HyperAmino Fruit Punch Ingredients & Drug Interactions
What is this page for?
First and foremost: checking HyperAmino Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HyperAmino Fruit Punch is a dietary supplement by Gaspari Nutrition with 6 active ingredients. Its ingredients are commonly taken for antioxidant support, weight loss, heart health.Based on those ingredients, 1,402 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Green Tea extract, Guarana extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against HyperAmino Fruit Punch by Gaspari Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with HyperAmino Fruit Punch by Gaspari Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of HyperAmino Fruit Punch by Gaspari Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
HyperAmino Fruit Punch contains 15 ingredients total. The active amino acids are L-glutamine, L-tyrosine, L-isoleucine, L-valine, L-citrulline, L-arginine, L-threonine, L-lysine, L-phenylalanine, L-methionine, L-leucine, L-histidine, and micronized L-taurine.
These are branched-chain and other amino acids designed to support muscle recovery and performance. The product also includes green tea extract and guarana extract for energy and antioxidant support.
The remaining ingredients—natural and artificial flavor, citric acid, silicon dioxide, malic acid, sucralose, acesulfame-potassium, and FD&C Red #40 Lake—are inactive fillers, acids, and colorants that give the powder its taste and shelf stability.
Does it work?
Not established
The effectiveness data we hold is limited for most of this product's intended purpose. L-glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting and recovery from trauma or surgery.
L-tyrosine is effective for PKU (phenylketonuria, a rare genetic condition) and possibly effective for cognitive function and memory. L-phenylalanine shows possibly effective evidence for vitiligo but possibly ineffective for ADHD.
L-methionine is possibly effective for neural tube birth defects. Green tea extract is likely effective for HPV-related conditions and possibly effective for ovarian cancer and cholesterol.
The evidence isn't established in our data for several ingredients as to their effects on athletic performance, muscle recovery, or amino acid supplementation in healthy people.
How safe is it?
Well-documented data
L-glutamine is generally well tolerated in healthy adults but requires medical supervision in people with kidney or liver disease; pregnancy is rated likely safe, but breastfeeding data is insufficient. L-tyrosine is generally well tolerated but should only be used under healthcare provider guidance; pregnancy and breastfeeding data are insufficient.
L-phenylalanine should be avoided during pregnancy and breastfeeding due to lack of safety data, and must not be used by people with PKU. L-threonine and L-lysine have insufficient pregnancy and breastfeeding data.
L-methionine is likely safe in pregnancy and has insufficient breastfeeding data. L-histidine is likely safe in pregnancy with insufficient breastfeeding data.
Micronized taurine is likely safe in pregnancy; it occurs naturally in breast milk but supplement safety is not well studied. Green tea extract may rarely cause liver injury at high doses; caffeine passes into breast milk, so keep intake moderate and avoid high-dose extracts in pregnancy.
Guarana is high in caffeine and should be avoided in pregnancy; caffeine passes into breast milk. Common side effects across these ingredients include headache, nausea, diarrhea, and gastrointestinal upset.
Meds to double-check
Major interaction found
Check with your pharmacist before using HyperAmino if you take nadolol, atorvastatin, or ephedrine — these carry Major-severity interactions with green tea extract that can significantly reduce drug effectiveness or cause dangerous stimulant effects. Also double-check if you're on levodopa (L-phenylalanine and L-tyrosine can reduce its effect), any MAOI antidepressant (L-phenylalanine may trigger a blood pressure crisis), baclofen, thyroid hormone, seizure medications (valproate, felbamate, phenytoin, ethosuximide, carbamazepine), blood pressure drugs, lithium, or certain psychiatric medications like clozapine or fluvoxamine.
The caffeine in green tea and guarana is the culprit behind most seizure-medication interactions.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
HyperAmino may appeal to athletes and people recovering from illness or surgery who want amino acid and energy support. If you take nadolol, atorvastatin, levodopa, any seizure medication, or any blood pressure or psychiatric drug, check your specific medications before use—interactions here are serious.
