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Dietary supplement

L-Carnosine 200 mg Ingredients & Drug Interactions

by Kirkman

L-Carnosine 200 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Carnosine 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Carnosine 200 mg is a dietary supplement by Kirkman with 1 active ingredient. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against L-Carnosine 200 mg by Kirkman

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Carnosine 200 mg by Kirkman — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of L-Carnosine 200 mg by Kirkman

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-carnosine, a compound made naturally in your body from two amino acids. The capsule also holds several inactive ingredients—microcrystalline cellulose, hypromellose, water, and silicon dioxide—which are fillers and binders that help form and hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Carnosine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: amino acid supporting brain muscle heart liver kidney.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive impairment, Heart failure, Diabetic nephropathy, hepatic function — and 1 related terms.
  • The closest evidence on file: Carnosine is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Carnosine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cognitive impairment, Heart failure, Diabetic nephropathy.

The evidence for L-carnosine is mixed and limited. Research suggests it's probably not effective for autism spectrum disorder.

For other uses—age-related cognitive decline, Alzheimer disease, athletic performance, cataracts, and general cognitive impairment—we don't have enough reliable data to say whether it works. If you're considering it for one of these reasons, talk with your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Carnosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-carnosine is generally well tolerated in short-term studies, but we don't have solid long-term safety data. Some people have reported decreased appetite, dry mouth, small weight changes, foot and joint pain, and rarely, pneumonia.

The facts advise against use during pregnancy and breastfeeding because there isn't enough safety information—talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing before you take this.

Side effects, ingredient by ingredient Carnosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, or other blood-sugar-lowering medications), check your exact medications with the tool on this page before starting L-carnosine. There's a moderate-severity risk of low blood sugar when combining them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

L-carnosine is a single-ingredient supplement that's generally well tolerated short-term, but long-term safety isn't well established and evidence for most uses is thin or absent. If you take antidiabetes medication, check with your doctor or pharmacist before starting—there's a real risk of your blood sugar dropping too low.

For anyone else, a conversation with your own healthcare provider about whether this makes sense for you is a smart move.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnosine 200 mg, straight from the product label.

Brand Kirkman
Barcode (UPC) 812325020904
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 317731
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnosine 200 mg by Kirkman, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
90
UPC/BARCODE
812325020904
IngredientAmount% DV
L-Carnosine200 mg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Water, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Important: Store in a cool dry place and tightly capped.

Precautions

Keep out of the reach of children. Caution: Formulated for adults and children four years and older. For children under four, consult a physician.

Formulation

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame

Hypoallergenic

Gluten-Free

Brand IP Statement(s)

Kirkman and Ultra Tested are Registered in U.S. Patent and Trademark Office.

Seals/Symbols

Ultra Tested cGMP

Formula

Amino acid that supports brain, muscle, heart, liver, and kidney functions

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take one to four capsules daily or as directed by a physician.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Carnosine 200 mg by Kirkman label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Carnosine 200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Carnosine 200 mg by Kirkman

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

L-Carnosine

Interacts with
86 drugs
200 mg per serving

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Water, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Carnosine 200 mg by Kirkman Drug Interactions

Want to check YOUR meds against L-Carnosine 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

L-Carnosine 86

Individual Drug Interactions

The ingredients in L-Carnosine 200 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in L-Carnosine 200 mg interact with drugs. Each result below shows which ingredient is responsible. L-Carnosine

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnosine 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
L-Carnosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Carnosine 200 mg, from the product label.

Kirkman

See all Kirkman products
Name
Kirkman
City
Lake Oswego
State
OR
ZipCode
97035
Phone Number
1.800.245.8282
Web Address
kirkmangroup.com
Pharmacist Counseling Corner

L-Carnosine 200 mg by Kirkman: Common Questions

Does L-Carnosine 200 mg by Kirkman interact with any medications?
Yes. Based on its ingredients, L-Carnosine 200 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnosine 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Not based on the data available. There isn't enough safety information about L-carnosine in pregnancy or while nursing, so the facts advise against it. Talk with your doctor or pharmacist for personalized guidance if you're in either situation.
Does L-carnosine actually work for memory or brain aging?
We don't have enough reliable evidence to say. For age-related cognitive decline and Alzheimer disease, the research isn't solid enough yet. For autism spectrum disorder, early evidence suggests it probably isn't effective. If you're considering it for a specific reason, ask your doctor what the current science really shows.
What side effects might I notice?
Most people tolerate it well in short-term use, but some have reported decreased appetite, dry mouth, weight changes, foot or joint pain, and rarely, pneumonia. Stop and talk with your pharmacist if anything concerns you.
Is this safe to take long-term?
We don't have enough data to know. Short-term studies show it's generally well tolerated, but long-term safety is unclear. If you're thinking about taking it regularly for months or years, check with your doctor or pharmacist first.
What exactly is L-carnosine?
It's a compound your body makes naturally from two amino acids. This supplement version is taken by mouth and studied for a range of uses, though evidence for most of them is still developing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Carnosine 200 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnosine 200 mg label
Go deeper

The Full Monographs Behind L-Carnosine 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Carnosine

Interacts with 86 drugs

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is sold as an anti-aging and performance supp...

Read the full Carnosine monograph →
Sources

Sources & How We Checked

L-Carnosine 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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