Kids Chewable Vitamin C Fruit Punch Natural Flavor Ingredients & Drug Interactions
by Nutrilite
What is this page for?
First and foremost: checking Kids Chewable Vitamin C Fruit Punch Natural Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Kids Chewable Vitamin C Fruit Punch Natural Flavor is a dietary supplement by Nutrilite with 2 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 207 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, Acerola concentrate blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite
Ask about any prescription or over-the-counter medication and we check it for interactions with Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: vitamin C and acerola concentrate blend. Vitamin C is a nutrient your body needs to build connective tissue, support your immune system, and act as an antioxidant.
Acerola is a tropical fruit concentrate that also contains vitamin C. The rest of the tablet is made up of inactive ingredients—fillers, binders, and flavoring—including sorbitol, fructose, maltodextrin, microcrystalline cellulose, and magnesium stearate.
Does it work?
Moderate evidence
Vitamin C is effective for preventing and treating vitamin C deficiency, and there is possibly effective evidence it may help with anemia of chronic disease, cataracts, atrial fibrillation, and exercise-induced respiratory infections. For acerola concentrate, the evidence is more limited: it is possibly effective for vitamin C deficiency, but for common cold, atherosclerosis, and diarrhea, the evidence is insufficient to rate whether it works.
How safe is it?
Well-documented data
Vitamin C from this chewable is generally well tolerated at normal doses. The safety notes advise that normal dietary amounts and amounts in prenatal vitamins are fine, but you should avoid high-dose supplements unless your doctor recommends them.
At very high doses—above 2 grams daily—vitamin C can cause stomach cramps, heartburn, diarrhea, nausea, or headache, and in people prone to kidney stones, it may increase that risk. Acerola is generally considered safe in food amounts or as directed on the label, though concentrated supplements are less well studied.
There is one case report of an allergic reaction (rash, shortness of breath, fast heartbeat) in someone with latex sensitivity, and large doses could theoretically cause osmotic diarrhea. For pregnancy and lactation, vitamin C is rated Likely Safe at normal amounts but Possibly Unsafe at high doses—talk with your doctor before using concentrated supplements during pregnancy or while breastfeeding.
Safety data for acerola in pregnancy and lactation is not on file.
Meds to double-check
Moderate interaction found
Before giving this product, double-check with your child's doctor or pharmacist if they take birth control pills or hormone replacement therapy (estrogen interaction—Moderate), blood thinners like warfarin (Moderate), chemotherapy drugs such as cyclophosphamide or doxorubicin (Moderate), thyroid medication levothyroxine (Moderate), or aluminum-containing antacids (Moderate). Acerola's vitamin C content is dilute, so its interactions with blood thinners, aspirin, and aluminum are considered less clinically significant, but the theoretical risk remains.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This vitamin C chewable is a straightforward way to support your child's vitamin C intake and may help with certain conditions, but it can interact meaningfully with birth control pills, blood thinners, chemotherapy, and several other medications. If your child takes any prescription or over-the-counter drugs, check your medications against the tool on this page and discuss the product with your doctor or pharmacist before starting.
Keep doses normal—very high amounts aren't appropriate for children and can cause stomach upset.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Kids Chewable Vitamin C Fruit Punch Natural Flavor, straight from the product label.
| Brand | Nutrilite |
|---|---|
| Barcode (UPC) | A5353 |
| Net contents | 180 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Apr 22, 2021 |
| DSLD ID | 246512 |
| Product type | Botanical With Nutrients |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years), Kosher, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 0 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | -- |
| Vitamin C | 30 mg | 33% |
| Acerola concentrate blend | 274 mg | -- |
Other ingredients: Sorbitol, Fructose, Dextrose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Citric Acid, natural Fruit Punch flavor, Magnesium Stearate, Maltodextrin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Nutrilite Kids Chewable Vitamin C makes nutrition fun for kids!
Quality you can trust since 1934
Exclusively from Amway
Formula
Each tablet contains 30 mg of vitamin C, which comes from the exclusive Nutrilite Acerola Concentrate. Acerola cherries are one of the richest known natural sources of vitamin C. Vitamin C is a factor in the normal development and maintenance of gums, cartilage, bones and teeth.
