Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Herbal Supplement Ingredients & Drug Interactions

by Healthy For Life

Herbal Supplement label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Herbal Supplement against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Herbal Supplement is a dietary supplement by Healthy For Life with 5 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,232 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Slippery Elm, organic or wildcrafted Cat's Claw, organic Chinese Rhubarb. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Herbal Supplement by Healthy For Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Herbal Supplement by Healthy For Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Herbal Supplement by Healthy For Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (18 mg) without saying how much of each component you get.

This liquid supplement contains five active herbal ingredients: organic slippery elm, organic burdock, organic sheep sorrel, organic Chinese rhubarb, and organic or wildcrafted cat's claw. Slippery elm's inner bark is a demulcent — a soothing substance traditionally used for the throat and digestive tract.

Burdock root is a common food and traditional botanical. Sheep sorrel is a plant with a tart flavor, used in herbal preparations.

Chinese rhubarb root is a stimulant laxative with traditional use for bowel regularity. Cat's claw is a vine from Central and South America with a long history in herbal medicine.

The product also contains purified water as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Menopausal symptoms — rated "Possibly Effective" (Rhubarb) (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Rhubarb) (Natural Medicines).

The evidence for what these ingredients actually do is sparse. Slippery elm, burdock, and sheep sorrel all lack reliable evidence to rate their effectiveness for the conditions they're traditionally used for — including inflammatory bowel disease, skin conditions, cough, and bronchitis.

Chinese rhubarb shows possibly effective evidence for menopausal symptoms and pancreatitis, but insufficient evidence for constipation despite its laxative reputation. Cat's claw has insufficient evidence for the many conditions it's marketed for, from allergies and asthma to cancer and chronic fatigue.

In short, the science backing this blend's claimed benefits hasn't been established.

The evidence, ingredient by ingredient Slippery Elm Burdock Sorrel Rhubarb Cat's Claw

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited. It can cause contact dermatitis or urticaria (hives) in people sensitive to it or its pollen.

Burdock is likely safe as a food, though serious allergic reactions including anaphylaxis are rare. A case of liver injury has been reported with burdock-containing products, though it's unclear whether burdock alone was responsible.

Sheep sorrel is generally safe in food amounts but carries high oxalates; concentrated doses risk kidney damage — one case of kidney inflammation occurred in a young person who consumed wild sorrel. Rhubarb root commonly causes cramping, diarrhea, nausea, and vomiting and should not be used long-term; chronic overuse can deplete potassium and damage the kidneys.

Cat's claw is generally well tolerated short-term in healthy adults, though one clinical study reported anemia in 12% of participants and blood cell abnormalities in smaller numbers. Several case reports link cat's claw to kidney injury.

During pregnancy, burdock and rhubarb are considered possibly unsafe — avoid medicinal amounts. Sheep sorrel is rated possibly safe in pregnancy, but concentrated amounts haven't been proven safe.

Cat's claw is considered possibly unsafe in pregnancy due to its traditional use as an abortifacient. While breastfeeding, there isn't enough safety data for slippery elm, burdock, sheep sorrel, or cat's claw; medicinal amounts of rhubarb are best avoided since laxative compounds may pass into breast milk.

Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Slippery Elm Burdock Sorrel Rhubarb Cat's Claw

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Burdock, Rhubarb, Cat's Claw, Sorrel, Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; heart-rhythm medications.
  • For scale: 2,233 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin) — all five ingredients pose a theoretical bleeding risk. If you take blood pressure medications (antihypertensives) or calcium channel blockers, cat's claw and rhubarb may lower your pressure further.

Water pills (diuretics), corticosteroids, and heart medications like digoxin are at risk of potassium depletion from rhubarb overuse. Transplant patients on cyclosporine should know rhubarb may reduce its levels.

Patients taking CYP3A4-metabolized drugs — including Paxlovid — and those on immunosuppressants should also discuss this with their provider. Slippery elm may slow absorption of oral medications generally.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement combines five herbs with little established evidence of effectiveness and multiple documented interactions with common medications. If you take blood thinners, blood pressure drugs, water pills, heart or liver medications, or drugs metabolized by your liver, you should check with your own doctor or pharmacist before starting it.

The same goes if you're pregnant, breastfeeding, or have a history of kidney or liver problems. A healthcare provider familiar with your full medication list is the right person to guide whether this product is appropriate for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Herbal Supplement, straight from the product label.

Brand Healthy For Life
Barcode (UPC) 852225002044
Net contents 946 mL; 32 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218014
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Herbal Supplement by Healthy For Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
29.5 mL
Maximum serving Sizes:
29.5 mL
Servings per container
32
UPC/BARCODE
852225002044
IngredientAmount% DV
Proprietary Blend18 mg--
organic Slippery Elm0 NP--
organic Burdock0 NP--
organic Sheep Sorrel0 NP--
organic Chinese Rhubarb0 NP--
organic or wildcrafted Cat's Claw0 NP--

Other ingredients: purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non-gmo Gluten free

GMP

Gentle daily cleanser

Made with organic herbs

The herbs are used to cleanse body tissue, strengthen immune system, cleanse intestinal tract, reduce fatigue, improve skin health and increase circulation.

