Herbal Iron Ingredients & Drug Interactions
by New Sun
What is this page for?
First and foremost: checking Herbal Iron against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Herbal Iron is a dietary supplement by New Sun with 9 active ingredients. Its ingredients are commonly taken for iron-deficiency anemia, low iron stores during pregnancy, fatigue from iron deficiency.Based on those ingredients, 1,192 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Beet, Celery, Stinging Nettle (root) Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Herbal Iron by New Sun
Ask about any prescription or over-the-counter medication and we check it for interactions with Herbal Iron by New Sun — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Herbal Iron by New Sun
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 1 of its 9 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (910 mg) without saying how much of each component you get.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 7 of the 7 matched ingredients can interact with medications — Burdock, Beet, Mullein, Yellow Dock, Stinging Nettle, among others.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
- For scale: 1,193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 7 of 7.
- General safety write-ups exist for 7 of 7.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 8 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Herbal Iron, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Herbal Iron by New Sun, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Iron | 0.5 mg | 2% |
| Mullein | 0 NP | -- |
| Proprietary Blend | 910 mg | -- |
| Burdock | 0 NP | -- |
| Yellow Dock | 0 NP | -- |
| Beet | 0 NP | -- |
| Celery | 0 NP | -- |
| Raspberry | 0 NP | -- |
| Stinging Nettle (root) Concentrate | 0 NP | -- |
| Celery | 0 NP | -- |
Other ingredients: Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or Poison Control Center immediately.
Do not use if pregnant.
Individuals withs kidney stones or renal disorders should use this product caustiosly.
If nursing, taking any medications, or experiencing health issues, consult your doctor before use.
Do not use if safety seal is missing or broken.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Recommendation: As a dietary supplement, take two capsules with meals twice daily.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure, or prevent any disease.
General
Product No. 50-5 V5.0
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Herbal Iron by New Sun label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Herbal Iron by New Sun
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Iron
Interacts with80 drugs
Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...
Iron monograph & interactionsProprietary Blend
- › Mullein
- › Burdock
- › Yellow Dock
- › Beet
- › Celery
- › Raspberry
- › Stinging Nettle (root) Concentrate
- › Celery
Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.
Herbal Iron by New Sun Drug Interactions
Herbal Iron contains 9 ingredients, and 7 of them have known drug interactions. Altogether they interact with 1,192 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Herbal Iron?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Herbal Iron interact with 1,192 drugs. Click any drug to see the details.
7 of the 9 ingredients in Herbal Iron interact with drugs. Each result below shows which ingredient is responsible. Beet Celery Stinging Nettle (root) Concentrate Mullein Burdock Iron Yellow Dock
MethyclothiazideAquatensen, Enduron
How Methyclothiazide interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Methyclothiazide interactionCeleryPhotosensitizing Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Methyclothiazide interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Methyclothiazide interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Methyclothiazide interactionMethyclothiazide, PargylineEutron
How Methyclothiazide, Pargyline interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Methyclothiazide, Pargyline interactionCeleryPhotosensitizing Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Methyclothiazide, Pargyline interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Methyclothiazide, Pargyline interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Methyclothiazide, Pargyline interactionMethyclothiazide, ReserpineDiutensen-R
How Methyclothiazide, Reserpine interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Methyclothiazide, Reserpine interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Methyclothiazide, Reserpine interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Methyclothiazide, Reserpine interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Methyclothiazide, Reserpine interactionMetolazoneDiulo, Mykrox, Zaroxolyn
How Metolazone interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Metolazone interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Metolazone interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Metolazone interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Metolazone interactionPolythiazideRenese
How Polythiazide interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Polythiazide interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Polythiazide interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Polythiazide interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Polythiazide interactionPolythiazide, PrazosinMinizide
How Polythiazide, Prazosin interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Polythiazide, Prazosin interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Polythiazide, Prazosin interactionCeleryPhotosensitizing Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Polythiazide, Prazosin interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Polythiazide, Prazosin interactionPolythiazide, ReserpineRenese R
How Polythiazide, Reserpine interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Polythiazide, Reserpine interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Polythiazide, Reserpine interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Polythiazide, Reserpine interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Polythiazide, Reserpine interactionQuinethazoneHydromox
How Quinethazone interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Quinethazone interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Quinethazone interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Quinethazone interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Quinethazone interactionQuinethazone, ReserpineHydromox R
