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Dietary supplement

Lion's Mane Drops Ingredients & Drug Interactions

by Ron Teeguarden's Dragon Herbs

Lion's Mane Drops label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lion's Mane Drops against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lion's Mane Drops is a dietary supplement by Ron Teeguarden's Dragon Herbs with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Fruiting Body Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lion's Mane Drops by Ron Teeguarden's Dragon Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Lion's Mane Drops by Ron Teeguarden's Dragon Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lion's Mane Drops by Ron Teeguarden's Dragon Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Lion's Mane Drops is a single-ingredient supplement: lion's mane mushroom fruiting body extract in a liquid base of water and grain alcohol. The extract is the concentrated active form of the mushroom, designed for easy dosing.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: brain tonic supporting cognitive function.
  • We looked for evidence on: Memory, Cognitive function, Cognitive impairment, Dementia, Alzheimer disease, Parkinson disease — and 3 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Cognitive impairment, Dementia, Memory, and more.

The evidence for lion's mane mushroom isn't established in the data we hold. The supplement has been studied for Alzheimer disease, anxiety, athletic performance, cancer, and both general cognitive function and cognitive impairment—but in each case, the data shows insufficient reliable evidence to rate whether it works.

You're essentially trying something with potential but without solid proof behind it yet.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, lion's mane mushroom is generally well tolerated as a food. In supplement form, the long-term safety hasn't been well studied.

The most common side effects are mild: gastrointestinal discomfort, nausea, and skin rash. There isn't enough safety data to recommend this during pregnancy or while breastfeeding.

If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use anticoagulant or antiplatelet drugs (blood thinners), antidiabetes medications, or immunosuppressants. The extract may increase bleeding risk, lower blood sugar further, or reduce immune-suppressing medication effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Lion's Mane Drops might interest someone looking to support brain health or cognition, though the evidence isn't solid yet. If you take blood thinners, diabetes medication, or immunosuppressants, you'll want to check this with your doctor or pharmacist first—the interactions are real and Moderate in severity.

Talk it over with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lion's Mane Drops, straight from the product label.

Brand Ron Teeguarden's Dragon Herbs
Barcode (UPC) 679372000286
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279027
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lion's Mane Drops by Ron Teeguarden's Dragon Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.25 mL
Maximum serving Sizes:
9 mL
Servings per container
27
UPC/BARCODE
679372000286
IngredientAmount% DV
Lion's Mane Fruiting Body Extract2.25 mL--

Other ingredients: Water, Grain Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Lion's Mane is a mushroom that has emerged from East Asian Buddhist herbal tradition to become an extremely valued and respected modern brain tonic. This mushroom fruiting body contains nerve growth factor and is believed to support brain plasticity and brain health.

Formulation

Dragon Herbs uses advanced extraction technology to produce this rich, full-spectrum, hydro-ethanolic extract that contains all of Lion's Mane's active constituents in just the right balance.

Super potency extract

Suggested/Recommended/Usage/Directions

You may consume this delicious tonic every day of your life.

Directions: 3-12 squirts per day as desired or as directed by a health practitioner. Shake well before use. A squirt is a single full squeeze of the rubber bulb.

General Statements

Dragon Drops

Seals/Symbols

Di Tao Certified Authentic Source

FDA Statement of Identity

Dietary Supplement

Precautions

Keep out of the reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lion's Mane Drops by Ron Teeguarden's Dragon Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lion's Mane Drops label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lion's Mane Drops by Ron Teeguarden's Dragon Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2.25 mL Dosage formLiquid Servings per container27 Amounts shown are per serving.

Lion's Mane Fruiting Body Extract

Interacts with
327 drugs
2.25 mL per serving

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Fruiting Body Extract monograph & interactions

Other (inactive) ingredients: Water, Grain Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lion's Mane Drops by Ron Teeguarden's Dragon Herbs Drug Interactions

Want to check YOUR meds against Lion's Mane Drops?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane Fruiting Body Extract 327

Individual Drug Interactions

The ingredients in Lion's Mane Drops interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lion's Mane Drops interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane Fruiting Body Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lion's Mane Drops with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Fruiting Body Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Fruiting Body Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lion's Mane Drops, from the product label.

Ron Teeguarden's Dragon Herbs

See all Ron Teeguarden's Dragon Herbs products
Name
Ron Teeguarden's Dragon Herbs
Street Address
P.O. Box 361459
City
Los Angeles
State
CA
ZipCode
90036
Phone Number
(888) 558-6642
Web Address
www.dragonherbs.com
Pharmacist Counseling Corner

Lion's Mane Drops by Ron Teeguarden's Dragon Herbs: Common Questions

Does Lion's Mane Drops by Ron Teeguarden's Dragon Herbs interact with any medications?
Yes. Based on its ingredients, Lion's Mane Drops has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lion's Mane Drops contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's lion's mane mushroom supposed to do?
Lion's mane has been studied for memory, cognition, Alzheimer disease, anxiety, and cancer, but the data we have shows insufficient evidence to say whether it actually works for any of those. It's a traditional ingredient with potential, but solid proof isn't there yet.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data to recommend lion's mane during pregnancy or while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're in either situation.
What side effects might I notice?
Most people tolerate it well, but some experience gastrointestinal discomfort, nausea, or a skin rash. These are generally mild, but if they bother you, stop and let your pharmacist know.
Is this safe long-term?
Lion's mane is generally well tolerated as a food, but the long-term safety of the supplement form hasn't been well studied. We don't have solid data on what happens with months or years of use.
Why does this product interact with so many medications?
It doesn't interact with all 327 medications directly—that's the total count across all the drug types affected. You'll only have a real concern if you take blood thinners, diabetes meds, or immunosuppressants. The checker below will tell you exactly what applies to your prescriptions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lion's Mane Drops is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lion's Mane Drops label
Go deeper

The Full Monographs Behind Lion's Mane Drops’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Lion's Mane Drops's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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