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Dietary supplement

Reishi Mushroom 3600 mg Ingredients & Drug Interactions

by NusaPure

Reishi Mushroom 3600 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Reishi Mushroom 3600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Reishi Mushroom 3600 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mushroom extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Reishi Mushroom 3600 mg by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Reishi Mushroom 3600 mg by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Reishi Mushroom 3600 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: reishi mushroom extract at 3600 mg per serving. Reishi (also called lingzhi) is a fungus used in traditional medicine, and the extract concentrates its active compounds.

The capsule also contains inactive ingredients—cellulose, silica, magnesium stearate, and rice flour—which are standard binders and fillers that help form and preserve the capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Reishi Mushroom product and its label doesn't state a use — see Reishi Mushroom's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for reishi mushroom is limited. For lowering cholesterol (hyperlipidemia), it's rated possibly ineffective—meaning the data doesn't support that use.

For altitude sickness, Alzheimer disease, and athletic performance, there isn't enough reliable evidence to rate it either way. If you're considering this product for a specific health goal, the data we hold doesn't establish that it works for most of those purposes.

The evidence, ingredient by ingredient Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, reishi mushroom is generally well tolerated in the short term, but long-term safety hasn't been well studied, so we don't know what happens if you take it for months or years. The most common side effects are dizziness, dry mouth, itching, nausea, rash, and stomach upset.

Some people report respiratory allergy to reishi spores, including sore throat and runny nose. Rare side effects include insomnia and headache.

During pregnancy and breastfeeding, there isn't enough safety data, so it's best avoided—talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Reishi Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel)—this product may increase bleeding risk at this dose. Also confirm if you're on blood pressure medications or diabetes drugs, since reishi might add to their effects and cause your pressure or blood sugar to drop too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Reishi mushroom may be worth considering if you're interested in traditional mushroom supplements and don't take blood thinners, blood pressure medications, or diabetes drugs. If you do take any of those, or if you're pregnant or nursing, check with your doctor or pharmacist first.

The evidence for specific health claims is weak or absent in our data, so be clear about what you're hoping it will do.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reishi Mushroom 3600 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001O8XN0R
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246920
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reishi Mushroom 3600 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
100
UPC/BARCODE
X001O8XN0R
IngredientAmount% DV
Reishi Mushroom extract900 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, preferably with meals.

Precautions

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Contains no artificial coloring, artificial flavor, salt, sodium, sugar, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Allergen Information: Suitable for vegetarians.

Allergen Information: Contains no artificial coloring, artificial flavor, salt, sodium, sugar, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Natural Supports healthy heart Supports healthy aging Supports immune system Helps support longevity Max Strength

Natural color variation may occur in this product.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility.

Formula

Reishi mushroom 3600 mg equivalent per serving

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Reishi Mushroom 3600 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Reishi Mushroom 3600 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Reishi Mushroom 3600 mg by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Reishi Mushroom extract

Interacts with
375 drugs
900 mg per serving

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi Mushroom extract monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reishi Mushroom 3600 mg by NusaPure Drug Interactions

Want to check YOUR meds against Reishi Mushroom 3600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

Reishi Mushroom extract 375

Individual Drug Interactions

The ingredients in Reishi Mushroom 3600 mg interact with 375 drugs. Click any drug to see the details.

1 of the 1 ingredient in Reishi Mushroom 3600 mg interact with drugs. Each result below shows which ingredient is responsible. Reishi Mushroom extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Reishi Mushroom 3600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Mushroom extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Mushroom extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Reishi Mushroom 3600 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Reishi Mushroom 3600 mg by NusaPure: Common Questions

Does Reishi Mushroom 3600 mg by NusaPure interact with any medications?
Yes. Based on its ingredients, Reishi Mushroom 3600 mg has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reishi Mushroom 3600 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is reishi mushroom extract?
Reishi is a fungus used in traditional medicine for centuries. This product contains a concentrated extract of it in capsule form. The extract pulls out the active compounds from the mushroom so you get a higher dose per capsule.
Can I take this if I'm on blood pressure medication?
Not without checking first. Reishi has shown blood pressure-lowering effects in some people, so combining it with your blood pressure drug could theoretically lower your pressure too much. Talk with your doctor or pharmacist before adding it.
Is it safe to take long-term?
Short-term use is generally well tolerated, but long-term safety hasn't been well studied. If you're thinking about taking it regularly for months or longer, discuss that timeline with your doctor or pharmacist.
Can I take this while breastfeeding?
There isn't enough safety data to know, so it's best avoided while nursing. Talk with your doctor or pharmacist about whether it's right for you in this situation.
What are the most common side effects?
The most common are dizziness, dry mouth, itching, nausea, rash, and stomach upset. Some people also report respiratory allergy symptoms like sore throat and runny nose.
Will this help me lose weight or lower my cholesterol?
For cholesterol, the evidence suggests it's likely not effective. We don't have reliable data for weight loss either. If you're considering reishi for a specific health goal, check with your doctor about whether the evidence supports that use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reishi Mushroom 3600 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reishi Mushroom 3600 mg label
Go deeper

The Full Monographs Behind Reishi Mushroom 3600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Reishi Mushroom 3600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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