How Quinethazone, Reserpine interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Quinethazone, Reserpine interactionCeleryPhotosensitizing Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Quinethazone, Reserpine interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Quinethazone, Reserpine interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Quinethazone, Reserpine interactionReserpine, TrichlormethiazideMetatensin #2, Metatensin #4, Naquival
How Reserpine, Trichlormethiazide interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Reserpine, Trichlormethiazide interactionCeleryAntihypertensive Drugs, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Reserpine, Trichlormethiazide interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Reserpine, Trichlormethiazide interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Reserpine, Trichlormethiazide interactionSacubitril, ValsartanEntresto
How Sacubitril, Valsartan interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Sacubitril, Valsartan interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Sacubitril, Valsartan interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Sacubitril, Valsartan interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Sacubitril, Valsartan interactionSpironolactoneAldactone, Carospir, Spiroton
How Spironolactone interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Spironolactone interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Spironolactone interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Spironolactone interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Spironolactone interactionTheobromineTheobromine
How Theobromine interacts with Herbal Iron — through 2 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Theobromine interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Theobromine interactionTorsemideDemadex, Soaanz
How Torsemide interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Torsemide interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Torsemide interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Torsemide interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Torsemide interactionTrichlormethiazideAq 4B Aquazide, Marazide II, Metahydrin, Naqua
How Trichlormethiazide interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Trichlormethiazide interactionCeleryPhotosensitizing Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery + Trichlormethiazide interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Trichlormethiazide interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Trichlormethiazide interactionUreaUreaphil
How Urea interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Urea interactionCeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Urea interactionStinging Nettle (root) ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle (root) Concentrate + Urea interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Urea interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
BeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Herbal Iron — through 3 ingredients. Tap an ingredient for the detail:
CeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Abciximab interactionBurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Abciximab interactionMulleinAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
BeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
BeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
BeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Herbal Iron — through 3 ingredients. Tap an ingredient for the detail:
BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Abrocitinib interactionCeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Abrocitinib interactionMulleinAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
BeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Herbal Iron — through 1 ingredient. Tap an ingredient for the detail:
Stinging Nettle (root) ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle (root) Concentrate + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Herbal Iron — through 2 ingredients. Tap an ingredient for the detail:
CeleryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery + Acebutolol interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Herbal Iron — through 3 ingredients. Tap an ingredient for the detail:
CeleryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery + Acenocoumarol interactionBurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Acenocoumarol interactionMulleinAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Herbal Iron — through 2 ingredients. Tap an ingredient for the detail:
CeleryAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery + Acetaminophen interactionBeetCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
CeleryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen, Aspirin interactionBurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Acetaminophen, Aspirin interactionBeetCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet + Acetaminophen, Aspirin interactionMulleinAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Herbal Iron — through 4 ingredients. Tap an ingredient for the detail:
CeleryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery + Acetaminophen, Aspirin, Caffeine interactionBeetCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet + Acetaminophen, Aspirin, Caffeine interactionBurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock + Acetaminophen, Aspirin, Caffeine interactionMulleinAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Herbal Iron — through 2 ingredients. Tap an ingredient for the detail:
CeleryAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionBeetCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Herbal Iron with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Beet
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.
Antihypertensive Drugs
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.
Celery
Anticoagulant/Antiplatelet Drugs
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Celery root contains the constituents falcarinol and falcarindiol. Laboratory research suggests that these constituents can inhibit platelet aggregation. This effect has not been reported in humans.
