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Dietary supplement

Jiaogulan Extract Ingredients & Drug Interactions

by Paradise

Jiaogulan Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Jiaogulan Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Jiaogulan Extract is a dietary supplement by Paradise with 1 active ingredient. Its ingredients are commonly taken for fatigue and stress (adaptogen), blood sugar support, high blood pressure.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Jiaogulan extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Jiaogulan Extract by Paradise

Ask about any prescription or over-the-counter medication and we check it for interactions with Jiaogulan Extract by Paradise — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Jiaogulan Extract by Paradise

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic jiaogulan extract. Jiaogulan is a plant traditionally used in herbal medicine.

The capsule also contains cellulose, an inactive ingredient used as a filler.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Jiaogulan's overall clinical evidence instead.

Moderate

Some clinical evidence supports Jiaogulan for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

The evidence for jiaogulan is mixed and depends on what you're taking it for. For blood sugar control in diabetes, the data suggests it may be effective—clinical research shows jiaogulan can lower blood glucose levels.

For other uses listed here—athletic performance, cancer, heart disease, liver health, and respiratory infections—we don't yet have enough reliable evidence to say whether it works.

The evidence, ingredient by ingredient Jiaogulan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Jiaogulan is generally well tolerated when used short-term (up to 4 months in studies), but long-term safety hasn't been well studied. The most common side effects are diarrhea and nausea.

Some people also report dry mouth, dizziness, or trouble sleeping. Avoid this product if you're pregnant or breastfeeding.

Safety data during pregnancy and lactation hasn't been established, and it may affect a developing baby. Talk with your pharmacist or doctor for personalized advice if you're in either situation.

Side effects, ingredient by ingredient Jiaogulan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Jiaogulan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take blood thinners or antiplatelet drugs (moderate risk of increased bleeding), immunosuppressants (moderate risk of reduced effectiveness), or diabetes medications (moderate risk of low blood sugar). These are the main medication types you should verify against your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Jiaogulan may help with blood sugar management if you have diabetes, but it comes with real interaction risks—especially with blood thinners, immune suppressants, and diabetes medications. If you take any of those, check with your pharmacist first.

Otherwise, it's generally well tolerated for short-term use, though long-term safety remains unclear.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jiaogulan Extract, straight from the product label.

Brand Paradise
Barcode (UPC) 601944777449
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336866
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jiaogulan Extract by Paradise, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
601944777449
IngredientAmount% DV
organic Jiaogulan extract250 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Quality purity potency We are dedicated to sourcing premium ultra pure ingredients that meet the highest standards of excellence.

We never add unnecessary fillers, binders, preservatives or glow agents to our encapsulation process. Our active whole spectrum extracts contain a full profile of naturally occurring constituents and are extracted without the use of toxic solvents and/or harsh chemicals.

Vegan

Non-GMO Gluten free

Vital energy adaptogen anti-stress + wellness herb

Contains no common allergens. Made without fillers.

Raw Material: Jiaogulan extract 12:1 naturally containing a full spectrum of active synergistic constituents including important gypenosides.

Manufactured in the USA. GMP Quality Assured & FDA Registered.

General Statements

Paradise products have won over a decade of Best of Supplements Awards.

Formula

Active whole spectrum difference Our active whole spectrum extracts contain a full profile of naturally occurring constituents and are extracted without the use of toxic solvents and/or harsh chemicals. This unique method captures the true essence of the whole herb while still retaining a highly active and bioavailable concentration of phyto nutrients.

Storage

Warning: Keep in a cool dry place, out of the reach of children.

Precautions

Warning: Keep in a cool dry place, out of the reach of children.

If pregnant, nursing, or using any prescription medication consult your health care professional before using this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Paradise Enhancing Nature's Miracles Since 1994 Paradise EST. 1994

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 vegetarian capsule 1-2 times daily or as directed by a qualified health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Jiaogulan Extract by Paradise label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Jiaogulan Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Jiaogulan Extract by Paradise

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Organic Jiaogulan extract

Interacts with
327 drugs
250 mg per serving

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and...

Organic Jiaogulan extract monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Jiaogulan Extract by Paradise Drug Interactions

Want to check YOUR meds against Jiaogulan Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

organic Jiaogulan extract 327

Individual Drug Interactions

The ingredients in Jiaogulan Extract interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Jiaogulan Extract interact with drugs. Each result below shows which ingredient is responsible. organic Jiaogulan extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Jiaogulan Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Jiaogulan extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that jiaogulan has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, jiaogulan might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that jiaogulan can lower blood glucose levels.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Clinical and animal studies suggest that jiaogulan can stimulate the immune system.

Likelihood Possible Evidence D
organic Jiaogulan extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Jiaogulan Extract, from the product label.

Paradise

See all Paradise products
Name
Paradise Herbs & Essentials, Inc.
Street Address
19051 Goldenwest St. #106-304
City
Huntington Beach
State
CA
ZipCode
92648
Web Address
www.paradiseherbs.com
Pharmacist Counseling Corner

Jiaogulan Extract by Paradise: Common Questions

Does Jiaogulan Extract by Paradise interact with any medications?
Yes. Based on its ingredients, Jiaogulan Extract has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jiaogulan Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
You'll need to check with your pharmacist first. Jiaogulan may increase bleeding risk when combined with blood thinners and antiplatelet drugs, so your exact medication and dose matter. Don't start this without running it by them.
Does jiaogulan actually work for diabetes?
Clinical research shows jiaogulan can lower blood glucose levels, so it's rated possibly effective for diabetes. That said, if you're already on diabetes medication, the combination might lower your blood sugar too much, so again—check with your pharmacist first.
What are the side effects?
Most common are diarrhea and nausea. Dry mouth, dizziness, and insomnia have also been reported. Studies have looked at use up to 4 months, but we don't know much about what happens with longer use.
Is it safe to take while pregnant or breastfeeding?
No. Safety hasn't been established during pregnancy or while breastfeeding, and jiaogulan may affect a developing baby. Talk with your doctor or pharmacist if you're pregnant or nursing.
Does this contain any fillers?
Yes, the capsule also contains cellulose, which is an inactive ingredient used as a filler.
How long can I take this safely?
Studies have looked at use up to 4 months and found it generally well tolerated. Long-term safety beyond that isn't well studied, so it's worth discussing longer use with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Jiaogulan Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jiaogulan Extract label
Go deeper

The Full Monographs Behind Jiaogulan Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Jiaogulan

Interacts with 327 drugs

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and animal studies are promising for some u...

Read the full Jiaogulan monograph →
Sources

Sources & How We Checked

Jiaogulan Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Jiaogulan 8 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhingguo Zhong Xi Yi Jie He Za Zhi 1993;13:278-80.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. J Nutr Metab. 2013;2013:765383. doi: 10.1155/2013/765383.
  5. Li Y, Lin W, Huang J, Xie Y, Ma W. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan). Chin Med. 2016 Sep 27;11:43. Review. PubMed
  6. Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CG. Antidiabetic effect of add-on Gynostemma pentaphyllum extract therapy with sulfonylureas in type 2 diabetic patients. Evid Based Complement Alternat Med 2012; 452313.
  7. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab Res. 2010;42(5):353-7.
  8. Rao A, Clayton P, Briskey D. The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double-blind, randomised, placebo-controlled study. J Hum Nutr Diet 2021.

See these in context on the Jiaogulan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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