Manuka Honey Lozenges Lemon Ingredients & Drug Interactions
by Be Magic
What is this page for?
First and foremost: checking Manuka Honey Lozenges Lemon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Manuka Honey Lozenges Lemon is a dietary supplement by Be Magic with 3 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 981 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Manuka Honey, Vitamin C, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Manuka Honey Lozenges Lemon by Be Magic
Ask about any prescription or over-the-counter medication and we check it for interactions with Manuka Honey Lozenges Lemon by Be Magic — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Manuka Honey Lozenges Lemon by Be Magic
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Be Magic Manuka Honey Lozenges Lemon contains 3 active ingredients: vitamin C, sodium, and manuka honey. Vitamin C is an antioxidant nutrient; sodium is an essential mineral; and manuka honey is a type of honey from New Zealand with a long history of use in traditional medicine.
The lozenges also contain inactive ingredients—sugar, glucose syrup, water, lemon flavoring, citric acid, and additional ascorbic acid (a form of vitamin C)—which serve as sweeteners, flavoring, and preservatives.
Does it work?
Couldn't assess
Vitamin C in this product is effective for preventing vitamin C deficiency and is possibly effective for anemia of chronic disease, atrial fibrillation, cataracts, and respiratory infections related to exercise. Manuka honey is possibly effective for cold sores, cough, mouth sores from cancer treatment, burns, and dry eye.
Sodium's effectiveness is only established for cystic fibrosis (likely effective) and amphotericin B kidney damage (possibly effective); the evidence is insufficient to rate it for bipolar disorder or congestive heart failure.
How safe is it?
Well-documented data
Vitamin C is generally well tolerated at normal dietary and supplement doses, but very high doses can cause abdominal cramps, heartburn, diarrhea, nausea, and kidney stones in those prone to them—especially above 2 grams daily. Sodium is safe in usual dietary amounts but too much is linked to high blood pressure and heart strain; avoid sodium supplements or very high intake without medical advice.
Manuka honey is generally safe for adults and children over 1 year old and is likely safe in pregnancy and while breastfeeding as food, but if you plan to use honey medicinally, check with your doctor first. Rare allergic reactions to honey, including anaphylaxis, have been reported.
Honey from Turkey's Black Sea coast can contain toxins from rhododendrons and should be avoided.
Meds to double-check
Moderate interaction found
Before starting this product, check with your doctor or pharmacist if you take any of these: blood thinners or antiplatelet drugs (the honey and vitamin C may increase bleeding risk); birth control or hormone replacement therapy (vitamin C may raise estrogen levels); chemotherapy drugs like cyclophosphamide or doxorubicin (vitamin C may reduce their effect); blood pressure medications (sodium may reduce their effectiveness); lithium (sodium changes can affect lithium levels and cause toxicity); the anti-seizure drug phenytoin; thyroid medication levothyroxine; or corticosteroids. These represent the most serious documented interactions.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
These lozenges may help with vitamin C intake and provide the benefits of honey for cough and sore throat, though the amount of each active ingredient per lozenge isn't specified in our data. If you take blood thinners, birth control, blood pressure medication, lithium, or any chemotherapy drug, talk with your doctor or pharmacist before using this product.
The sodium content is also worth flagging if you're on a sodium-restricted diet or taking medications sensitive to sodium changes.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Manuka Honey Lozenges Lemon, straight from the product label.