People with PKU must avoid this product entirely. Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or have liver or kidney disease.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 10 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HyperAmino Fruit Punch, straight from the product label.
| Brand | Gaspari Nutrition |
|---|---|
| Barcode (UPC) | 646511024519 |
| Net contents | 10.58 Ounce(s); 300 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 227995 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HyperAmino Fruit Punch by Gaspari Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Glutamine | 0 NP | -- |
| L-Tyrosine | 0 NP | -- |
| L-Isoleucine, Micronized | 0 NP | -- |
| L-Valine, Micronized | 0 NP | -- |
| L-Citrulline, Micronized | 0 NP | -- |
| L-Arginine, Micronized | 0 NP | -- |
| L-Threonine, Micronized | 0 NP | -- |
| L-Lysine, Micronized | 0 NP | -- |
| L-Phenylalanine, Micronized | 0 NP | -- |
| L-Methionine, Micronized | 0 NP | -- |
| L-Leucine, Micronized | 0 NP | -- |
| L-Histidine, Micronized | 0 NP | -- |
| micronized L-Taurine | 0 NP | -- |
| Green Tea extract | 0 NP | -- |
| Guarana extract | 0 NP | -- |
| Hyperamino Amino Blend | 5 Gram(s) | -- |
| Amino Recovery Matrix | 0 NP | -- |
| Blood Flow & Performance Enhancement Matrix | 0 NP | -- |
| Essential Amino Matrix | 0 NP | -- |
| BCAA 2:1:1 Matrix | 0 NP | -- |
| Hyperamino Hyper Energy Matrix | 200 mg | -- |
Other ingredients: Natural and Artificial flavor, Citric Acid, Silicon Dioxide, Malic Acid, Sucralose, Acesulfame-Potassium, FD&C Red #40 Lake
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports lean muscle growth Powerful energizers with antioxidant support Enhances endurance & stamina Anti-catabolic & anti-corstiol effects
Made in the USA from domestic and international ingredients.
Energy Focus Recovery
Formula
Train longer & harder with HyperAmino HyperAmino is exactly what the name says it is - amino acids that drive insane energy. Gaspari Nutrition has taken powerful amino acids and then tweaked them with a cutting-edge energy technology so that it blasts you faster and lasts longer.
HyperAmino is a Gaspari Nutrition muscle & strength supplement designed to quench the "hard to please" athlete's thirst!
HyperAmino includes rapid release energy aids alongside extended release energy components to provide an exceptionally quick, long-lasting, no-crash stimulant feeling that is in a "league of its own" when it comes to energized recovery! HyperAmino is an incredible breakthrough in BCAA and recovery enhancement.
Complete amino acid & energy fuel
Fruit Punch naturally & artificially flavored
Suggested/Recommended/Usage/Directions
Designed to be used before, during and after training, HyperAmino helps kick-start protein synthesis which plays an important role in muscle growth and recovery. Directions: Add 1 scoop of HyperAmino to 4-10oz (120-300 ml) of water, juice, or your favorite beverage. Stir in a glass, or mix in a shaker cup. For best results, take HyperAmino before, during, and after training or whenever an energy fueled amino acid boost is desired. Do not exceed 3 servings in any 24 hour period.
With meals Pre During Post Between meals
Precautions
Do not exceed 3 servings in any 24 hour period.
Total caffeine from all sources is equal to 100 mg per serving.
Allergens: None known
Warning: Cancer and Reproductive harm - www.P65Warnings.ca.gov
Brand IP Statement(s)
2018 Gaspari Nutrition. Gaspari Nutrition and HyperAmino are registered trademarks of Gaspari Nutrition – All rights reserved.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HyperAmino Fruit Punch by Gaspari Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HyperAmino Fruit Punch by Gaspari Nutrition
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size10 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Hyperamino Amino Blend
- › Amino Recovery Matrix
- › Blood Flow & Performance Enhancement Matrix
- › Essential Amino Matrix
- › BCAA 2:1:1 Matrix
Hyperamino Hyper Energy Matrix
Other (inactive) ingredients: Natural and Artificial flavor, Citric Acid, Silicon Dioxide, Malic Acid, Sucralose, Acesulfame-Potassium, FD&C Red #40 Lake. These complete the product’s ingredient list but are not active constituents.
HyperAmino Fruit Punch by Gaspari Nutrition Drug Interactions
HelloPharmacist Interaction Report
HyperAmino Fruit Punch by Gaspari Nutrition contains several amino acids and plant extracts that interact with medications.
The most serious interaction involves green tea extract and the blood pressure medication nadolol (Corgard) — green tea can reduce nadolol levels by roughly 85%, which may cause blood pressure to rise uncontrollably.
Read the full breakdown — every affected drug type, severity by severity
Green tea extract also carries Major-severity interactions with ephedrine (a decongestant and stimulant) and atorvastatin (Lipitor, a cholesterol drug). Combined use with ephedrine raises the risk of serious heart, stroke, and seizure problems.
Atorvastatin levels drop about 24% when taken with green tea extract, potentially reducing its cholesterol-lowering effect.
Several other ingredients bring Moderate-severity concerns. L-phenylalanine may reduce effectiveness of levodopa (a Parkinson's medication), compete with baclofen (a muscle relaxant) for absorption, and theoretically raise blood pressure dangerously if combined with older antidepressants called MAOIs.
L-tyrosine might decrease levodopa effectiveness or add to thyroid hormone effects. Taurine could increase blood pressure drop with antihypertensive drugs or raise lithium levels.
Green tea and guarana (both caffeine-containing) may weaken several seizure medications. Altogether, these interactions span 1,381 individual medications.
We could not check L-isoleucine, L-valine, L-citrulline, L-arginine, and L-leucine — no interaction data is on file for them. Check your exact medications with the tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against HyperAmino Fruit Punch?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in HyperAmino Fruit Punch interact with 1,402 drugs. Click any drug to see the details.
2 of the 6 ingredients in HyperAmino Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Green Tea extract Guarana extract
Aminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with HyperAmino Fruit Punch — through 3 ingredients. Tap an ingredient for the detail:
Guarana ExtractStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Guarana Extract + Aminophylline, Amobarbital, Ephedrine interactionGreen Tea ExtractStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Aminophylline, Amobarbital, Ephedrine interactionL-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Aminophylline, Amobarbital, Ephedrine interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractAtorvastatin (lipitor), Hepatotoxic Drugs +2 Major
Interaction Summary
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
Read the full Green Tea Extract + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractOrganic Anion-transporting Polypeptide Substrates (oatp), Atorvastatin (lipitor) +2 Major
Interaction Summary
Theoretically, green tea might reduce the absorption of organic anion-transporting polypeptide (OATP) substrates.
Read the full Green Tea Extract + Atorvastatin Calcium interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with HyperAmino Fruit Punch — through 3 ingredients. Tap an ingredient for the detail:
Green Tea ExtractNadolol (corgard), Diuretic Drugs Major
Interaction Summary
Green tea seems to reduce the levels and clinical effects of nadolol.
Read the full Green Tea Extract + Bendroflumethiazide, Nadolol interactionMicronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Bendroflumethiazide, Nadolol interactionGuarana ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, using guarana with diuretic drugs might increase the risk of hypokalemia.
Read the full Guarana Extract + Bendroflumethiazide, Nadolol interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-phenylalanine, MicronizedLevodopa Major
Interaction Summary
Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Read the full L-phenylalanine, Micronized + Benserazide, Levodopa interactionL-tyrosineLevodopa Moderate
Interaction Summary
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Read the full L-tyrosine + Benserazide, Levodopa interactionCarbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine TannateQuadratuss, Ry Tuss, Rynatuss, Tri Tannate Plus
How Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Ephedrine +1 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionGuarana ExtractStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Guarana Extract + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-phenylalanine, MicronizedLevodopa Major
Interaction Summary
Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Read the full L-phenylalanine, Micronized + Carbidopa, Levodopa interactionL-tyrosineLevodopa Moderate
Interaction Summary
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Read the full L-tyrosine + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-phenylalanine, MicronizedLevodopa Major
Interaction Summary
Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Read the full L-phenylalanine, Micronized + Carbidopa, Levodopa, Entacapone interactionL-tyrosineLevodopa Moderate
Interaction Summary
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Read the full L-tyrosine + Carbidopa, Levodopa, Entacapone interactionDyphylline, Ephedrine, Guaifenesin, PhenobarbitalLufyllin-EPG
How Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Guarana ExtractPhenobarbital (luminal), Ephedrine +1 Major
Interaction Summary
Theoretically, guarana might reduce the effects of phenobarbital and increase the risk for convulsions.
