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Dietary supplement

Methyl Folate 1000 mcg Ingredients & Drug Interactions

by Superior Source

Methyl Folate 1000 mcg label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Methyl Folate 1000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Methyl Folate 1000 mcg is a dietary supplement by Superior Source with 2 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Methyl Folate 1000 mcg by Superior Source

Ask about any prescription or over-the-counter medication and we check it for interactions with Methyl Folate 1000 mcg by Superior Source — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Methyl Folate 1000 mcg by Superior Source

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: stevia leaf extract and folate (in the form of methyl folate, 1000 mcg per dose). Stevia is a plant-derived sweetener, while folate is a B vitamin your body uses for cell division and DNA synthesis.

The tablet also contains inactive ingredients — lactose, natural cherry flavor, and acacia — which serve as filler, flavor, and binder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for stevia's effectiveness in lowering blood sugar, blood pressure, or weight is insufficient to establish whether it works for these purposes. Folate effectiveness ratings are not on file in our data, so we can't speak to its specific benefits here.

If you're considering this product for a particular health goal, talk with your doctor or pharmacist about what the science actually supports.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Stevia is generally well tolerated when taken by mouth. Minor side effects like abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness may occur, but most resolve within the first week.

Allergic reactions are rare but possible. Because high-dose stevia supplements lack extensive safety data, use caution — purified stevia at food amounts is considered safer than whole-leaf or supplement doses.

We don't have pregnancy or breastfeeding safety information on file for either ingredient in this product, so talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding before starting.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your doctor or pharmacist if you take lithium — stevia may raise its levels (Moderate concern). Also check if you're on blood pressure medications or diabetes drugs, since stevia might intensify their effects (Minor concerns).

No interactions are documented for the folate in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Methyl Folate 1000 mcg is generally well tolerated, but the stevia content means you should check it with your doctor or pharmacist if you take lithium, blood pressure medications, or diabetes drugs before starting. If you're pregnant, breastfeeding, or have questions about whether this is right for you, discuss it with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Methyl Folate 1000 mcg, straight from the product label.

Brand Superior Source
Net contents 60 MicroLingual(R) Instant Dissolve Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 56735
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Methyl Folate 1000 mcg by Superior Source, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 MicroLingual(R) Tablet(s)
Maximum serving Sizes:
1 MicroLingual(R) Tablet(s)
Servings per container
60
IngredientAmount% DV
Stevia leaf extract1 mg--
Folate1000 mcg250%

Other ingredients: Lactose, natural Cherry flavor, Acacia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, dissolve one MicroLingual tablet under the tongue as directed by your healthcare provider. This product may also be swallowed or chewed.

Seals/Symbols

MicroLingual

GMO FREE

FDA Statement of Identity

DIETARY SUPPLEMENT

General

ITEM # 90250 30473J P02 R00

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Methyl Folate 1000 mcg by Superior Source label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Methyl Folate 1000 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Methyl Folate 1000 mcg by Superior Source

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 MicroLingual(R) Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Stevia leaf extract

Interacts with
259 drugs
1 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia leaf extract monograph & interactions

Folate

1000 mcg per serving Form: L-5 Methyltetrahydrofolate

Other (inactive) ingredients: Lactose, Natural Cherry flavor, Acacia. These complete the product’s ingredient list but are not active constituents.

Interaction report

Methyl Folate 1000 mcg by Superior Source Drug Interactions

Want to check YOUR meds against Methyl Folate 1000 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia leaf extract 259

Individual Drug Interactions

The ingredients in Methyl Folate 1000 mcg interact with 259 drugs. Click any drug to see the details.

1 of the 2 ingredients in Methyl Folate 1000 mcg interact with drugs. Each result below shows which ingredient is responsible. Stevia leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Methyl Folate 1000 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia leaf extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Methyl Folate 1000 mcg, from the product label.

Superior Source

See all Superior Source products
Name
Superior Source
City
Los Angeles
State
CA
Phone Number
(800) 421-6175
Web Address
www.superiorsourcevitamins.com
Pharmacist Counseling Corner

Methyl Folate 1000 mcg by Superior Source: Common Questions

Does Methyl Folate 1000 mcg by Superior Source interact with any medications?
Yes. Based on its ingredients, Methyl Folate 1000 mcg has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Methyl Folate 1000 mcg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure or diabetes medication?
Stevia in this product may theoretically enhance the effects of both types of medications, which could lower your blood pressure too much or raise your risk of low blood sugar. Check with your doctor or pharmacist before starting to make sure it's safe alongside your specific drugs.
What side effects might I experience?
The most common are abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness. Most of these resolve within the first week. Allergic reactions are rare but possible.
Is this safe to take if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for either ingredient in this product. Talk with your doctor or pharmacist before taking it if you're pregnant, planning pregnancy, or breastfeeding — they can give you personalized advice.
What is methyl folate and why is it in here?
Methyl folate is a form of folate, a B vitamin your body needs for cell division and DNA synthesis. It's the active vitamin form in this product.
Does stevia actually lower blood sugar or blood pressure?
The evidence isn't strong enough yet to say for sure. Some studies suggest stevia extract may lower blood sugar after meals, but other research doesn't find it lowers blood pressure significantly in people with high blood pressure. We'd rate the evidence as insufficient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Methyl Folate 1000 mcg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Methyl Folate 1000 mcg label
Go deeper

The Full Monographs Behind Methyl Folate 1000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Methyl Folate 1000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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