Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

'Merica 'Minos Blood, Sweat, and Tears Ingredients & Drug Interactions

by 'Merica Labz

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

'Merica 'Minos Blood, Sweat, and Tears is a dietary supplement by 'Merica Labz with 5 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of 'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Branched-Chain Amino Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

'Merica 'Minos Blood, Sweat, and Tears is a 5-ingredient powder built around branched-chain amino acids (BCAAs) — which include L-leucine, L-isoleucine, and L-valine — plus L-citrulline and elevATP. BCAAs are amino acids your muscles use directly during and after exercise; L-citrulline is converted in your body to L-arginine, which supports nitric oxide production and blood vessel function. elevATP is a proprietary ingredient meant to support cellular energy.

The powder also contains inactive ingredients: citric acid, natural and artificial flavors, sucralose, and acesulfame-K.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle support and athletic performance.
  • We looked for evidence on: Athletic performance, Muscle strength, Sarcopenia, muscle endurance, training support.
  • The strongest evidence on file: L-citrulline is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: L-citrulline is rated "Possibly Ineffective" for Sarcopenia.
  • Also on file: L-citrulline is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

L-citrulline is possibly effective for athletic performance, meaning some evidence supports its use, though the data isn't conclusive. For sarcopenia (age-related muscle loss), it's rated possibly ineffective.

The evidence on L-citrulline for cardiovascular disease, heart failure, Reye syndrome, and diabetes is insufficient to rate, so we can't say whether it helps for those conditions. We hold no effectiveness data for L-leucine, L-isoleucine, L-valine, or elevATP.

The evidence, ingredient by ingredient L-citrulline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-citrulline is generally well tolerated in healthy adults, though long-term safety hasn't been fully studied. The most common side effects are gastrointestinal discomfort and heartburn.

A small number of people with pulmonary hypertension reported cough while taking it. Safety data during pregnancy and breastfeeding is not sufficient, so the guidance is to avoid this supplement if you're pregnant or nursing; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient L-citrulline

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — L-citrulline.
  • The most serious interaction on file is rated Moderate.
  • For scale: 178 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your list before taking this product if you use blood pressure medications (antihypertensive drugs) or erectile dysfunction drugs (phosphodiesterase-5 inhibitors). Both can have additive effects with L-citrulline, potentially lowering your blood pressure too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help athletic performance, but its strength for other uses isn't established. The real concern is L-citrulline's potential to lower blood pressure further or intensify the effects of erectile dysfunction drugs, which matters if you take either of those types.

If you're on any blood pressure medication or PDE-5 inhibitor, confirm with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 'Merica 'Minos Blood, Sweat, and Tears, straight from the product label.

Brand 'Merica Labz
Barcode (UPC) 602573098257
Net contents 16.3 Ounce(s); 463 Gram(s)
Market status On market
Date entered into DSLD Feb 26, 2020
DSLD ID 213479
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
18.5 Gram(s)
Maximum serving Sizes:
18.5 Gram(s)
Servings per container
25
UPC/BARCODE
602573098257
IngredientAmount% DV
L-Leucine8000 mg--
L-Isoleucine2000 mg--
L-Citrulline3000 mg--
L-Valine2000 mg--
Branched-Chain Amino Acids0 NP--
elevATP300 mg--

Other ingredients: Citric Acid, Natural and Artificial flavors, Sucralose, Acesulfame-K

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

That on this day, in the year of our Lord, all muscles held as slaves to catabolism within any body, the person whereof shall then be in rebellion against the muscle loss, shall be then, thenceforward, and forever jacked. Abraham Lincoln wrote that on January 1, 1863 - proclaiming freedom to all muscles from the tyranny of catabolism. Ok, he didn't. We wrote that. Literally just now. But if Honest Abe had known about the most muscle-sparingest, catabolism-f-you'ing-est, freest frickin' amino acid product this side of the Mason-Dixon, we're sure his words would've been similar.

Never Big Enough

Precautions

Warning: This product is only intended for use in healthy adults 18 years of age or older.

Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Mix 1 scoop with 16-32 ounces of water and shake well. Consume immediately before and during training. Additional servings can be taken throughout the day.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Amino Acid Proclamation

Formulation

Naturally & Artificially Flavored

Manufactured in a U.S. cGMP Facility

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

elevATP Strength. Power. Performance

elevATP is a registered trademark of VDF FutureCeuticals, Inc., used under license.

See for yourself

'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size18.5 Gram(s) Dosage formPowder Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Citrulline

Interacts with
178 drugs
3000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

Branched-Chain Amino Acids

0 NP per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

ElevATP

300 mg per serving Form: Ancient Peat, Apple extract

Other (inactive) ingredients: Citric Acid, Natural and Artificial flavors, Sucralose, Acesulfame-K. These complete the product’s ingredient list but are not active constituents.

Interaction report

'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz Drug Interactions

Want to check YOUR meds against 'Merica 'Minos Blood, Sweat, and Tears?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
178Drugs
178 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in 'Merica 'Minos Blood, Sweat, and Tears with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for 'Merica 'Minos Blood, Sweat, and Tears, from the product label.

'Merica Labz

Name
'Merica Labz, LLC
State
Virginia
Phone Number
1-844-445-5335
Web Address
www.MericaLabz.com
Pharmacist Counseling Corner

'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz: Common Questions

Does 'Merica 'Minos Blood, Sweat, and Tears by 'Merica Labz interact with any medications?
Yes. Based on its ingredients, 'Merica 'Minos Blood, Sweat, and Tears has a known interaction with 178 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
'Merica 'Minos Blood, Sweat, and Tears contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me build muscle?
L-citrulline is possibly effective for athletic performance, but the evidence isn't conclusive. The branched-chain amino acids in here are used by muscle, though we don't have effectiveness ratings for them individually from our data.
Can I take this if I'm pregnant or breastfeeding?
The safety data for L-citrulline during pregnancy and breastfeeding is not adequate, so the guidance advises against it. Talk with your doctor or pharmacist to decide what's right for your situation.
What are the side effects?
L-citrulline is generally well tolerated, with the most common side effects being gastrointestinal discomfort and heartburn. A small number of people with pulmonary hypertension reported cough.
What does L-citrulline actually do?
Your body converts L-citrulline into L-arginine, which increases nitric oxide — a chemical that helps relax blood vessels and improve blood flow. That's why it's linked to blood pressure and how it can interact with certain medications.
I'm on blood pressure medication. Can I use this?
L-citrulline in this product may lower your blood pressure further, adding to your medication's effect. Talk with your doctor or pharmacist before starting to see if it's safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 'Merica 'Minos Blood, Sweat, and Tears is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

'Merica 'Minos Blood, Sweat, and Tears label
Go deeper

The Full Monographs Behind 'Merica 'Minos Blood, Sweat, and Tears’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

'Merica 'Minos Blood, Sweat, and Tears's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-citrulline 8 references
  1. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
  3. Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
  4. Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
  5. Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
  7. Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

See these in context on the L-citrulline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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