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Dietary supplement

Klamath Blue Green Algae 500 mg Ingredients & Drug Interactions

by Wonder Laboratories

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Klamath Blue Green Algae 500 mg is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Klamath Blue Green Algae. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Klamath Blue Green Algae 500 mg by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a single-ingredient product: Klamath Blue Green Algae, a type of cyanobacteria (a freshwater organism with nutrient density). Each capsule delivers 500 mg of the algae itself.

There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Blue-green Algae's overall clinical evidence instead.

Moderate

Some clinical evidence supports Blue-green Algae for:

Why this rating?
  • The label markets general wellness (“General nutrition and nutritional support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hypertension — rated "Possibly Effective" (Natural Medicines).

The evidence for blue-green algae is mixed and often thin. Blood pressure control is rated possibly effective — meaning some evidence suggests it may help, but more research is needed.

For acne, hay fever, iron deficiency anemia, and arsenic poisoning, the evidence is insufficient to know whether it works. We don't have enough reliable data on those uses yet.

The evidence, ingredient by ingredient Blue-green Algae

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue-green algae are generally well tolerated by mouth, but a few things matter here. The most common side effects are digestive — abdominal cramps, bloating, diarrhea, nausea, vomiting, flatulence — plus dizziness, fatigue, and headache.

Allergic reactions are rare but serious: rashes and itching can occur, and one case of anaphylaxis (a life-threatening allergic reaction) with throat swelling and asthma has been reported. A handful of patients have had mild gum bleeding or bruising.

There's also a quality and contamination concern. Not all blue-green algae products are made equally; some can contain toxins or heavy metals.

The safety data for pregnancy and lactation aren't on file, so you'll want to talk with your doctor or pharmacist if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Blue-green Algae

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blue-green Algae.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin), drugs that suppress your immune system, or diabetes medications. These are the main interactions we've documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product might be worth trying if you're interested in natural blood pressure support and have no medications that interact with blood thinners, immune-suppressing drugs, or diabetes medication. Talk with your pharmacist before starting, especially if you're on any prescriptions or if you've had allergic reactions to supplements in the past.

Quality varies between brands, so stick with reputable manufacturers.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klamath Blue Green Algae 500 mg, straight from the product label.

Brand Wonder Laboratories
Barcode (UPC) 099528343102
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 315207
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klamath Blue Green Algae 500 mg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
099528343102
IngredientAmount% DV
Klamath Blue Green Algae500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 capsule three times daily.

Formula

Klamath Blue Green Algae contains a full spectrum of 12 vitamins, including vitamin B-12 and Beta Carotene, and 23 minerals. A rich nutritional food, it contains large amounts of high quality protein, with a complement of essential amino acids. Klamath Blue Green Algae is harvested from May to October on a daily basis, fresh from the Upper Klamath Lake, a fresh water lake fed by rivers and underground springs which provide a mineral rich reservoir for the algae. Once harvest it is flash frozen to preserve its vital nutrients.

Ko Kosher Service

Wildcrafted, fresh water algae from upper Klamath Lake. Cultivated in an environment free of pesticides and pollutants. Enzyme enhanced with plant source enzymes (protease, cellulase, amylase and lipase). Aphanizomenon is an ancient strain of cyanobacteria with a high concentration of chlorophyll, vitamins, minerals, protein and amino acids.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Storage

Keep tightly closed. Store at room temperature: 59 Degrees - 86 Degrees F (15 Degrees to 30 Degrees C).

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Gluten free

Conforms to USP < 2091 > for weight. Meets USP < 2040 > disintegration for maximum bioavailability. Made in USA

General Statements

Formula 343

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Ko Kosher Service

See for yourself

Klamath Blue Green Algae 500 mg by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Klamath Blue Green Algae 500 mg by Wonder Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Klamath Blue Green Algae

Interacts with
327 drugs
500 mg per serving

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...

Klamath Blue Green Algae monograph & interactions
Interaction report

Klamath Blue Green Algae 500 mg by Wonder Laboratories Drug Interactions

Want to check YOUR meds against Klamath Blue Green Algae 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Klamath Blue Green Algae 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Klamath Blue Green Algae3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D
Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Klamath Blue Green Algae 500 mg, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Klamath Blue Green Algae 500 mg by Wonder Laboratories: Common Questions

Does Klamath Blue Green Algae 500 mg by Wonder Laboratories interact with any medications?
Yes. Based on its ingredients, Klamath Blue Green Algae 500 mg has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klamath Blue Green Algae 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
You need to talk with your pharmacist first. Blue-green algae can thin the blood in lab tests, and there's a Moderate-level interaction with blood thinners. One small study found the real-world risk was unlikely, but it's not zero. Your pharmacist can review your dose and timing.
What are the most common side effects?
Digestive issues top the list: bloating, cramps, diarrhea, nausea, and gas. You might also feel dizzy, tired, or get a headache. These are usually mild, but if they don't fade, cut back or stop.
Is this safe if I'm pregnant or breastfeeding?
We don't have enough safety data on file for pregnancy or lactation. You'll want to talk with your doctor or pharmacist before taking it if you're pregnant, trying to conceive, or nursing.
Does this actually lower blood pressure?
The evidence suggests it possibly can, but we don't have a lot of research yet. It's rated possibly effective for hypertension, meaning some data point that way, but we need more proof.
Can this cause an allergic reaction?
Allergic reactions are rare, but they do happen. Most are mild rashes or itching. One serious case of anaphylaxis—throat swelling, hives, and asthma—was reported. If you get a rash, itching, swelling, or trouble breathing, stop and seek help right away.
Should I worry about contamination?
Yes. Blue-green algae quality varies widely, and some products have been contaminated with toxins or heavy metals. Buy from a reputable brand you trust.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Klamath Blue Green Algae 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klamath Blue Green Algae 500 mg label
Go deeper

The Full Monographs Behind Klamath Blue Green Algae 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Klamath Blue Green Algae 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue-green Algae 22 references
  1. Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
  2. Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
  3. Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
  4. Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
  5. Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
  6. Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
  7. Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
  8. Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
  9. Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
  10. Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
  11. Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
  12. Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
  13. Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
  14. Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
  15. Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
  16. Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
  17. Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
  18. Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
  19. Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
  20. Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
  21. Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
  22. Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed

See these in context on the Blue-green Algae monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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