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Dietary supplement

Kid-e-Soothe Ingredients & Drug Interactions

by Dr. Christopher's Original Formulas

Kid-e-Soothe label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kid-e-Soothe against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kid-e-Soothe is a dietary supplement by Dr. Christopher's Original Formulas with 2 active ingredients. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 2,140 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kid-e-Soothe by Dr. Christopher's Original Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Kid-e-Soothe by Dr. Christopher's Original Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kid-e-Soothe by Dr. Christopher's Original Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Kid-e-Soothe contains 2 active herbal ingredients: astragalus and marshmallow. Astragalus is a root traditionally used to support immune and general wellness; marshmallow is an herb with mucilage that's thought to soothe inflamed tissues, particularly in the digestive and respiratory tracts.

The product also includes a base and natural flavoring as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: calms and strengthens body's immune responses.
  • We looked for evidence on: Respiratory tract infections, Upper respiratory tract infection (URTI), Fever, immune function, immune response modulation, infection prevention.
  • The closest evidence on file: Marshmallow is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Marshmallow is rated "Insufficient Reliable Evidence To Rate" for Fever.
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Upper respiratory tract infection (URTI).

The data we hold shows insufficient reliable evidence to establish how well either astragalus or marshmallow works for the conditions they're traditionally used for — hay fever, respiratory infections, diarrhea, eczema, and others are all listed as having insufficient evidence in our records. This doesn't mean they don't work, only that the evidence isn't solid enough yet for us to rate them.

The evidence, ingredient by ingredient Astragalus Marshmallow

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both astragalus and marshmallow are generally well tolerated for short-term use in healthy adults, though human safety data are limited. Astragalus has been associated with dizziness and, in rare cases with intravenous dosing, rash or palpitations, though it's unclear whether astragalus caused these or another factor did.

We don't hold adverse-effect data for marshmallow. For pregnancy and breastfeeding, the safety data for both ingredients are too limited to know either way.

The facts advise against use during pregnancy and while breastfeeding. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before using this product.

Side effects, ingredient by ingredient Astragalus Marshmallow

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Marshmallow, Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 2,141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Pause before using this product if your child takes lithium, immunosuppressants, cyclophosphamide, or antidiabetes drugs. Both ingredients raise concerns with lithium in particular.

Also flag any oral medications your child is regularly taking, since marshmallow's mucilage may interfere with their absorption—and if you do use this product alongside oral meds, space them 30–60 minutes apart. Talk with your pharmacist before combining.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Kid-e-Soothe may appeal to parents looking for a herbal liquid for their children, but it's not a good fit if your child takes lithium, immunosuppressants, chemotherapy, or blood thinners—or if you need to space it carefully around oral medications. Before giving this to your child, check with your child's doctor or pharmacist, especially if they're on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kid-e-Soothe, straight from the product label.

Brand Dr. Christopher's Original Formulas
Barcode (UPC) 084783447054
Net contents 2 fl. Oz.
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200424
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kid-e-Soothe by Dr. Christopher's Original Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
15 Drop(s)
Servings per container
114
UPC/BARCODE
084783447054
IngredientAmount% DV
Astragalus0 NP--
Marshmallow0 NP--
Proprietary Blend0 NP--

Other ingredients: A base of, Natural flavoring

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Kid-e-Soothe: Great tasting Immune Calmant.

Suggested/Recommended/Usage/Directions

Recommendations: Shake well. Take 10-15 drops three times a day or every hour as needed.

General Statements

Kid-e-Soothe is an herbal formula which calms and strengthens the body's immune responses.

Immune Calmant

Extract

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. It is not intended to diagnose or treat disease.

Precautions

Seek the advice of a health professional for serious illness.

Formulation

Contains no alcohol.

Brand IP Statement(s)

2006 Wholistic Botanicals All Rights Reserved

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kid-e-Soothe by Dr. Christopher's Original Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kid-e-Soothe label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kid-e-Soothe by Dr. Christopher's Original Formulas

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Servings per container114 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: A base of, Natural flavoring. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kid-e-Soothe by Dr. Christopher's Original Formulas Drug Interactions

Want to check YOUR meds against Kid-e-Soothe?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,140Drugs
208 Moderate 1,932 Minor

Ingredients driving the most interactions

Marshmallow 2,040
Astragalus 208

Individual Drug Interactions

The ingredients in Kid-e-Soothe interact with 2,140 drugs. Click any drug to see the details.

2 of the 2 ingredients in Kid-e-Soothe interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Astragalus

Each ingredient & the kinds of drugs it affects

For each ingredient in Kid-e-Soothe with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kid-e-Soothe, from the product label.

Dr. Christopher's Original Formulas

See all Dr. Christopher's Original Formulas products
Name
Wholistic Botanicals
City
Spanish Fork
State
UT
ZipCode
84660
Web Address
www.drchristopher.com
Pharmacist Counseling Corner

Kid-e-Soothe by Dr. Christopher's Original Formulas: Common Questions

Does Kid-e-Soothe by Dr. Christopher's Original Formulas interact with any medications?
Yes. Based on its ingredients, Kid-e-Soothe has a known interaction with 2,140 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kid-e-Soothe contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my child if they're on diabetes medication?
Astragalus in this product may theoretically lower blood sugar further, raising the risk of dangerously low blood sugar if combined with diabetes drugs. Talk with your child's doctor or pharmacist before using it.
Is this product safe during pregnancy or breastfeeding?
No. The safety data for both astragalus and marshmallow are too limited during pregnancy and breastfeeding. The facts advise against use in both. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before using this product.
What does marshmallow do in this formula?
Marshmallow is an herb with mucilage that's traditionally used to soothe inflamed tissues in the digestive and respiratory tracts. However, the evidence is insufficient to establish how well it actually works.
Are there fillers or other ingredients I should know about?
The product contains a base and natural flavoring as inactive ingredients. The two active ingredients are astragalus and marshmallow.
Why can't I take this at the same time as my other medications?
Marshmallow contains mucilage that may slow or reduce how your body absorbs oral medications. Spacing this product 30–60 minutes after taking other oral drugs helps avoid that interference.
Does this product work for colds or cough?
The evidence we hold is insufficient to establish whether astragalus or marshmallow reliably help with respiratory infections or cough. Talk with your doctor or pharmacist if you're considering this for that purpose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kid-e-Soothe label
Go deeper

The Full Monographs Behind Kid-e-Soothe’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph →
Sources

Sources & How We Checked

Kid-e-Soothe's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.

See these in context on the Marshmallow monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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