Antihypertensive Drugs
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Clinical research suggests that taking celery seed extract may reduce daytime systolic blood pressure by about 12 mmHg compared to less than 1 mmHg with placebo.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggests that constituents of celery can inhibit CYP1A2. This effect has not been reported in humans.
Levothyroxine (Synthroid, Others)
Theoretically, celery seed might decrease the effects of levothyroxine.
Several cases of hypothyroidism with low T4 levels have been reported in people who were previously stabilized on levothyroxine and then started taking celery seed tablets. They presented with symptoms such as lethargy, bloating, and dry skin, and recovered when celery seed was stopped. However, celery stem and leaf has been associated with case reports of hyperthyroidism in patients with no pre-existing thyroid disorders.
Lithium
Theoretically, celery might reduce excretion and increase levels of lithium due to potential diuretic effects.
Celery is thought to have diuretic properties. However, this effect has not been confirmed in humans.
Venlafaxine (Effexor)
Theoretically, celery root extract might increase blood levels of venlafaxine.
There is one case report of a patient who experienced medication-induced bipolar disorder after beginning to take celery root extract 1000 mg daily along with venlafaxine 75 mg and St. John's wort 600 mg daily. Symptoms included confusion, speech abnormalities, manic affect, and visual hallucinations. The plasma level of venlafaxine was 476.8 ng/mL (normal range 195-400 ng/mL). It is theorized that celery root increased venlafaxine levels by inhibiting cytochrome P450 2D6.
Acetaminophen (Tylenol, Others)
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Animal research suggests that concomitant use of celery juice plus acetaminophen prolongs the effects of acetaminophen. This effect has been attributed to a decrease in hepatic cytochrome P450 activity. However, other animal research shows that pretreatment with celery root extract protects against acetaminophen-induced acute liver failure. These effects have not been reported in humans.
Photosensitizing Drugs
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Laboratory research shows that celery contains photosensitizing agents such as phenols and psoralens.
Stinging Nettle (root) Concentrate
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Mullein
Anticoagulant/Antiplatelet Drugs
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.
Burdock
Anticoagulant/Antiplatelet Drugs
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.
Iron
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.
Bisphosphonates
Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.
Denosumab (Prolia, Others)
Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.
Dolutegravir (Tivicay)
Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.
Integrase Inhibitors
Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.
Levodopa
Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.
Levothyroxine (Synthroid, Others)
Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.
Methyldopa (Aldomet)
Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.
Mycophenolate Mofetil (Cellcept)
Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.
Penicillamine (Cuprimine, Depen)
Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.
Quinolone Antibiotics
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.
Tetracycline Antibiotics
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.
Chloramphenicol
Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.
Yellow Dock
Digoxin (Lanoxin)
Theoretically, yellow dock might increase the risk of digoxin toxicity when used long-term or in large amount.
When yellow dock is used chronically or in large amounts, hypokalemia may occur. This might increase the toxic effects of digoxin.
Diuretic Drugs
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
When yellow dock is used chronically or in large amounts, hypokalemia may occur, and overuse of yellow dock might compound diuretic-induced potassium loss.
Warfarin (Coumadin)
Theoretically, the laxative effects of yellow dock might increase the effects of warfarin, including the risk of bleeding.
The anthraquinones in yellow dock have a mild stimulant laxative effect. Consuming excessive amounts can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding.
Brand information
Manufacturer and brand details for Herbal Iron, from the product label.
New Sun
See all New Sun products- Name
- New Sun, Inc.
- City
- Hendersonville
- State
- NC
- ZipCode
- 28792
- Phone Number
- 1-800-544-0777
- Web Address
- www.newsun.net
Herbal Iron by New Sun: Common Questions
Does Herbal Iron by New Sun interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Herbal Iron’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Iron
Interacts with 80 drugsIron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...
Read the full Iron monograph → Herb & supplement monographMullein
Interacts with 122 drugsMullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...
Read the full Mullein monograph → Herb & supplement monographBurdock
Interacts with 122 drugsBurdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...
