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Dietary supplement

Lutein + Zeaxanthin Ingredients & Drug Interactions

by SR Sports Research

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Lutein + Zeaxanthin is a dietary supplement by SR Sports Research with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Lutein + Zeaxanthin by SR Sports Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains 2 active ingredients: lutein and zeaxanthin, both carotenoids — plant pigments your eyes naturally use. They're the ones that give some vegetables their yellow and orange colors.

The product also includes coconut oil, tapioca starch, glycerin, and purified water as inactive ingredients to form and stabilize the softgel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health and filter blue light.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is rated possibly effective for age-related macular degeneration (AMD) and cataracts — two common eye conditions that come with age. It's rated possibly ineffective for retinitis pigmentosa, retinopathy of prematurity, necrotizing enterocolitis, and bronchopulmonary dysplasia.

Zeaxanthin is also rated possibly effective for AMD. For age-related cognitive decline, Alzheimer disease, asthma, breast cancer, and bronchopulmonary dysplasia, there isn't enough reliable evidence in our data to rate it either way.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated at typical supplement doses. Lutein at doses up to 20 mg daily has not caused adverse effects in trials.

Zeaxanthin has no adverse effects reported in the data we hold. For pregnancy and breastfeeding: the safety data rates both ingredients as likely safe.

That said, most of the evidence comes from food sources rather than concentrated supplements, so there isn't enough studied data on higher supplement doses during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, check them against our search tool before starting — zeaxanthin may theoretically increase the risk of low blood sugar. For all other medications in our data, no interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're concerned about age-related eye changes like macular degeneration or cataracts, lutein and zeaxanthin are possibly effective options backed by research. If you take an antidiabetes medication, check your specific drugs with our search tool first, since zeaxanthin may theoretically affect blood sugar.

Your pharmacist can help you decide if this fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein + Zeaxanthin, straight from the product label.

Brand SR Sports Research
Barcode (UPC) 023249012108
Net contents 120 Veggie Softgel(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 326264
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein + Zeaxanthin by SR Sports Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Liquid Veggie Softgel
Maximum serving Sizes:
1 Liquid Veggie Softgel
Servings per container
120
UPC/BARCODE
023249012108
IngredientAmount% DV
Lutein20 mg--
Zeaxanthin4 mg--

Other ingredients: Coconut Oil, Tapioca Starch, Modified, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

SR Lutein + Zeaxanthin features Lute-Gen and is derived from marigold flowers. Concentrated in the macular region of the eye, these two vibrantly colored carotenoid pigments may help filter high-energy blue light & support eye health. Vegan certified PlantGel Made with Lute-gen Lutein

Made with coconut oil 20mg Lutein 4mg Zeaxanthin

Formulation

Vegan certified PlantGel

Non-GMO project verified

Satisfaction Guarantee We offer a full refund on the purchase price of your order (minus return cost) within 90 days of purchase. Restrictions apply. Please visit sportsresearch.com for full details. Track your lot number, and view third party independent testing. SPORTSRESEARCH.COM

Manufactured and Quality Tested in USA. Ingredients carefully sourced from around the world.

Certified Vegan Vegan.org

Gluten free Non GMO Project Verified nongmoproject.org

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Money Back Guarantee 90 Days

Certified Vegan Vegan.org Good Manufacturing Practice cGMP Compliant 3rd Party Tested Quality Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, healthy adults take 1 Liquid Veggie Softgel daily with food. Best when taken as directed by a qualified healthcare professional.

Precautions

Contains: Tree nuts (Coconut).

Caution: Keep out of reach of children and pets.

Consult with a qualified healthcare professional prior to using this product, especially if you are pregnant, nursing, have diagnosed medical conditions, or are taking prescription medications.

Do not exceed recommended daily intake. Do not use if safety seal is damaged or missing.

Brand IP Statement(s)

Lute-gen is a registered trademark of Bio-gen extracts Pvt. Ltd.

Storage

Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity and light.

General Statements

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See for yourself

Lutein + Zeaxanthin by SR Sports Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lutein + Zeaxanthin by SR Sports Research

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Liquid Veggie Softgel Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
20 mg per serving Form: Lute-Gen

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Zeaxanthin

Interacts with
86 drugs
4 mg per serving Form: Lute-Gen

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

Other (inactive) ingredients: Coconut Oil, Tapioca Starch, Modified, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein + Zeaxanthin by SR Sports Research Drug Interactions

Want to check YOUR meds against Lutein + Zeaxanthin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein + Zeaxanthin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Lutein + Zeaxanthin, from the product label.

SR Sports Research

See all SR Sports Research products
Name
Sports Research
Street Address
784 Channel St.
City
San Pedro
State
CA
ZipCode
90731
Phone Number
(310) 519-1484
Web Address
sportsresearch.com
Pharmacist Counseling Corner

Lutein + Zeaxanthin by SR Sports Research: Common Questions

Does Lutein + Zeaxanthin by SR Sports Research interact with any medications?
Yes. Based on its ingredients, Lutein + Zeaxanthin has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein + Zeaxanthin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the difference between lutein and zeaxanthin?
Both are carotenoids your body uses to protect your eyes. They're found in leafy greens and colorful vegetables, and they work similarly — the main difference is where they settle in your eye. This product gives you both.
Can I take this if I'm pregnant or breastfeeding?
The data rates both ingredients as likely safe in pregnancy and breastfeeding, but most evidence comes from food sources, not concentrated supplements. There isn't enough studied data on higher doses from pills, so talk with your doctor or pharmacist before you start — they can advise based on your situation.
How much lutein is safe to take daily?
Doses up to 20 mg of lutein daily haven't caused adverse effects in trials. This product's exact dose per softgel isn't listed in the data we hold, so check the label or ask your pharmacist to confirm it's right for you.
Does this product have fillers?
Yes — the softgel contains coconut oil, tapioca starch, glycerin, and purified water as inactive ingredients to form the capsule and keep everything mixed together.
Can this help with cataracts?
Lutein is rated possibly effective for cataracts based on the evidence we hold, so it may help — but possibly effective means the research is promising, not certain. Talk with your eye doctor about whether this fits into your eye health plan.
Are there any side effects at normal doses?
Lutein is generally well tolerated at typical supplement doses with no reported adverse effects. Zeaxanthin also has no adverse effects reported in our data. Both are generally well tolerated when used as directed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein + Zeaxanthin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein + Zeaxanthin label
Sources

Sources & How We Checked

Lutein + Zeaxanthin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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