General Statements

Helping people for 20 years

Nutrition made simple

Healthy For Life is dedicated to helping people achieve better health. Our product provide essential nutrients often missing from our modern diet and are made with the highest quality organic ingredients.

The Healthy for Life Program 1 Omega 3-6-9 Replenish 2 Mineral Supplement Nutrition

How these herbs help you Our exclusive combination of herbs is based on an Indian formula that has been effective for over 100 year.

Whole foods + Healthy for Life = Good nutrition

FDA Statement of Identity

Dietary Supplement

Formula

3 Herbal Supplement Cleanse

FDA Disclaimer Statement

These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions for use: Take 1 fluid ounce (2 tablespoons) daily. This product should be used within 30 days after opening. Discard product after 30 days after opening. 1 Once daily

Seals/Symbols

Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Herbal Supplement by Healthy For Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Herbal Supplement label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Herbal Supplement by Healthy For Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size29.5 mL Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Herbal Supplement by Healthy For Life Drug Interactions

Want to check YOUR meds against Herbal Supplement?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,232Drugs
2,232 Moderate

Ingredients driving the most interactions

organic Slippery Elm 2,022
organic or wildcrafted Cat's Claw 962
organic Chinese Rhubarb 658
organic Sheep Sorrel 169
organic Burdock 122

Individual Drug Interactions

The ingredients in Herbal Supplement interact with 2,232 drugs. Click any drug to see the details.

5 of the 5 ingredients in Herbal Supplement interact with drugs. Each result below shows which ingredient is responsible. organic Slippery Elm organic or wildcrafted Cat's Claw organic Chinese Rhubarb organic Sheep Sorrel organic Burdock

Each ingredient & the kinds of drugs it affects

For each ingredient in Herbal Supplement with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
organic Slippery Elm full monograph & interactions

organic or wildcrafted Cat's Claw6 drug types · 962 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cat's claw may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Cat's claw contains rhynchophylline and isorhynchophylline. Animal research suggests that these alkaloids can inhibit platelet aggregation. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking cat's claw with antihypertensive drugs might increase the risk of hypotension.
Cat's claw contains rhynchophylline. In vitro and animal research suggests that rhynchophylline can lower blood pressure. This interaction has not been reported in humans.

Likelihood Probable Evidence D
Calcium Channel Blockers

Theoretically, taking cat's claw with calcium channel blockers might increase the risk of hypotension.
Cat's claw contains various alkaloids, including rhynchophylline, isorhynchophylline, corynoxeine, and isocorynoxiene. Animal research suggests that these alkaloids can lower blood pressure by acting as calcium channel blockers. This interaction has not been reported in humans.

Likelihood Probable Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cat's claw might increase or decrease the levels and effects of drugs metabolized by CYP3A4.
Cat's claw may affect the clearance of drugs metabolized by CYP3A4. In vitro research shows that cat's claw can inhibit CYP3A4 enzymes. In one case report, a patient taking cat's claw (at an unspecified dose) experienced increased serum levels of atazanavir, ritonavir, and saquinavir, all of which are CYP3A4 substrates. Levels returned to normal 15 days after discontinuation of the cat's claw supplement, suggesting inhibition of CYP3A4 by cat's claw. In contrast, animal research suggests that rhynchophylline, an alkaloid contained in cat's claw, induces CYP3A expression and accelerates the metabolism of nirmatrelvir, the active component in the nirmatrelvir/ritonavir combination product.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, cat's claw might interfere with immunosuppressive therapy.
In human and laboratory research, cat's claw has been shown to have immunostimulating activity. It stimulates phagocytosis and increases respiratory cellular activity and the mobility of leukocytes. Theoretically, this could interfere with the activity of immunosuppressant medications.

Likelihood Possible Evidence D
Nirmatrelvir/Ritonavir (Paxlovid)

Theoretically, cat's claw may decrease the levels of nirmatrelvir.
Cat's claw contains rhynchophylline. Animal research suggests that this alkaloid induces CYP3A expression, thereby accelerating the metabolism of nirmatrelvir, the active component in the nirmatrelvir/ritonavir combination product. This interaction has not been reported in humans.

Likelihood Possible Evidence D
organic or wildcrafted Cat's Claw full monograph & interactions

organic Chinese Rhubarb8 drug types · 658 drugs

Corticosteroids

Theoretically, frequent and high doses of rhubarb might increase the risk of hypokalemia when taken with corticosteroids.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might compound corticosteroid-induced potassium loss.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, taking rhubarb with cyclosporine might reduce cyclosporine levels.
Animal research shows that co-administration of rhubarb decoction 0.25 or 1 gram/kg with cyclosporine 2.5 mg/kg, decreases cyclosporine maximum plasma concentration and overall exposure levels when compared with taking cyclosporine alone. The authors theorize that rhubarb might reduce cyclosporine bioavailability by inducing of P-glycoprotein and/or cytochrome P450 3A4. However, since rhubarb was administered as a single oral dose and enzyme induction usually occurs after multiple doses, it is possible that cyclosporine absorption was actually reduced via rhubarb's stimulant laxative effects. Also, the composition of the rhubarb decoction was not described.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, overuse of rhubarb might increase the risk of adverse effects when taken with digoxin.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might cause potassium depletion, increasing the risk of digoxin toxicity.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, frequent and high doses of rhubarb might increase the risk of hypokalemia.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might cause potassium depletion and compound diuretic-induced potassium loss.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Some animal research suggests that anthraquinones in rhubarb might have hepatotoxic effects. Also, rhubarb use has been linked to at least 24 cases of liver injury, although details on the dose of rhubarb and duration of use in these cases is unclear.

Likelihood Possible Evidence D
Nephrotoxic Drugs

Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
The anthraquinone constituents of rhubarb have been shown to induce nephrotoxicity in animal research. Additionally, in a case report, a 23-year old female presented with kidney failure after taking 6 tablets of a proprietary slimming agent (found to contain the anthraquinones emodin and aloe-emodin from rhubarb) daily for 6 weeks and then adding diclofenac 25 mg 4 times daily for 2 days. The authors postulate that the anthraquinone constituents of rhubarb contributed to the renal dysfunction, and the addition of diclofenac, a nephrotoxic drug, led to renal failure. Until more is known, advise patients to avoid taking rhubarb if they are taking other potentially nephrotoxic drugs.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, rhubarb might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Rhubarb has stimulant laxative effects. Concomitant use with stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, excessive use of rhubarb might increase the risk of bleeding when taken with warfarin.
Rhubarb has stimulant laxative effects and can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of rhubarb.

Likelihood Possible Evidence D
organic Chinese Rhubarb full monograph & interactions

organic Sheep Sorrel3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
organic Sheep Sorrel full monograph & interactions

organic Burdock1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
organic Burdock full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Herbal Supplement, from the product label.

Healthy For Life

See all Healthy For Life products
Name
Healthy For Life
City
Des Moines
State
IA
ZipCode
50322
Phone Number
877-535-6158
Web Address
www.HealthyForLifeUSA.com
Pharmacist Counseling Corner

Herbal Supplement by Healthy For Life: Common Questions

Does Herbal Supplement by Healthy For Life interact with any medications?
Yes. Based on its ingredients, Herbal Supplement has a known interaction with 2,232 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Herbal Supplement contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my digestive upset?
Slippery elm and burdock are traditionally used for digestive complaints, but we don't have reliable evidence they actually work. Rhubarb is a stimulant laxative and does cause bowel movements, though it often comes with cramping and discomfort. Talk to your pharmacist about what's causing your symptoms — they can suggest something more established.
Is this safe if I'm pregnant?
No. Burdock and rhubarb are considered possibly unsafe during pregnancy, and cat's claw is also possibly unsafe — it has a history of use as an abortifacient. Sheep sorrel is rated possibly safe, but concentrated amounts haven't been tested. Don't take medicinal amounts of this product while pregnant; talk with your doctor or pharmacist for guidance.
Can I take this while breastfeeding?
There isn't enough safety data for slippery elm, burdock, sheep sorrel, or cat's claw while breastfeeding, and medicinal rhubarb is best avoided because laxative compounds can pass into milk. Discuss this product with your doctor or pharmacist to see if it's appropriate for you right now.
What's the rhubarb in here for?
Rhubarb root is a stimulant laxative — it makes you have a bowel movement. It does come with side effects like cramping and diarrhea, and it shouldn't be used long-term because overuse can deplete potassium and harm your kidneys.
Does cat's claw actually boost immunity?
Cat's claw hasn't been proven effective for the conditions it's marketed for, including immunity or chronic fatigue. Laboratory research shows it can stimulate immune activity, but that doesn't necessarily mean it works or is safe in people — and it poses risks with certain medications.
Are there any fillers in this?
The only inactive ingredient listed is purified water. The five active herbs make up the bulk of what you're taking.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Herbal Supplement is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Herbal Supplement label
Go deeper

The Full Monographs Behind Herbal Supplement’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph → Herb & supplement monograph

Sorrel

Interacts with 169 drugs

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its hig...

Read the full Sorrel monograph → Herb & supplement monograph

Rhubarb

Interacts with 658 drugs

Rhubarb root has a long history of use as a laxative and in traditional Chinese medicine, and its edible stalks are a common food. Most medicinal claims are backed by limited or low-quality...

Read the full Rhubarb monograph → Herb & supplement monograph

Cat's Claw

Interacts with 962 drugs

Cat's claw is a South American vine traditionally used for inflammation, joint pain, and immune support. Some small studies hint it may help with arthritis symptoms, but the overall evidence...

Read the full Cat's Claw monograph →
Sources

Sources & How We Checked

Herbal Supplement's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 58 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
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Rhubarb 20 references
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Cat's Claw 16 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
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See these in context on the Cat's Claw monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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