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Dietary supplement

Liposomal Sulforaphane Berry Flavor Ingredients & Drug Interactions

by DaVinci Laboratories

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Liposomal Sulforaphane Berry Flavor is a dietary supplement by DaVinci Laboratories with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BroccoPhane. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “BroccoPhane” is listed as a grouped ingredient — the label gives one combined amount (93.75 mg) without saying how much of each component you get.

This product contains one active ingredient: sulforaphane, a compound extracted from broccoli sprouts. Sulforaphane is a plant chemical (phytonutrient) studied for potential effects on cellular health and specific conditions.

The liquid formula includes several inactive ingredients — glycerin, water, oils, lecithin, bilberry extract, xanthan gum, and other excipients that create the liposomal delivery system and berry flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sulforaphane's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sulforaphane for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Natural Medicines).

Sulforaphane shows possibly effective evidence for prostate cancer. For other conditions — including Helicobacter pylori (a stomach bacteria), allergic rhinitis (hay fever), asthma, and cancer broadly — the evidence is either insufficient to rate or points toward ineffectiveness.

The data we hold doesn't establish it as effective for those other uses.

The evidence, ingredient by ingredient Broccoli Sulforaphane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, sulforaphane from food is well tolerated. Concentrated supplements like this one are less studied long-term.

The most common side effects reported are bowel discomfort, heartburn, stomach upset, and vomiting. Individual cases have noted headache, insomnia, irritability, and increased weight gain; two cases of seizure have been reported in males with autism, though the direct cause remains unclear.

Concentrated sulforaphane supplements haven't been proven safe in pregnancy, so the data advises against them — stick to normal food amounts instead. There isn't enough information on supplement-level doses during breastfeeding; talk with your doctor or pharmacist about whether to use it or prefer dietary sources.

The product label rates overall pregnancy and lactation safety as "Likely Safe," but that conflicts with the caution noted for concentrated supplements; your own healthcare provider can help you weigh that for your situation.

Side effects, ingredient by ingredient Broccoli Sulforaphane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sulforaphane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 723 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any CYP3A4 substrates, CYP1A2 substrates, or CYP2E1 substrates — medications processed through these liver pathways. All three interact at Moderate severity.

If you're unsure whether your drugs are affected, use the medication checker on this page or ask your pharmacist directly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may interest you if you're looking into sulforaphane for prostate health and have checked your medications for interactions with liver-enzyme substrates. If you take any prescription or over-the-counter drugs — especially those processed by your liver — clear this with your doctor or pharmacist first.

Pregnant women should avoid concentrated supplements and stick to broccoli in food. Anyone with a history of seizure should discuss it with their provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal Sulforaphane Berry Flavor, straight from the product label.

Brand DaVinci Laboratories
Barcode (UPC) 026664014610
Net contents 2 Fluid Ounce(s); 60 Milliliter(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303979
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
026664014610
IngredientAmount% DV
Total Carbohydrates1 Gram(s)--
Sulforaphane375 mcg--
BroccoPhane93.75 mg--

Other ingredients: Glycerin, Water, Oleic Acid Polyglyceride, Natural Flavors, Sunflower Lecithin, Sunflower Oil, Bilberry extract, Xanthan Gum, Potassium Citrate, Mixed Tocopherols, Rosmarinic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 mL in AM and PM, or as directed by your healthcare practitioner. Shake well before each use.

Formulation

Color, flavor and sweetness of this product may vary due to variations of natural ingredients.

Detoxification and Nrf2 support

Vegetarian

Gluten free Soy free Dairy free

Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Caution: Do not put glass dropper directly in mouth.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

Storage

Store in a cool, dry place.

Best if used within 60 days of opening.

Brand IP Statement(s)

BroccoPhane is a registered trademark of Cyvex Nutrition, Inc.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

BroccoPhane

Interacts with
187 drugs
93.75 mg per serving Form: Broccoli, Powder

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

BroccoPhane monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Oleic Acid Polyglyceride, Natural Flavors, Sunflower Lecithin, Sunflower Oil, Bilberry extract, Xanthan Gum, Potassium Citrate, Mixed Tocopherols, Rosmarinic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories Drug Interactions

Want to check YOUR meds against Liposomal Sulforaphane Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
723Drugs
723 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Liposomal Sulforaphane Berry Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BroccoPhane2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Liposomal Sulforaphane Berry Flavor, from the product label.

DaVinci Laboratories

See all DaVinci Laboratories products
Name
DaVinci Laboratories a division of FoodScience LLC
Street Address
929 Harvest Lane
City
Williston
State
VT
ZipCode
05495
Phone Number
1-800-325-1776
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories: Common Questions

Does Liposomal Sulforaphane Berry Flavor by DaVinci Laboratories interact with any medications?
Yes. Based on its ingredients, Liposomal Sulforaphane Berry Flavor has a known interaction with 723 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liposomal Sulforaphane Berry Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is sulforaphane and where does it come from?
Sulforaphane is a plant compound (phytonutrient) found naturally in broccoli sprouts and other cruciferous vegetables. This product delivers it in a concentrated liposomal liquid form designed for better absorption.
Does sulforaphane actually work for cancer or other conditions?
For prostate cancer, the evidence rates as possibly effective. For Helicobacter pylori, allergic rhinitis (hay fever), asthma, and cancer broadly, the evidence we have is either too weak to rate or suggests it may not be effective. Talk with your doctor about whether it fits your specific situation.
What side effects should I watch for?
The most common are bowel discomfort, heartburn, stomach upset, and vomiting. Headache, insomnia, irritability, and weight gain have been reported in clinical studies. In rare cases, seizures have occurred in males with autism; if you or a family member has a seizure history, mention this to your doctor before starting.
Is it safe to take while pregnant or breastfeeding?
Concentrated sulforaphane supplements haven't been proven safe in pregnancy — the data advises against them, so stick to normal food amounts if you're pregnant. There isn't enough information on supplement doses while breastfeeding; talk with your doctor or pharmacist about the safest choice for you.
Does this interact with my medications?
Sulforaphane may affect how your liver processes over 700 medications, particularly those handled by three enzyme systems (CYP3A4, CYP1A2, and CYP2E1). Use the medication checker on this page or ask your pharmacist to review your exact drugs before you start.
What are the inactive ingredients?
The product contains glycerin, water, oils, sunflower lecithin, bilberry extract, xanthan gum, and other excipients that make up the liposomal delivery system and berry flavor. If you have allergies or sensitivities to any of these, check the full list before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal Sulforaphane Berry Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal Sulforaphane Berry Flavor label
Sources

Sources & How We Checked

Liposomal Sulforaphane Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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