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Dietary supplement

Ionic Elements Ingredients & Drug Interactions

by Purium

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Ionic Elements is a dietary supplement by Purium with 3 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are supercharged activated Fulvic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ionic Elements by Purium

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “All Natural Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.50 mL) without saying how much of each component you get.

Ionic Elements is a liquid supplement with 3 active ingredients: purified water, trace minerals, and a proprietary blend that includes supercharged activated fulvic acid. Fulvic acid is a compound derived from organic matter that's included here for its potential roles in immune support and mineral absorption, though the evidence for its clinical benefits remains limited.

The product contains no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Mineral and nutrient supplementation.
  • We looked for evidence on: General wellness, Energy support, Nutrient absorption.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for fulvic acid isn't established in our data. We hold insufficient reliable evidence to rate it for respiratory tract infections, lead toxicity, eczema, fatigue, or hay fever.

That doesn't mean it doesn't work — it means high-quality human studies are lacking. If you're considering this product for a specific health concern, talk with your pharmacist or doctor about what the research actually shows.

The evidence, ingredient by ingredient Fulvic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of fulvic acid appears generally well tolerated. The most common side effects reported in trials are diarrhea, headache, and sore throat.

High-quality human safety data is limited, so we don't have a complete picture of longer-term use. The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.

Side effects, ingredient by ingredient Fulvic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 257 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Ionic Elements, make sure to check your blood thinners or antiplatelet drugs (like warfarin or clopidogrel), immunosuppressants, and thyroid hormone therapy — fulvic acid may reduce how well these work. Use the medication checker below to verify your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Ionic Elements is best considered by people interested in trace mineral supplementation who don't take blood thinners, immunosuppressants, or thyroid medications. If you're on any of those drugs, or if you're pregnant, breastfeeding, or have questions about whether this fits your health picture, check with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ionic Elements, straight from the product label.

Brand Purium
Barcode (UPC) 764934021202
Net contents 4 Fluid Ounce(s); 120 Milliliter(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 332338
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ionic Elements by Purium, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.5 mL
Maximum serving Sizes:
1.5 mL
Servings per container
80
UPC/BARCODE
764934021202
IngredientAmount% DV
Water, Purified0 NP--
Trace Minerals0 NP--
All Natural Proprietary Blend1.5 mL--
supercharged activated Fulvic Acid0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Pure + Premium = Purium Co-founders Amy Venner and Dave Sandoval are passionate about making the world a better place. With over 60 years combined experience, they provide the highest quality superfood nutrition while practicing commerce with a conscience and serving their community. Their dedication safeguards Purium's commitment to provide pure and premium superfoods; grown, manufactured and tested to the highest standards. From farm to family, Purium delivers the finest nutrition with the lowest possible environmental impact.

The transformation company The quality of food you eat is equal to the quality of life you live. Learn more about Purium

Suggested/Recommended/Usage/Directions

Suggested use: Mix approximately 20 drops (2 droppers fully) with 8-10 oz of water or any other beverage. May be taken 3 times per day. Do not drink undiluted. Shake well before use.

Precautions

Do not drink undiluted.

Caution: Keep out of reach of children.

If you have a medical condition, are pregnant, lactating or taking medication, consult your health care professional before using this or any other nutritional supplement.

Storage

Store in a cool, dry place. Cover tightly.

Formula

Magnesium rich trace minerals & fulvic acid

Formulation

Vegan & Gluten-free

Vegan & Gluten-free

FDA Statement of Identity

Dietary Supplement

See for yourself

Ionic Elements by Purium label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ionic Elements by Purium

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.5 mL Dosage formLiquid Servings per container80 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

All Natural Proprietary Blend

1.5 mL per serving
Interaction report

Ionic Elements by Purium Drug Interactions

Want to check YOUR meds against Ionic Elements?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
257Drugs
257 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Ionic Elements with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

supercharged activated Fulvic Acid3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Ionic Elements, from the product label.

Purium

See all Purium products
Name
Purium
Street Address
2610 Homestead Pl.
City
Rancho Dominiguez
State
CA
ZipCode
90220
Phone Number
1.888.747.6733
Web Address
ishoppurium.com
Pharmacist Counseling Corner

Ionic Elements by Purium: Common Questions

Does Ionic Elements by Purium interact with any medications?
Yes. Based on its ingredients, Ionic Elements has a known interaction with 257 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ionic Elements contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know whether it's safe during pregnancy or while breastfeeding, so talk with your doctor or pharmacist about what's right for your situation.
What side effects should I watch for?
The most common ones reported are diarrhea, headache, and sore throat. These happened in some people in trials, but serious side effects are rare. Stop and call your doctor if anything unusual develops.
Is fulvic acid proven to work for anything?
We don't have enough reliable evidence in our data to say it works for respiratory infections, lead toxicity, eczema, fatigue, or hay fever. If you're taking it for a specific reason, ask your pharmacist what the current research supports.
What is fulvic acid supposed to do?
It's included in this product for its potential roles in immune support and helping your body absorb minerals, but the human evidence is limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ionic Elements is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ionic Elements label
Sources

Sources & How We Checked

Ionic Elements's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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