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Dietary supplement

L-Tyrosine 500 mg Ingredients & Drug Interactions

by Evlution Nutrition

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Tyrosine 500 mg is a dietary supplement by Evlution Nutrition with 1 active ingredient. Its ingredients are commonly taken for mental focus and alertness, coping with stress, fatigue and sleep loss.Based on those ingredients, 21 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Tyrosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Tyrosine 500 mg by Evlution Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-tyrosine, an amino acid your body uses to make neurotransmitters and thyroid hormones. The capsule also contains inactive ingredients—cellulose, dicalcium phosphate, stearate, and silicon dioxide—which are fillers and binders that hold it together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Neurotransmitter support and stress management.
  • We looked for evidence on: Stress, Fatigue, Sleep deprivation, Cognitive function, Athletic performance, Attention deficit-hyperactivity disorder (ADHD) — and 4 related terms.
  • The strongest evidence on file: Tyrosine is rated "Possibly Effective" for Cognitive function (Natural Medicines).
  • Also on file: Tyrosine is rated "Possibly Effective" for Memory.
  • Also on file: Tyrosine is rated "Possibly Ineffective" for Athletic performance.

The evidence here is mixed. L-tyrosine is effective for phenylketonuria (PKU), a rare genetic condition where the body can't process a related amino acid.

For cognitive function and memory, the evidence suggests it's possibly effective, though the research isn't definitive. For athletic performance, the evidence suggests it's possibly ineffective.

For alcohol use disorder and dementia, we don't yet have enough reliable evidence to say either way.

The evidence, ingredient by ingredient Tyrosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tyrosine is generally well tolerated in healthy adults, but we don't have thorough safety data on regular supplemental use, so talk with a healthcare provider before you start taking it regularly. The most common side effects are fatigue, headache, heartburn, and nausea.

Higher doses can bring on more headache and fatigue. There isn't enough safety data during breastfeeding, so caution is advised if you're nursing—talk to your doctor or pharmacist before using it.

Side effects, ingredient by ingredient Tyrosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tyrosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 21 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take levodopa or any thyroid hormone medication (such as levothyroxine). Both interactions are Moderate in severity.

Levodopa may become less effective if you take tyrosine too close to it. Thyroid hormones may work too well or cause levels to climb too high.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-tyrosine might help with focus or memory in some people, but it's not a sure thing. If you take levodopa for Parkinson's or any thyroid medication, you need to check with us or your doctor first.

For healthy adults, it's generally well tolerated, though some people do experience nausea or headaches. Talk to your pharmacist before you start—especially if you're pregnant, breastfeeding, or on regular medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Tyrosine 500 mg, straight from the product label.

Brand Evlution Nutrition
Barcode (UPC) 818901028180
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326402
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Tyrosine 500 mg by Evlution Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
818901028180
IngredientAmount% DV
L-Tyrosine500 mg--

Other ingredients: Cellulose, Dicalcium Phosphate, Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Tyrosine key product features: 500 mg free-form L-Tyrosine

Formulation

Neurotransmitter support Stress management

Vegan/Non-GMO

Vegan/Non-GMO

This product is made in the USA, has been distributed and manufactured by a (GMP) registered facility and contains ingredients of domestic and international origin.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule daily, preferably with a meal or as recommended by a physician.

Precautions

Warning: Not for use by those under the age of 18. Keep out of reach of children and pets.

Do not use if you are nursing or pregnant.

Storage

Store product at room temperature. Do not expose to excessive heat or moisture.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Instagram Facebook Twitter @EVLSports #EVL

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the USA

See for yourself

L-Tyrosine 500 mg by Evlution Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Tyrosine 500 mg by Evlution Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

L-Tyrosine

Interacts with
21 drugs
500 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

Other (inactive) ingredients: Cellulose, Dicalcium Phosphate, Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Tyrosine 500 mg by Evlution Nutrition Drug Interactions

Want to check YOUR meds against L-Tyrosine 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
21Drugs
21 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Tyrosine 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for L-Tyrosine 500 mg, from the product label.

Evlution Nutrition

See all Evlution Nutrition products
Name
Evlution Nutrition
Street Address
1560 Sawgrass Corporate Parkway, 4th Floor
City
Sunrise
State
Florida
ZipCode
33323
Phone Number
1(855)385-2300
Web Address
Evlnutrition.com
Pharmacist Counseling Corner

L-Tyrosine 500 mg by Evlution Nutrition: Common Questions

Does L-Tyrosine 500 mg by Evlution Nutrition interact with any medications?
Yes. Based on its ingredients, L-Tyrosine 500 mg has a known interaction with 21 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Tyrosine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will L-tyrosine actually help me think more clearly?
The evidence suggests it's possibly effective for cognitive function and memory, but the research isn't conclusive. It works for a rare genetic condition called PKU, but for everyday brain fog or focus, results aren't guaranteed.
What are the most common side effects?
Fatigue, headache, heartburn, and nausea are the most commonly reported. Most people tolerate it well, but if these pop up, they're mild and can often be managed by lowering the dose or stopping.
Is it safe to take L-tyrosine while breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist for personalized advice before using it while nursing.
Can I take this if I'm pregnant?
The safety data on file doesn't tell us one way or the other. Chat with your doctor or pharmacist to figure out what's right for you and your baby.
Does this product have any fillers?
Yes—it contains cellulose, dicalcium phosphate, stearate, and silicon dioxide as inactive ingredients. These are standard binders and fillers that help hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Tyrosine 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Tyrosine 500 mg label
Go deeper

The Full Monographs Behind L-Tyrosine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Tyrosine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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