Lutein 20 mg Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking Lutein 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lutein 20 mg is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Lutein 20 mg by DC
Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein 20 mg by DC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Lutein 20 mg by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: zeaxanthin, a carotenoid (a natural plant pigment) at 20 mg per capsule. Zeaxanthin is the same compound found in leafy greens and other colorful foods — here it's concentrated into a single dose.
The other ingredients are inactive (safflower oil, gelatin, vegetable glycerin, beeswax, and mixed tocopherols), which help deliver and preserve the zeaxanthin.
Does it work?
Moderate evidence
Zeaxanthin is possibly effective for age-related macular degeneration (AMD), the leading cause of vision loss in older adults. For other conditions — age-related cognitive decline, Alzheimer disease, asthma, breast cancer, and bronchopulmonary dysplasia — the evidence in our data is insufficient to rate how well it works.
That doesn't mean it doesn't work; it means we don't yet have reliable data to say either way.
How safe is it?
Some data gaps
Zeaxanthin is generally well tolerated at typical supplement doses. For pregnancy, the safety data on concentrated supplements isn't well studied — food sources are fine, but talk with your doctor or pharmacist about whether a supplement makes sense for you.
For breastfeeding, there's not enough data on concentrated supplements, so the same caution applies; food sources are considered safe.
Meds to double-check
Moderate interaction found
If you take antidiabetes drugs (insulin, metformin, or any other blood sugar medication), this product may increase the risk of low blood sugar. Check your exact medications with the tool on this page before adding this supplement, and let your doctor or pharmacist know you're considering it.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
If you have age-related macular degeneration or want to support eye health, this supplement may be worth discussing with your eye doctor. If you take any blood sugar medication, check with your doctor or pharmacist first — zeaxanthin may lower blood sugar further.
Anyone on antidiabetes drugs, pregnant, or breastfeeding should have that conversation before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lutein 20 mg, straight from the product label.
| Brand | DC |
|---|---|
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 245383 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lutein 20 mg by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Zeaxanthin | 1 mg | -- |
| Lutein | 20 mg | -- |
Other ingredients: Safflower Oil, Gelatin, Vegetable Glycerin, yellow Beeswax, Mixed Tocopherols
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement take 1 softgel daily after a meal.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing do not take this product.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Glute free
Nutritionally supports healthy eye function
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Made in USA
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
Formula
Lutein is one of the most abundant carotenoids found in fruits, vegetables and even plants like marigolds. Lutein has antioxidant properties and is found in the macula of healthy eyes.
GloraGlo Natural carotenoid w/zeaxanthin
FloraGlo Lutein
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is to intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Quali Pure
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Flora Glo is a registered trademark of Kemin Industries, Inc.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lutein 20 mg by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lutein 20 mg by DC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Lutein
No knowninteractions
Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...
Lutein monograph & interactionsOther (inactive) ingredients: Safflower Oil, Gelatin, Vegetable Glycerin, Yellow Beeswax, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.
Lutein 20 mg by DC Drug Interactions
HelloPharmacist Interaction Report
DC's Lutein 20 mg contains zeaxanthin, which has documented interactions with one class of medications.
The most serious concern is with antidiabetes drugs (medications that lower blood sugar), where zeaxanthin may increase the risk of low blood sugar (hypoglycemia) — a Moderate-severity interaction. Animal studies show zeaxanthin can lower blood sugar on its own, though population research hasn't found that dietary zeaxanthin and lutein together reduce the risk of developing type 2 diabetes.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 86 individual medications. If you take any antidiabetes drug — insulin, metformin, sulfonylureas, or any other blood sugar medication — run your exact medications through the interaction checker on this page before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Lutein 20 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Lutein 20 mg interact with 86 drugs. Click any drug to see the details.
0 of the 1 ingredient in Lutein 20 mg interact with drugs. Each result below shows which ingredient is responsible.
Metformin XrGlucophage XR
How Metformin Xr interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Metformin Xr interactionMetformin, LinagliptinJentadueto
How Metformin, Linagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Metformin, Linagliptin interactionMetformin, RosiglitazoneAvandamet
How Metformin, Rosiglitazone interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Metformin, Rosiglitazone interactionMetformin, SitagliptinJanumet, Janumet XR
How Metformin, Sitagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Metformin, Sitagliptin interactionMiglitolGlyset
How Miglitol interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Miglitol interactionMuraglitazarPargluva
How Muraglitazar interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Muraglitazar interactionNateglinideStarlix
How Nateglinide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Nateglinide interactionPioglitazoneActos
How Pioglitazone interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Pioglitazone interactionPramlintideSymlin
How Pramlintide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Pramlintide interactionRepaglinideGlucoNorm, Prandin
How Repaglinide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Repaglinide interactionRosiglitazone MaleateAvandia
How Rosiglitazone Maleate interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Rosiglitazone Maleate interactionSaxagliptinOnglyza
How Saxagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Saxagliptin interactionSaxagliptin, Metformin XrKombiglyze
How Saxagliptin, Metformin Xr interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Saxagliptin, Metformin Xr interactionSemaglutideOzempic, Rybelsus, Wegovy
How Semaglutide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Semaglutide interactionSimvastatin, SitagliptinJuvisync
How Simvastatin, Sitagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Simvastatin, Sitagliptin interactionSitagliptinJanuvia, Zituvio
How Sitagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Sitagliptin interactionSitagliptin, MetforminZituvimet
How Sitagliptin, Metformin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Sitagliptin, Metformin interactionSotagliflozinInpefa
How Sotagliflozin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Sotagliflozin interactionTirzepatideMounjaro, Zepbound
How Tirzepatide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Tirzepatide interactionTobutamideMobenol
How Tobutamide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Tobutamide interactionTolazamideTolinase
How Tolazamide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Tolazamide interactionTolbutamideOrinase
How Tolbutamide interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Tolbutamide interactionTroglitazoneRezulin
How Troglitazone interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Troglitazone interactionVildagliptinGalvus
How Vildagliptin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Vildagliptin interactionPioglitazone, MetforminActoPlus Met
How Pioglitazone, Metformin interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Pioglitazone, Metformin interactionRosiglitazone, GlimepirideAvandaryl
How Rosiglitazone, Glimepiride interacts with Lutein 20 mg — through 1 ingredient. Tap an ingredient for the detail:
ZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Rosiglitazone, Glimepiride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Lutein 20 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brand information
Manufacturer and brand details for Lutein 20 mg, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Rd.
- City
- White House
- State
- TN
- ZipCode
- 37188
Lutein 20 mg by DC: Common Questions
Does Lutein 20 mg by DC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is zeaxanthin?
Does this really help with age-related macular degeneration?
Can I take this if I'm pregnant?
Is it safe while breastfeeding?
What are the inactive ingredients?
Why is blood sugar a concern with this supplement?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lutein 20 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lutein 20 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lutein
Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...
Read the full Lutein monograph → Herb & supplement monographZeaxanthin
Interacts with 86 drugsZeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...
Read the full Zeaxanthin monograph →Sources & How We Checked
Lutein 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Zeaxanthin 4 references
- Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
- Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
- Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
- Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed
Lutein 2 references
- Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
- Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC