Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Meratrim 1234 Ingredients & Drug Interactions

by Creative Bioscience

Meratrim 1234 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Meratrim 1234 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Meratrim 1234 is a dietary supplement by Creative Bioscience with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, anti-inflammatory support, immune support.Based on those ingredients, 125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia mangostana (fruit rind) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Meratrim 1234 by Creative Bioscience

Ask about any prescription or over-the-counter medication and we check it for interactions with Meratrim 1234 by Creative Bioscience — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Meratrim 1234 by Creative Bioscience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Meratrim(R) Proprietary Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

Meratrim 1234 contains 2 active ingredients: Sphaeranthus indicus flower extract and Garcinia mangostana (mangosteen) fruit rind extract, combined in a proprietary blend. The product also includes inactive ingredients (cellulose, hydroxypropyl methylcellulose, magnesium stearate, and silica) that serve as capsule filler and binder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Mangosteen's overall clinical evidence instead.

Moderate

Some clinical evidence supports Mangosteen for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Periodontitis — rated "Possibly Effective" (Natural Medicines).

Mangosteen has been studied for several conditions. It's rated possibly effective for periodontitis (gum disease), though the evidence is modest.

For androgenic alopecia (male-pattern hair loss) and Alzheimer disease, there isn't enough reliable evidence to say whether it helps. Data on its use for atopic dermatitis (eczema) is also insufficient.

We have no effectiveness information on file for Sphaeranthus indicus.

The evidence, ingredient by ingredient Mangosteen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mangosteen is generally well tolerated as a food, but the long-term safety of concentrated supplement amounts hasn't been well studied. At doses up to 560 mg daily, some people reported mild tiredness, headache, dizziness, malaise, constipation, nausea, vomiting, diarrhea, dry throat, cough, and flu-like symptoms — though it's unclear whether mangosteen actually caused these or they occurred by chance.

Safety data advises against using this product during pregnancy or while breastfeeding. We don't have interaction or safety data on file for Sphaeranthus indicus.

Side effects, ingredient by ingredient Mangosteen

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mangosteen.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 125 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners and antiplatelet drugs are the main concern — mangosteen may increase your bleeding risk. Also double-check if you take donepezil for Alzheimer disease, as mangosteen could raise its levels in your brain.

Since we couldn't verify Sphaeranthus indicus, mention all ingredients to your pharmacist when you pick up your other medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people interested in weight management or skin health, but the evidence for most claims is limited or absent. If you take blood thinners, antiplatelet drugs, or donepezil, talk with your doctor or pharmacist before starting it — mangosteen can affect how these work.

If you're pregnant, nursing, or on any prescription medication, check with your own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Meratrim 1234, straight from the product label.

Brand Creative Bioscience
Barcode (UPC) 816907011175
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42568
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Meratrim 1234 by Creative Bioscience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
816907011175
IngredientAmount% DV
Sphaeranthus indicus (flower heads) extract0 NP--
Garcinia mangostana (fruit rind) extract0 NP--
Meratrim(R) Proprietary Blend400 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Vegetable (Magnesium) Stearate, Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, take one (1) capsule twice daily 30 minutes before breakfast and dinner with a full glass of water. For best results, drink plenty of water throughout the day. Do not exceed the maximum recommended dose.

Precautions

WARNING: Use only as suggested.

Not intended for use by anyone under the age of 18, pregnant, nursing, and/or if the packaging is broken.

Consult a physician before use if you or a family member has been diagnosed with any medical conditions. Discontinue use and contact a physician if you experience any unusual symptoms.

KEEP OUT OF REACH OF CHILDREN.

Brand IP Statement(s)

Meratrim(R) brand proprietary blend of two natural plant extracts. Meratrim(R) is exclusively distributed by InterHealth N.I

General

Formula #202055 / 2306361

General Statements

Clinically Proven Ingredients

1234 Diet Program Live Diet Support

Seals/Symbols

Stimulant Free

cb

{American flag}

Non-GMO

All Natural

MERATRIM(R)

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Meratrim 1234 by Creative Bioscience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Meratrim 1234 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Meratrim 1234 by Creative Bioscience

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Meratrim(R) Proprietary Blend

400 mg per serving

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Vegetable (Magnesium) Stearate, Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Meratrim 1234 by Creative Bioscience Drug Interactions

Want to check YOUR meds against Meratrim 1234?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
125Drugs
122 Moderate 3 Minor

Ingredients driving the most interactions

Garcinia mangostana (fruit rind) extract 125

Individual Drug Interactions

The ingredients in Meratrim 1234 interact with 125 drugs. Click any drug to see the details.

1 of the 2 ingredients in Meratrim 1234 interact with drugs. Each result below shows which ingredient is responsible. Garcinia mangostana (fruit rind) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Meratrim 1234 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Garcinia mangostana (fruit rind) extract2 drug types · 125 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
In vitro and animal research shows that gamma-mangostin, a constituent of mangosteen, is a potent and competitive antagonist of the serotonin 2A (5-HT2A) receptor. Antagonism of the 5-HT2A receptor is believed to reduce platelet aggregation.

Likelihood Possible Evidence D
Donepezil (Aricept)

Theoretically, concomitant use of mangosteen with donepezil might increase the effects of donepezil.
Animal research shows that concomitant use of an aqueous extract of mangosteen pericarp with donepezil increases brain concentrations of donepezil at 4 hours by 64% without associated effects on systemic exposure.

Likelihood Possible Evidence D
Garcinia mangostana (fruit rind) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Meratrim 1234, from the product label.

Creative Bioscience

See all Creative Bioscience products
Phone Number
877-744-1224
Pharmacist Counseling Corner

Meratrim 1234 by Creative Bioscience: Common Questions

Does Meratrim 1234 by Creative Bioscience interact with any medications?
Yes. Based on its ingredients, Meratrim 1234 has a known interaction with 125 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Meratrim 1234 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Meratrim and what's it supposed to do?
Meratrim is a two-ingredient blend of extracts from Sphaeranthus indicus and mangosteen fruit rind. It's marketed for weight management and related goals, but the evidence showing it works is limited or not yet established in our data.
Does mangosteen really work for anything?
Mangosteen is rated possibly effective for periodontitis (gum disease) based on available research. For hair loss, Alzheimer disease, and eczema, there isn't enough reliable evidence yet to say whether it helps.
Can I take this if I'm pregnant or breastfeeding?
No — safety data advises against using this product during pregnancy or while nursing. Talk with your doctor or pharmacist about safer options if you're expecting or nursing a baby.
What side effects might I get from mangosteen?
At typical supplement doses, people have reported tiredness, headache, dizziness, nausea, vomiting, constipation, diarrhea, dry throat, and cough — though it's not certain mangosteen caused them. These aren't common, but they're worth knowing about.
Can I take this with blood thinners like warfarin?
Not without checking with your doctor first. Mangosteen in this product may increase bleeding risk when combined with blood thinners and antiplatelet drugs. Your healthcare provider needs to weigh the benefits and risks for you personally.
I'm on donepezil for memory — is this product okay for me?
Check with your doctor before starting. Mangosteen can raise how much donepezil reaches your brain, which might make the drug stronger than usual. Your doctor can tell you whether that's safe for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Meratrim 1234 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Meratrim 1234 label
Go deeper

The Full Monographs Behind Meratrim 1234’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mangosteen

Interacts with 125 drugs

Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supplements for inflammation, immune support...

Read the full Mangosteen monograph →
Sources

Sources & How We Checked

Meratrim 1234's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mangosteen 6 references
  1. Chairungsrilerd N, Furukawa K, Ohta T, et al. Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana. Planta Med 1996;62:471-2.
  2. Wong LP, Klemmer PJ. Severe lactic acidosis associated with juice of the mangosteen fruit Garcinia mangostana. Am J Kidney Dis 2008;51:829-33. PubMed
  3. Furukawa, K., Chairungsrilerd, N., Ohta, T., Nozoe, S., and Ohizumi, Y. [Novel types of receptor antagonists from the medicinal plant Garcinia mangostana]. Nippon Yakurigaku Zasshi 1997;110 Suppl 1:153P-158P. PubMed
  4. Chairungsrilerd, N., Furukawa, K., Tadano, T., Kisara, K., and Ohizumi, Y. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998
  5. Suthammarak W, Numpraphrut P, Charoensakdi R, et al. Antioxidant-enhancing property of the polar fraction of mangosteen pericarp extract and evaluation of its safety in humans. Oxid Med Cell Longev 2016;2016:1293036. PubMed
  6. Bae M, Han SY, Kim ES, et al. Effect of Water Extract of Mangosteen Pericarp on Donepezil Pharmacokinetics in Mice. Molecules 2021;26(17):5246. PubMed

See these in context on the Mangosteen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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