| Brand | Be Magic |
|---|---|
| Barcode (UPC) | 9421905820110 |
| Net contents | 15 Lozenge(s); 2.44 Ounce(s); 69 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 304003 |
| Product type | Other Combinations |
| Supplement form | Lozenge |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Manuka Honey Lozenges Lemon by Be Magic, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin C | 4.5 mg | 4.5% |
| Calories | 18 Calorie(s) | -- |
| Total Carbohydrate | 3.8 Gram(s) | 2% |
| Sugars | 3 Gram(s) | 2% |
| Sodium | 1.6 Gram(s) | -- |
| Manuka Honey | 300 mg | -- |
Other ingredients: Sugar, Glucose syrup, Water, Lemon, Citric Acid, Ascorbic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
At Be Magic we are excited to bring a synergy of two unique Mother Nature gifts such as Manuka Honey MGO500+ and lemon for your everyday wellbeing. New Zealand untouched wilderness provides with zillion of natural products with beneficial properties. Lemons Lemons are high in vitamin C, fibre and various beneficial plant compounds. Based on Ayurveda medicine books these beneficial nutrients are in support of a general wellbeing. As well, ancient folks believed lemons may support heart and digestive health. Plant compounds found lately in lemons by scientific lab tests - namely hesperidin and diosmin - have also been found to lower cholesterol at mice. Lemons are often promoted as a weight loss food by some orthodox naturopaths with a few undocumented theories as to how it works. One common believe is based on soluble pectin fiber found plenty in lemons expands in stomach helping you feel full for longer. Animal studies show that lemon extract and fruit compounds may promote weight loss, but the effect in humans are unknown. Manuka Honey Original from New Zealand the monofloral Manuka Honey with 500+ mg/kg of Methylglyoxal that we use to create our lozenges is well known for its unique properties found in the great amount in no other honey in the world.
Manuka Honey MGO500+ Lozenges with the natural flavor of Lemon
FDA Disclaimer Statement
These statements have not been evaluated by the US FDA. This product is not intended to diagnose, cure, treat or prevent any diseases.
Suggested/Recommended/Usage/Directions
Suggested use: One lozenge orally as needed up to 6 times a day. Do not consume more than recommended.
Precautions
Do not consume more than recommended.
Keep off of reach by children.
Do not give to children under 5 y.o.
Warning: Diabetics and allergy sufferers should ask their physician advice before consumption.
Warning: Diabetics and allergy sufferers should ask their physician advice before consumption.
Choking warning: Lozenges may lodged in the throat.
Choking warning: Lozenges may lodged in the throat. Do not give lozenges to minors under 5 y.o.
Storage
Store in cool & dry place below room temperature (24 degrees C/75 degrees F)
Formulation
Products of New Zealand
Authentic 100% New Zealand
Not a significant source of calories from fat, saturated fat, trans fat, cholesterol, dietary fiber, Vitamin A, C, calcium or iron.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Manuka Honey Lozenges Lemon by Be Magic label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Manuka Honey Lozenges Lemon by Be Magic
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Lozenge(s) Dosage formLozenge Servings per container15 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin C
Interacts with207 drugs
Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...
Vitamin C monograph & interactionsSodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsManuka Honey
Interacts with736 drugs
Honey is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade or Manuka...
Manuka Honey monograph & interactionsOther (inactive) ingredients: Sugar, Glucose syrup, Water, Lemon, Citric Acid, Ascorbic Acid. These complete the product’s ingredient list but are not active constituents.
Manuka Honey Lozenges Lemon by Be Magic Drug Interactions
HelloPharmacist Interaction Report
Be Magic Manuka Honey Lozenges Lemon interacts with medications through its vitamin C, sodium, and manuka honey content.
The most serious interaction is vitamin C's potential to reduce the effectiveness of chemotherapy drugs (alkylating agents and antitumor antibiotics), which carry Major concern. Vitamin C also has Moderate interactions with blood thinners like warfarin, where high doses may lower their effectiveness, and with estrogens (including birth control and hormone replacement therapy), where vitamin C may increase estrogen levels by up to 55% in some cases.
Read the full breakdown — every affected drug type, severity by severity
Sodium in this product has Moderate interactions with blood pressure medications, where high sodium intake may reduce their effectiveness, and with lithium, where sodium changes can alter lithium levels and cause toxicity. Sodium also interacts with corticosteroids, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs, raising the risk of high blood sodium levels.
Additionally, vitamin C interacts with the anti-seizure drug phenytoin (potentially raising levels), the HIV drug indinavir (modestly reducing levels), the antipsychotic fluphenazine (theoretically decreasing levels), and thyroid medication levothyroxine (increasing absorption). Honey has Minor interactions with anticoagulant or antiplatelet drugs, where it may theoretically increase bleeding risk, and with drugs metabolized by the liver enzyme CYP3A4, though research on honey's effect here is conflicting.
Although we could not fully verify every potential interaction with all medications, you should check your exact prescriptions against our medication interaction tool below before starting this product—especially if you take blood thinners, birth control, blood pressure drugs, lithium, chemotherapy, or thyroid medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Manuka Honey Lozenges Lemon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Manuka Honey Lozenges Lemon interact with 981 drugs. Click any drug to see the details.
3 of the 3 ingredients in Manuka Honey Lozenges Lemon interact with drugs. Each result below shows which ingredient is responsible. Manuka Honey Vitamin C Sodium
AcebutololRhotral, Sectral
How Acebutolol interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acetazolamide interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Alginic Acid, Aluminum Hydroxide interactionAliskirenTekturna
How Aliskiren interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aliskiren interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Aliskiren interactionAltretamineHexalen
How Altretamine interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionManuka HoneyAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionManuka HoneyAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium Hydroxide (otc Drug) interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ambrisentan interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Benzoate interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besilate interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate, Benazepril interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine, Celecoxib interactionManuka HoneyCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Read the full Manuka Honey + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aprocitentan interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Manuka Honey Lozenges Lemon — through 2 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionManuka HoneyAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Manuka Honey + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAtenololAtenix, Tenormin
How Atenolol interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Manuka Honey Lozenges Lemon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlorthalidone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Manuka Honey Lozenges Lemon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Manuka Honey
Phenytoin (Dilantin)
Theoretically, honey might increase levels of phenytoin.
In an animal model, the rate and extent of absorption of phenytoin was increased by honey. This effect has not been reported in humans.
Anticoagulant/Antiplatelet Drugs
Theoretically, honey may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro, honey inhibits platelet aggregation and increases the time to clotting. Furthermore, animal research suggests that feeding mice large doses of honey for 12 days increases bleeding time when compared with no intervention. However, these effects have not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, honey might decrease levels of drugs metabolized by CYP3A4, but research is conflicting.
Some clinical research shows that honey induces CYP3A4. However, other clinical studies found no effect on CYP3A4 activity. Different honey preparations may have different effects on CYP3A4.
Vitamin C
Alkylating Agents
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Aluminum
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.
Antitumor Antibiotics
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.
Estrogens
Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.
Fluphenazine (Prolixin)
Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.
Indinavir (Crixivan)
Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.
Levothyroxine (Synthroid, Others)
Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.
Warfarin (Coumadin)
High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.
Acetaminophen (Tylenol, Others)
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.
Aspirin
Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.
Choline Magnesium Trisalicylate (Trilisate)
Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Niacin
Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.
Salsalate (Disalcid)
Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Manuka Honey Lozenges Lemon, from the product label.
Be Magic
See all Be Magic products- Name
- Carte Blanche WCA, Inc.
- City
- Brooklyn
- State
- NY
- ZipCode
- 11229
- Phone Number
- 1-646-402-4558
- Web Address
- www.beemagicusa.com
Manuka Honey Lozenges Lemon by Be Magic: Common Questions
Does Manuka Honey Lozenges Lemon by Be Magic interact with any medications?
How can one product interact with so many drugs?
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What side effects might I get from these lozenges?
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Can I use this if I'm taking warfarin (a blood thinner)?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Manuka Honey Lozenges Lemon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin C
Interacts with 207 drugsVitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...
Read the full Vitamin C monograph → Herb & supplement monographSodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographHoney
Interacts with 736 drugsHoney is a natural food with some real, modest evidence for easing coughs and helping certain wounds, especially when special medical-grade or Manuka honey is used. It is generally safe for...
Read the full Honey monograph →Sources & How We Checked
Manuka Honey Lozenges Lemon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 129 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin C 51 references
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Sodium 38 references
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