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Dietary supplement

Lycopene & Lutein Complex 50 mg Ingredients & Drug Interactions

by NusaPure

Lycopene & Lutein Complex 50 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lycopene & Lutein Complex 50 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lycopene & Lutein Complex 50 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene and Lutein Proprietary Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lycopene & Lutein Complex 50 mg by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Lycopene & Lutein Complex 50 mg by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lycopene & Lutein Complex 50 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Lycopene and Lutein Proprietary Complex” is a proprietary blend — the label gives one combined amount (50 mg) without saying how much of each component you get.

This product contains 2 active ingredients: lycopene and lutein. Lycopene is a red pigment (carotenoid) found in tomatoes and other red fruits, and lutein is a yellow pigment (xanthophyll carotenoid) found in leafy greens and other vegetables.

Both are plant compounds your body doesn't make on its own, so they come from diet or supplements. The capsule also contains inactive ingredients — cellulose, silica, magnesium stearate, and rice flour — which help hold and deliver the active ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Lycopene) (Natural Medicines).
  • On file: Age-related macular degeneration (AMD) — rated "Possibly Effective" (Lutein) (Natural Medicines).
  • On file: Cataracts — rated "Possibly Effective" (Lutein) (Natural Medicines).

Lycopene is possibly effective for prostate cancer, but the evidence is considered possibly ineffective for bladder cancer and diabetes. For high cholesterol (hyperlipidemia), exercise-triggered asthma, and ALS, there is not enough reliable evidence to rate it either way.

Lutein is possibly effective for age-related macular degeneration (vision loss as you age) and cataracts. For retinitis pigmentosa, vision problems in premature infants, and two other rare eye and lung conditions, it is considered possibly ineffective, and the evidence is insufficient for the remaining conditions listed in our data.

The evidence, ingredient by ingredient Lycopene Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. However, if you're pregnant, the safety data on lycopene supplements is limited — food amounts are fine, but talk with your doctor before taking a supplement.

The same goes for breastfeeding: food amounts are okay, but there isn't enough safety data on supplement doses. Lutein from food and typical supplement doses is generally well tolerated — doses up to 20 mg daily have not caused adverse effects in trials.

For pregnancy and breastfeeding, lutein is considered likely safe. Lycopene and lutein supplements can cause mild digestive side effects, including diarrhea, gas, bloating, nausea, vomiting, or indigestion in some people.

Side effects, ingredient by ingredient Lycopene Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any anticoagulant or antiplatelet medication — including prescription blood thinners like warfarin or dabigatran, or over-the-counter aspirin — check with your doctor or pharmacist before adding this product. Lycopene may increase the bleeding risk when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're interested in eye health (lutein) or prostate support (lycopene), though the evidence for these uses is modest. If you take blood thinners or antiplatelet drugs, you'll need to check with your doctor or pharmacist before starting — lycopene can theoretically increase bleeding risk.

Talk it over with your healthcare provider to see if it fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lycopene & Lutein Complex 50 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001KRFUR1
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 307342
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lycopene & Lutein Complex 50 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
200
UPC/BARCODE
X001KRFUR1
IngredientAmount% DV
Lycopene0 NP--
Lutein0 NP--
Lycopene and Lutein Proprietary Complex50 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Lycopene and Lutein Complex 50mg

General Statements

New

Please recycle.

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) capsule daily with a fat-containing meal.

Precautions

Warning: If pregnant, nursing or taking any medications, consult your physician before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not eat freshness packet. Keep in bottle.

Not intended for use by persons under the age of 18.

Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place after opening.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium quality Assembled in USA GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility

Manufactured in a cGMP inspected facility

Formulation

GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility

Assembled in USA Tested Supports nutritional supplementation Made under strict GMP guidelines Max strength

Suitable for vegetarians/vegans

Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lycopene & Lutein Complex 50 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lycopene & Lutein Complex 50 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lycopene & Lutein Complex 50 mg by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

Lycopene and Lutein Proprietary Complex

Interacts with
122 drugs
50 mg per serving

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene and Lutein Proprietary Complex monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lycopene & Lutein Complex 50 mg by NusaPure Drug Interactions

Want to check YOUR meds against Lycopene & Lutein Complex 50 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene and Lutein Proprietary Complex 122

Individual Drug Interactions

The ingredients in Lycopene & Lutein Complex 50 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lycopene & Lutein Complex 50 mg interact with drugs. Each result below shows which ingredient is responsible. Lycopene and Lutein Proprietary Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Lycopene & Lutein Complex 50 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene and Lutein Proprietary Complex1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene and Lutein Proprietary Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lycopene & Lutein Complex 50 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central, LLC
Street Address
500 Westover Dr. #92909
City
Sanford
State
NC
ZipCode
27330
Pharmacist Counseling Corner

Lycopene & Lutein Complex 50 mg by NusaPure: Common Questions

Does Lycopene & Lutein Complex 50 mg by NusaPure interact with any medications?
Yes. Based on its ingredients, Lycopene & Lutein Complex 50 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lycopene & Lutein Complex 50 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Lycopene supplements have limited safety data in pregnancy and breastfeeding — food amounts are fine, but the safety of supplements hasn't been well studied, so talk with your doctor first. Lutein is considered likely safe during pregnancy and breastfeeding based on available data.
What does lutein actually do?
Lutein is a yellow plant pigment that concentrates in the retina (the light-sensing part of your eye). Research shows it's possibly effective for age-related macular degeneration and cataracts — two conditions that cloud or damage vision as you age.
What's lycopene used for in this supplement?
Lycopene is the red pigment in tomatoes. This product uses it because research suggests it may be possibly effective for prostate cancer, though the evidence is still being built.
Could this supplement upset my stomach?
Yes, lycopene supplements can cause digestive side effects like diarrhea, gas, bloating, nausea, or indigestion in some people. Lutein is generally well tolerated even at higher doses.
Does this product have any fillers or other ingredients I should know about?
The capsule contains inactive ingredients — cellulose, silica, magnesium stearate, and rice flour — which are common binders and flow agents. If you have sensitivities to any of these, check the label or talk with your pharmacist.
Will this help my vision?
Lutein in this product is possibly effective for age-related macular degeneration and cataracts. If you have other eye concerns or conditions, talk with your doctor about whether this supplement makes sense for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lycopene & Lutein Complex 50 mg label
Go deeper

The Full Monographs Behind Lycopene & Lutein Complex 50 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph →
Sources

Sources & How We Checked

Lycopene & Lutein Complex 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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