Star-K Kosher
Crescent M Halal
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Keep bottle tightly closed Store in a cool, dry place
Formulation
No artificial colors, flavors or preservatives added.
Support your immune system
Precautions
Keep out of reach of children
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
1 tablet, up to 4x a day Suggested Use: One to four tablets daily for adults and children 4 years and over.
Brand IP Statement(s)
Alticor Inc.
Seals/Symbols
Star-K Kosher Crescent M Halal NSF Contents Certified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin C
Interacts with207 drugs
Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...
Vitamin C monograph & interactionsAcerola concentrate blend
Interacts with128 drugs
Acerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and an...
Acerola concentrate blend monograph & interactionsOther (inactive) ingredients: Sorbitol, Fructose, Dextrose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Citric Acid, Natural Fruit Punch flavor, Magnesium Stearate, Maltodextrin. These complete the product’s ingredient list but are not active constituents.
Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite Drug Interactions
HelloPharmacist Interaction Report
Nutrilite Kids Chewable Vitamin C Fruit Punch can interact with medications through its vitamin C and acerola concentrate blend content.
The most serious documented interaction is Moderate severity: vitamin C may increase estrogen levels by up to 55% when taken with birth control pills or hormone replacement therapy, potentially raising the strength of those hormones in your bloodstream.
Read the full breakdown — every affected drug type, severity by severity
Vitamin C also has Moderate interactions with blood thinners like warfarin—high doses can reduce how well the drug works—and with certain chemotherapy drugs (alkylating agents and antitumor antibiotics), where its antioxidant effects might theoretically weaken the cancer treatment. It can also increase aluminum absorption from aluminum-containing compounds, affect thyroid medication (levothyroxine) absorption, and theoretically lower levels of some psychiatric and HIV medications.
Acerola concentrate has similar Moderate interactions with chemotherapy drugs, but its vitamin C content is considered too dilute to produce clinically significant effects with blood thinners, aspirin, aluminum compounds, or warfarin—though the interaction remains theoretical. Acerola also carries Minor interactions with estrogens, though again through its vitamin C content.
Alto gether, these interactions span 207 individual medications. Use the medication checker on this page to see if any of your prescriptions or over-the-counter drugs appear, and talk with your doctor or pharmacist before starting this product if you take any of them.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Kids Chewable Vitamin C Fruit Punch Natural Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Kids Chewable Vitamin C Fruit Punch Natural Flavor interact with 207 drugs. Click any drug to see the details.
2 of the 2 ingredients in Kids Chewable Vitamin C Fruit Punch Natural Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin C Acerola concentrate blend
Alginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Alginic Acid, Aluminum Hydroxide interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Alginic Acid, Aluminum Hydroxide interactionAltretamineHexalen
How Altretamine interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Altretamine interactionAcerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Acetate, Benzethonium Chloride interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Chloride interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAcerola Concentrate BlendAspirin, Aluminum Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate Blend + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAcerola Concentrate BlendAspirin, Aluminum Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate Blend + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Calcium interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium (otc Drug) interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium Hydroxide (otc Drug) interactionAcerola Concentrate BlendAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate Blend + Aluminum, Magnesium Hydroxide (otc Drug) interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAcerola Concentrate BlendAspirin, Aluminum Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate Blend + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Bazedoxifene Acetate, Conjugated Estrogens interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Bazedoxifene Acetate, Conjugated Estrogens interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Acerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Bendamustine interactionVitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Bendamustine Hydrochloride interactionAcerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Bendamustine Hydrochloride interactionBleomycinBlenoxane
How Bleomycin interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAntitumor Antibiotics Moderate
Interaction Summary
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
Read the full Vitamin C + Bleomycin interactionAcerola Concentrate BlendAntitumor Antibiotics Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Read the full Acerola Concentrate Blend + Bleomycin interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Acerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Busulfan interactionVitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Carboplatin interactionAcerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Acerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Carmustine interactionVitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Chlorambucil interactionAcerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Cisplatin interactionAcerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Cisplatin interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Conjugated Estrogens interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Conjugated Estrogens, Medroxyprogesterone Acetate interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Conjugated Estrogens, Meprobamate interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Conjugated Estrogens, Methyltestosterone interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Conjugated Estrogens, Methyltestosterone interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Acerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Cyclophosphamide interactionVitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Cyclophosphamide interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Cyproterone Acetate, Ethinyl Estradiol interactionAcerola Concentrate BlendEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate Blend + Cyproterone Acetate, Ethinyl Estradiol interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Acerola Concentrate BlendAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Read the full Acerola Concentrate Blend + Dacarbazine interactionVitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Dacarbazine interactionDactinomycinCosmegan, Cosmegen
How Dactinomycin interacts with Kids Chewable Vitamin C Fruit Punch Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAntitumor Antibiotics Moderate
Interaction Summary
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
Read the full Vitamin C + Dactinomycin interactionAcerola Concentrate BlendAntitumor Antibiotics Moderate
Interaction Summary
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Read the full Acerola Concentrate Blend + Dactinomycin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Kids Chewable Vitamin C Fruit Punch Natural Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin C
Alkylating Agents
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Aluminum
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.
Antitumor Antibiotics
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.
Estrogens
Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.
Fluphenazine (Prolixin)
Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.
Indinavir (Crixivan)
Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.
Levothyroxine (Synthroid, Others)
Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.
Warfarin (Coumadin)
High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.
Acetaminophen (Tylenol, Others)
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.
Aspirin
Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.
Choline Magnesium Trisalicylate (Trilisate)
Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Niacin
Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.
Salsalate (Disalcid)
Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Acerola concentrate blend
Alkylating Agents
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as alkylating agents. In contrast, other researchers theorize that antioxidants might make alkylating chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Antitumor Antibiotics
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.
Aluminum
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Acerola contains vitamin C. It is thought that vitamin C chelates aluminum, keeping it in solution and available for absorption. In people with normal renal function, urinary excretion of aluminum likely increases, making aluminum retention and toxicity unlikely. However, patients with renal failure who take aluminum-containing compounds, such as phosphate binders, should avoid acerola in doses that provide more vitamin C than the recommended dietary allowances.
Aspirin
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and aspirin is unlikely.
Estrogens
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Acerola contains vitamin C. Increases in plasma estrogen levels of up to 55% have occurred under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.
Warfarin (Coumadin)
Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and warfarin is unlikely.
Brand information
Manufacturer and brand details for Kids Chewable Vitamin C Fruit Punch Natural Flavor, from the product label.
Nutrilite
See all Nutrilite products- Name
- Amway Corp.
- City
- Ada
- State
- MI
- ZipCode
- 49355
- Phone Number
- 1-800-253-6500
- Web Address
- Amway.com/Nutrilite
Kids Chewable Vitamin C Fruit Punch Natural Flavor by Nutrilite: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Kids Chewable Vitamin C Fruit Punch Natural Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin C
Interacts with 207 drugsVitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...
Read the full Vitamin C monograph → Herb & supplement monographAcerola
Interacts with 128 drugsAcerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and antioxidants. While vitamin C itself has w...
Read the full Acerola monograph →Sources & How We Checked
Kids Chewable Vitamin C Fruit Punch Natural Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 71 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin C 51 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
- Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
- Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
- Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
- Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
- Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
- Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
- Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
- Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
- Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
- Dysken MW, Cumming RJ, Channon RA, Davis JM. Drug interaction between ascorbic acid and fluphenazine. JAMA 1979;241:2008. DOI
- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Slain D, Amsden JR, Khakoo RA, et al. Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers. Pharmacotherapy 2005;25:165-70. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
- Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
- Lee DH, Folsom AR, Harnack L, et al. Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am J Clin Nutr 2004;80:1194-200. PubMed
- Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32. PubMed
- Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Fairweather-Tait S, Hickson K, McGaw B, et al. Orange juice enhances aluminium absorption from antacid preparation. Eur J Clin Nutr. 1994;48(1):71-3.
- Gruenwald, J., Graubaum, H. J., Busch, R., and Bentley, C. Safety and tolerance of ester-C compared with regular ascorbic acid. Adv.Ther. 2006;23(1):171-178.
- Rahimi, R., Nikfar, S., Rezaie, A., and Abdollahi, M. A meta-analysis on the efficacy and safety of combined vitamin C and E supplementation in preeclamptic women. Hypertens.Pregnancy. 2009;28(4):417-434. PubMed
- Einerson, B., Nathorn, C., Kitiyakara, C., Sirada, M., and Thamlikitkul, V. The efficacy of ascorbic acid in suboptimal responsive anemic hemodialysis patients receiving erythropoietin: a meta-analysis. J Med.Assoc.Thai. 2011;94 Suppl 1:S134-S146.
- Li, G., Li, L., Yu, C., and Chen, L. Effect of vitamins C and E supplementation on Helicobacter pylori eradication: a meta-analysis. Br.J Nutr 2011;106(11):1632-1637.
- Chen X, Shen L, Gu X, et al. High-dose supplementation with vitamin C--induced pediatric urolithiasis: the first case report in a child and literature review. Urology. 2014;84(4):922-4. PubMed
- Sattar A, Willman JE, Kolluri R. Possible warfarin resistance due to interaction with ascorbic acid: case report and literature review. Am J Health Syst Pharm. 2013;70(9):782-6. PubMed
- Yaich S, Chaabouni Y, Charfeddine K, et al. Secondary oxalosis due to excess vitamin C intake: a cause of graft loss in a renal transplant recipient. Saudi J Kidney Dis Transpl. 2014;25(1):113-6. PubMed
- Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. PubMed
- Rumbold A, Ota E, Nagata C, Shahrook S, Crowther CA. Vitamin C supplementation in pregnancy. Cochrane Database Syst Rev. 2015;(9):CD004072. PubMed
- Seo MS, Kim JK, Shim JY. High-dose vitamin C promotes regression of multiple pulmonary metastases originating from hepatocellular carcinoma. Yonsei Med J. 2015;56(5):1449-52. PubMed
- Skelin M, Lucijanic T, Amidzic Klaric D, et al. Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review. Clin Ther. 2017 Feb;39(2):378-403. PubMed
- Jiang K, Tang K, Liu H, Xu H, Ye Z, Chen Z. Ascorbic acid supplements and kidney stones incidence among men and women: a systematic review and meta-analysis. Urol J. 2019;16(2):115-120.
- Thomas S, Patel D, Bittel B, et al. Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial. JAMA Netw Open. 2 PubMed
- Giffen MA, McLemore JL. Hyperoxalosis Secondary to Intravenous Vitamin C Administration as a Non-Allopathic Treatment for Cancer. Acad Forensic Pathol 2019;9(1-2):118-126. PubMed
- Maike A, Sturgill D, Gallan A. Oxalate Nephropathy in a Renal Transplant Recipient After Receiving High Dose Ascorbic Acid. Am J Med Sci 2021. PubMed
- Shen ZY, Chen YR, Wang MC, Chang SS. High-dose vitamin C-induced acute oxalate nephropathy in a renal transplant recipient: a case report and literature review. Asian J Surg 2022. PubMed
- Yanase F, Spano S, Maeda A, et al. Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial. Crit Care 2023;27(1):371. PubMed
- Sharma Y, Sumanadasa S, Shahi R, et al. Efficacy and safety of vitamin C supplementation in the treatment of community-acquired pneumonia: a systematic review and meta-analysis with trial sequential analysis. Sci Rep 2024;14(1):11846. PubMed
- Pejcic AV, Petrovic NZ, Djordjic MD, Milosavljevic MN. Vitamin C Levels in Pregnant Women and the Efficacy of Vitamin C Supplements in Preventing Premature Rupture of Membranes: A Systematic Review and Meta-Analysis. Balkan Med J 2024;41(4):248-260. PubMed
Acerola 20 references
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
- Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
- Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
- Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
- Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
- Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
- Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
- Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
- Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Denadai R, Souza FM, Valle MR. Fecal impaction by rectal acerola bezoar. Indian J Pediatr 2013;80(5):432-3. PubMed
- Raulf-Heimsoth M, Stark R, Sander I, et al. Anaphylactic reaction to apple juice containing acerola: cross-reactivity to latex due to prohevein. J Allergy Clin Immunol 2002;109(4):715-6. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC