L-Citrulline Ingredients & Drug Interactions
by NutraKey
What is this page for?
First and foremost: checking L-Citrulline against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Citrulline is a dietary supplement by NutraKey with 1 active ingredient. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Citrulline Malate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Citrulline by NutraKey
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Citrulline by NutraKey — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of L-Citrulline by NutraKey
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — L-citrulline.
- The most serious interaction on file is rated Moderate.
- For scale: 178 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Citrulline, straight from the product label.
| Brand | NutraKey |
|---|---|
| Barcode (UPC) | 456352932740 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 287394 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Citrulline by NutraKey, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Citrulline Malate | 1500 mg | -- |
Other ingredients: Gelatin, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
L-Citrulline 1500mg Boost nitric oxide Increase muscle pump Enhance nitric oxide production L-Citrulline is an amino acid that supports a stable increase of nitric oxide (NO) production. Nitric oxide is responsible for dilating blood vessels, which transport fresh nutrients and oxygen to working muscles through increased blood flow. Muscle performance & detox Lactic acid and ammonia buildup are toxic byproducts of intense exercise which decrease performance. L-Citrulline is an essential intermediary in the urea cycle, a process that rids the body of ammonia. L-Citrulline may also support lactic acid elimination through increased blood flow.
L-Citrulline 1500 mg L-Citrulline Malate
Suggested/Recommended/Usage/Directions
For best results: Combine with Nutrakey's L-Arginine to further support nitric oxide production.
Recommended use: Take 1 serving (2 capsules) with water or your favorite beverage 1-2 times daily or as directed by your physician. For maximum benefit, take 2-4 capsules 30 minutes before workout and 2-4 capsules after workout.
Brand IP Statement(s)
NutraKey Health for every lifestyle
Formulation
Muscle performance Increase nitric oxide Muscle detox Boost nitric oxide Increase blood circulation Support recovery
Non GMO Gluten free Dye free BPA free Parabens free
FDA Statement of Identity
Dietary Supplement
General Statements
Follow us for free giveaways nutrakeyhealth.com
Packaging is BPA (Bisphenol A) free.
Precautions
Warning: Pregnant or lactating women, diabetics, hypoglycemics, are people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.
Do not use if seal is broken. Do not use if packaging has been tampered with.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Citrulline by NutraKey label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Citrulline by NutraKey
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
L-Citrulline Malate
Interacts with178 drugs
L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...
L-Citrulline Malate monograph & interactionsOther (inactive) ingredients: Gelatin, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
L-Citrulline by NutraKey Drug Interactions
L-Citrulline contains a single active ingredient, and it has known interactions with 178 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against L-Citrulline?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Citrulline interact with 178 drugs. Click any drug to see the details.
1 of the 1 ingredient in L-Citrulline interact with drugs. Each result below shows which ingredient is responsible. L-Citrulline Malate
MoexiprilUnivasc
How Moexipril interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Moexipril interactionMoxonidinePhysiotens
How Moxonidine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Moxonidine interactionNadololCorgard, Nadolol
How Nadolol interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nadolol interactionNebivololBystolic, Nebilet
How Nebivolol interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nebivolol interactionNebivolol Hydrochloride, ValsartanByvalson
How Nebivolol Hydrochloride, Valsartan interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nebivolol Hydrochloride, Valsartan interactionNicardipineCardene, Cardene IV, Cardene SR
How Nicardipine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nicardipine interactionNifedipineAdalat, Adalat CC, Adalat LA, Adalat PA, Adalat Retard, Adalat XL +15 more
How Nifedipine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nifedipine interactionNimodipineNimotop, Nymalize
How Nimodipine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nimodipine interactionNisoldipineSular
How Nisoldipine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nisoldipine interactionNitroprussideNitropress
How Nitroprusside interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Nitroprusside interactionOlmesartan MedoxomilBenicar, Olmesartan Medoxomil
How Olmesartan Medoxomil interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Olmesartan Medoxomil interactionOxprenololSlow Trasicor, Trasicor
How Oxprenolol interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Oxprenolol interactionPargylineEutonyl
How Pargyline interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Pargyline interactionPenbutolol SulfateLevatol
How Penbutolol Sulfate interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Penbutolol Sulfate interactionPerindopril Arginine, AmlodipinePrestalia
How Perindopril Arginine, Amlodipine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Perindopril Arginine, Amlodipine interactionPerindopril ErbumineAceon
How Perindopril Erbumine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Perindopril Erbumine interactionPhenoxybenzamineDibenzyline
How Phenoxybenzamine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Phenoxybenzamine interactionPindololPindol, Visken
How Pindolol interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Pindolol interactionPolythiazideRenese
How Polythiazide interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Polythiazide interactionPolythiazide, PrazosinMinizide
How Polythiazide, Prazosin interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Polythiazide, Prazosin interactionPolythiazide, ReserpineRenese R
How Polythiazide, Reserpine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Polythiazide, Reserpine interactionPrazosinMinipress, Prazin, Prazo
How Prazosin interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Prazosin interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Propranolol Hydrochloride interactionQuinaprilAccupril, Accupro
How Quinapril interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Quinapril interactionQuinethazoneHydromox
How Quinethazone interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Quinethazone interactionQuinethazone, ReserpineHydromox R
How Quinethazone, Reserpine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Quinethazone, Reserpine interactionRamiprilAltace
How Ramipril interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Ramipril interactionRescinnamineModeril
How Rescinnamine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Rescinnamine interactionReserpineSandril, Serpasil
How Reserpine interacts with L-Citrulline — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline MalateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Malate + Reserpine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Citrulline with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Citrulline Malate
Antihypertensive Drugs
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.
Phosphodiesterase-5 Inhibitors
Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.
Brand information
Manufacturer and brand details for L-Citrulline, from the product label.
NutraKey
See all NutraKey products- Name
- Nutrakey
- Street Address
- 975 Bennett Drive
- City
- Longwood
- State
- FL
- ZipCode
- 32750
- Web Address
- Nutrakeyhealth.com
L-Citrulline by NutraKey: Common Questions
Does L-Citrulline by NutraKey interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Citrulline is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Citrulline’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Citrulline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
L-citrulline 8 references
- Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
- Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
- Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
- Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
- Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
- Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
- Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
- Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC