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Dietary supplement

Lutein Ingredients & Drug Interactions

by DaVinci Laboratories Of Vermont

Lutein label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein is a dietary supplement by DaVinci Laboratories Of Vermont with 2 active ingredients. Its ingredients are commonly taken for eye and macular health, age-related macular degeneration (amd), protection from blue light.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lutein by DaVinci Laboratories Of Vermont

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein by DaVinci Laboratories Of Vermont — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lutein by DaVinci Laboratories Of Vermont

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: zeaxanthin and lutein. Both are carotenoids — naturally occurring pigments in plants — that concentrate in the eye, particularly in the retina and lens.

The product includes inactive ingredients (cellulose, vegetable cellulose, silicon dioxide, and vegetable stearate) as binders and capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and macular protection.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Zeaxanthin and lutein are possibly effective for age-related macular degeneration (AMD), the leading cause of vision loss in older adults. Lutein is also possibly effective for cataracts.

The evidence for both ingredients in other conditions — including age-related cognitive decline, Alzheimer's disease, asthma, and various forms of eye disease in premature infants — is either insufficient or points to no real benefit. Ask your eye doctor whether either ingredient makes sense for your particular situation.

The evidence, ingredient by ingredient Zeaxanthin Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both zeaxanthin and lutein are generally well tolerated at typical supplement doses. Lutein studies up to 20 mg daily have not reported adverse effects.

For pregnancy and breastfeeding, the safety data is rated likely safe, but the facts note that supplement safety specifically in pregnancy and breastfeeding hasn't been well studied — food sources are fine, but concentrated supplements warrant caution. Talk with your doctor or pharmacist if you're pregnant, nursing, or planning either.

Side effects, ingredient by ingredient Zeaxanthin Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drugs (insulin, metformin, sulfonylureas, or others), double-check this product with your doctor or pharmacist before starting — zeaxanthin may increase the risk of low blood sugar. For the ingredients we could fully check, that is the only documented interaction type.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a reasonable choice if you're interested in lutein and zeaxanthin for age-related eye health, especially AMD. The main caution is if you take diabetes medications — zeaxanthin may theoretically lower blood sugar further.

Pregnancy and breastfeeding safety data is incomplete, so check with your doctor or pharmacist before use if that applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein, straight from the product label.

Brand DaVinci Laboratories Of Vermont
Barcode (UPC) 026664226167
Net contents 60 Capsule(s); 10 mg
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22880
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein by DaVinci Laboratories Of Vermont, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
026664226167
IngredientAmount% DV
Zeaxanthin1 mg--
Lutein10 mg--

Other ingredients: Cellulose, Vegetable Cellulose, Silicon Dioxide, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

TRUTH We pledge total truth in labeling. Our family of products contain only the purest and most potent ingredients. Guaranteed.

Eye health can be affected by light radiation, sun exposure and dietary deficiencies. Lutein is an antioxidant carotenoid that is found in nature with Zeaxanthin. Both are especially concentrated in the macula of the eye. Dietary Lutein and Zeaxanthin help to support eye health by reducing this effects of oxidative stress to the macula and lense of the eye.

Color of this product may vary due to color variations of the natural ingredients.

10062300 0112

Precautions

Warning: If pregnant or nursing, consult your health care practitioner before taking this product.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule, 1-4 times daily with food or as directed by your health care practitioner.

General

0200261.060 0310A

FDA Statement of Identity

A Dietary Supplement to Support Eye Health

Formulation

VEGETARIAN

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein by DaVinci Laboratories Of Vermont label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein by DaVinci Laboratories Of Vermont

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Zeaxanthin

Interacts with
86 drugs
1 mg per serving

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

Lutein

No known
interactions
10 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Cellulose, Vegetable Cellulose, Silicon Dioxide, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein by DaVinci Laboratories Of Vermont Drug Interactions

Want to check YOUR meds against Lutein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Zeaxanthin 86

Individual Drug Interactions

The ingredients in Lutein interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lutein interact with drugs. Each result below shows which ingredient is responsible. Zeaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
Zeaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lutein, from the product label.

DaVinci Laboratories Of Vermont

See all DaVinci Laboratories Of Vermont products
Name
DaVinci Laboratories of Vermont a division of FoodScience Corp.
Street Address
20 New England Drive, Suite 10
City
Essex Junction
State
VT
ZipCode
05452
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

Lutein by DaVinci Laboratories Of Vermont: Common Questions

Does Lutein by DaVinci Laboratories Of Vermont interact with any medications?
Yes. Based on its ingredients, Lutein has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety rating is likely safe, but supplement doses of zeaxanthin and lutein haven't been well studied in pregnancy and breastfeeding — food sources are fine. Talk with your doctor or pharmacist about whether this particular supplement makes sense for you right now.
Does this actually help with macular degeneration?
Both zeaxanthin and lutein are possibly effective for age-related macular degeneration (AMD). That means there's reasonable evidence, but it's not definitive. Your eye doctor is the best person to tell you whether adding this supplement fits your treatment plan.
Are there any side effects?
Lutein at doses up to 20 mg daily hasn't caused adverse effects in studies, and both ingredients are generally well tolerated at typical supplement amounts. No specific adverse effects are documented in the data we hold.
What's the difference between zeaxanthin and lutein?
Both are carotenoid pigments that settle in your eyes and may protect against age-related damage. Lutein also has evidence for cataracts, while zeaxanthin's evidence is mainly for macular degeneration.
I take diabetes medication. Is this safe for me?
Zeaxanthin may theoretically increase the risk of low blood sugar (hypoglycemia) when taken with diabetes drugs. Before starting this product, check with your doctor or pharmacist — they can review your specific medications and let you know whether it's okay for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein label
Go deeper

The Full Monographs Behind Lutein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph →
Sources

Sources & How We Checked

Lutein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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