Read the full Guarana Extract + Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interactionGreen Tea ExtractEphedrine, Stimulant Drugs +1 Major
Interaction Summary
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Read the full Green Tea Extract + Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interactionEphedrine, Guaifenesin (otc Drug)Ephedrine Formula 400, Ephedrine Plus Tabs
How Ephedrine, Guaifenesin (otc Drug) interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Guaifenesin (otc Drug) interactionGuarana ExtractEphedrine, Stimulant Drugs Major
Interaction Summary
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Read the full Guarana Extract + Ephedrine, Guaifenesin (otc Drug) interactionEphedrine, Guaifenesin, Phenobarbital, TheophyllineMudrane GG
How Ephedrine, Guaifenesin, Phenobarbital, Theophylline interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractTheophylline, Phenobarbital (luminal) +2 Major
Interaction Summary
Theoretically, green tea might increase the levels and adverse effects of theophylline.
Read the full Green Tea Extract + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionGuarana ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Guarana Extract + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionEphedrine, Hydroxyzine, TheophyllineAmi Rax, Marax
How Ephedrine, Hydroxyzine, Theophylline interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Guarana ExtractTheophylline, Ephedrine +1 Major
Interaction Summary
Theoretically, guarana might increase the levels and adverse effects of theophylline.
Read the full Guarana Extract + Ephedrine, Hydroxyzine, Theophylline interactionGreen Tea ExtractStimulant Drugs, Theophylline +1 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Hydroxyzine, Theophylline interactionEphedrine, Phenobarbital, Potassium Iodide, TheophyllineMudrane, Quadrinal
How Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Guarana ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Guarana Extract + Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interactionGreen Tea ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interactionEphedrine, Phenobarbital, TheophyllineTedral
How Ephedrine, Phenobarbital, Theophylline interacts with HyperAmino Fruit Punch — through 3 ingredients. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Phenobarbital, Theophylline interactionGuarana ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Guarana Extract + Ephedrine, Phenobarbital, Theophylline interactionL-glutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full L-glutamine + Ephedrine, Phenobarbital, Theophylline interactionEzetimibe, AtorvastatinLiptruzet
How Ezetimibe, Atorvastatin interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +2 Major
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Ezetimibe, Atorvastatin interactionLevodopaInbrija, Larodopa
How Levodopa interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-phenylalanine, MicronizedLevodopa Major
Interaction Summary
Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Read the full L-phenylalanine, Micronized + Levodopa interactionL-tyrosineLevodopa Moderate
Interaction Summary
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Read the full L-tyrosine + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-phenylalanine, MicronizedLevodopa Major
Interaction Summary
Phenylalanine, especially in high doses, can reduce the effectiveness of levodopa.
Read the full L-phenylalanine, Micronized + Levodopa, Carbidopa interactionL-tyrosineLevodopa Moderate
Interaction Summary
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Read the full L-tyrosine + Levodopa, Carbidopa interactionMemantineEbixa
How Memantine interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
L-threonine, MicronizedNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine, Micronized + Memantine interactionMemantine HydrochlorideNamenda
How Memantine Hydrochloride interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
L-threonine, MicronizedNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine, Micronized + Memantine Hydrochloride interactionMemantine, DonepezilNamzaric
How Memantine, Donepezil interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
L-threonine, MicronizedNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine, Micronized + Memantine, Donepezil interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Memantine, Donepezil interactionNadololCorgard, Nadolol
How Nadolol interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractNadolol (corgard) Major
Interaction Summary
Green tea seems to reduce the levels and clinical effects of nadolol.
Read the full Green Tea Extract + Nadolol interactionMicronized L-taurineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Micronized L-taurine + Nadolol interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abacavir, Lamivudine interactionAbametapirXeglyze
How Abametapir interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 1a2 (cyp1a2) Inhibitors Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Read the full Green Tea Extract + Abametapir interactionGuarana ExtractCytochrome P450 1a2 (cyp1a2) Inhibitors Minor
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Read the full Guarana Extract + Abametapir interactionAbciximabReoPro
How Abciximab interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Abciximab interactionGuarana ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, guarana may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Guarana Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abiraterone interactionGuarana ExtractCytochrome P450 1a2 (cyp1a2) Inhibitors Minor
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Read the full Guarana Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with HyperAmino Fruit Punch — through 2 ingredients. Tap an ingredient for the detail:
Guarana ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, guarana may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Guarana Extract + Abrocitinib interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with HyperAmino Fruit Punch — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acalabrutinib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in HyperAmino Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Green Tea extract
Atorvastatin (Lipitor)
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
In healthy humans, taking green tea extract 300 mg or 600 mg along with atorvastatin reduces plasma levels of atorvastatin by approximately 24%. The elimination of atorvastatin is not affected. Atorvastatin is a substrate of organic anion-transporting polypeptides (OATPs). Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs. Some OATPs are expressed in the small intestine and are responsible for the uptake of drugs and other compounds, which may have resulted in reduced plasma levels of atorvastatin. It is not clear if drinking green tea alters the absorption of atorvastatin.
Ephedrine
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Green tea contains caffeine. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.
Nadolol (Corgard)
Green tea seems to reduce the levels and clinical effects of nadolol.
Preliminary clinical research shows that green tea consumption reduces plasma concentrations of nadolol. Compared to a control group, both peak levels and total drug exposure (AUC) of nadolol were reduced by approximately 85% in subjects who drank green tea daily for two weeks. Drinking green tea with nadolol also significantly reduced nadolol's systolic blood pressure lowering effect. Other clinical research shows that a single dose of green tea can affect plasma nadolol levels for at least one hour. Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is involved in the uptake of nadolol in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
5-Fluorouracil
Theoretically, high doses of green tea might increase the effects and side effects of 5-fluorouracil.
Animal research shows that taking green tea in amounts equivalent to about 6 cups daily in humans for 4 weeks prior to receiving a single injection of 5-fluorouracil increases the maximum plasma levels of 5-fluorouracil by about 2.5-fold and the area under the curve by 425%.
Adenosine (Adenocard)
Theoretically, green tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine doesn't seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Anticoagulant/Antiplatelet Drugs
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Conflicting reports exist regarding the effect of green tea on bleeding risk when used with anticoagulant or antiplatelet drugs; however, most evidence suggests that drinking green tea in moderate amounts is unlikely to cause a significant interaction. Green tea contains small amounts of vitamin K, approximately 7 mcg per cup. Some case reports have associated the antagonism of warfarin with the vitamin K content of green tea. However, these reports are rare, and very large doses of green tea (about 8-16 cups daily) appear to be needed to cause these effects. Furthermore, the catechins and caffeine in green tea are reported to have antiplatelet activity.
Beta-Adrenergic Agonists
Green tea contains caffeine. Theoretically, concomitant use of large amounts of caffeine might increase cardiac inotropic effects of beta-agonists.
Bortezomib (Velcade)
Theoretically, green tea might interfere with the effects of bortezomib.
In vitro research shows that green tea polyphenols, such as epigallocatechin gallate (EGCG), interact with bortezomib and block its proteasome inhibitory action. This prevents the induction of cell death in multiple myeloma or glioblastoma cancer cell lines. Advise patients taking bortezomib, not to take green tea.
Carbamazepine (Tegretol)
Theoretically, green tea might reduce the effects of carbamazepine and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.
Celiprolol (Celicard)
Theoretically, green tea might reduce the levels and clinical effects of celiprolol.
In a small human study, taking green tea daily for 4 days appears to decrease blood and urine levels of celiprolol by at least 98%. This interaction is possibly due to the inhibition of organic anion transporting polypeptide (OATP). Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is found in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
Cimetidine (Tagamet)
Theoretically, concomitant use might increase the effects and adverse effects of caffeine in green tea.
Green tea contains caffeine. Cimetidine can reduce caffeine clearance by 31% to 42%.
