Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Klamax Ingredients & Drug Interactions

by iGalen

Klamax label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Klamax against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Klamax is a dietary supplement by iGalen with 4 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 332 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Klamath Microalgae extract, Bamboo sprout extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Klamax by iGalen

Ask about any prescription or over-the-counter medication and we check it for interactions with Klamax by iGalen — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Klamax by iGalen

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Klamax contains 3 active ingredients: Klamath microalgae extract and bamboo sprout extract. The product also contains inactive ingredients — banana juice concentrate, erythritol, vanilla flavor, corn starch, chocolate flavor, citric acid, thaumatin, and stevia leaf extract — which serve as sweeteners, flavor, and binders.

Klamath microalgae is a blue-green algae used in supplements, while bamboo sprout extract comes from the young shoots of bamboo plants. Together they make up the active supplement formula.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“General nutrition and antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Hypertension — rated "Possibly Effective" (Blue-green Algae) (Natural Medicines).

The evidence for Klamath microalgae is limited. It's rated possibly effective for high blood pressure, but the data for acne, hay fever, iron-deficiency anemia, and arsenic poisoning is insufficient to rate.

Bamboo sprout extract is not rated for any condition in the data we hold—the effectiveness evidence simply isn't established.

The evidence, ingredient by ingredient Blue-green Algae Bamboo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Klamath microalgae and bamboo sprout extract are generally well tolerated when taken by mouth, though some people report mild side effects. Common ones with the microalgae include abdominal cramps, bloating, diarrhea, dizziness, fatigue, flatulence, headache, nausea, and vomiting.

Allergic reactions are rare but serious—a few cases of rashes and itching have been reported, and one case of anaphylaxis (a severe allergic reaction) occurred in a teenager. There's an important quality concern: Klamath microalgae products can be contaminated with toxins or heavy metals, and safety data on concentrated bamboo extract supplements is limited.

During pregnancy, the safety data advises against using bamboo extract. While breastfeeding, the safety of bamboo extract is unknown—talk with your doctor or pharmacist before using it.

Side effects, ingredient by ingredient Blue-green Algae Bamboo

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bamboo, Blue-green Algae.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 332 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Klamax, double-check these medication types: blood thinners and antiplatelet drugs (Moderate severity), immunosuppressants (Moderate), antidiabetes drugs (Moderate), and antithyroid drugs (Moderate). Altogether, these interactions span 327 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, diabetes medications, drugs that suppress your immune system, or antithyroid drugs, you should check your exact medications with the tool on this page before starting Klamax. Quality and contamination are concerns with this product, so ask your pharmacist about the source and testing.

For pregnant or breastfeeding women, talk with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klamax, straight from the product label.

Brand iGalen
Net contents 2.8 Oz(s); 80 Gram(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 211586
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klamax by iGalen, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Gram(s)
Maximum serving Sizes:
4 Gram(s)
Servings per container
20
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Protein1 Gram(s)1%
Klamath Microalgae extract750 mg--
Klamath Microalgae extract250 mg--
Bamboo sprout extract40 mg--

Other ingredients: dehydrated Banana juice concentrate, Erythritol, natural Vanilla flavor, Corn Starch, natural Chocolate flavor, Citric Acid, Thaumatin, Stevia leaf extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

AFA Botanical Dietary Supplement

Formula

With the proprietary AFA extracts

Brand IP Statement(s)

Aphamax (US Patent NO. 8,337,858) & Klamin (US Patent NO. 9,522,167)

Klamin is a registered trademark of Naturatech S.r.l.

Suggested/Recommended/Usage/Directions

Suggested Use: Adults: Mix one half to one (1/2-1) scoop with a glass of water and consume once or twice daily.

Precautions

Caution: Do not exceed the recommended dose.

Children under the age of 18, pregnant or nursing mothers, and individuals with a known medical condition or who are taking prescription medication should consult a doctor before using this or any dietary supplement.

Children under the age of 18, pregnant or nursing mothers, and individuals with a known medical condition or who are taking prescription medication should consult a doctor before using this or any dietary supplement.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Klamax by iGalen label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Klamax label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Klamax by iGalen

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Klamath Microalgae extract

Interacts with
327 drugs
750 mg per serving

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...

Klamath Microalgae extract monograph & interactions

Klamath Microalgae extract

Interacts with
327 drugs
250 mg per serving

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...

Klamath Microalgae extract monograph & interactions

Bamboo sprout extract

Interacts with
5 drugs
40 mg per serving Form: Silica

Bamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail,...

Bamboo sprout extract monograph & interactions

Other (inactive) ingredients: Dehydrated Banana juice concentrate, Erythritol, Natural Vanilla flavor, Corn Starch, Natural Chocolate flavor, Citric Acid, Thaumatin, Stevia leaf extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Klamax by iGalen Drug Interactions

Want to check YOUR meds against Klamax?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
332Drugs
332 Moderate

Ingredients driving the most interactions

Klamath Microalgae extract 327
Bamboo sprout extract 5

Individual Drug Interactions

The ingredients in Klamax interact with 332 drugs. Click any drug to see the details.

2 of the 4 ingredients in Klamax interact with drugs. Each result below shows which ingredient is responsible. Klamath Microalgae extract Bamboo sprout extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Klamax with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Klamath Microalgae extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D
Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D
Klamath Microalgae extract full monograph & interactions

Bamboo sprout extract1 drug type · 5 drugs

Antithyroid Drugs

Theoretically, long-term bamboo use might increase the effects and adverse effects of antithyroid drugs, possibly leading to hypothyroidism.
Animal research suggests that long-term consumption of bamboo shoot can decrease thyroid peroxidase activity, as well as levels of thyroxine (T4) and triiodothyronine (T3). This effect has not yet been reported in humans.

Likelihood Possible Evidence D
Bamboo sprout extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Klamax, from the product label.

iGalen

See all iGalen products
Name
Blue Lotus S.r.l.
Street Address
Via l Maggetti 14
City
Urbino
State
Italy
ZipCode
61029
Pharmacist Counseling Corner

Klamax by iGalen: Common Questions

Does Klamax by iGalen interact with any medications?
Yes. Based on its ingredients, Klamax has a known interaction with 332 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klamax contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Klamath microalgae, and why is it in this product?
Klamath microalgae is a type of blue-green algae used in supplements. It's included because research suggests it may help with high blood pressure, though the evidence for other uses—like acne or anemia—isn't strong enough to rate.
Can I take this if I'm pregnant?
The safety data for Klamath microalgae in pregnancy isn't established, so there isn't enough information to say yes or no. Bamboo extract specifically should be avoided during pregnancy. Talk with your doctor or pharmacist about whether this product is right for you.
What side effects might I notice?
Most people tolerate it well, but some experience stomach cramps, bloating, diarrhea, dizziness, fatigue, gas, headache, nausea, or vomiting. Allergic reactions are rare but can happen—rashes and itching have been reported in a few cases.
Why does the label mention contamination concerns?
Quality varies between Klamath microalgae products, and some can contain toxins or heavy metals. Ask your pharmacist about where this batch comes from and what testing it's had.
Is this safe to take with my blood pressure medication?
Not without checking first. The Klamath microalgae in this product can theoretically increase bleeding risk if combined with blood thinners or antiplatelet drugs. Use the medication checker on this page with your specific drugs, or call your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klamax label
Go deeper

The Full Monographs Behind Klamax’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blue-green Algae

Interacts with 327 drugs

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...

Read the full Blue-green Algae monograph → Herb & supplement monograph

Bamboo

Interacts with 5 drugs

Bamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail, and bone support. Solid human evidence f...

Read the full Bamboo monograph →
Sources

Sources & How We Checked

Klamax's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue-green Algae 22 references
  1. Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
  2. Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
  3. Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
  4. Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
  5. Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
  6. Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
  7. Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
  8. Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
  9. Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
  10. Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
  11. Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
  12. Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
  13. Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
  14. Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
  15. Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
  16. Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
  17. Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
  18. Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
  19. Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
  20. Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
  21. Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
  22. Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed

See these in context on the Blue-green Algae monograph →

Bamboo 4 references
  1. Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
  2. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
  3. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
  4. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI

See these in context on the Bamboo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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