Read the full Burdock monograph → Herb & supplement monographYellow Dock
Interacts with 78 drugsYellow dock is a traditional herb used mostly as a mild laxative and a digestive and skin tonic. Good-quality human studies are lacking, so its benefits are largely unproven, and its natural...
Read the full Yellow Dock monograph → Herb & supplement monographBeet
Interacts with 861 drugsBeet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...
Read the full Beet monograph → Herb & supplement monographCelery
Interacts with 651 drugsCelery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement use...
Read the full Celery monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph →Sources & How We Checked
Herbal Iron's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 178 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iron 72 references
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- Ullen H, Augustsson K, Gustavsson C, Steineck G. Supplementary iron intake and risk of cancer: reversed causality? Cancer Lett 1997;114:215-6.
- Reunanen A, Takkunen H, Knekt P, et al. Body iron stores, dietary iron intake and coronary heart disease mortality. J Intern Med 1995;238:223-30. PubMed
- Lund EK, Wharf SG, Fairweather-Tait SJ, Johnson IT. Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers. Am J Clin Nutr 1999;69:250-5.
- Rehman A, Collis CS, Yang M, et al. The effects of iron and vitamin C co-supplementation on oxidative damage to DNA in healthy volunteers. Biochem Biophys Res Comm 1998;246:293-8. PubMed
- Klipstein-Grobusch K, Grobbee DE, den Breeijen JH, et al. Dietary iron and risk of myocardial infarction in the Rotterdam Study. Am J Epidemiol 1999;149:421-8. PubMed
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Campbell N, Paddock V, Sundaram R. Alteration of methyldopa absorption, metabolism, and blood pressure control by ferrous sulfate and ferrous gluconate. Clin Pharmacol Ther 1988;43:381-6..
- Schumann K, Borch-Iohnsen B, Hentze MW, Marx JJ. Tolerable upper intakes for dietary iron set by the US Food and Nutrition Board (commentary). Am J Clin Nutr 2002;76:499-500. PubMed
- Tuomainen TP, Punnonen K, Nyyssonen K, Salonen JT. Association between body iron stores and the risk of acute myocardial infarction in men. Circulation 1998;97:1461-6.. PubMed
- Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in Eastern Finnish men. Circulation 1992;86:803-11.. PubMed
- Campbell NRC, Hasinoff B. Ferrous sulfate reduces levodopa bioavailability: Chelation as a possible mechanism. Clin Pharmacol Ther 1989;45:220-5.. PubMed
- Campbell NRC, Hasinoff BB, Stalts H, et al. Ferrous sulfate reduces thyroxine efficacy in patients with hypothyroidism. Ann Int Med 1992;117:1010-3.. PubMed
- Kiechl S, Willeit J, Egger G, et al. Body iron stores and the risk of carotid atherosclerosis: prospective results from the Bruneck study. Circulation 1997;96:3300-07. PubMed
- Comparison of oral iron supplements. Pharmacist's Letter / Prescriber's Letter 2008;24(8):240811.
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- Toblli J. E., Brignoli, R. Iron(III)-hydroxide polymaltose complex in iron deficiency anemia / review and meta-analysis. Arzneimittelforschung 2007;57(6A):431-438. PubMed
- Köpcke W., Sauerland M. C. Meta-analysis of efficacy and tolerability data on iron proteinsuccinylate in patients with iron deficiency anemia of different severity. Arzneimittelforschung 1995;45(11):1211-1216.
- Campbell N. R., Campbell R. R., Hasinoff B. B. Ferrous sulfate reduces methyldopa absorption: methyldopa: iron complex formation as a likely mechanism. Clin Invest Med 1990;13(6):329-332.
- Morii M., Ueno K., Ogawa A., Kato R., Yoshimura H., Wada K., Hashimoto H., Takada M., Tanaka K., Nakatani T., Shibakawa M. Impairment of mycophenolate mofetil absorption by iron ion. Clin Pharmacol Ther 2000;68(6):613-616. PubMed
- Gelone D. K., Park J. M., Lake K. D. Lack of an effect of oral iron administration on mycophenolic acid pharmacokinetics in stable renal transplant recipients. Pharmacotherapy 2007;27(9):1272-1278. PubMed
- Ducray P. S., Banken L., Gerber M., Boutouyrie B., Zandt H. Absence of an interaction between iron and mycophenolate mofetil absorption. Br J Clin Pharmacol 2006;62(4):492-495. PubMed
- Lorenz M., Wolzt M., Weigel G., Puttinger H., Hörl W. H., Födinger M., Speiser W., Sunder-Plassmann G. Ferrous sulfate does not affect mycophenolic acid pharmacokinetics in kidney transplant patients. Am J Kidney Dis 2004;43(6):1098-1103. PubMed
- Osman M. A., Patel R. B., Schuna A., Sundstrom W. R., Welling P. G. Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate. Clin Pharmacol Ther 1983;33(4):465-470. PubMed
- Michael, B., Coyne, D. W., Fishbane, S., Folkert, V., Lynn, R., Nissenson, A. R., Agarwal, R., Eschbach, J. W., Fadem, S. Z., Trout, J. R., Strobos, J., and Warnock, D. G. Sodium ferric gluconate complex in hemodialysis patients: adverse reactions compar
- Zhang, X., Ouyang, J., Wieczorek, R., and DeSoto, F. Iron medication-induced gastric mucosal injury. Pathol.Res Pract 2009;205(8):579-581. PubMed
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- Liabeuf S, Gras V, Moragny J, et al. Ulceration of the oral mucosa following direct contact with ferrous sulfate in elderly patients: a case report and a review of the French National Pharmacovigilance Database. Clin Interv Aging. 2014 Apr 25;9:737-40. PubMed
- Qiao L, Feng Y. Intakes of heme iron and zinc and colorectal cancer incidence: a meta-analysis of prospective studies. Cancer Causes Control. 2013 Jun;24(6):1175-83. PubMed
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- Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents: Drug Interactions between Integrase Inhibitors and Other Drugs. AIDSinfo. July 14, 2016. Available at: https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescen
- Song I, Borland J, Arya N, Wynne B, Piscitelli S. Pharmacokinetics of dolutegravir when administered with mineral supplements in healthy adult subjects. J Clin Pharmacol. 2015;55(5):490-6. PubMed
- Esan MO, Boele van Hensbroek M, Nkhoma E, et al. Iron supplementation in HIV infected Malawian children with anemia: a double-blind, randomized, controlled trial. Clin Inf Dis 2013;57(11):1626-34.doi:10.1093/cid/cit528. PubMed
- Zlotkin S, Newton S, Aimone AM, et al. Effect of iron fortification on malaria incidence in infants and young children in Ghana: a randomized trial. JAMA 2013;310(9):938-47. PubMed
- Khambalia AZ, Aimone A, Nagubandi P, et al. High maternal iron status, dietary iron intake and iron supplement use in pregnancy and risk of gestational diabetes mellitus: a prospective study and systematic review. Diabet Med. 2016;33(9):1211-21. PubMed
- Kinnunen TI, Luoto R, Helin A, Hemminki E. Supplemental iron intake and the risk of glucose intolerance in pregnancy: re-analysis of a randomised controlled trial in Finland. Matern Child Nutr. 2016;12(1):74-84.
- Low MS, Speedy J, Styles CE, De-Regil LM, Pasricha SR. Daily iron supplementation for improving anaemia, iron status and health in menstruating women. Cochrane Database Syst Rev. 2016;4:CD009747. PubMed
- Melit LE, Marginean CO, Mocanu S, Marginean MO. A rare case of iron-pill induced gastritis in a female teenager: A case report and a review of the literature. Medicine (Baltimore). 2017;96(30):e7550. PubMed
- Neuberger A, Okebe J, Yahav D, Paul M. Oral iron supplements for children in malaria-endemic areas. Cochrane Database Syst Rev. 2016;2:CD006589. PubMed
- Peña-Rosas JP, De-Regil LM, Gomez Malave H, Flores-Urrutia MC, Dowswell T. Intermittent oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2015;(10):CD009997. PubMed
- Brabin B, Gies S, Roberts SA, et al. Excess risk of preterm birth with periconceptional iron supplementation in a malaria endemic area: analysis of secondary data on birth outcomes in a double blind randomized controlled safety trial in Burkina Faso. Mala PubMed
- Kaundal R, Bhatia P, Jain A, et al. Randomized controlled trial of twice-daily versus alternate-day oral iron therapy in the treatment of iron-deficiency anemia. Ann Hematol 2020;99(1):57-63. PubMed
- Li N, Zhao G, Wu W, et al. The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: A randomized clinical trial. JAMA Netw Open. 2020;3(11):e2023644.<br> PubMed
- Houston BL, Hurrie D, Graham J, et al. Efficacy of iron supplementation on fatigue and physical capacity in non-anaemic iron-deficient adults: a systematic review of randomised controlled trials. BMJ Open. 2018;8(4):e019240. PubMed
- Koch RM, Tchernodrinski S, Principe DR. Case report: Rapid onset, ischemic-type gastritis after initiating oral iron supplementation. Front Med (Lausanne) 2022;9:1010897. PubMed
- Milman NT. Iron supplementation in pregnant Danish women revisited: Effects on prepartum and postpartum iron deficiency, anemia, serum erythropoietin; including iron status, erythropoietin and anthropometrics in newborns. A randomized, placebo-controlled
- Rogozinska E, Daru J, Nicolaides M, et al. Iron preparations for women of reproductive age with iron deficiency anaemia in pregnancy (FRIDA): a systematic review and network meta-analysis. Lancet Haematol 2021;8(7):e503-e512. PubMed
- Shah AA, Donovan K, Seeley C, et al. Risk of infection associated with administration of intravenous iron: A systematic review and meta-analysis. JAMA Netw Open 2021;4(11):e2133935. PubMed
- Gamad N, Saha PK, Sharma P, Suri V, Chakrabarti A, Saha L. A randomized controlled trial comparing the efficacy, tolerability, and cost of oral iron preparations in iron-deficiency anemia in pregnancy. J Obstet Gynaecol Res 2021;47(11):3828-3841. PubMed
- El-Hawy MA, Abd Al-Salam SA, Bahbah WA. Comparing oral iron bisglycinate chelate, lactoferrin, lactoferrin with iron and iron polymaltose complex in the treatment of children with iron deficiency anemia. Clin Nutr ESPEN 2021;46:367-371. PubMed
- Adams A, Scheckel B, Habsaoui A, et al. Intravenous iron versus oral iron versus no iron with or without erythropoiesis- stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta-analysis. Cochrane Database Syst Rev 2 PubMed
- Kancherla K, Constantin H, Kanawati A, Graham E. Iron-induced Hypophosphatemic Osteomalacia-An Atypical Case of Bilateral Femoral Stress Fractures. J Am Acad Orthop Surg Glob Res Rev 2023;7(5):e22. PubMed
- Shi R, Marin JG, Beaulieu M. Skin staining following intravenous iron extravasation in a patient with chronic kidney disease: A case report. Can J Kidney Health Dis 2023;10:20543581231165705. PubMed
- Varandas C, Vieira J, Correia CJ, et al. Hypersensitivity reactions to iron products: 10-year experience in a Portuguese tertiary Centre. Eur Ann Allergy Clin Immunol 2023.
- Jara Vidal M, López García MC, Quílez Toboso RP. Kounis syndrome after intravenous iron administration. Med Clin (Barc) 2023. DOI
- Jara Vidal M, Ruiz de Assín Valverde A, Aznar Rodríguez S. Severe hypophospathemia secondary to intravenous iron. Med Clin (Barc) 2023. DOI
- Samões B, Silva B, Martins A, et al. Hypophosphatemic osteomalacia induced by intravenous iron therapy: a case report. Joint Bone Spine 2023;90(5):105586. PubMed
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