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Dietary supplement

Horny Goat Weed & Maca Vanilla Flavor Ingredients & Drug Interactions

by TerraVita

Horny Goat Weed & Maca Vanilla Flavor label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Horny Goat Weed & Maca Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Horny Goat Weed & Maca Vanilla Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for erectile dysfunction, low libido, fatigue and low energy.Based on those ingredients, 965 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed And Maca Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Horny Goat Weed & Maca Vanilla Flavor by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Horny Goat Weed & Maca Vanilla Flavor by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Horny Goat Weed & Maca Vanilla Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Horny Goat Weed And Maca Glycerite Liquid Extract” is listed as a grouped ingredient — the label gives one combined amount (0.13 mg) without saying how much of each component you get.

This product has 2 active ingredients: Maca Glycerite Liquid Extract and Horny Goat Weed Glycerite Liquid Extract. Maca is a root traditionally used to support fertility, energy, and mood; horny goat weed is an herb used to support sexual function and circulation.

The product comes in liquid extract form with glycerin and vanilla flavoring as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for both ingredients is insufficient to rate. We don't have established data showing that maca works for amenorrhea, anemia, sexual dysfunction, athletic performance, or bone health — but that doesn't mean it doesn't; we simply lack reliable human studies.

The same applies to horny goat weed for sexual dysfunction, bronchitis, heart disease, or osteoporosis. If you're considering this product for a specific condition, that gap in evidence is worth discussing with your pharmacist.

The evidence, ingredient by ingredient Horny Goat Weed Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both maca and horny goat weed are generally well tolerated in the short term, though long-term supplement safety hasn't been studied thoroughly. With horny goat weed, the most common side effects are dizziness, dry mouth, nosebleed, thirst, and vomiting; respiratory arrest has been reported rarely.

Maca from uncooked sources may cause stomach pain. Pregnancy: maca has insufficient data — talk to your doctor or pharmacist before using it.

Horny goat weed is considered possibly unsafe in pregnancy. Neither ingredient has enough data on breastfeeding safety; avoid or discuss with your healthcare provider.

Side effects, ingredient by ingredient Horny Goat Weed Maca

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Horny Goat Weed.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 966 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this, double-check with your pharmacist if you use blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel), blood pressure medications, estrogen or birth control, or any drug that your liver processes (your pharmacist can help identify those). Horny goat weed may increase side effects or change how these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for adults interested in fertility and sexual function support, but the evidence for either ingredient is still emerging. If you take blood thinners, blood pressure medications, estrogen therapy, or drugs processed through your liver, check with your pharmacist first — interactions are possible.

Pregnant or breastfeeding? Skip it and talk to your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Horny Goat Weed & Maca Vanilla Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435225896
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 281439
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Horny Goat Weed & Maca Vanilla Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435225896
IngredientAmount% DV
Maca Glycerite Liquid Extract0 NP--
Horny Goat Weed And Maca Glycerite Liquid Extract0.13 mg--
Horny Goat Weed Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin, Vanilla flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5) Vanilla flavored

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Horny Goat Weed & Maca Vanilla Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Horny Goat Weed & Maca Vanilla Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Horny Goat Weed & Maca Vanilla Flavor by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Horny Goat Weed And Maca Glycerite Liquid Extract

Interacts with
965 drugs
0.13 mg per serving

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these...

Horny Goat Weed And Maca Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Vanilla flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Horny Goat Weed & Maca Vanilla Flavor by TerraVita Drug Interactions

Want to check YOUR meds against Horny Goat Weed & Maca Vanilla Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
965Drugs
965 Moderate

Ingredients driving the most interactions

Horny Goat Weed And Maca Glycerite Liquid Extract 965

Individual Drug Interactions

The ingredients in Horny Goat Weed & Maca Vanilla Flavor interact with 965 drugs. Click any drug to see the details.

1 of the 1 ingredient in Horny Goat Weed & Maca Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed And Maca Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Horny Goat Weed & Maca Vanilla Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed And Maca Glycerite Liquid Extract6 drug types · 965 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed And Maca Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Horny Goat Weed & Maca Vanilla Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Horny Goat Weed & Maca Vanilla Flavor by TerraVita: Common Questions

Does Horny Goat Weed & Maca Vanilla Flavor by TerraVita interact with any medications?
Yes. Based on its ingredients, Horny Goat Weed & Maca Vanilla Flavor has a known interaction with 965 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Horny Goat Weed & Maca Vanilla Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm trying to get pregnant?
Maca doesn't have enough data to know whether it's safe or helps with fertility in supplement amounts — there's insufficient evidence either way. Horny goat weed is considered possibly unsafe in pregnancy. Talk to your doctor before starting, especially if you're planning pregnancy or already pregnant.
Is it safe to breastfeed while using this?
Neither ingredient has enough reliable safety data on breastfeeding. The safety notes advise against use while breastfeeding. Discuss this with your doctor or pharmacist to weigh your options.
What are the side effects I might notice?
With horny goat weed, some people report dizziness, dry mouth, nosebleed, thirst, or vomiting — especially with longer-term use. Maca from uncooked sources may cause stomach pain. Most people tolerate it short-term, but quality varies between products.
Does this actually work for sexual dysfunction?
We don't have reliable evidence yet that either maca or horny goat weed helps sexual dysfunction. The data is insufficient to rate, so we can't say one way or the other based on human studies.
I'm on birth control. Can I still take this?
Horny goat weed may increase estrogen effects, including the effects of birth control. Talk to your pharmacist before adding this to make sure it won't interfere with your contraception.
Can I use this long-term?
Horny goat weed hasn't been studied for long-term safety — short-term use is tolerated, but we don't know what happens with months or years of use. Maca also lacks long-term supplement safety data. This is worth discussing with your pharmacist if you're planning to use it ongoing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Horny Goat Weed & Maca Vanilla Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Horny Goat Weed & Maca Vanilla Flavor label
Go deeper

The Full Monographs Behind Horny Goat Weed & Maca Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horny Goat Weed

Interacts with 965 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph → Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph →
Sources

Sources & How We Checked

Horny Goat Weed & Maca Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Horny Goat Weed 11 references
  1. Cirigliano MD, Szapary PO. Horny goat weed for erectile dysfunction. Alt Med Alert 2001;4:19-22.
  2. Partin JF, Pushkin YR. Tachyarrhythmia and hypomania with horny goat weed. Psychosomatics 2004;45:536-7. PubMed
  3. De Naeyer A, Pocock V, Milligan S, De Keukeleire D. Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum. Fitoterapia 2005;76:35-40. PubMed
  4. Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
  5. Yap SP, Shen P, Li J, et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacol 2007;113:218-24. PubMed
  6. Yan, F. F., Liu, Y., Liu, Y. F., and Zhao, Y. X. Herba Epimedii water extract elevates estrogen level and improves lipid metabolism in postmenopausal women. Phytother.Res. 2008;22(9):1224-1228. PubMed
  7. Ramanathan VS, Mitropoulos E, Shlopov B, et al. An Enzyte'ing' case of acute hepatitis. J Clin Gastroenterol 2011;45(9):834-5. PubMed
  8. Zhong Q, Shi Z, Zhang L, et al. The potential of Epimedium koreanum Nakai for herb-drug interaction. J Pharm Pharmacol 2017;69(10):1398-408. doi: 10.1111/jphp.12773.
  9. Irfan M, Kwon TH, Lee DH, et al. Antiplatelet and Antithrombotic Effects of Epimedium koreanum Nakai. Evid Based Complement Alternat Med. Apr 2021;2021:7071987. PubMed
  10. Tan K, Yang W, Pang L, Hou F. Differences in clinical characteristics among 726 patients with Chinese herbal medicine- or Western medicine-induced liver injury. Medicine (Baltimore) 2022;101(32):e29909. PubMed
  11. Li K, Yu XH, Maskey AR, et al. Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid. Front Pharmacol 2023;13:1042756. PubMed

See these in context on the Horny Goat Weed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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