Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Kickstart RX Ingredients & Drug Interactions

by AMMO American Muscle Mass Optimization

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Kickstart RX is a dietary supplement by AMMO American Muscle Mass Optimization with 3 active ingredients. Its ingredients are commonly taken for lowering estrogen levels, post-cycle therapy after steroid or prohormone use, reducing gynecomastia ('gyno').Based on those ingredients, 4 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androst-3, 5-dien-7, 17-dione. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Kickstart RX by AMMO American Muscle Mass Optimization

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Kickstart RX contains 3 active ingredients: Androst-3, 5-dien-7, 17-dione (also called Arimistane), Fadogia Agrestis P.E., and 4-Hydroxyandrostenedione. The product has no inactive ingredients listed.

Arimistane is marketed as an estrogen-modulating compound; Fadogia Agrestis is a plant extract traditionally used in some cultures; and 4-Hydroxyandrostenedione is a related androgenic compound.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Post cycle therapy testosterone and estrogen support.
  • We looked for evidence on: Athletic performance, Muscle strength, Erectile dysfunction (ED), Sexual arousal, Hormonal balance, Gynecomastia — and 2 related terms.
  • The closest evidence on file: Fadogia Agrestis is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Fadogia Agrestis is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).
  • Also on file: Arimistane is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Erectile dysfunction (ED), Muscle strength, Sexual arousal.

The evidence supporting these ingredients is limited. For Arimistane, we hold insufficient reliable evidence to rate its effectiveness for athletic performance, muscle strength, erectile dysfunction, sexual arousal, or obesity.

Fadogia Agrestis likewise lacks sufficient evidence for athletic performance, erectile dysfunction, or malaria. The effectiveness claims made in marketing for this product are not backed by data we can point to.

The evidence, ingredient by ingredient Arimistane Fadogia Agrestis

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This product carries real safety concerns. Arimistane is a hormone-altering drug with very little safety data, and regulators specifically warn against aromatase inhibitor supplements — do not use it if you are pregnant or breastfeeding.

Fadogia Agrestis also lacks human safety data, and animal studies hint at possible toxicity to the testicles, liver, and kidneys; it too should be avoided during pregnancy and breastfeeding. No adverse effects from trial use are reported in our data, but the lack of human studies means risks aren't fully known.

Side effects, ingredient by ingredient Arimistane Fadogia Agrestis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Arimistane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 4 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Kickstart RX, check with your doctor or pharmacist if you're on any aromatase inhibitors (anastrozole, letrozole, exemestane, or related drugs used for hormone-sensitive cancers and conditions). This is the only medication type with documented interactions, rated as Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're taking an aromatase inhibitor medication, this product is not for you without a doctor's clearance. Even if you're not, the hormone-altering nature of Arimistane and the toxicity signals from animal studies of Fadogia Agrestis mean this is not a supplement to take lightly.

Talk it over with your doctor or pharmacist before starting — they can weigh whether the unproven benefits match the documented safety gaps for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kickstart RX, straight from the product label.

Brand AMMO American Muscle Mass Optimization
Barcode (UPC) 805105576401
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2012
DSLD ID 11334
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kickstart RX by AMMO American Muscle Mass Optimization, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
805105576401
IngredientAmount% DV
Androst-3, 5-dien-7, 17-dione50 mg--
Fadogia Agrestis P.E.1500 mg--
4-Hydroxyandrostenedione100 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Consult a physician or licensed qualified health care professional before using this product. If you have, or have a family history of prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug or over the counter drug. Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include but are not limited to: acne, hair loss, hair growth on the face (in women), aggressiveness, irritability. Discontinue using this product and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision or other similar symptoms. This product may elevate serum hormone levels which could produce a positive result if you are subject to NCAA testing.

Warning: Not for women or for individuals under the age of 18.

General Statements

ARM YOURSELF Kick start RX, the most comprehensive post cycle product to hit the market! What makes Kick Start RX so superior to other PCT's on the market? It's the combination of Formestane, which is the most studied Aromatase inhibitor in history, and the new Cortisol and Estrogen inhibiting compound Adrost-3, 5-dien-7, 17-dione. If you are serious about keeping your gains, you need Kick Start RX for your Post Cycle Therapy needs!

Post Cycle Therapy

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Consume 1 capsule 3 times daily. Do not exceed 3 capsules in a 24 hour period. Do not exceed 8 continuous weeks of use followed by a 4 week break.

See for yourself

Kickstart RX by AMMO American Muscle Mass Optimization label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Kickstart RX by AMMO American Muscle Mass Optimization

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Androst-3, 5-dien-7, 17-dione

Interacts with
4 drugs
50 mg per serving

Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone,...

Androst-3, 5-dien-7, 17-dione monograph & interactions

Fadogia Agrestis P.E.

No known
interactions
1500 mg per serving

Fadogia agrestis is a West African shrub marketed as a testosterone booster, but human evidence is essentially nonexistent and what we know comes most...

Fadogia Agrestis P.E. monograph & interactions

4-Hydroxyandrostenedione

100 mg per serving
Interaction report

Kickstart RX by AMMO American Muscle Mass Optimization Drug Interactions

Want to check YOUR meds against Kickstart RX?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
4Drugs
4 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Kickstart RX with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Androst-3, 5-dien-7, 17-dione1 drug type · 4 drugs

Aromatase Inhibitors

It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors. This interaction could potentially increase the risk of side effects associated with low estrogen levels or from additive side effects, such as an increased risk of liver toxicity. It is recommended to consult with a healthcare provider before combining Arimistane with other aromatase inhibitors to assess the potential risks and benefits.

Likelihood Probable Evidence C
The maker

Brand information

Manufacturer and brand details for Kickstart RX, from the product label.

AMMO American Muscle Mass Optimization

See all AMMO American Muscle Mass Optimization products
Name
AMMO
Phone Number
808-623-7887
Pharmacist Counseling Corner

Kickstart RX by AMMO American Muscle Mass Optimization: Common Questions

Does Kickstart RX by AMMO American Muscle Mass Optimization interact with any medications?
Yes. Based on its ingredients, Kickstart RX has a known interaction with 4 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kickstart RX contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Arimistane is rated Possibly Unsafe in pregnancy — lowering estrogen during pregnancy could be harmful. Both Arimistane and Fadogia Agrestis lack safety data in breastfeeding and should be avoided. Talk to your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing.
What is Arimistane supposed to do?
It's marketed as a compound that modulates estrogen by blocking an enzyme called aromatase. The idea is that lowering estrogen might support muscle or athletic gains, but we don't have solid evidence backing that claim.
Does this actually work for muscle or athletic performance?
The evidence isn't established. We hold insufficient reliable evidence to rate Arimistane or Fadogia Agrestis for athletic performance or muscle strength — meaning the studies either aren't there or don't clearly show a benefit.
What are the known side effects?
No adverse effects from human trials are reported in our data. However, Fadogia Agrestis has animal evidence suggesting possible toxicity to the testicles, liver, and kidneys, and Arimistane is a poorly studied hormone-altering drug — so risks may exist even if they haven't been formally documented yet.
Is it safe for men?
Safety data in men are limited. The hormone-altering mechanism and animal signals of testicular toxicity from Fadogia Agrestis are reasons to be cautious and discuss this with your doctor before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kickstart RX label
Sources

Sources & How We Checked

Kickstart RX's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Arimistane 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Arimistane monograph →

Fadogia Agrestis 2 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Fadogia Agrestis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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