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Dietary supplement

Royal Jelly 1000 mg Ingredients & Drug Interactions

by DC

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Royal Jelly 1000 mg is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Royal Jelly 1000 mg by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Royal Jelly” is listed as a grouped ingredient — the label gives one combined amount (2,000 mg) without saying how much of each component you get.

This product contains one active ingredient: royal jelly concentrate at 1000 mg per capsule. Royal jelly is a nutrient-rich secretion produced by honeybees; it's used in supplements for various health purposes.

The capsule itself is made from gelatin, vegetable cellulose, vegetable magnesium stearate, and silica — inactive ingredients that serve as the capsule shell and to ensure even distribution.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: nutrient-rich supplement supporting overall wellness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Royal jelly is possibly effective for menopausal symptoms based on available evidence. For allergic rhinitis (hay fever), physical performance, and diabetes, the evidence suggests it's possibly ineffective.

The evidence for its use in androgenic alopecia (male pattern baldness) isn't strong enough to rate. If you're considering this product for one of these uses, talk with your doctor or pharmacist about whether the evidence supports it for your specific situation.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal jelly is generally well tolerated in most people, but it carries a serious risk if you have a history of asthma or atopy (a tendency toward allergic reactions). In sensitive individuals, it can trigger shortness of breath, eczema, itching, hives, oral allergy syndrome — and rarely, life-threatening reactions like anaphylaxis or severe asthma.

There's also one case report of bloody diarrhea linked to royal jelly that resolved after stopping it. The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe.

If you're pregnant or nursing and interested in royal jelly, talk with your doctor or pharmacist.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on warfarin or another blood thinner — royal jelly may increase bleeding risk. Also flag any antihypertensive drugs (blood pressure medications) you're taking, since royal jelly might lower your blood pressure further.

If you're unsure whether your medications fall into these categories, use the interaction checker below with your specific drug names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Jelly 1000 mg might be worth considering if you're looking for support with menopausal symptoms and you don't have asthma, allergies, or a history of allergic reactions. If you take warfarin or blood pressure medications, check with your doctor or pharmacist before starting — the interaction risk is real.

Anyone with a personal or family history of severe allergies should avoid this product or use it only under medical supervision.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Jelly 1000 mg, straight from the product label.

Brand DC
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 266817
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Jelly 1000 mg by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
IngredientAmount% DV
Royal Jelly concentrate572 mg--
Royal Jelly2000 mg--

Other ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant, nursing, have asthma or related allergies do not take this product.

Caution: If you are pregnant, nursing, have asthma or related allergies do not take this product.

Formulation

FDA Registered Facility (Reg. # 1023013) Mfg. under Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Made in USA

Formula

Royal Jelly ("Bee's Milk") contains protein, minerals, vitamins, amino acids, and other natural factors, including 10-Hydroxy-2-Decenoic Acid (10-HDA).

Assayed to contain 4.8% 10-HDA

General Statements

It is this extraordinary, nutrient rich food that turns the common worker bee into the dynamic Queen Bee, making her a giant among her relatives, giving her enormous strength and extending her life many times over.

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 2 capsules twice daily, preferably with a meal.

See for yourself

Royal Jelly 1000 mg by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Royal Jelly 1000 mg by DC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Royal Jelly

Interacts with
174 drugs
2000 mg per serving Form: 10-Hydroxy-2-decenoic Acid

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly monograph & interactions

Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Jelly 1000 mg by DC Drug Interactions

Want to check YOUR meds against Royal Jelly 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Jelly 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Royal Jelly 1000 mg, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Royal Jelly 1000 mg by DC: Common Questions

Does Royal Jelly 1000 mg by DC interact with any medications?
Yes. Based on its ingredients, Royal Jelly 1000 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Jelly 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is royal jelly safe if I have asthma or allergies?
No — it's not safe for people with asthma or a history of allergic reactions. Royal jelly can trigger serious allergic symptoms in sensitive people, including itching, hives, eczema, shortness of breath, and rarely, life-threatening reactions like anaphylaxis. If this describes you, avoid this product.
Can I take this while I'm pregnant or breastfeeding?
The safety data advises against it because there isn't enough information to know either way. Talk with your doctor or pharmacist about whether royal jelly is right for you during pregnancy or while nursing.
Does royal jelly actually help with hot flashes and other menopausal symptoms?
The evidence suggests it's possibly effective for menopausal symptoms, meaning there's some research support but it's not definitive. Your results may vary, and your doctor can help you decide if it's worth trying as part of your symptom management plan.
What's in the capsule besides royal jelly?
The capsule shell itself is made from gelatin and vegetable cellulose, with vegetable magnesium stearate and silica added to keep everything stable and uniform. These are all inactive ingredients — they don't provide a therapeutic effect, just structure.
Can royal jelly cause side effects in people without allergies?
In most people without a history of allergies or asthma, royal jelly is well tolerated with few side effects. However, there's one case report of bloody diarrhea linked to royal jelly that resolved after stopping it, so uncommon reactions are possible.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Royal Jelly 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Jelly 1000 mg label
Sources

Sources & How We Checked

Royal Jelly 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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