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Dietary supplement

Lemongrass Ingredients & Drug Interactions

by Zongle Therapeutics

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Lemongrass is a dietary supplement by Zongle Therapeutics with 1 active ingredient. Its ingredients are commonly taken for digestive upset, anxiety and stress, antimicrobial/antifungal.Based on those ingredients, 708 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lemongrass. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Lemongrass by Zongle Therapeutics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lemongrass. The liquid form includes steam-distilled lemongrass oil as an inactive ingredient (the vehicle that carries the active lemongrass).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lemongrass's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy digestion and skin health.
  • We looked for evidence on: Nausea and vomiting, Abdominal pain, indigestion, gastrointestinal comfort.
  • The closest evidence on file: Lemongrass is rated "Insufficient Reliable Evidence To Rate" for Nausea and vomiting (Natural Medicines).
  • Also on file: Lemongrass is rated "Insufficient Reliable Evidence To Rate" for Abdominal pain.

The evidence we hold does not establish that lemongrass is effective for any of the conditions it's marketed toward—headache, common cold, cough, diabetes, epilepsy, or fatigue. All six uses are listed as having insufficient reliable evidence to rate.

The evidence, ingredient by ingredient Lemongrass

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lemongrass is likely safe in food amounts, but this product is a concentrated liquid extract, and concentrated forms have less safety data behind them. Medicinal or concentrated amounts should be avoided due to limited safety information and traditional safety concerns.

Lemongrass is rated likely unsafe in pregnancy—the safety data advises against use during pregnancy. We hold no data on safety during breastfeeding, so talk with your doctor or pharmacist for personalized advice if you're nursing.

Side effects, ingredient by ingredient Lemongrass

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lemongrass.
  • The most serious interaction on file is rated Moderate.
  • For scale: 709 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check your medications against these three drug types with your pharmacist: pentobarbital and other sedatives (risk of increased drowsiness and side effects), CYP3A4 substrates like certain cholesterol and blood pressure medications (risk of higher levels and side effects), and glucuronidated drugs (risk of lower effectiveness). The interaction data we hold covers a very broad range of medications, so even if your drug isn't in one of these categories, it's worth confirming.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Because we don't have reliable evidence that lemongrass works for its marketed uses, and because it interacts with a very large number of medications through multiple pathways, this isn't a straightforward choice. If you're considering it, check your medications first using the tool on this page, and talk it over with your doctor or pharmacist—especially if you take any sedatives, heart drugs, blood pressure medications, or other prescription drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lemongrass, straight from the product label.

Brand Zongle Therapeutics
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 277112
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lemongrass by Zongle Therapeutics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
250
IngredientAmount% DV
Lemongrass60 mg--

Other ingredients: Lemongrass Oil, Steam-Distilled

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic, topical or internal use.

For internal use dilute one drop in 4 fl. oz. of liquid. Dilute for kids or sensitive skin.

Formulation

Supports healthy digestion Provides a soothing massage Purifying and toning to the skin Refreshing and deodorizing

100% pure Therapeutic Grade

Origin: India Bottled in USA

Artificial ingredients free GMO free Gluten free Preservatives free Paraben free

Vegan

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If you are pregnant, nursing, or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas.

Formula

Cymbopogon flexuosus

Adds subtle citrus flavor to cuisine.

FDA Statement of Identity

Essential Oil Supplement

See for yourself

Lemongrass by Zongle Therapeutics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lemongrass by Zongle Therapeutics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container250 Amounts shown are per serving.

Lemongrass

Interacts with
708 drugs
60 mg per serving

Lemongrass is a fragrant tropical grass widely used as a cooking herb, a tea, and an aromatherapy oil. It is generally considered safe in the small am...

Lemongrass monograph & interactions

Other (inactive) ingredients: Lemongrass Oil, Steam-Distilled. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lemongrass by Zongle Therapeutics Drug Interactions

Want to check YOUR meds against Lemongrass?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
708Drugs
708 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Lemongrass with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lemongrass3 drug types · 708 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Animal research shows that lemongrass and its constituent citral inhibit CYP3A4.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, lemongrass might increase the clearance and decrease the levels of glucuronidated drugs.
Animal research shows that lemongrass and its constituent citral induce uridine diphosphoglucuronosyl transferase (UGT), the major phase 2 enzyme that is responsible for glucuronidation.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, lemongrass might increase the effects and adverse effects of pentobarbital.
Animal research shows that high doses of lemongrass essential oil increases sleep time and decreases time to fall asleep in animals administered pentobarbital.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Lemongrass, from the product label.

Zongle Therapeutics

See all Zongle Therapeutics products
Name
Zongle Therapeutics LLC
Web Address
www.zongletherapeutics.com
Pharmacist Counseling Corner

Lemongrass by Zongle Therapeutics: Common Questions

Does Lemongrass by Zongle Therapeutics interact with any medications?
Yes. Based on its ingredients, Lemongrass has a known interaction with 708 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lemongrass contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lemongrass safe to take while pregnant?
No. Lemongrass is rated likely unsafe in pregnancy, so the safety data advises against use if you're pregnant or planning to become pregnant. Talk with your doctor before taking any supplement during pregnancy.
Does this lemongrass liquid actually work for colds or headaches?
We don't have reliable evidence backing lemongrass for either of those uses. The data rates both as having insufficient reliable evidence—meaning the science isn't there yet to say whether it helps.
Why does the label say to avoid medicinal amounts?
Concentrated forms like this liquid extract have less safety data than lemongrass in everyday food amounts. Medicinal doses come with traditional safety concerns and not enough modern research to be sure they're safe, so the advice is to stick to occasional food use rather than therapeutic amounts.
What's the difference between this liquid and lemongrass tea?
This is a concentrated extract, which is much more potent than brewed tea. Food amounts of lemongrass are likely safe, but concentrated forms have weaker safety data and carry the interaction risks we've covered.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lemongrass is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lemongrass label
Sources

Sources & How We Checked

Lemongrass's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemongrass 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Li CC, Yu HF, Chang CH, Liu YT, Yao HT. Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats. J Food Drug Anal 2018;26(1):432-8. PubMed

See these in context on the Lemongrass monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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