Breathe Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Breathe Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Breathe Extract is a dietary supplement by Host Defense Mushrooms with 4 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 502 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Reishi (Ganoderma lucidum s.l.) mycelium extract, fresh Chaga (Inonotus obliquus) mycelium extract, fresh Cordyceps mycelium extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Breathe Extract by Host Defense Mushrooms
Ask about any prescription or over-the-counter medication and we check it for interactions with Breathe Extract by Host Defense Mushrooms — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Breathe Extract by Host Defense Mushrooms
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 4 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1 mL) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 3 of the 3 matched ingredients can interact with medications — Cordyceps, Reishi Mushroom, Chaga.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
- For scale: 502 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 3 of 3.
- General safety write-ups exist for 3 of 3.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Breathe Extract, straight from the product label.
| Brand | Host Defense Mushrooms |
|---|---|
| Net contents | 1 fl. Oz.; 30 mL |
| Market status | Off market |
| Date entered into DSLD | Jan 23, 2015 |
| DSLD ID | 41060 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Breathe Extract by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1 mL | -- |
| fresh Chaga (Inonotus obliquus) mycelium extract | 0 NP | -- |
| fresh Cordyceps mycelium extract | 0 NP | -- |
| fresh Reishi (Ganoderma lucidum s.l.) mycelium extract | 0 NP | -- |
| dried Reishi (Ganoderma lucidum s.l.) fruit body extract | 0 NP | -- |
Other ingredients: Water, Alcohol, myceliated Brown Rice
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Directions for Use: As a dietary supplement, take 1 mL twice per day. Can be taken with food or without, on an empty stomach or as recommended by your healthcare advisor.
MUSHROOMS(TM)
Precautions
Consult your healthcare advisor regarding the use of this product during pregnancy.
Keep out of reach of children.
Formula
MADE WITH U.S. GROWN, TRIPLE EXTRACTED ORGANIC MUSHROOMS
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
USDA ORGANIC
PRODUCER Certified Organic Washington State Dept. of Agriculture
General Statements
HEALTHY RESPIRATORY SUPPORT
PAUL STAMETS
FDA Statement of Identity
DIETARY SUPPLEMENT
Formulation
Certified Organic by the Washington State Department of Agriculture.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Breathe Extract by Host Defense Mushrooms label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Breathe Extract by Host Defense Mushrooms
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Water, Alcohol, Myceliated Brown Rice. These complete the product’s ingredient list but are not active constituents.
Breathe Extract by Host Defense Mushrooms Drug Interactions
Breathe Extract contains 4 ingredients, and 3 of them have known drug interactions. Altogether they interact with 502 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Breathe Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Breathe Extract interact with 502 drugs. Click any drug to see the details.
3 of the 4 ingredients in Breathe Extract interact with drugs. Each result below shows which ingredient is responsible. fresh Reishi (Ganoderma lucidum s.l.) mycelium extract fresh Chaga (Inonotus obliquus) mycelium extract fresh Cordyceps mycelium extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + 6-mercaptopurine interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Abciximab interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Abciximab interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Abrocitinib interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Abrocitinib interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acarbose interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Breathe Extract — through 1 ingredient. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acenocoumarol interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Acenocoumarol interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acetaminophen, Aspirin interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetaminophen, Aspirin interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Acetaminophen, Aspirin, Caffeine interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acetaminophen, Aspirin, Caffeine interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Acetaminophen, Ibuprofen interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acetaminophen, Ibuprofen interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Breathe Extract — through 1 ingredient. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetohexamide interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Acetylsalicylic Acid interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Acetylsalicylic Acid interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-adaz interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-adbm interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-afzb interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-atto interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-bwwd interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Adalimumab-fkjp interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Albiglutide interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Alefacept interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alemtuzumab interactionFresh Cordyceps Mycelium ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Fresh Cordyceps Mycelium Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Breathe Extract — through 1 ingredient. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alogliptin interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Alogliptin, Metformin interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Breathe Extract — through 2 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alogliptin, Pioglitazone interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Alteplase, Tpa interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Alteplase, Tpa interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionFresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Breathe Extract — through 3 ingredients. Tap an ingredient for the detail:
Fresh Cordyceps Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fresh Cordyceps Mycelium Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionDried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionFresh Chaga (inonotus Obliquus) Mycelium ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Fresh Chaga (inonotus Obliquus) Mycelium Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Breathe Extract — through 1 ingredient. Tap an ingredient for the detail:
Dried Reishi (ganoderma Lucidum S.l.) Fruit Body ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Dried Reishi (ganoderma Lucidum S.l.) Fruit Body Extract + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Breathe Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
fresh Reishi (Ganoderma lucidum s.l.) mycelium extract
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
fresh Chaga (Inonotus obliquus) mycelium extract
Anticoagulant/Antiplatelet Drugs
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.
Immunosuppressants
Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.
fresh Cordyceps mycelium extract
Anticoagulant/Antiplatelet Drugs
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.
Testosterone
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.
Brand information
Manufacturer and brand details for Breathe Extract, from the product label.
Host Defense Mushrooms
See all Host Defense Mushrooms products- Name
- Fungi Perfecti, LLC
- Street Address
- PO Box 7634
- City
- Olympia
- State
- WA
- ZipCode
- 98507
Breathe Extract by Host Defense Mushrooms: Common Questions
Does Breathe Extract by Host Defense Mushrooms interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Breathe Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Breathe Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chaga
Interacts with 327 drugsChaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...
Read the full Chaga monograph → Herb & supplement monographCordyceps
Interacts with 249 drugsCordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...
Read the full Cordyceps monograph → Herb & supplement monographReishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph →Sources & How We Checked
Breathe Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chaga 9 references
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
- Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
- Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
- Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
- Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
- Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
- Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed
Cordyceps 14 references
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
- Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
- Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
- Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
- Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
- Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
- Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
- Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
- Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
- Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
- Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
- Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
- Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
- Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
- Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
- Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
- Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
- Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
- Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
- Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
- Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
- Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
- Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
- Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC