Kiwi Regularity Ingredients & Drug Interactions
by Enzymedica
What is this page for?
First and foremost: checking Kiwi Regularity against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Kiwi Regularity is a dietary supplement by Enzymedica with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,047 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Kiwi, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Kiwi Regularity by Enzymedica
Ask about any prescription or over-the-counter medication and we check it for interactions with Kiwi Regularity by Enzymedica — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Kiwi Regularity by Enzymedica
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
Kiwi Regularity contains 2 active ingredients: kiwi powder and actinidin (an enzyme found in kiwi fruit). The product also includes several inactive ingredients — tapioca dextrose, tapioca maltodextrin, sunflower lecithin, palm oil, guar gum, natural flavors, citric acid, bamboo silica, stevia leaf extract, and monk fruit extract — which serve as fillers, binders, and flavor.
Does it work?
Strong evidence
The evidence we hold on kiwi for constipation, asthma, high blood pressure, and irritable bowel syndrome is insufficient to establish how well it works. That doesn't mean it's ineffective — it means the research available to us hasn't yet proven its benefit for these uses.
Talk to your doctor or pharmacist about whether this product makes sense for your situation.
How safe is it?
Well-documented data
Kiwi eaten as a whole fruit is generally well tolerated. However, concentrated kiwi supplements like this one haven't been well studied, so it's worth checking with your doctor before using a supplement-strength product.
Some people have allergic reactions to kiwi, which can range from mild (itching or swelling of the lips, mouth, tongue, and throat, trouble swallowing, hives, or skin rash) to serious (severe swelling, vomiting, nausea, diarrhea, or in rare cases, severe allergic reaction and breathing problems). If you've never eaten kiwi before or know you have a kiwi allergy, be cautious.
Pregnancy and lactation safety data rates kiwi as likely safe.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (such as aspirin, warfarin, clopidogrel, enoxaparin, or heparin) — kiwi may increase bleeding risk. You should also confirm you're not taking blood pressure medications (such as captopril, enalapril, or losartan) without discussing it first, as kiwi may lower blood pressure further.
The bottom line
Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is a kiwi-based supplement for digestive regularity, but the evidence for how well it works isn't established in the data we hold. If you take blood thinners or blood pressure medications, you'll want to check with your doctor or pharmacist first — kiwi can interact with both.
If you have a kiwi allergy or have never eaten kiwi before, talk it through with your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Kiwi Regularity, straight from the product label.
| Brand | Enzymedica |
|---|---|
| Barcode (UPC) | 670480110157 |
| Net contents | 30 Relief Chew(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 296544 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Kiwi Regularity by Enzymedica, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Carbohydrates | 2 Gram(s) | 1% |
| Added Sugars | 1 Gram(s) | 2% |
| Total Sugars | 2 Gram(s) | -- |
| Dietary Fiber | 1 Gram(s) | 1% |
| Actinidin | 0 NP | -- |
| Kiwi, Powder | 600 mg | -- |
| Actazin | 600 mg | -- |
Other ingredients: Tapioca Dextrose, Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum, Natural Flavors, Citric Acid, Bamboo Silica, Stevia leaf extract, Monk Fruit extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
3x more enzymes vs. Mass Market Brand
Made with a Cold-Press Process Improves Regularity & Supports Digestion Helps relieve occasional constipation Helps reduce gas & bloating
NON GMO
Vegan Dietary Supplement
4 Benefits in 1 Improved Regularity Not a stimulant laxative - kiwi provides general support for your daily regularity needs. Reduced Occasional Constipation Kiwi, naturally containing fibers and polyphenols, has been shown to reduce occasional constipation. Prebiotic Microbiome Boost As a natural prebiotic, kiwi boosts the good bacteria in your GI tract to improve your overall digestive performance.
Natural speckling may occur.
CONTAINS NO: Gluten, milk, casein, soy, egg, artificial colors or flavors.
Not Just Any Kiwi Grown in the pristine orchards of the kiwifruit capital of the world, Te Puke, New Zealand, the organic kiwifruit in Actazin are nutrient dense and renowned for their unique ability to support regular bowel movements and help alleviate occasional constipation, bloating and gas. Actazin organic kiwifruit powder is made by filtering kiwis through a proprietary cold-press process to preserve nutrients and is clinically studied to support digestive & bowel health.
Brand IP Statement(s)
Enzymedica Natural Digestive Health & Wellness
Actazin is a registered trademark of Anagenix IP Ltd.
Formula
15+ kiwis in every bottle Made with clinically studied Actazin Kiwifruit Kiwi flavor
Better Digestion A natural enzyme from kiwi, actinidin, helps break down protein in food, making it easier to digest.
FDA Statement of Identity
Vegan Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Recommended Use: Chew 2 relief chews daily. More may be taken as needed, not to exceed 6 daily.
General Statements
Enzymedica is a proud member of RSPO and supports the use of sustainable palm oil.
Why Enzymedica? Ours Competing Mass Market Brand Serving Size 2 Relief Chews 2 Tablets Enzymes per serving 15,000 Units 4,140 Units Artificial Ingredients No Yes Real Kiwis - per bottle 15+ ?
Precautions
Please keep out of reach of children.
Do not use if safety seal is broken or missing.
Storage
Keep closed in dry place; avoid excessive heat.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Kiwi Regularity by Enzymedica label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Kiwi Regularity by Enzymedica
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Relief Chew(s) Dosage formOther (e.g. Tea Bag) Servings per container15 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsKiwi, Powder
Interacts with289 drugs
Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is fo...