Clozapine (Clozaril)
Theoretically, green tea might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Animal research suggests that, although green tea extract does not affect the elimination of clozapine, it delays the time to reach peak concentration and reduces the peak plasma levels. Also, concomitant administration of green tea and clozapine might theoretically cause acute exacerbation of psychotic symptoms due to the caffeine in green tea. Caffeine can increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg daily inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Researchers speculate that caffeine might inhibit CYP1A2. However, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients be more sensitive to the interaction between clozapine and caffeine.
Contraceptive Drugs
Theoretically, concomitant use might increase the effects and adverse effects of caffeine found in green tea.
Green tea contains caffeine. Oral contraceptives can decrease caffeine clearance by 40% to 65%.
Cytochrome P450 1A2 (Cyp1A2) Inhibitors
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Caffeine is metabolized by cytochrome P450 1A2 (CYP1A2),. Theoretically, drugs that inhibit CYP1A2 may decrease the clearance rate of caffeine from green tea and increase caffeine levels.
Dipyridamole (Persantine)
Theoretically, green tea might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine might inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Disulfiram (Antabuse)
Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
In human research, disulfiram decreases the clearance and increases the half-life of caffeine.
Diuretic Drugs
Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.
Green tea contains caffeine. In excessive amounts, caffeine can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.
Estrogens
Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Estrogen inhibits caffeine metabolism.
Ethosuximide (Zarontin)
Theoretically, green tea might reduce the effects of ethosuximide and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.
Felbamate (Felbatol)
Theoretically, green tea might reduce the effects of felbamate and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.
Fexofenadine (Allegra)
Green tea can decrease blood levels of fexofenadine.
Clinical research shows that green tea can significantly decrease blood levels and excretion of fexofenadine. Taking green tea extract with a dose of fexofenadine decreased bioavailability of fexofenadine by about 30%. In vitro, green tea inhibits the cellular accumulation of fexofenadine by inhibiting the organic anion transporting polypeptide (OATP) drug transporter. Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs, specifically OATP1A2, OATP1B1, and OATP2B1. In addition, green tea has been shown to reduce the absorption of some drugs that are OATP substrates.
Flutamide (Eulexin)
Theoretically, green tea might increase the levels and adverse effects of flutamide.
Green tea contains caffeine. In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. Theoretically, concomitant use of caffeine and flutamide might increase serum concentrations of flutamide and increase the risk adverse effects.
Fluvoxamine (Luvox)
Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Fluvoxamine reduces caffeine metabolism.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Green tea extract supplements have been linked to several cases of hepatotoxicity and might have additive hepatotoxic effects with other drugs..
Imatinib (Gleevec)
Theoretically, green tea might reduce the levels and clinical effects of imatinib.
In animal research, a single dose of green tea extract reduces the area under the curve (AUC) of imatinib by up to approximately 64% and its main metabolite N-desmethyl imatinib by up to approximately 81%. This interaction has not been shown in humans. The mechanism of action is unclear but may involve multiple pathways.
Guarana extract
Ephedrine
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Guarana contains caffeine. Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.
Adenosine (Adenocard)
Theoretically, guarana might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Guarana contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Anticoagulant/Antiplatelet Drugs
Theoretically, guarana may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that guarana extract can inhibit platelet aggregation. This effect may be due to the caffeine in guarana, which is also reported to have antiplatelet activity. This interaction has not been reported in humans.
Beta-Adrenergic Agonists
Theoretically, concomitant use might increase the clinical effects of beta-adrenergic agonists.
Guarana contains caffeine. Theoretically, concomitant use of large amounts of caffeine might increase cardiac inotropic effects of beta-agonists.
Carbamazepine (Tegretol)
Theoretically, guarana might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when given to animals in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine two-fold in healthy individuals.
Cimetidine (Tagamet)
Theoretically, concomitant use might increase the effects and adverse effects of caffeine in guarana.
Guarana contains caffeine. Cimetidine decreases the rate of caffeine clearance by 31% to 42%.
Clozapine (Clozaril)
Theoretically, guarana might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Guarana contains caffeine. Caffeine can increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Researchers speculate that caffeine might inhibit CYP1A2. However, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to the interaction between clozapine and caffeine.
Dipyridamole (Persantine)
Theoretically, guarana might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Guarana contains caffeine. Caffeine might inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole than adenosine-induced stress testing.
Disulfiram (Antabuse)
Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
In human research, disulfiram decreases the clearance and increases the half-life of caffeine.
Diuretic Drugs
Theoretically, using guarana with diuretic drugs might increase the risk of hypokalemia.
Guarana contains caffeine. Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also lower potassium levels.
Estrogens
Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Guarana contains caffeine. Estrogen inhibits caffeine metabolism.
Ethosuximide (Zarontin)
Theoretically, guarana might reduce the effects of ethosuximide and increase the risk for convulsions.
Guarana contains caffeine. Animal research shows that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. This effect has not been observed in humans.
Felbamate (Felbatol)
Theoretically, guarana might reduce the effects of felbamate and increase the risk for convulsions.
Guarana contains caffeine. Animal research shows that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. This effect has not been observed in humans.
Flutamide (Eulexin)
Theoretically, guarana might increase the levels and adverse effects of flutamide.
Guarana contains caffeine. In vitro evidence shows that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.
Fluvoxamine (Luvox)
Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Guarana contains caffeine. Fluvoxamine reduces caffeine metabolism.
Lithium
Theoretically, abrupt guarana withdrawal might increase the levels and adverse effects of lithium.
Guarana contains caffeine. Theoretically, abrupt caffeine withdrawal might increase serum lithium levels. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Guarana contains caffeine. Caffeine has been shown to inhibit MAO-A and -B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.
Nicotine
Theoretically, concomitant use might increase the risk of hypertension.
Guarana contains caffeine. Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.
Pentobarbital (Nembutal)
Theoretically, guarana might decrease the effects of pentobarbital.
Guarana contains caffeine. In vivo evidence suggests that caffeine can negate the hypnotic effects of pentobarbital in humans. However, animal research suggests that guarana does not alter the hypnotic effect of pentobarbital.
Phenobarbital (Luminal)
Theoretically, guarana might reduce the effects of phenobarbital and increase the risk for convulsions.
Guarana contains caffeine. Animal research shows that caffeine can decrease the anticonvulsant activity of phenobarbital. The exact mechanism of this interaction is unclear.
Phenylpropanolamine
Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Guarana contains caffeine. Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.
Phenytoin (Dilantin)
Theoretically, guarana might reduce the effects of phenytoin and increase the risk for convulsions.
Guarana contains caffeine. Animal research shows that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.
Pioglitazone (Actos)
Theoretically, guarana might increase the levels and clinical effects of pioglitazone.
Guarana contains caffeine. Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.
Riluzole (Rilutek)
Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Guarana contains caffeine. Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.
Stimulant Drugs
Theoretically, concomitant use might increase stimulant adverse effects.
Guarana contains caffeine. Due to the central nervous system (CNS) stimulant effects of caffeine, concomitant use with stimulant drugs can increase the risk of adverse effects.
Brand information
Manufacturer and brand details for HyperAmino Fruit Punch, from the product label.
Gaspari Nutrition
See all Gaspari Nutrition products- Name
- Gaspari Nutrition
- Street Address
- 575 Prospect St., Suite 301
- City
- Lakewood
- State
- NJ
- ZipCode
- 08701
- Phone Number
- 1.732.364.3777
- Web Address
- gasparinutrition.com
HyperAmino Fruit Punch by Gaspari Nutrition: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind HyperAmino Fruit Punch’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Green Tea
Interacts with 1,293 drugsGreen tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentrated green tea extracts are a different s...
Read the full Green Tea monograph → Herb & supplement monographGuarana
Interacts with 655 drugsGuarana is an Amazonian seed that is naturally high in caffeine, which explains most of its stimulant and energy effects. While it may give a short-term boost in alertness and reduce fatigue...
Read the full Guarana monograph →Sources & How We Checked
HyperAmino Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 418 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glutamine 11 references
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- Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
- Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
- Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
- Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
- Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
- Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
- Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
- Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
- Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed
Tyrosine 4 references
- Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
- DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
- Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
- van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed
Threonine 4 references
- Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
- Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
- Blin O, Pouget J, Aubrespy G, et al. A double-blind placebo controlled trial of L-threonine in amyotrophic lateral sclerosis. J Neurol 1992;239:79-81.
