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Dietary supplement

Inosine Ingredients & Drug Interactions

by Swanson

Inosine label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Inosine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Inosine is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for athletic performance and energy, multiple sclerosis (raising uric acid), parkinson's disease (raising uric acid).Based on those ingredients, 9 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Inosine by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Inosine by Swanson — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Inosine by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inosine, a compound your body makes naturally and that's found in some foods. The capsule itself is made from hypromellose (a plant-based film), with microcrystalline cellulose and magnesium stearate as inactive ingredients that help hold the capsule together and keep it stable.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Inosine product and its label doesn't state a use — see Inosine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for inosine isn't established in the data we hold. We have insufficient reliable evidence to rate it for athletic performance, amyotrophic lateral sclerosis (ALS), cancer, diabetic neuropathy (nerve damage from diabetes), or multiple sclerosis.

If you're considering it for any of these reasons, talk it over with your doctor about what the current research shows and whether it's a reasonable choice for you.

The evidence, ingredient by ingredient Inosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inosine is generally well tolerated by mouth, but it raises uric acid levels — which is the key concern. People with gout or kidney problems should be cautious, since high uric acid can trigger gout flares and kidney stones, especially if you're also taking calcium supplements.

The safety data advises against using inosine during pregnancy and while breastfeeding due to insufficient information.

Side effects, ingredient by ingredient Inosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inosine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 9 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take an antigout medication like allopurinol or febuxostat, check with your doctor or pharmacist before starting inosine. This supplement can raise uric acid and may reduce how well your gout medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Inosine may be worth considering if you're exploring options for athletic performance or certain neurological conditions, but the evidence is limited. If you have gout, kidney disease, or you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting it.

Anyone taking an antigout medication should check with their doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inosine, straight from the product label.

Brand Swanson
Barcode (UPC) 087614113791
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 308629
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inosine by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
087614113791
IngredientAmount% DV
Inosine500 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Total wellness for mind, body & home Unsurpassed purity & potency 100% money back guaranteed

Energy support

Vegetarian

Brand IP Statement(s)

Swanson Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule two times per day with water.

Seals/Symbols

Vegetarian

Precautions

Warning: For adults only. Keep out of reach of children.

Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking prescription medication or have a medical condition, especially kidney disease or gout.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Inosine by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Inosine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Inosine by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Inosine

Interacts with
9 drugs
500 mg per serving

Inosine is a nucleoside (a building block of DNA and RNA) that the body makes on its own and is also sold as a supplement, mostly marketed for athleti...

Inosine monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inosine by Swanson Drug Interactions

Want to check YOUR meds against Inosine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
9Drugs
9 Moderate

Ingredients driving the most interactions

Inosine 9

Individual Drug Interactions

The ingredients in Inosine interact with 9 drugs. Click any drug to see the details.

1 of the 1 ingredient in Inosine interact with drugs. Each result below shows which ingredient is responsible. Inosine

Each ingredient & the kinds of drugs it affects

For each ingredient in Inosine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inosine1 drug type · 9 drugs

Antigout Drugs

Inosine might reduce the effects of antigout medications.
Inosine increases uric acid levels in the serum and urine, potentially resulting in hyperuricemia and reducing the effects of medications used for the prevention and treatment of gout.

Likelihood Possible Evidence D
Inosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Inosine, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Inosine by Swanson: Common Questions

Does Inosine by Swanson interact with any medications?
Yes. Based on its ingredients, Inosine has a known interaction with 9 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inosine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will inosine hurt my kidneys?
Inosine raises uric acid, which can form crystals and kidney stones — especially at higher doses (1–2 grams daily) or if you're also taking calcium supplements. If you have a history of kidney problems, talk with your doctor before taking it.
Can I take inosine if I have gout?
No — inosine raises uric acid levels, which can trigger gout flares and may weaken any gout medication you're on. Skip this one and check with your doctor about safer options.
Is inosine safe in pregnancy or while breastfeeding?
The safety data advises against it. There isn't enough information to know it's safe during pregnancy or breastfeeding, so it's best to avoid it during these times. Talk with your doctor or pharmacist if you have questions.
What are the most common side effects?
High uric acid levels, kidney stones, and uric acid crystals in the urine are the main concerns. Most people tolerate it orally without major problems, but these risks increase especially at higher doses.
Does inosine actually work for athletic performance?
The evidence we have isn't strong enough to say. There's insufficient reliable evidence to rate it for athletic performance, so it's unclear whether it'll help you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inosine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inosine label
Go deeper

The Full Monographs Behind Inosine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inosine

Interacts with 9 drugs

Inosine is a nucleoside (a building block of DNA and RNA) that the body makes on its own and is also sold as a supplement, mostly marketed for athletic performance. Solid evidence that it bo...

Read the full Inosine monograph →
Sources

Sources & How We Checked

Inosine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inosine 7 references
  1. Parkinson Study Group SURE-PD Investigators. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014;71(2):141-50.
  2. Muñoz García D, Midaglia L, Martinez Vilela J, et al. Associated inosine to interferon: results of a clinical trial in multiple sclerosis. Acta Neurol Scand. 2015;131(6):405-10. PubMed
  3. Gonsette RE, Sindic C, D'hooghe MB, et al. Boosting endogenous neuroprotection in multiple sclerosis: The association of inosine and interferon beta in relapsing-remitting Multiple Sclerosis (ASIIMS) trial. Mult Scler. 2010;16(4):455-62.
  4. Markowitz CE, Spitsin S, Zimmerman V, et al. The treatment of multiple sclerosis with inosine. J Altern Complement Med. 2009;15(6):619-25. PubMed
  5. Watanabe H, Hattori T, Kume A, et al. Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine. Medicine (Baltimore) 2020;99(35):e21576. PubMed
  6. Parkinson Study Group SURE-PD3 Investigators, Schwarzschild MA, Ascherio A, et al. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA 2021;326(10):926-939.
  7. Walk D, Nicholson K, Locatelli E, et al. Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle Nerve 2023;67(5):378-386. PubMed

See these in context on the Inosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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