Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Lady's Mantle Ingredients & Drug Interactions

by Hawaii Pharm

Lady's Mantle label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lady's Mantle against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Lady's Mantle is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for menstrual and women's health complaints, diarrhea and digestive upset, wound healing (topical).Based on those ingredients, 198 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Lady's Mantle Herb Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lady's Mantle by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Lady's Mantle by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Lady's Mantle by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains one active ingredient: Lady's Mantle Herb Extract, Dry. Lady's Mantle is a plant extract traditionally used for various purposes, though the evidence supporting its effectiveness is limited.

The product also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Alchemilla product and its label doesn't state a use — see Alchemilla's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Lady's Mantle isn't established in our data. The product is sometimes used for postoperative sore throat and canker sores, but we hold insufficient reliable evidence to rate how well it works for either condition.

If you're considering it for one of these uses, it's worth discussing with your doctor or dentist whether it's the right choice for you.

The evidence, ingredient by ingredient Alchemilla

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lady's Mantle is generally considered low-risk in small amounts, but human safety data are limited — we simply don't have enough studies to be certain about long-term use. The safety data advise against using this product during pregnancy or while breastfeeding.

If you're pregnant, nursing, or planning either, talk with your pharmacist or doctor before taking it.

Side effects, ingredient by ingredient Alchemilla

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alchemilla.
  • The most serious interaction on file is rated Minor.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any topical medications you use before starting this product, as a Minor interaction has been documented with topical drugs. Because the documented interaction involved mouth irritation from topical application, the relevance to oral use is unclear, but it's worth verifying with your pharmacist or doctor.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and some safety-information gaps remain.

Lady's Mantle may be worth considering if you're looking for a traditional herbal remedy, but the evidence for what it actually does is thin. The main caution is a documented interaction with topical drugs involving mouth irritation.

If you take any medications — especially topical ones — or are pregnant or breastfeeding, check with us first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lady's Mantle, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253631572
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 301386
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lady's Mantle by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253631572
IngredientAmount% DV
Lady's Mantle Herb Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Alchemilla vulgaris

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lady's Mantle by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lady's Mantle label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lady's Mantle by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Lady's Mantle Herb Extract, Dry

Interacts with
198 drugs
983 mg per serving Form: Alchemilla vulgaris Herb Extract, Dry

Alchemilla (lady's mantle) is a European herb traditionally used for digestive complaints, women's health issues, and as an astringent for skin and wo...

Lady's Mantle Herb Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lady's Mantle by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Lady's Mantle?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
198 Minor

Ingredients driving the most interactions

Lady's Mantle Herb Extract, Dry 198

Individual Drug Interactions

The ingredients in Lady's Mantle interact with 198 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lady's Mantle interact with drugs. Each result below shows which ingredient is responsible. Lady's Mantle Herb Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Lady's Mantle with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lady's Mantle Herb Extract, Dry1 drug type · 198 drugs

Topical Drugs

While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topical Alchemilla vulgaris in Glycerine," published in Clinical Drug Investigation (https://pubmed.ncbi.nlm.nih.gov/17163290/), found that local mouth irritation occurred after applying a commercial product containing 3% alchemilla extract and glycerol (Aphtarine, Laboratoires Biosphere). Aphtarine was non-irritating in 68.2% of cases within 2-3 days, in 18.8% of cases within 4-7 days, and in 13.6% of cases with moderate irritation. Theoretically, combining Alchemilla with other potentially irritating topical products could increase the risk of local irritation and discomfort. The drug in this drug interaction monograph is available in a topical dosage form. There is no interaction expected from the oral dosage form of the drug.

Likelihood Possible Evidence D
Lady's Mantle Herb Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lady's Mantle, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Lady's Mantle by Hawaii Pharm: Common Questions

Does Lady's Mantle by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Lady's Mantle has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lady's Mantle contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Lady's Mantle if I'm pregnant?
The safety data advise against it. There isn't enough information to know whether it's safe during pregnancy, so it's best avoided. Talk with your doctor or pharmacist if you're pregnant or planning to become pregnant.
Can I take Lady's Mantle while breastfeeding?
The safety data advise against it. There isn't enough information to know whether it's safe while breastfeeding, so it's best avoided. Speak with your pharmacist or doctor if you're nursing or plan to.
Does Lady's Mantle actually work for sore throat or canker sores?
We don't have enough reliable evidence to say. Both uses are listed in traditional herbalism, but the science backing them up isn't solid in our data. Your doctor or dentist can help you decide if it's worth trying.
What's in this liquid besides the herb extract?
The product contains alcohol, water, and glycerin. These are inactive ingredients — they help deliver the extract but aren't the active part.
Is Lady's Mantle safe to use long-term?
While it's generally considered low-risk in small amounts, human safety data are limited, so we don't have solid information about long-term use. If you're thinking of taking it regularly, check in with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lady's Mantle is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lady's Mantle label
Go deeper

The Full Monographs Behind Lady's Mantle’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Alchemilla

Interacts with 198 drugs

Alchemilla (lady's mantle) is a European herb traditionally used for digestive complaints, women's health issues, and as an astringent for skin and wounds. Solid human research is very limit...

Read the full Alchemilla monograph →
Sources

Sources & How We Checked

Lady's Mantle's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alchemilla 1 reference
  1. Herbs at a Glance — NIH NCCIH Source

See these in context on the Alchemilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team