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Dietary supplement

Lutein 40 mg Ingredients & Drug Interactions

by Solgar

Lutein 40 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein 40 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein 40 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lutein 40 mg by Solgar

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein 40 mg by Solgar — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lutein 40 mg by Solgar

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Lutein” is listed as a grouped ingredient — the label gives one combined amount (40 mg) without saying how much of each component you get.

This softgel contains one active ingredient: zeaxanthin, a carotenoid (natural pigment) that concentrates in your eye. The product also includes inactive ingredients—safflower oil, gelatin, vegetable glycerin, yellow beeswax, and soy lecithin—which serve as the capsule base and carrier.

Lutein listed on the label refers to the source or related compound; zeaxanthin is the component being supplied here.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health and blue light protection.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Zeaxanthin is rated "Insufficient Reliable Evidence To Rate" for Cataracts, Glaucoma, Asthenopia (eye strain), Macular telangiectasia type 2.

Zeaxanthin is possibly effective for age-related macular degeneration (AMD), an eye condition tied to aging. The evidence isn't strong enough to rate it for age-related cognitive decline, Alzheimer disease, asthma, breast cancer, or bronchopulmonary dysplasia.

If you're considering this supplement for AMD specifically, talk it over with your eye doctor or pharmacist to see if it fits your situation.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Zeaxanthin is generally well tolerated at typical supplement doses. For pregnancy, the safety data is limited—food sources of zeaxanthin are fine, but concentrated supplements during pregnancy haven't been well studied, so use caution and talk with your doctor or pharmacist before starting if you're pregnant.

Similarly, there isn't enough data on concentrated supplements while breastfeeding, though dietary sources are considered safe; check with your healthcare provider if you're nursing.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, zeaxanthin may theoretically increase the risk of low blood sugar. Check your exact medications with the tool on this page and confirm with your own doctor or pharmacist before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product is straightforward—one active ingredient with research backing its use for age-related eye disease. If you take antidiabetes medication, you'll want to confirm this is safe for you first.

Pregnant or breastfeeding? Discuss it with your doctor or pharmacist before adding it, since the concentrated form hasn't been thoroughly studied in those situations.

Otherwise, it's generally well tolerated.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein 40 mg, straight from the product label.

Brand Solgar
Barcode (UPC) 033984016774
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Apr 24, 2015
DSLD ID 44502
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein 40 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
033984016774
IngredientAmount% DV
Zeaxanthin2 mg--
Lutein40 mg--

Other ingredients: Safflower Oil, Gelatin, Vegetable Glycerin, yellow Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement for adults, take one (1) softgel daily, at mealtime, or as directed by a healthcare practitioner.

Precautions

If you are taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.

Keep out of reach of children.

Do not use if outer bottle seal is missing, torn or damaged in any way.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

FloraGLO LUTEIN (R)

(R) FloraGLO is a registered trademark of Kemin Industries, Inc.

(C)2010 Solgar, Inc.

General Statements

Scientific evidence indicates that Lutein helps filter out high energy blue-light from the sun and artificial light, which may otherwise induce oxidative stress and possible free-radical damage to the eyes and skin.Solgar’s Lutein 40 mg was developed to promote eye health, healthy skin and skin hydration.*

Since 1947

EYE HEALTH*

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

SOLGB15441 00B

Formulation

GLUTEN, WHEAT & DAIRY FREE

FREE OF: Gluten, Wheat, Dairy, Yeast, Sugar, Sodium, Artificial Flavor, Sweetener, preservatives and Color

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein 40 mg by Solgar label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein 40 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein 40 mg by Solgar

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lutein

No known
interactions
40 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Safflower Oil, Gelatin, Vegetable Glycerin, Yellow Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein 40 mg by Solgar Drug Interactions

Want to check YOUR meds against Lutein 40 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Lutein 40 mg interact with 86 drugs. Click any drug to see the details.

0 of the 1 ingredient in Lutein 40 mg interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein 40 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Lutein 40 mg, from the product label.

Solgar

See all Solgar products
Phone Number
1-877-765-4274
Web Address
www.solgar.com
Pharmacist Counseling Corner

Lutein 40 mg by Solgar: Common Questions

Does Lutein 40 mg by Solgar interact with any medications?
Yes. Based on its ingredients, Lutein 40 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein 40 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually work for eye health?
Zeaxanthin is possibly effective for age-related macular degeneration (AMD). For other conditions like cognitive decline or Alzheimer disease, the evidence isn't established enough for us to rate it. Talk with your eye doctor about whether it's right for your specific situation.
Can I take this if I'm pregnant?
Food sources of zeaxanthin are fine, but the safety of concentrated supplements during pregnancy hasn't been well studied. There isn't enough data to say it's definitely safe, so talk with your doctor or pharmacist before starting if you're pregnant.
Is it safe to breastfeed while taking this?
Dietary zeaxanthin from food is considered safe while breastfeeding, but we don't have enough data on concentrated supplements. Check with your doctor or pharmacist before taking it if you're nursing.
What are the side effects?
No adverse effects are documented in our data. Zeaxanthin is generally well tolerated when used at normal supplement doses.
Is there soy in this product?
Yes. The softgel contains soy lecithin as an inactive ingredient. If you have a soy allergy, this product isn't for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein 40 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein 40 mg label
Go deeper

The Full Monographs Behind Lutein 40 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Lutein 40 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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