- Roufs JB. L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Med Hypotheses 1991;34:20-3. PubMed
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Phenylalanine 23 references
- Rouse B, Azen C, Koch R, et al. Maternal phenylketonuria collaborative Study (MPKUCS) offspring: facial anomalies, malformations, and early neurological sequelae. Am J Med Genet 1997;69:89-95. DOI
- Sturtevant FM. Use of aspartame in pregnancy. Int J Fertil 1985;30:85-7.
- Silkaitis RP, Mosnaim AD. Pathways linking L-phenylalanine and 2-phenylethylamine with p-tyramine in rabbit brain. Brain Res 1976;114:105-15.
- Lehmann WD, Theobald N, Fischer R, Heinrich HC. Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic mixture of L- and D-phenylalanine. Clin Chim Acta 1983;128 PubMed
- Mosnik DM, Spring B, Rogers K, Baruah S. Tardive dyskinesia exacerbated after ingestion of phenylalanine by schizophrenic patients. Neuropsychopharmacology 1997;16:136-46. PubMed
- Siddiqui AH, Stolk LM, Bhaggoe R, et al. L-phenylalanine and UVA irradiation in the treatment of vitiligo. Dermatology 1994;88:215-8. PubMed
- Birkmayer W, Riederer P, Linauer W, Knoll J. L-deprenyl plus L-phenylalanine in the treatment of depression. J Neural Transm 1984;59:81-7. PubMed
- Nutt JG, Woodward WR, Hammerstad JP, et al. The "on-off" phenomenon in Parkinson's disease. Relation to levodopa absorption and transport. N Engl J Med 1984;310:483-8. PubMed
- Baruzzi A, Contin M, Riva R, et al. Influence of meal ingestion time on pharmacokinetics of orally administered levodopa in parkinsonian patients. Clin Neuropharmacol 1987;10:527-37. PubMed
- Juncos JL, Fabbrini G, Mouradian MM, et al. Dietary influences on the antiparkinsonian response to levodopa. Arch Neurol 1987;44:1003-5. PubMed
- Eriksson T, Granerus AK, Linde A, et al. "On-off" phenomenon in Parkinson's disease: relationship between dopa and other large neutral amino acids in plasma. Neurology 1988;38:1245-8. PubMed
- Baker GB, Bornstein RA, Rouget AC, et al. Phenylethylaminergic mechanisms in attention-deficit disorder. Biol Psychiatry 1991;29:15-22.. PubMed
- Wood DR, Reimherr FW, Wender PH. Treatment of attention deficit disorder with DL-phenylalanine. Psychiatry Res 1985;16:21-6.. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Washington, DC: National Academy Press, 2002. Available at: http://www.n
- Cederbaum S. Phenylketonuria: an update. Curr Opin Pediatr 2002;14:702-6. PubMed
- Cejudo-Ferragud, E., Nacher, A., Polache, A., Cercos-Fortea, T., Merino, M., and Casabo, V. G. Evidence of competitive inhibition for the intestinal absorption of baclofen by phenylalanine. Int J of Pharm (Amsterdam) 1996;132:63-69. DOI
- Fischer, E., Heller, B., Nachon, M., and Spatz, H. Therapy of depression by phenylalanine. Preliminary note. Arzneimittelforschung. 1975;25(1):132.
- Beckmann, H., Strauss, M. A., and Ludolph, E. Dl-phenylalanine in depressed patients: an open study. J.Neural Transm. 1977;41(2-3):123-134. PubMed
- Sabelli, H. C., Fawcett, J., Gusovsky, F., Javaid, J. I., Wynn, P., Edwards, J., Jeffriess, H., and Kravitz, H. Clinical studies on the phenylethylamine hypothesis of affective disorder: urine and blood phenylacetic acid and phenylalanine dietary supplem
- Cotzias, G. C., Van Woert, M. H., and Schiffer, L. M. Aromatic amino acids and modification of parkinsonism. N Engl.J Med 2-16-1967;276(7):374-379. PubMed
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