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Dietary supplement

Huai Hua Mi Ingredients & Drug Interactions

by Hawaii Pharm

Huai Hua Mi label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Huai Hua Mi against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Huai Hua Mi is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for supporting blood vessel and capillary health, bleeding-related complaints (traditional use), source of the flavonoid rutin.Based on those ingredients, 29 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sophora japonica Bud, Flower Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Huai Hua Mi by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Huai Hua Mi by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Huai Hua Mi by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Huai Hua Mi contains one active ingredient: sophora japonica bud and flower extract, derived from the pagoda tree. This extract has been used in traditional medicine, though modern human safety data are limited.

The liquid form also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pagoda Tree product and its label doesn't state a use — see Pagoda Tree's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates pagoda tree flower for hemorrhoids and menopausal symptoms as insufficient—meaning the studies aren't solid enough to say whether it works. We can't tell you it will or won't help with either condition based on the data available.

The evidence, ingredient by ingredient Pagoda Tree

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pagoda tree flower itself is generally well tolerated when taken orally, and no adverse effects have been reported in the traditional use we have data on. However, a thorough safety evaluation hasn't been done.

The safety data advise against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those states. One important note: long-term use of pagoda tree seed (a different part of the plant than what's in this product) is possibly unsafe and has been associated with serious effects like swelling and, rarely, death.

This product uses the flower and bud, not the seed, but caution is warranted given the limited human safety data overall.

Side effects, ingredient by ingredient Pagoda Tree

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pagoda Tree.
  • The most serious interaction on file is rated Moderate.
  • For scale: 29 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take caffeine-containing medications or consume caffeine regularly through coffee, tea, or energy drinks, check with your own doctor or pharmacist before starting this product. The extract may slow how fast your body clears caffeine, potentially intensifying its effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Huai Hua Mi may be worth considering if you're interested in traditional pagoda tree use, but the evidence for hemorrhoids or menopausal symptoms isn't established. The main caution is its interaction with caffeine—if you drink coffee or take caffeine-containing medications, talk with your own doctor or pharmacist before starting.

Also avoid it during pregnancy or breastfeeding, and discuss it with your healthcare provider if you have ongoing health concerns or take regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Huai Hua Mi, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253628213
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 301687
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Huai Hua Mi by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253628213
IngredientAmount% DV
Sophora japonica Bud, Flower Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Sophora japonica

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Huai Hua Mi by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Huai Hua Mi label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Huai Hua Mi by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Sophora japonica Bud, Flower Extract, Dry

Interacts with
29 drugs
983 mg per serving Form: Sophora japonica Bud Extract, Dry, Sophora japonica Flower Extract, Dry

Pagoda Tree (Styphnolobium japonicum, also called the Japanese pagoda tree) is a traditional Asian medicinal plant best known as a natural source of t...

Sophora japonica Bud, Flower Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Huai Hua Mi by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Huai Hua Mi?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
29Drugs
29 Moderate

Ingredients driving the most interactions

Sophora japonica Bud, Flower Extract, Dry 29

Individual Drug Interactions

The ingredients in Huai Hua Mi interact with 29 drugs. Click any drug to see the details.

1 of the 1 ingredient in Huai Hua Mi interact with drugs. Each result below shows which ingredient is responsible. Sophora japonica Bud, Flower Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Huai Hua Mi with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sophora japonica Bud, Flower Extract, Dry1 drug type · 29 drugs

Caffeine

Theoretically, pagoda tree might reduce the clearance of caffeine.
Pagoda tree contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in pagoda tree.

Likelihood Possible Evidence D
Sophora japonica Bud, Flower Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Huai Hua Mi, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Huai Hua Mi by Hawaii Pharm: Common Questions

Does Huai Hua Mi by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Huai Hua Mi has a known interaction with 29 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Huai Hua Mi contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pagoda tree flower used for?
Pagoda tree flower has been used in traditional medicine for hemorrhoids and menopausal symptoms. However, we don't have strong modern evidence that it works for either of these—the research data are insufficient to say either way.
Can I take this while pregnant or breastfeeding?
The safety data advise against it. There isn't enough information to know whether it's safe during pregnancy or while breastfeeding, so talk with your doctor or pharmacist about what's right for you.
What's in this product besides the active ingredient?
The liquid contains alcohol, water, and glycerin, which are inactive ingredients used to preserve and suspend the extract.
Are there any side effects?
Pagoda tree flower is generally well tolerated, and no adverse effects have been reported. However, a complete safety evaluation hasn't been done, so unusual symptoms should prompt you to stop and speak with your doctor.
Is this the same as pagoda tree seed?
No—this product uses the flower and bud, not the seed. The seed is a different part of the plant and carries different safety concerns, particularly with long-term use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Huai Hua Mi label
Go deeper

The Full Monographs Behind Huai Hua Mi’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pagoda Tree

Interacts with 29 drugs

Pagoda Tree (Styphnolobium japonicum, also called the Japanese pagoda tree) is a traditional Asian medicinal plant best known as a natural source of the flavonoid rutin. While it has a long...

Read the full Pagoda Tree monograph →
Sources

Sources & How We Checked

Huai Hua Mi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pagoda Tree 2 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. Eur.J Clin.Pharmacol. 2011;67(4):347-353. PubMed

See these in context on the Pagoda Tree monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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