B-1 100 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking B-1 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
B-1 100 mg is a dietary supplement by Superior Source with 2 active ingredients. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 262 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract, Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against B-1 100 mg by Superior Source
Ask about any prescription or over-the-counter medication and we check it for interactions with B-1 100 mg by Superior Source — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of B-1 100 mg by Superior Source
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients. Thiamine (vitamin B-1) is an essential vitamin your body needs for energy production and nerve function.
Stevia leaf extract is a no-calorie sweetener derived from the stevia plant. The inactive ingredients — lactose, natural flavors, and acacia — are fillers and binders that make up the tablet.
Does it work?
Strong evidence
Thiamine is effective for treating thiamine deficiency and Wernicke-Korsakoff syndrome, a serious brain condition caused by severe thiamine shortage. It's possibly effective for period pain (dysmenorrhea), though the evidence is limited.
For heart failure and as a mosquito repellent, thiamine is possibly ineffective based on available data. Stevia's effectiveness for diabetes, high blood pressure, and weight loss is unclear — we don't have enough reliable evidence to say whether it works for those uses.
How safe is it?
Well-documented data
Thiamine is generally very safe when taken by mouth in normal amounts. Serious side effects are rare — allergic reactions like skin rashes can happen but are uncommon.
The safety data supports thiamine in pregnancy and breastfeeding when used at recommended doses under your provider's guidance, since it's actually needed during those times. Purified stevia in food amounts is generally recognized as safe.
However, this product delivers stevia as a high-dose supplement, and long-term safety data for that form isn't well established, so caution is warranted. Minor side effects reported in studies — bloating, dizziness, headache, muscle pain, nausea, numbness — usually resolve after the first week.
Allergic reactions are rare.
Meds to double-check
Moderate interaction found
Check your medications if you take lithium — stevia may raise its levels dangerously (Moderate interaction). Also verify any trimethoprim antibiotics, blood pressure drugs, or diabetes medications, since stevia and thiamine have documented Minor interactions with those types.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is straightforward for most people who need a thiamine supplement and don't mind a stevia-sweetened tablet. If you take lithium, trimethoprim, blood pressure medications, or diabetes drugs, check with us or your doctor first.
Pregnant or breastfeeding? Thiamine is actually needed during those times, but talk with your provider about whether you need a supplement or can get enough from food.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about B-1 100 mg, straight from the product label.
| Brand | Superior Source |
|---|---|
| Net contents | 100 MicroLingual(R) Instant Dissolve Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Feb 24, 2017 |
| DSLD ID | 70857 |
| Product type | Botanical With Nutrients |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for B-1 100 mg by Superior Source, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Thiamine | 100 mg | 6670% |
| Stevia leaf extract | 2 mg | -- |
Other ingredients: Lactose, Natural Flavors, Acacia
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
No shot
Our proprietary hydrodrying process results in fewer inactive binders and fillers and a higher ratio of nutritional ingredients - hence the small size. They efficiently provide your body with the nutrients you need right now.
"Less is more" Simplicity Purity Efficiency No pills to swallow
Dissolves immediately on contact
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Our instant Dissolve MicroLingual Tablets may be small but they are full potency! Typical tablets and capsules need to be swallowed and are inefficiently absorbed in the digestive system. MicroLingual tablets dissolve immediately under the tongue heading straight into the body.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, dissolve one MicroLingual tablet under the tongue as directed by your healthcare provider. This product may also be swallowed.
Place on or under the tongue
Formulation
Preservative free
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
B-1 100 mg by Superior Source label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in B-1 100 mg by Superior Source
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 MicroLingual(R) Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Thiamine
Interacts with3 drugs
Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...
Thiamine monograph & interactionsStevia leaf extract
Interacts with259 drugs
Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...
Stevia leaf extract monograph & interactionsOther (inactive) ingredients: Lactose, Natural Flavors, Acacia. These complete the product’s ingredient list but are not active constituents.
B-1 100 mg by Superior Source Drug Interactions
HelloPharmacist Interaction Report
Superior Source B-1 100 mg contains thiamine and stevia leaf extract, and both have documented interactions with certain medications.
Read the full breakdown — every affected drug type, severity by severity
Thiamine interacts with trimethoprim (an antibiotic used for urinary tract infections and other bacterial infections). Trimethoprim can block how your kidneys and liver normally clear thiamine, which may raise thiamine levels in your blood — a Minor interaction.
Stevia leaf extract has a more serious concern: it may reduce how your body clears lithium (used for bipolar disorder), potentially raising lithium levels to unsafe amounts. This is a Moderate interaction.
Additionally, stevia might theoretically lower blood pressure when combined with blood pressure medications or increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medications — both Minor interactions, though the blood pressure effect is inconsistent in studies.
Altogether, these interactions span 259 individual medications. If you take trimethoprim, lithium, blood pressure drugs, or diabetes medications, use the interaction checker below to verify your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
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Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in B-1 100 mg interact with 262 drugs. Click any drug to see the details.
2 of the 2 ingredients in B-1 100 mg interact with drugs. Each result below shows which ingredient is responsible. Stevia leaf extract Thiamine
Lithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractLithium Moderate
Interaction Summary
Theoretically, stevia might decrease clearance and increase levels of lithium.
Read the full Stevia Leaf Extract + Lithium Carbonate (prescription Drug) interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Ammonium Chloride interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Stevia Leaf Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAprocitentanTryvio
How Aprocitentan interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with B-1 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Read the full Stevia Leaf Extract + Bendroflumethiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in B-1 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Stevia leaf extract
Lithium
Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.
Antidiabetes Drugs
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.
Antihypertensive Drugs
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.
Thiamine
Trimethoprim (Proloprim)
Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.
Brand information
Manufacturer and brand details for B-1 100 mg, from the product label.
Superior Source
See all Superior Source products- Name
- Continental Vitamin Co. Superior Source
- City
- Los Angeles
- State
- CA
- ZipCode
- 90058
- Phone Number
- (800) 421-6175
- Web Address
- www.superiorsource1.com
B-1 100 mg by Superior Source: Common Questions
Does B-1 100 mg by Superior Source interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is thiamine safe to take while I'm pregnant or breastfeeding?
What is thiamine, and what does it do in my body?
Does this product actually work for diabetes or blood pressure?
What are the side effects of this supplement?
Why does this tablet contain stevia if I'm just buying it for thiamine?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if B-1 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind B-1 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Thiamine
Interacts with 3 drugsThiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...
Read the full Thiamine monograph → Herb & supplement monographStevia
Interacts with 259 drugsStevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...
Read the full Stevia monograph →Sources & How We Checked
B-1 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Thiamine 7 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
- Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
- Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
- Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.
Stevia 10 references
- Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
- Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
- Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
- Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
- Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
- Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
- Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
- Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
- Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
- Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC