyphenols are natural compounds found in plants that act as antioxidants. This product is standardized to 20% polyphenols — that's just the way manufacturers ensure you get a consistent amount of these compounds in each dose.
Is there any risk from taking a concentrated acai supplement versus eating acai berries?
Acai berries as food are generally well tolerated, but concentrated supplements at higher doses haven't been well studied for safety. That's why the data advises caution — we know less about what happens when you take these pills than when you eat the fruit itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Herbal Actives Acai 600 mg/20% Polyphenols Extended Release is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release label
Go deeper

The Full Monographs Behind Herbal Actives Acai 600 mg/20% Polyphenols Extended Release’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Acai

Interacts with 86 drugs

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacking for the bold health claims often atta...

Read the full Acai monograph →
Sources

Sources & How We Checked

Herbal Actives Acai 600 mg/20% Polyphenols Extended Release's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Acai 2 references
  1. Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
  2. de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed

See these in context on the Acai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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