Kiwi, Powder monograph & interactionsActazin
Interacts with289 drugs
Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is fo...
Actazin monograph & interactions- › Actinidin
Other (inactive) ingredients: Tapioca Dextrose, Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum, Natural Flavors, Citric Acid, Bamboo Silica, Stevia leaf extract, Monk Fruit extract. These complete the product’s ingredient list but are not active constituents.
Kiwi Regularity by Enzymedica Drug Interactions
HelloPharmacist Interaction Report
Kiwi Regularity by Enzymedica contains kiwi powder, which has documented interactions with two major drug categories.
The most serious concern is with blood thinners and antiplatelet drugs (such as aspirin, warfarin, clopidogrel, and enoxaparin): kiwi may inhibit platelet aggregation and increase bleeding risk when combined with these medications.
Read the full breakdown — every affected drug type, severity by severity
The product also interacts with blood pressure medications (antihypertensives like captopril, enalapril, and losartan). Kiwi can lower blood pressure, and using it alongside these drugs may cause your blood pressure to drop too far (low blood pressure).
Altogether, these interactions span 289 individual medications.
We could not check one ingredient — actinidin — because interaction data isn't on file for it. Before you start this product, run your exact medications through the checker below, especially if you take any blood thinner or blood pressure medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Kiwi Regularity?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Kiwi Regularity interact with 2,047 drugs. Click any drug to see the details.
2 of the 3 ingredients in Kiwi Regularity interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Kiwi, Powder
ArgatrobanArgatroban
How Argatroban interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Argatroban interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Butalbital, Caffeine, Phenacetin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Dover's Pwd interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Hydrocodone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Orphenadrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Carisoprodol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Carisoprodol, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Citric Acid, Sodium Bicarbonate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Codeine Phosphate, Methocarbamol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Codeine Phosphate, Phenobarbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Diphenhydramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Dipyridamole interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Ethoheptazine, Meprobamate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Hydrocodone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Meprobamate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Methocarbamol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Kiwi Regularity — through 2 ingredients. Tap an ingredient for the detail:
ActazinAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Clinical research suggests that kiwi inhibits platelet aggregation.
Read the full Actazin + Aspirin, Omeprazole interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aspirin, Omeprazole interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Kiwi Regularity with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Kiwi, Powder
Anticoagulant/Antiplatelet Drugs
Clinical research suggests that kiwi inhibits platelet aggregation. Theoretically, kiwi might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Antihypertensive Drugs
Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals. Theoretically, concomitant use of kiwi and antihypertensive drugs may increase the risk of hypotension when used in combination with drugs that lower blood pressure. These include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Brand information
Manufacturer and brand details for Kiwi Regularity, from the product label.
Enzymedica
See all Enzymedica products- Name
- Enzymedica, Inc.
- Street Address
- 771 Commerce Drive
- City
- Venice
- State
- FL
- ZipCode
- 34292-1731
- Phone Number
- 1-888-918-1118
- Web Address
- www.enzymedica.com
Kiwi Regularity by Enzymedica: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Kiwi Regularity is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Kiwi Regularity’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographKiwi
Interacts with 289 drugsKiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is for helping with constipation and overall...
Read the full Kiwi monograph →Sources & How We Checked
Kiwi Regularity's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 50 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Kiwi 32 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
- Forastiere F, Pistelli R, Sestini P, et al. Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. Thorax 2000;55:283-8. DOI
- Carey IM, Strachan DP, Cook DG. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998;158:728-33. PubMed
- Schwartz J, Weiss ST. Relationship between dietary vitamin C intake and pulmonary function in the First National Health and Nutrition Examination Survey (NHANES I). Am J Clin Nutr 1994;59:110-4. PubMed
- Butland BK, Fehily AM, Elwood PC. Diet, lung function, and lung function decline in a cohort of 2512 middle aged men. Thorax 2000;55:102-8. PubMed
- Troisi RJ, Willett WC, Weiss ST, et al. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401-8. PubMed
- Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
- Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
- Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44. PubMed
- Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97. PubMed
- Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed
- Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed
- Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
- Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed
- Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
- Duttaroy, A. K. and Jorgensen, A. Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers. Platelets. 2004;15(5):287-292. PubMed
- Chan, A. O., Leung, G., Tong, T., and Wong, N. Y. Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients. World J Gastroenterol. 9-21-2007;13(35):4771-4775. PubMed
- Chang, C. C., Lin, Y. T., Lu, Y. T., Liu, Y. S., and Liu, J. F. Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation. Asia Pac.J Clin.Nutr. 2010;19(4):451-457.
- Brevik, A., Gaivao, I., Medin, T., Jorgenesen, A., Piasek, A., Elilasson, J., Karlsen, A., Blomhoff, R., Veggan, T., Duttaroy, A. K., and Collins, A. R. Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effect
- Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244. PubMed
- Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
- Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
- Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160. PubMed
- Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513. PubMed
- Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
- Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222. PubMed
- Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105. PubMed
- Svendsen, M., Klemsdal, T. O., Heggen, E., Holme, I., Pedersen, T. R., Seljeflot, I., Blomhoff, R., and Tonstad, S. Effect of Dietary Intake of Kiwi Fruit on 24-Hour Ambulatory Blood Pressure (Abstract 16175). Circulation 2011;
- Eady SL, Wallace AJ, Hedderley DI, Bentley-Hewitt KL, Butts CA. The effects on immune function and digestive health of consuming the skin and flesh of Zespri SunGold Kiwifruit (Actinidia Chinensis var. Chinensis 'Zesy002') in healthy and IBS-constipated i
- Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30. PubMed
- Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC